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One Hundred Years of Chemical Warfare : Research, Deployment, Consequences

On April 22, 1915, the German military released 150 tons of chlorine gas at Ypres, Belgium. Carried by a long-awaited wind, the chlorine cloud passed within a few minutes through the British and French trenches, leaving behind at least 1,000 dead and 4,000 injured. This chemical attack, which amounted to the first use of a weapon of mass destruction, marks a turning point in world history. The preparation as well as the execution of the gas attack was orchestrated by Fritz Haber, the director of the Kaiser Wilhelm Institute for Physical Chemistry and Electrochemistry in Berlin-Dahlem. During World War I, Haber transformed his research institute into a center for the development of chemical weapons (and of the means of protection against them).

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Ondansetron Patches

The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.

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On the path to AI : Law’s prophecies and the conceptual foundations of the machine learning age

This book explores machine learning and its impact on how we make sense of the world. It does so by bringing together two ‘revolutions’ in a surprising analogy: the revolution of machine learning, which has placed computing on the path to artificial intelligence, and the revolution in thinking about the law that was spurred by Oliver Wendell Holmes Jr in the last two decades of the 19th century.

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On the Move to Meaningful Internet Systems : OTM 2008 ; OTM 2008 Confederated International Conferences, CoopIS, DOA, GADA, IS, and ODBASE 2008, Monterrey, Mexico, November 9-14, 2008, Proceedings, Part II

This two-volume set LNCS 5331/5332 constitutes the refereed proceedings of the five confederated international conferences on Cooperative Information Systems (CoopIS 2008), Distributed Objects and Applications (DOA 2008), Grid computing, high performAnce and Distributed Applications (GADA 2008), Information Security (IS 2008), and Ontologies, Databases and Applications of Semantics (ODBASE 2008), held as OTM 2008 in Monterrey, Mexico, in November 2008.

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Ocean Waves Breaking and Marine Aerosol Fluxes

This book presents a comprehensive study on the breaking of surface waves induced by wind and the relationship of breaking rate with marine aerosol fluxes. The book draws attention to the theoretical and experimental achievements in the study of wave breaking phenomena in deep water seas. In particular, it deals with the important problems of energy dissipation and the estimation of energy loss due to wave breaking in deep waters. The rationale behind existing methods and practical outcomes for the estimation of whitecap coverage of the sea surface and energy dissipation rate are given in detail.The book also focuses on the fundamentals of marine aerosols and their generation. The text provides a comprehensive overview of the currently available experimental data on marine aerosol fluxes and presents theoretical methodology of the estimation of the intensity of sea aerosol production. The systematic analysis leads to a novel approach in the development of links between aerosol production with sea state parameters and its seasonal variation in deep water seas.

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Occlusal splints for painful craniomandibular dysfunction

Bridges that gap, presenting a practical guide for the treatment of craniomandibular dysfunction (CMD)—a functional disorder that affects the muscles of mastication, temporomandibular joints, and/or occlusion—in patients with related pain. The first half of the book provides detailed but simple clinical instructions and examples of occlusal splint therapy, including splint fabrication and coordinative training for painful CMD, based entirely on a high level of evidence. The second half delves deeper into the etiology, advanced diagnostic techniques, neurobiology, and pathophysiology of painful CMD and splint therapy.

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Observation of the Earth System from Space

A special highlight is the - termination of seasonal gravity variations caused by changes in continental water masses. For GOCE, to be launched in 2006, new gravity field analysis methods are under development and integrated into the ESA processing s- tem. 200,000 GPS radio occultation pro?les, observed by CHAMP, have been processed on an operational basis. They represent new and excellent inf- mation on atmospheric refractivity, temperature and water vapor. These new developments require geodetic space techniques (such as VLBI, SLR, LLR, GPS) to be combined and synchronized as if being one global instrument.

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Object-Based Image Analysis : Spatial Concepts for Knowledge-Driven Remote Sensing Applications

This book discusses means, technologies and approaches related to the processing and analysis of multi-sensor, multi-resolution data with a focus on the generation, modelling and classification of objects. The applications also address the integration of Geographic Information and the concurrent developments of GIScience and vanquish limitations of pixelwise image processing by exploiting image information context-driven and "intelligently".

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Obesity Management in Family Practice

With guidelines backed by the best scientific data, the book is about application, not just theory. The reader is given the commonsense tools that patients need in order to have ownership of their disease. Ultimately, patients are empowered to control their obesity, resulting in positive interaction between providers and patients.

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Numerical Techniques for Chemical and Biological Engineers Using MATLAB® : A Simple Bifurcation Approach

This book addresses the bifurcation characteristics of chemical and biological processes as the general case and treats systems with a unique steady state as special cases. It uses a system approach which is the most efficient for knowledge organization and transfer. The book develops mathematical models for many commercial processes utilizing the mass-, momentum-, and heat-balance equations coupled to the rates of the processes that take place within the boundaries of the system. The models are solved numerically through MATLAB codes with emphasis on the design and optimization of the chemical and biological industrial equipment and plants.

