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Human microbiome : Clinical implications and therapeutic interventions

The human microbiome refers to the complete microorganisms inhabiting the human body sites including skin, ear, nose, oral cavity, the genital, gastrointestinal and respiratory tracts, and body fluids such as breast milk, saliva, and urine. It is a significant and essential organ recognized for the body and has an established involvement in the host wellbeing, in terms of nutritional requirements and immunomodulation. Talks about how alteration and imbalance in the same can have clinical implications associated with a multitude of gastrointestinal, lifestyle-associated, and neurodegenerative disorders. How the proliferation of specific groups of bacteria and their metabolic activities, as a result of intestinal dysbiosis leads to the 'leaky gut' condition thereby influences brain activity via the bidirectional gut-brain axis. It also coves the importance of microbial seeding and how it can be influenced by the mode of delivery, nutrition, and medication. This book also provides various therapeutic interventions such as the establishment of stool banks and Faecal microbiota transplantation (FMT) that have recently proved promising in the treatment of ASD, Inflammatory Bowel Disease, and Ulcerative Colitis. This book provides a deeper understanding of the development of the human gut microbiome and the factors driving its dysbiosis. This book is a valuable read for health professionals, medical students, nutritionists, and scientific research communities who are eager to update themselves with recent trends in microbiome research. It will also aid gastroenterologists and nutritionists to make well-informed choices regarding therapeutic regimes.

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Honey and olive oil in diabetic foot therapy

At the beginning of the 21st Century diabetic foot is Observed, although eminently preventable, represent one of the commonest causes of hospital inpatient in Western countries. Diabetic foot is a pathological condition that might affect the feet in patients with diabetes. Foot ulcers are defined as lesions involving a skin break with loss of epithelium: they can extend into the dermis and deeper layers sometimes involving bone and muscle...

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Gastric ulcers the cases and treatment

A gastric ulcer also known as stomach ulcer is an excoriated area of stomach caused principally by the digestive action of gastric juice Secretion in many ways the most common reasons are the taking non steroid anti-inflammatory drugs (NSAID) or an infection with Helicobacter pylori bacteria. It used to be Thought that stress or certain foods or drinking alcohol and smoking tobacco might cause stomach ulcer but in less cases. stomach ulcer can affect people of any age, including children, but mostly occur in people aged 50 or over. the common symptom is the pain in stomach and nausea with or without vomiting. the diagnosis through endoscopy is the best method to be sure about ulcer. the treatment of ulcer according to the reasons of ulcer is caused bacteria or not gastric ulcer It occurs in 80% of cases with the level of curvature The little one, especially the angle and antra, and effect men and women are the same.

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Fundamentals of Geriatric Medicine : A Case-Based Approach

This handbook addresses the complexity of disease prevention and presentation in elderly patients, as well as geriatric pharmacology. Medicare and Medicaid, and conditions common to elderly patients, including depression, dementia, and hypertension, are also covered. Numerous graphs and tables are included throughout the book to assist the reader in processing the information presented and incorporating it into clinical practice. This practical guide is an essential resource for all those caring for the elderly.

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Focus on bacterial biofilms

Bacterial biofilms are colonies of bacterial cells embedded in their self-produced matrix composed of polysaccharides, DNA, and proteins. They protect bacterial cells against antibiotics, antibacterial agents, soaps and detergents, and shear stress. Some of the most common biofilm-associated infections in humans include urinary tract infections, infection of wounds and surgical sites, diabetic foot ulcers, dental caries (tooth decay) and gingivitis (gum inflammation), ventilator-associated infections, sinusitis, microbial keratitis, secondary infection related to Covid-19 and other viral infections, and so on. Bacterial resistance to common antibiotics (e.g., penicillin, gentamycin, erythromycin, ciprofloxacin, etc.) is driving us to a catastrophic failure of our health systems. Strategies to develop novel antibacterial agents and technology must be prioritized to combat and eradicate biofilms and their associated challenges. This book provides a comprehensive overview of biofilms with chapters on bacterial virulence factors, quorum sensing in bacteria, antimicrobial resistance in bacteria, strategies to develop new antibacterial agents, and much more.

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Essential oils for dental health : A holistic guide to oral care and treatment

Explores the benefits of and best methods of use for well-known dental care oils such as peppermint, tea-tree, and clove as well as the lesser known oral benefits of oils like cinnamon, manuka, and oregano. Offers many simple practical techniques to easily incorporate essential oils into your daily oral care routine. Includes recommended oil mixtures targeted to alleviate specific dental and oral ailments, such as periodontitis, oral herpes, ulcers, teething, dry mouth, bad breath, teeth grinding, and toothache.

