Lung biology and pathophysiology

Lung biology and pathophysiology

Author
Yutong Zhao
Publication Year
2024
Publisher
CRC Press
Language
English
Document Type
Book
Faculty / Subject Heading
Medical Science

The lungs are the organ for gas exchange between the body and the external environment. Dysfunction of upper airway epithelium and smooth muscle cells leads to pathogenesis of asthma, chronic obstructive pulmonary disease (COPD), cystic fibrosis, and other conditions, resulting in airway inflammation and narrowing. Injury to alveolar epithelium and endothelium causes influx of neutrophil and protein-rich fluid from circulation, resulting in edema and disruption of gas exchange. In addition to lung structural cells, immune cells, including alveolar macrophages and lymphocytes play critical roles in the maintenance of lung function. This book contributes to the understanding homeostasis of lung cells in the physiological and pathological conditions critical to the development of novel therapeutics.


Keywords: Bioscience / Medicine / Dentistry / Nursing and allied health / Lungs cytology / Lungs cytopathology / Lungs diseases - Pathogenesis / Lungs diseases - Ttreatment / Lungs histopathology