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Urological Oncology
Urological Oncology provides a comprehensive overview of the multi-disciplinary management of adult genito-urinary (GU) cancers. In a concise, didactic and easy to assimilate format, this book will be helpful for trainee urologists and oncologists. It includes the important principles of evidence-based management of GU cancers to help the reader understand the latest diagnostic and therapeutic modalities. The main emphasis is on clinical presentation, investigations and standard management strategies. An international authorship ensures a consensus approach covering the differing views of various authorities on the subject is provided. The book includes chapters on etiology, pathology including TNM classification, chemotherapy, radiotherapy, indications for surgery and the complications of these treatments.
Updates on Myopia : A clinical perspective
Discusses basic clinical concepts of myopia, prevention of progression and surgical treatments for myopia and pathological myopia. It also summarises the latest evidence and best practices for managing myopia, high myopia and its complications. Written by leading experts, the book addresses clinical diagnosis and interpretation of imaging modalities, and various complications of myopia such as glaucoma, choroidal neovascularization, retinal degeneration and cataracts. It is a valuable comprehensive resource for general and sub-specialist ophthalmologists as well as residents and ophthalmologists in training.
Thyroid Cancer : A Comprehensive Guide to Clinical Management
Paramount to this new edition is a thorough treatment of the nuclear medical aspects of diagnosing and managing the thyroid cancer patient. This includes extensive discussion of isotopes, isotope uptake and scanning procedures, radioiodine ablation and dosimetry (with or without recombinant human TSH), stunning, octreotide and FDG-PET scanning, and various alternative imaging modalities. Additional highlights include management of the scan-negative and thyroglobulin-positive patient, ultrasound of the lymph nodes, local adjuncts to therapy of metastases, low iodine diets and cookbooks, future directions in therapy, and alternative therapies when traditional surgery and radioactive iodine fail.
Thérapeutiques antiangiogéniques en cancérologie = Antiangiogenic therapeutics in oncology
The fundamental role of angiogenesis in tumor growth and spread has been known for over 30 years now. We have recently had effective anti-angiogenic drugs on many tumors. Their use requires a good knowledge of their mode of action, their side effects, their indications and their place in the therapeutic strategy. This work is therefore divided into three points: - It is first recalled the important role of tumor angiogenesis, the means available to evaluate it on histological samples, its practical modalities of use and the side effects of anti-cancer drugs. -angiogenic.- Then the therapeutic results obtained with the anti-VEGF antibodies and the anti-VEGFR tyrosine kinase inhibitors are detailed for each of the tumors.- Finally, the positioning of these new molecules in the multidisciplinary strategy is discussed. - view of other processing methods.
Therapeutic approaches in cancer treatment
A unique blend of structured information covering a broad area relevant to cancer therapeutics.This book comprises fourteen chapters covering cancer genomic approaches for cancer treatment, traditional modalities, chemotherapy, radiotherapy, hormonal therapy, immunotherapy, oncolytic virotherapy, which is another emerging field. Furthermore, it also covers targeted therapies in personalized medicine, which is again an emerging yet promising field for cancer treatment. Use of nanocarriers in the cancer treatment is another important aspect which is a developing thrive. This book is also unique about in covering psychological elements in cancer treatments and providing knowledge for nutritional assessments in cancer treatment. The book has very good text highlighting the important features with a blend of traditional and emerging treatment modalities. Furthermore, chemoresistance development and challenges it poses in cancer treatment along with the pharmacogenetics of anticancer drug, which is way important for the clinicians to understand for their individual patients, associated toxicities, and clinical responses to a particular drug.
The Pathophysiologic Basis of Nuclear Medicine
Deals with molecular imaging. This book includes a separate chapter on the basis of FDG uptake, and offers clinically oriented details on scintigraphic studies, their strengths and limitations in relation to other modalities. It also contains images, illustrations and tables.
The handbook of medicinal chemistry : Principles and practice
Draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies.
Textbook of diabetes
International guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the Textbook hosts an unrivalled blend of clinical and scientific content. Highly-experienced editors from across the globe assemble an outstanding set of international contributors who provide insight on new developments in diabetes care and information on the latest treatment modalities used around the world.
Targeted Cancer Therapy
In the era of personalized medicine, cancer treatment has become a model for the use of targeted therapeutics. Leaving behind the "one size fits all" approach to cancer care, this book provides the practicing oncologist with an overview of the advances in treatment and an understanding of the implementation of new therapeutic agents. Targeted Cancer Therapy is divided into twenty chapters covering specific hematologic malignancies and solid tumors, targeted and functional imaging, and combination therapies. Each disease specific chapter includes up-to-date information on investigational and FDA approved therapies which will enhance the reader’s ability to prescribe effective drug regimens. This includes combinations of therapies and therapeutic modalities to overcome drug resistance.
Surgical Treatment of Hilar and Intrahepatic Cholangiocarcinoma
Cholangiocarcinoma is the second most frequent primary neoplasm of the liver and its incidence is increasing in Western countries. These neoplasms arise from the biliary tract and can be categorized according to their anatomical location as intrahepatic and extrahepatic cholangiocarcinomas. Their prognosis is poor and most patients are unfortunately not suitable for curative resection at the time of diagnosis, due to advanced stage of tumor. However, in recent years, improvement in non invasive diagnostic imaging modalities, preoperative optimisation of liver function, a better understanding of liver anatomy and increased safety of liver surgery had gradually improved outcome
Surgery : Basic Science and Clinical Evidence
Fully revised and updated information on the evidence-based practice of surgery, significant new sections on trauma and critical care on the often challenging surgical care of unique populations; (elderly, pediatric, immunocompromised, and obese patients). The internationally recognized editors and authors have maintained their evidence-based approach throughout the text with thoughtful and timely new chapters on the pre- and post-operative care of the cardiac surgery patient, intestinal transplantation, surgical infections, the fundamentals of cancer genetics and proteomics, and discussions of electrosurgical instruments, robotics, imaging modalities, and other emerging technologies influencing the modern practice of surgery. The oft-cited chapter on the principles of evidence-based decision-making in surgical practice is completely updated for the second edition, presenting the reader with a framework for the evidence-based practice of surgery.
