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Ibuprofen : Pharmacology, Therapeutics and Side Effects
Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.
Gastric ulcers the cases and treatment
A gastric ulcer also known as stomach ulcer is an excoriated area of stomach caused principally by the digestive action of gastric juice Secretion in many ways the most common reasons are the taking non steroid anti-inflammatory drugs (NSAID) or an infection with Helicobacter pylori bacteria. It used to be Thought that stress or certain foods or drinking alcohol and smoking tobacco might cause stomach ulcer but in less cases. stomach ulcer can affect people of any age, including children, but mostly occur in people aged 50 or over. the common symptom is the pain in stomach and nausea with or without vomiting. the diagnosis through endoscopy is the best method to be sure about ulcer. the treatment of ulcer according to the reasons of ulcer is caused bacteria or not gastric ulcer It occurs in 80% of cases with the level of curvature The little one, especially the angle and antra, and effect men and women are the same.
Drug repurposing : A new fashion for a new hope
The repurposing of drugs is becoming increasingly attractive as it avoids the long process and cost implications associated with bringing a novel drug to market i.e., drug repurposing is cost effective and time saving. This study will discuss the repositioning of several drugs that belong to different pharmaceutical classifications such as antimicrobials (itraconazole and fluoroquinolones), anti-diabetic agents (metformin and sodium glucose co-transporter 2 inhibitors), cardiovascular drugs (β-blockers and digoxin), anticonvulsants (topiramate), immunosuppressants (sirolimus), non-steroidal anti-inflammatory drugs (NSAIDs e.g., COX inhibitors), and cholesterol lowering drugs (statins).
