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Lysosomes
This book summarizes the current state-of-the art knowledge about this unique organelle. It addresses the biogenesis of this compartment, the transport of lysosomal proteins, the role of the lysosomal membrane in lysosomal stability and transport, the function of lysosomal proteases and hydrolases, lysosomal storage disorders, and new concepts on how to treat these diseases.
Lysosomal Storage Disorders
This book is dedicated to patients affected by Lysosomal Storage Disorders, and especially to the National Gaucher Foundation (USA) and the Colombian Association of Patients with Lysosomal Storage Diseases (ACOPEL for its Spanish Acronym). Both organizations will share in the sales of this book.
Lung biology and pathophysiology
The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics.
Longs COVID-19 patients
Nearly 250 million people around the world have recovered from Covid-19. But here, the word "recovered" refers only to the acute phase of the illness. Approximately 10 and 40 percent of Covid patients continue to experience symptoms several weeks to months after falling sick, a nebulous condition now referred to as post-Covid condition, or long Covid. In long Covid, we are witnessing the emergence of a legitimate new illness, officially recognized by the World Health Organization's International Classification of Diseases...
Liver MRI : Correlation with other Imaging Modalities and Histopathology
In this seminal manuscript the - thor described a new imaging technique which moved the single dimension of NMR spectroscopy to the dual dimension of spatial orientation, thereby resulting in the foundation of modern magnetic re- nance (MR) imaging. Over the ensuing years, MR imaging has assumed an increasingly important role in clinical imaging. It distinguishes itself from other imaging modalities, such as ultrasound (US) or computed tomography (CT), by the unique ability to visualize specific tissue components in a non-- vasive manner. In the earlier days, diagnostic MR imaging was limited to cerebral and musculoskeletal diseases. - aging of other areas which are more prone to movement through breathing (abdominal) or pulsation motions (cardiac) became available more recently, with the introduction of faster sequences and the - velopment of more dedicated MR imaging coils.
Liver Immunology : Principles and Practice
parasitic and viral infections of the liver, autoimmune liver disease, alcoholic and nonalcoholic fatty liver diseases, and transplantation in an easy-to-read and thorough format. Authors also address the key issues that have arisen in this field in recent years, including physiological roles of hepatocytes, sinusoidal lining cells, activated macrophages (Kupffer cells), cholangiocytes and stellate cells, and their modulation of T cells, natural killer (NK) cells and NKT cells.
Liver and Pancreatic Diseases Management
New therapeutical approaches, advances in oncology and in diagnostic imaging, which reduce the need for invasive techniques and reach an improvement in survival and quality of life in cancer, are considered in this book. Modern literature has been reviewed with special reference to articles of general interest. In the clinical management of patients with liver, bile duct and pancreas diseases, it is important to assess the degree of disturbance and to diagnose the causative insult, and therefore clinical and laboratory methods of assessing each of these pathologies are of high interest. This version is an up-to-date account of diseases of the liver, biliary tract and pancreas, including transplantation, which we trust will be of value for surgeons, physicians and pathologists and also a reference book for medical students.
Liver
Liver is the second largest organ in human body, more than 5,000 separate bodily functions including helping blood to clot, cleansing the blood of toxins to converting food into nutrients to control hormone levels, fighting infections and illness, regenerating back after injury and metabolizing cholesterol, glucose, iron and controlling their levels. Most people never give their liver a thought until something goes wrong, yet, liver diseases on rise, affecting one in ten. Liver diseases can be inherited or caused by a variety of factors that damage the liver.
Little and Falace's Dental Management of the Medically Compromised Patient ; 9th ed.
Learn how to provide dental care to any patient, regardless of existing medical conditions. Little and Falace’s Dental Management of the Medically Compromised Patient, 9th Edition, has been thoroughly revised to give you the information you need to assess common problems, and make safe and healthy dental management decisions. The new addition includes expanded coverage of women’s health issues and introduces a process for developing a medical-risk source. Also, each chapter features vivid illustrations and well-organized tables to give you in-depth details and overall summaries to help you get to the root of your future patients’ needs.
Lippincott illustrated reviews : Pharmacology
Presents up-to-date drug information in an accessible format ideal for a fast, effective refresher. Part of the popular Lippincott® Illustrated Reviews series, this concise resource features clear, effective writing and hundreds of illustrations that break down complex information for rapid review. Sequential images present mechanisms of action and focus on showing rather than telling students how drugs work, and review questions with answers deliver powerful, practical exam preparation. Updated drug information reflects the most current, clinically relevant pharmacology material. Approachable outline format distills complex information for easier review. High-quality illustrations reinforce understanding in vibrant detail. Enhanced review questions with answers test students' understanding and identify areas for further study.
Lindhe's Clinical Periodontology and Implant Dentistry ; 2 Vol. Set ; 7th ed.
