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نحو فضاء صحي متكامل : مركز السلام الطبي
المركز الطبي هو منشأة صحية متكاملة تتكون من طابقين، صُممت لتقديم خدمات طبية شاملة ضمن بيئة مريحة وعصرية. يتبع تصميمه شكل حرف "U" لتسهيل الحركة وتوزيع الأقسام بشكل واضح. يضم المركز عيادات تخصصية، أقسام تشخيصية (كالأشعة والتحاليل)، مركز علاج فيزيائي، عيادات سنية، وصيدلية، بالإضافة إلى مناطق إدارية واستراحات للزوار. يجمع التصميم بين الأداء الوظيفي والمعايير الجمالية والإنسانية، مع التركيز على الراحة النفسية والإضاءة الطبيعية.
معمل أدوية كيميائية في المدينة الصناعية بعدرا
المشروع عبارة عن مصنع أدوية في مدينة عدرا الصناعية في محافظة ريف دمشق. يتألف المبنى من كتلتين، الكتلة الأولى تضم قبو و هو عبارة عن ملجأ بالإضافة إلى أربعة طوابق فوق الأرض بارتفاع أربعة أمتار، الطابق الأرضي و الثاني عبارة عن مكاتب و جزء منها للتخزين، أما الطابق الأول و الثالث عبارة عن مكاتب إدارة. الكتلة الثانية تضم طابقين فوق الأرض بارتفاع ثمانية أمتار، تستخدم طوابق الكتلة الثانية للتخزين. يقع المشروع ضمن المنطقة الزلزالية الثانية.
Yerba mate is a natural alternative of ozempic
Yerba mate (Ilex paraguariensis), a traditional South American herbal tea, has gained attention as a potential natural alternative to Ozempic (semaglutide), a pharmaceutical drug used for weight management and type 2 diabetes. Rich in bioactive compounds like caffeine, theobromine, chlorogenic acids, and saponins, yerba mate exhibits appetitesuppressing, metabolism-boosting, and glucose-regulating properties. Studies suggest that yerba mate may enhance satiety, promote fat oxidation, and improve insulin sensitivity, mimicking some effects of GLP-1 receptor agonists like Ozempic—but with fewer side effects
X-Ray Contrast Media : Overview, use and pharmaceutical aspects
An overview on CT/X-ray contrast media designed for radiologists and other medical specialists who use contrast media in imaging and interventional procedures as well as related scientists on the use and pharmaceutical aspects of X-ray contrast media. The overall goal of this book is to provide a comprehensive overview relevant for the optimal use of x-ray contrast media covering next to the historic development, their structure and properties also practical information for handling of contrast media, and explanation of the relevant risks during use and measures for prevention and treatment of potential side effects.
Xenobiotic Metabolic Enzymes Bioactivation and Antioxidant Defense
Xenobiotics are commonly referred to as xenobiotics that humans digest or inhale and are not produced by the body, such as foods, drugs, other chemicals, and air pollutants. Metabolic conversion of xenobiotics to facilitate their removal from the body is catalyzed by activation and detoxification enzymes. These enzymes are essential for bioactivation and detoxification of xenobiotics. Many xenobiotics are non-toxic in nature; however, some of them become cytotoxic or carcinogenic after metabolic conversion. Reactive intermediates or metabolites generated during metabolic conversion are generally electrophilic in nature and are either cations or neutral compounds, including reactive oxygen species and free radicals. Metabolic reactive intermediate-mediated oxidative stress can cause damages to cellular components such as impairment of protein functions, membrane lipid peroxidation, and formation of DNA adduct.
Wright's behavior management in dentistry for children ; 3rd ed.