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Drug-Induced Oral Complications

Provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance.

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Diagnosis of Aging Skin Diseases

Diagnosis of Aging Skin Diseases provides the clinician with an encyclopedia of geriatric dermatoses that can be used on rounds or in a reference environment. It provides a structured illustrated review of the various lesions encountered, which will make this an invaluable reference resource for all physicians dealing with older skin.

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Clinicopathological Correlation of Oral Diseases

Represents an innovative approach to the assessment and diagnosis of both common and relatively uncommon oral diseases. It introduces the reader to adopt a systematic, analytical approach to gather clinical information and understand the underlying pathological processes to arrive at an accurate diagnosis to help efficient management of diseases in the oral and maxillofacial region.

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Managing diabetic wounds : Strategies for effective treatment

Delves into diabetes itself, covering its definition, various types (Type 1, Type 2, and gestational diabetes), and diagnostic laboratory findings such as blood glucose levels and HbA1c. The concept of diabetic foot is thoroughly explored, including its definition, primary causes such as neuropathy, ischemia, and infection, and crucial aspects of prevention, caution, and risk factors like poor glycemic control and smoking.

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Buruli Ulcer : Mycobacterium Ulcerans disease

A major objective of this book is to summarize the current status of Buruli Ulcer (BU) research for the first time. It will identify gaps in our knowledge, stimulate research and support control of the disease by providing insight into approaches for surveillance, diagnosis, and treatment of Buruli Ulcer. Book chapters will cover the history, epidemiology diagnosis, treatment and disease burden of BU and provide insight into the microbiology, genomics, transmission and virulence of Mycobacterium ulcerans.

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Aspirin tablet film coated with famotidine

Focuses on enhancing the gastrointestinal tolerance of aspirin tablets by coating them with famotidine, a histamine-2 receptor antagonist known for its ability to reduce stomach acid production. The project aims to investigate the potential of famotidine coating in mitigating the gastric side effects commonly associated with aspirin usage, such as gastric irritation and ulcers. Through a series of in vitro studies, the project will evaluate the effectiveness of famotidine-coated aspirin tablets in reducing gastric mucosal damage and improving overall gastrointestinal safety.

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Aspirin and omeprazole pellets

The objective of this study was to combine Aspirin and Omeprazole which are often used together in a singular capsule. Aspirin is a common drug for relieving minor aches, pains, and fevers. People also use it as an anti-inflammatory or a blood thinner. Because of its regular and continuous usage, it may cause peptic ulcers. Peptic ulcers are open sores that develop on the inside lining of your stomach and the upper portion of your small intestine which can be uncomfortable and painful. Consequently, people with ulcers resort to omeprazole to treat them...

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Applications of functional foods in disease prevention

Functional food sources are growing in popularity because they are exceptionally nutritious and provide amazing medical advantages. They can help ensure against infection, prevent supplement deficiency, and advance appropriate health development and improvement. With illustrative case studies, this new volume explores the many roles of functional foods in the prevention and management of various diseases, including diabetes, autism spectrum disorder, weight loss and obesity, microbial infections, ulcers and other gastrointestinal diseases, mental disorders and brain health, cardiac health and cardiovascular diseases, osteoporosis and bone health, and more.

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Angiogenesis in Inflammation : Mechanisms and Clinical Correlates

This volume relates the lessons learned from tumour biology applied to inflammation. This issue of Angiogenesis in Inflammation: Mechanisms and Clinical Correlates develops current knowledge on the mechanisms at the molecular and cellular levels as they relate to inflammation, including acute and chronic inflammation, neurogenic initiation, and the role of the multiple cellular components that comprise inflammation: granulocytes, macrophages, fibroblasts, dendritic cells and lymphocytes. This is related to inflammatory disease: not only the familiar angiogenesis dependent diseases of rheumatoid arthritis and psoriasis, but also loci such as the lung, gastric ulcers, the eye with uveitis, wound healing and periodontal disease and their therapy, how this knowledge may be used in the discovery of novel therapeutics. The volume brings together experts in each of these fields to link the molecular and cellular processes in angiogenesis to those of inflammation and disease, culminating in a discourse on areas for future therapies.

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