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Prenatal autism
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition influenced by genetic, environmental, and maternal health factors during pregnancy. This study investigates the prenatal risk factors associated with ASD, including maternal stress, metabolic syndrome, exposure to pesticides and anti-epileptic drugs, and nutritional deficiencies, while also exploring evidence-based preventive measures such as a healthy maternal diet, supplementation with essential nutrients (e.g., vitamin D, iron, folic acid), and avoidance of environmental toxins.
Novel mouse model for future autism research
Autism spectrum disorder (ASD) is a set of neurodevelopmental disorders characterized by a deficit in social behaviors and nonverbal interactions such as reduced eye contact, facial expression, and body gestures in the first 3 years of life. It is not a single disorder, and it is broadly considered to be a multi-factorial disorder resulting from genetic and non-genetic risk factors and their interaction. Genetic studies of ASD have identified mutations that interfere with typical neurodevelopment in utero through childhood. These complexes of genes have been involved in synaptogenesis and axon motility. Recent developments in neuroimaging studies have provided many important insights into the pathological changes that occur in the brain of patients with ASD in vivo. Especially, the role of amygdala, a major component of the limbic system and the affective loop of the cortico-striatothalamo-cortical circuit, in cognition and ASD has been proved in numerous neuropathological and neuroimaging studies.