Addresses the influence of family and parenting styles on children’s behavior and the factors that determine how children behave in the dental office. Pharmacological and non-pharmacological management techniques are described in depth, as are techniques for dealing with special needs patients. Clinical case scenarios are described throughout the book, with practical application of the taught principles. The final part of the book covers the dental environment¯training office personnel to manage children’s behavior, practical considerations for behavior guidance, and the effects of the physical dental office environment. A thorough introduction to understanding key moments in child development as well as their behavior in the dental office. An examination of establishing a dental home and non-pharmacologic approaches to behavior management. Treatment of children with disabilities in the dental setting and tips to parents for proper homecare. Understanding the rapidly evolving societal influence on the contemporary family and its impact on treating the pediatric patient. How to deal with the Internet: information, misinformation, and negative online reviews
World Spice Plants : Economic Usage, Botany, Taxonomy
This book addresses the need to disseminate scientific knowledge of the complex world of spice plants to a wide audience of interest. It considers the economic usage of spices in several forms, as an ingredient for adding flavor, as a pot herb and as an additive for condiments such as ketchup, and mustard. The book is aimed primarily at aroma experts in both science and industry, but also botanists, pharmacists, food chemists and dieticians will take inspiration from the book, which is also illustrated by around 100 full color photographs. Comprehensive listing of over 1400 plants / Plant nomenclature from around the world / Arranged alphabetically for ease of reference / Exhaustive register of relevant literature for further reading
Wilson and Gisvold's Textbook of organic medicinal and pharmaceutical chemistry
Serves as the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. This book begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry.
Whole-cell biocatalysis : Next-generation technology for green synthesis of pharmaceutical, chemicals, and biofuels
Is a promising and emerging field of biological science that is mostly based on advancements in biosystems engineering for the production of useful products such as chemicals, fuels, and pharmaceuticals. It is a unique platform that provides an efficient catalytic system at affordable cost and with low maintenance. Recent studies have proven that whole-cell catalysis is very useful in conducting many complex and complicated chemical reactions that could be executed with greater ease and in an eco-friendly manner in ambient conditions with zero/minimal ecological effect. This has made whole-cell biocatalysis very popular and a center of significance in the field of modern biological catalysis.
Water-Insoluble Drug Formulation
Brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development. Twenty-three chapters systematically describe the detailed discussion on solubility theories, solubility prediction models, the aspects of preformulation, biopharmaceutics, pharmacokinetics, regulatory, and discovery support of water-insoluble drugs to various techniques used in developing delivery systems for water-insoluble drugs. This book includes more than 15 water-insoluble drug delivery systems or technologies, illustrated with case studies and featuring oral and parenteral applications. Highlighting the most current information and data available, this seminal volume reflects the significant progress that has been made in nearly all aspects of this field.
Vitreo-retinal Surgery
"This volume on vitreoretinal surgery is written by authors who are leaders in these fields of research. It covers the large body of experimental research performed to date on the most urgent clinical problems of vitreoretinal disease. Topics dealt with in the book include: Methods against etinal Exudation by Thermal Laser / Replacement of the Diseased Retinal Pigment Epithelial (RPE) Cell / Secondary Wound Healing after Retinal Attachment (Proliferative Vitreoretinopathy, PVR) / Adjunct Pharmacotherapy / Heavier than Water Vitreous Substitute / Conditions Associated with a High Risk of PVR (e.g. Giant Tear Retinal Detachments) / Uveitis Vitrectomy with New Diagnostic and Therapeutic Means"
Vitreo-retinal Surgery ; 1st ed.
Progress in vitreo-retinal surgery is mercurial. Since this series is dedicated to new developments the reader is presented with a motley list of topics. The advancements described here may represent generally accepted progress in the field: New instruments, Macular hole surgery, Tumor biopsy. New ideas are set out to be tested for their benefit, for example: AMD surgery, Adjunctive pharmacotherapy. Reflections on incessant clinical problems in vitreo-retina surgery require superior scrutinization of established surgical techniques and indications: Posterior slippage, Inferior breaks, Subclinical retinal detachments. The editors will expand this list in future editions with topics like: new support for buckling surgery, enzyme assisted vitrectomy, new tamponades and other yet unknown fields of progress.
Vitamin C in human health and disease : Effects, mechanisms of action, and new guidance on intake
Presents the scientific evidence on the effects of vitamin C / Clarifies mechanism of action and benefits / Provides new guidance on daily vitamin C intake Presents the scientific evidence for the role of vitamin C in health and disease and offers new guidance on vitamin C intake in humans. The importance of vitamin C in preventing cancer and cardiovascular disease, its relevance to aging and stress, and its impacts on each of the human body systems are thoroughly assessed on the basis of the author’s extensive research and his deep understanding, as an anatomy professor, of the body as a whole. Findings published in the international scientific literature are fully taken into account, and due consideration is also given to empirical evidence, bearing in mind that mechanisms of action cannot always be precisely defined in the absence of human experiments. Beyond providing an up-to-date scientific perspective on the effects of vitamin C, the author hopes to promote human health worldwide by encouraging proper use of the vitamin.