Provides an introduction to anatomy, including periodontal tissues, the edentulous ridge, the mucosa at teeth and implants, and osseointegration Discusses the epidemiology of periodontal and peri-implant diseases Explores the microbiology, including dental biofilms and calculus, periodontal infections, peri-implant infections, the pathogenesis of gingivitis and periodontitis, and the genetic susceptibility to periodontal disease Includes the latest perio- and peri-implant disease classifications Contains updated evidence-based preventive and treatment modalities for the treatment of periodontal and peri-implant diseases Features the latest evidence-based therapeutic alternatives on the use of dental implants to rehabilitate the lost dentition
Lifestyle psychiatry through the lens of behavioral medicine
Lifestyle medicine is a practice which adopts evidence-based lifestyle interventions as a primary modality to prevent, treat, and reverse chronic diseases. The six main pillars of this specialty include physical activity, nutrition, stress resilience, cessation or risk reduction of substance use, quality sleep, and connectivity. Lifestyle psychiatry is a rapidly emerging area within healthcare informed by rigorous research within the social and biological sciences, public health, and medicine. A volume in the Lifestyle Medicine series, this book uses a comprehensive biopsychosocial approach to prevent and treat psychiatric disorders and promote mental and physical well-being through evidence-based lifestyle interventions.
Lifestyle nutrition eating for good health by lowering the risk of chronic diseases
Provides physicians with an evidence-based introduction to nutrition science with a practical emphasis on how to apply this information to improve the health of their patients and enhance their own lives. From nutrition and atherosclerosis to erectile dysfunction and chronic kidney disease to osteoporosis, this comprehensive guide covers a wide range of conditions influenced by diet. It delves into specialized areas, such as nutrition for physically active people to the elderly, ensuring relevance for diverse patient populations. The reader will find detailed analysis of the Dietary Guidelines for Americans 2020–2025 and their applications and strategies for adopting healthy plant-based diets, such as Mediterranean, DASH, and vegan.
Lifestyle nursing
Examines the concepts of lifestyle medicine and nursing practice, it is specifically designed to help nurses introduce the concepts of lifestyle medicine to readers while also encouraging them to focus on their own wellness. This book features nutritional guidelines and supplemental materials operationalizing this basic nutrition knowledge into personal and patient wellness. It addresses evidence-based findings of chronic diseases including heart diseases and stroke, type 2 diabetes, and cancers, which can often be prevented by lifestyle interventions.
Lifestyle modifications : The best treatment for prediabetes
Demonstrate the physiological effects of lifestyle modification on prediabetes. Prediabetes is a condition in which individuals have blood glucose levels higher than normal but not high enough to be classified as diabetes. Prediabetes is now recognized as a reversible condition that increases an individual’s risk for development of diabetes. Lifestyle risk factors for prediabetes include overweight and physical inactivity.
Leveraging Data Science for Global Health
Explores ways to leverage information technology and machine learning to combat disease and promote health, especially in resource-constrained settings. It focuses on digital disease surveillance through the application of machine learning to non-traditional data sources.
Les thérapies ciblées = Targeted therapies
We are at the start of the development of new therapeutic classes, directed against new molecular targets (EGFR, VEGF, IGFR, Rank, etc.) Several diseases such as kidney, colon or breast cancer, GIST, have a natural history now modified thanks to these therapies. This practical book takes stock of the current use of these molecules.
Les infections urinaires = Urinary tract infections
Les Infections urinaires provides an update on knowledge concerning the epidemiology of community-based infection, on the mechanisms of bacterial resistance and on certain aspects of the disease useful to urologists as well as infectious diseases, gynecologists, emergency physicians and attending physicians. . Nosocomial urinary tract infection is approached from the perspective of risk factors. Acute and chronic prostatitis was the subject of a consensus conference supported by the World Health Organization within the framework of the International Consensus Conferences in Urology in Paris. The full text and the recommendations are reported with the consent of their authors. This book is an author's book and not an author's book because urinary tract infection is multiple, complex and justifies a multidisciplinary approach.
Les infections intra-abdominales aiguës = Acute intra-abdominal infections
Paradoxically, serious intra-abdominal infections are the forgotten ones in the world of infectious diseases. Paradoxical, because they are very common pathologies, affecting all age groups of the population and often life-threatening; paradoxical, because they concern many medical specialties through intensive care, gastroenterology, hepatology, imaging, infectious diseases, emergencies and surgery. Hence the need, thanks to an interdisciplinary collaboration, to publish a book in French bringing together all infectious abdominal pathologies, thus offering a synthesis of recent data from the literature in this field. This document should allow the various specialties concerned to find updates integrating the latest clinical, diagnostic and therapeutic data. Specialty interns and practitioners in the field will find something to establish an effective and up-to-date strategy for the management of patients with these pathologies, the high incidence of which and the severity of which is too often overlooked, it is important to remember.
Legionella Pneumophila : Pathogenesis and Immunity
Legionella pneumophila is an emerging human pathogen that resides in natural environments as a parasite of freshwater. The volume brings together all of the lastest research on this pathogen, the interest in which is rapidly growing.
