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The book begins with a historical introduction to the field of bioprocess control based on artificial intelligence approaches, followed by two chapters covering the optimization of fed-batch culture using genetic algorithms. Online biomass soft-sensors are constructed in Chapter 4 using recurrent neural networks. The bioprocess is then modelled in Chapter 5 by cascading two soft-sensor neural networks. Optimization and validation of the final product are detailed in Chapters 6 and 7. The general conclusions are drawn in Chapter 8.
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