Vitamin A in health and illnesses
Vitamin A is an essential fat-soluble vitamin found in both animal and plant sources. The human body cannot produce Vitamin A on its own, so it must be obtained from the diet, Focuses on vitamin A, its significant role in human health, particularly in skinrelated conditions and pregnancy . The review also discusses the effects of high doses and vitamin A deficiency, with a particular emphasis on its impact during pregnancy and strategies for preventing deficiency symptoms in pregnant women. The therapeutic effects of vitamin A on the skin, including its role in treating acne vulgaris, other skin diseases like psoriasis, are explored. Special attention is given to isotretinoin (Retane), covering its mechanism of action, benefits, and side effects.
Valuation in Life Sciences : A Practical Guide
Recognizes that there is no consent on how to apply valuation methodologies in life sciences. One of the complicating factors is that, compared to other industries, valuation of biotech innovation is much more demanding. The long 10-15-year development and clinical trials process still represents the main risks faced by any biotech company. Added to that is the fact that getting a drug across the regulatory goal line and receiving Food and Drug Administration approval (or other regulatory agency - proval in the United States or elsewhere in the world) for marketing is no longer good enough.
Valuation in Life Sciences : A Practical Guide ; 2nd ed.
Valuation is a hot topic among life sciences professionals. There is no clear understanding on how to use the different valuation approaches and how to determine input parameters. Some do not value at all, arguing that it is not possible to get realistic and objective numbers out of it. Some claim it to be an art. In the following chapters we will provide the user with a concise val- tion manual, providing transparency and practical insight for all dealing with valuation in life sciences: project and portfolio managers, licensing executives, business developers, technology transfer managers, entrep- neurs, investors, and analysts. The purpose of the book is to explain how to apply discounted cash flow and real options valuation to life sciences p- jects, i.e. to license contracts, patents, and firms. We explain the fun- mentals and the pitfalls with case studies so that the reader is capable of performing the valuations on his own and repeat the theory in the exercises and case studies.
Validation in Chemical Measurement
Validation of measurement methods has been used for a very ciated measurement uncertainty? The answer must be: no. long time in chemistry. It is mostly based on the examination There can never be a mechanism or recipe for producing - of a measurement procedure for its characteristics such as tomatically valid results because one can never eliminate precision, accuracy, selectivity, sensitivity, repeatability, re- theskills, the role and the responsibility of the analyst. producibility, detectionlimit, quantification limit and more. ISO 9000:2000, item 3. 8. 5 defines validation as confer- When focussing on quality comparability and reliability mation by examination and provision of objective evidence in chemical measurement.
Vaccines, medicines and COVID-19 : How can WHO be given a stronger voice?
The considerable health, economic and social challenges that the world faced at the beginning of 2020 with COVID-19 continued and worsened in many parts of the world in the second-half of 2020 and into 2021. Many of these countries and nations wanted to explore COVID-19 on their own, sometimes without listening to the main international health bodies such as WHO, an agency of the United Nations system with long-standing experience and vast knowledge at the global level and of which all countries in the world are members.
Utilizing Sumac (Rhus coriaria) in pharmaceutical preparations for skin health
Aims to extract gelatin from sumac berries and incorporate it into two cosmetic products—a lip balm and a facial/hand mask—evaluating their physicochemical properties, antioxidant activity, and skinbenefiting attributes. A secondary objective is to assess the level of awareness among the Syrian population regarding sumac’s various uses beyond its culinary applications. Sumac fruits were mechanically ground and subjected to immersion, ultrasound, and microwave-assisted extraction methods, followed by filtration and evaporation to yield a viscous gelatinous extract.
Une introduction à la médecine traditionnelle chinoise ; Tome 1 : Le corps théorique = An introduction to traditional Chinese medicine ; Vol.1 : The theoretical body
Drawing directly from the primary sources, it illuminates the burgeoning of ideas within the medical community throughout its centuries of history, a development that might give the impression of a seemingly heterogeneous or even confused system of medicine. However, a patient study of the texts in light of the interpretations of the physicians reveals a different picture.