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Nuel Belnap on Indeterminism and Free Action

Seeks to further the use of formal methods in clarifying one of the central problems of philosophy: that of our free human agency and its place in our indeterministic world. It celebrates the important contributions made in this area by Nuel Belnap, American logician and philosopher. Philosophically, indeterminism and free action can seem far apart, but in Belnap’s work, they are intimately linked. This book explores their philosophical interconnectedness through a selection of original research papers that build forth on Belnap’s logical and philosophical work. Some contributions take the form of critical discussions of Belnap's published work, some develop points made in his publications in new directions, and others provide additional insights on the topics of indeterminism and free action.

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Nuclear Science and Safety in Europe

Recent results on the nature of low-, intermediate- and high-energy nuclear forces as well as on the internal structure of nucleons and atomic nuclei are presented. This book Prospects to find a new state of the nuclear matter at extreme conditions that existed in the early Universe and the utilisation of the nuclear energy are discussed.

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Nuclear fusion research : Understanding plasma-Surface interactions

It became clear in the early days of fusion research that the effects of the containment vessel (erosion of "impurities") degrade the overall fusion plasma performance. Progress in controlled nuclear fusion research over the last decade has led to magnetically confined plasmas that, in turn, are sufficiently powerful to damage the vessel structures over its lifetime. This book reviews current understanding and concepts to deal with this remaining critical design issue for fusion reactors. It reviews both progress and open questions, largely in terms of available and sought-after plasma-surface interaction data and atomic/molecular data related to these "plasma edge" issues.

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Nostalgia and Hope : Intersections between Politics of Culture, Welfare, and Migration in Europe

This book shows how the politics of migration affect community building in the 21st century, drawing on both retrogressive and progressive forms of mobilization. It elaborates theoretically and shows empirically how the two master frames of nostalgia and hope are used in local, national and transnational settings, in and outside conventional forms of doing politics.

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Nonlinear Partial Differential Equations with Applications

This book primarily concerns quasilinear and semilinear elliptic and parabolic partial differential equations, inequalities, and systems. It balances the abstract functional-analysis approach based on nonlinear monotone, pseudomonotone, weakly continuous, or accretive mappings with concrete partial differential equations in their weak (or more general) formulation. Methods of Galerkin or of Rothe are exposed in a large generality. Other methods include various direct methods, regularization, or fixed points. The exposition leads general theory as fast as possible towards the analysis of concrete equations, which have specific applications in continuum (thermo-) mechanics of solids and fluids, electrically (semi-) conductive media, modelling of biological systems, or in mechanical engineering. Selected parts are rather an introduction into the subject while some others form an advanced textbook. The intended audience is graduate and PhD students and researchers in the theory of partial differential equations or in mathematical modelling of distributed parameter systems.

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Nonlinear Oscillations of Hamiltonian PDEs

After introducing the reader to classical finite-dimensional dynamical system theory, including the Weinstein–Moser and Fadell–Rabinowitz resonant center theorems,the author develops the analogous theory for completely resonant nonlinear wave equations. Within this theory, both problems of small divisors and infinite bifurcation phenomena occur, requiring the use of Nash–Moser theory as well as minimax variational methods. These techniques are presented in a self-contained manner together with other basic notions of Hamiltonian PDEs and number theory.

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Nonlinear Dynamics of Structures Under Extreme Transient Loads

Covers model building for different engineering structures and provides detailed presentations of extreme loading conditions. A number of illustrations are given quantifying; a plane crash or explosion induced impact loading, the effects of strong earthquake motion, and the impact and long-duration effects of strong stormy winds—along with a relevant framework for using modern computational tools. The book considers the levels of reserve in existing structures, and ways of reducing the negative impact of high-risk situations by employing sounder design procedures.

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Nonlinear Dynamics and Heterogeneous Interacting Agents

Economic application of nonlinear dynamics, microscopic agent-based modelling, and the use of artificial intelligence techniques as learning devices of boundedly rational actors are among the most exciting interdisciplinary ventures of economic theory over the past decade. This volume provides us with a most fascinating series of examples on "complexity in action" exemplifying the scope and explanatory power of these innovative approaches.

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Nonequilibrium Phenomena in Plasmas

This book presents studies of complexity in the context of nonequilibrium phenomena using theory, modeling, simulations, and experiments, both in the laboratory and in nature.

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No More Muddling Through : Mastering Complex Projects in Engineering and Management

Systems Engineering (SE) is a systematic way of thinking and a methodology to guide demanding problem-solving processes in the fields of management and engineering. This book explains the most important principles and elements of Systems Engineering and three planning cases demonstrate the practical application.

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