KRAS : Methods and protocols
- المؤلف
- Andrew G. Stephen and Dominic Esposito
- سنة النشر
- 2024
- الناشر
- Springer
- لغة الملف
- انكليزي
- نوع الملف
- Book
- تصنيف الكتاب
- Medical Science
- تحميل الكتاب قراءة الكتاب
Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.
الكلمات المفتاحية: Cancer - Research / Chemistry / Food science - General / Biomedical and life sciences / GTPase activity / Mass spectrometry / Post-translational modifications / KRAS membrane diffusion / Lipid bilayers