KRAS : Methods and protocols
- Author
- Andrew G. Stephen and Dominic Esposito
- Publication Year
- 2024
- Publisher
- Springer
- Language
- English
- Document Type
- Book
- Faculty / Subject Heading
- Medical Science
- Download Book Read book
Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.
Keywords: Cancer - Research / Chemistry / Food science - General / Biomedical and life sciences / GTPase activity / Mass spectrometry / Post-translational modifications / KRAS membrane diffusion / Lipid bilayers
