KRAS : Methods and protocols

KRAS : Methods and protocols

المؤلف
Andrew G. Stephen and Dominic Esposito
سنة النشر
2024
الناشر
Springer
لغة الملف
انكليزي
نوع الملف
Book
تصنيف الكتاب
Medical Science

Details protocols ranging from high yield production metabolically labeled KRAS for NMR studies to approaches that quantify engagement of novel molecules that bind KRAS in live cells. Chapters focus on protein production and characterization, biochemical assays, cell-based assays, KRAS-membrane interactions, targeting KRAS, and cell models.


الكلمات المفتاحية: Cancer - Research / Chemistry / Food science - General / Biomedical and life sciences / GTPase activity / Mass spectrometry / Post-translational modifications / KRAS membrane diffusion / Lipid bilayers