Spinal Imaging : Diagnostic Imaging of the Spine and Spinal Cord
This is a richly illustrated and comprehensive textbook on the imaging of frequently encountered spinal disorders. Degenerative disease, spinal trauma, spinal tumors and the postoperative spine are addressed in detail. In addition, there are individual chapters on embryology, the pediatric spine, biomechanics, scoliosis, bone marrow disorders, infections, spondyloarthropathies and imaging of the sacrum. All imaging modalities are considered, including plain film, multidetector CT and MRI. The book is intended for daily use in any practice that engages in spinal imaging, and will assist both in film interpretation and in image acquisition. Its logical structure and extensive, accurate index are specifically designed to ensure ease of use.
Spatial Cognition VI. Learning, Reasoning, and Talking about Space ; International Conference Spatial Cognition 2008, Freiburg, Germany, September 15-19, 2008. Proceedings
This book includes spatial orientation, spatial navigation, spatial learning, maps and modalities, spatial communication, spatial language, similarity and abstraction, concepts and reference frames, as well as spatial modeling and spatial reasoning.
Space, Movement, and Visibility in Pompeian Houses
Examines the pivotal role of movement, visibility, and experience within Pompeian houses as a major factor determining house form; the use of space; and the manner, meaning, and modalities of domestic daily life, through the application of GIS-based analysis. Through close consideration of ancient literature, detailed explanations of methodology, and exploration of results, Michael Anderson provides new perspectives on Pompeian domestic space including room types and household activities that rarely feature in the discussion of ancient housing. Readers gain a better understanding of priorities in the design of Pompeian houses, the degree to which daily life was interrupted by earthquake damage in the site’s final years, and evolving motivations behind wall painting decoration. The volume not only explores how Pompeian houses reflected the needs of everyday life as imagined by their architects, but also how these spaces served to influence and control daily activities and ultimately how they were transformed by the spatial and visual requirements of domestic life.
Small Bowel Obstruction : CT Features with Plain Film and US correlations
The aim of this book is connect pathophysiology to imaging using many illustrations and examples, emphasizing the capabilities and limitations of multidetector computed tomography and its role in the correct management approach to these disorders. Furthermore, the place of allied imaging modalities (plain film and ultrasound) in the clinical algorithm is comprehensively illustrated.
Small Animal Imaging : Basics and Practical Guide
A practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Skills in Rheumatology
Pesents practical approaches to managing patients affected by various rheumatological diseases, allowing readers to gain a better understanding of the various clinical expressions and problems experienced by these patients. Discussing rheumatology from an organ systems perspective, it highlights the importance of detailed musculoskeletal examinations when treating patients affected by rheumatological diseases. The book first explores the latest diagnostic approaches and offers key tips for accurate musculoskeletal examinations before addressing the various treatment modalities, with a particular focus on the most common joints involved in rheumatoid arthritis: the wrists and the metacarpophalangeal joints (2nd and 3rd)
Representation Learning : Propositionalization and Embeddings
This monograph addresses advances in representation learning, a cutting-edge research area of machine learning. Representation learning refers to modern data transformation techniques that convert data of different modalities and complexity, including texts, graphs, and relations, into compact tabular representations, which effectively capture their semantic properties and relations. The monograph focuses on (i) propositionalization approaches, established in relational learning and inductive logic programming, and (ii) embedding approaches, which have gained popularity with recent advances in deep learning. The authors establish a unifying perspective on representation learning techniques developed in these various areas of modern data science, enabling the reader to understand the common underlying principles and to gain insight using selected examples and sample Python code. The monograph should be of interest to a wide audience, ranging from data scientists, machine learning researchers and students to developers, software engineers and industrial researchers interested in hands-on AI solutions.
Radiologic-Pathologic Correlations from Head to Toe : Understanding the Manifestations of Disease
Offers a comprehensive review of imaging of the whole body based on correlating the radiologic findings with gross and microscopic pathology . Taking advantage of all imaging modalities, the authors give detailed descriptions of radiologic presentations with pathologic correlation, of a broad spectrum of diseases from most organ systems, including the nervous system, head and neck, chest, gastrointestinal and urogenital system, musculoskeletal system and breast. The book helps the clinician to apply the principles of radiologic-pathologic correlation to the interpretation of radiologic studies and therefore to better understand the clinical and pathologic implications of the radiologic appearance. Furthermore this radiologic-pathologic correlation allows to refine the differential diagnosis in key disease entities of the main organ systems. The book is richly illustrated with high-resolution images, many of them in color, and will serve as a unique source of information for radiologists, gastroenterologists, gastrointestinal surgeons, pathologists, gynecologists, urologists and oncologists.
Psychological Approaches to Generalized Anxiety Disorder : A Clinician's Guide to Assessment and Treatment
One of the hallmarks of generalized anxiety disorder, along with diffuse pathological worry and somatic complaints, is its resistance to therapy. Of available treatment modalities for GAD, cognitive-behavioral therapy garners the best empirical support in terms of successful long-term results. Psychological Approaches to Generalized Anxiety Disorder offers clinicians a wide variety of CBT strategies to help clients develop core anxiety-reduction skills, presented so that readers can hone their own clinical skills.
