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omputational science and its applications - ICCSA 2005 ; Vol. 3480 ; International Conference, Singapore, May 9-12, 2005, Proceedings, Part I
The four volume set assembled following The 2005 International Conference on Computational Science and its Applications, ICCSA 2005, held in Suntec International Convention and Exhibition Centre, Singapore, from 9 May 2005 till 12 May 2005, represents the ?ne collection of 540 refereed papers selected from nearly 2,700 submissions. Computational Science has ?rmly established itself as a vital part of many scienti?c investigations, a?ecting researchers and practitioners in areas ranging from applications such as aerospace and automotive, to emerging technologies such as bioinformatics and nanotechnologies, to core disciplines such as ma- ematics, physics, and chemistry. Due to the shear size of many challenges in computational science, the use of supercomputing, parallel processing, and - phisticated algorithms is inevitable and becomes a part of fundamental t- oretical research as well as endeavors in emerging ?elds.
Ocean Waves Breaking and Marine Aerosol Fluxes
This book presents a comprehensive study on the breaking of surface waves induced by wind and the relationship of breaking rate with marine aerosol fluxes. The book draws attention to the theoretical and experimental achievements in the study of wave breaking phenomena in deep water seas. In particular, it deals with the important problems of energy dissipation and the estimation of energy loss due to wave breaking in deep waters. The rationale behind existing methods and practical outcomes for the estimation of whitecap coverage of the sea surface and energy dissipation rate are given in detail.The book also focuses on the fundamentals of marine aerosols and their generation. The text provides a comprehensive overview of the currently available experimental data on marine aerosol fluxes and presents theoretical methodology of the estimation of the intensity of sea aerosol production. The systematic analysis leads to a novel approach in the development of links between aerosol production with sea state parameters and its seasonal variation in deep water seas.
Observing systems for atmospheric composition : Satellite, aircraft, sensor web and ground-based observational methods and strategies
The new challenge in atmospheric chemistry is to understand the intercontinental transport and transformation of gases and aerosols. This book describes the observational and modeling techniques used to understand the atmospheric composition from satellites, aircraft and ground based platforms. The two common ideas presented throughout are the role of each component in an observing system for atmospheric composition, and the advances necessary to improve the understanding of atmospheric composition. The objective of this book is to provide a larger audience the opportunity to learn about these techniques and advances in atmospheric composition.
Nucleation and Atmospheric Aerosols ; 17th International Conference, Galway, Ireland, 2007
Atmospheric particles are ubiquitous in the atmosphere: they form the seeds for cloud droplets and they form haze layers, blocking out incoming radiation and contributing to a partial cooling of our climate. They also contribute to poor air quality and health impacts. This book brings together the leading experts from the nucleation and atmospheric aerosols research communities to present the current state-of-the-art knowledge in these related fields.
Nuclear fusion research : Understanding plasma-Surface interactions
It became clear in the early days of fusion research that the effects of the containment vessel (erosion of "impurities") degrade the overall fusion plasma performance. Progress in controlled nuclear fusion research over the last decade has led to magnetically confined plasmas that, in turn, are sufficiently powerful to damage the vessel structures over its lifetime. This book reviews current understanding and concepts to deal with this remaining critical design issue for fusion reactors. It reviews both progress and open questions, largely in terms of available and sought-after plasma-surface interaction data and atomic/molecular data related to these "plasma edge" issues.
New Vision of Multiblesclerosis
"There is an evidence that both the multiple sclerosis increased prevalence and incidence rate of over the last few decades. Therefore, the goal of our study is to highlight the causes and the risk factors of such neurological disease in order to raise the public awareness for its early symptoms to be able to treat the patients as early as possible and to have the best outcome. The symptoms of this disease are similar to some extent to other diseases so we will design a table and a test for differential diagnosis with such diseases because there is not a specific diagnostic test also taking into consideration to include in our current project A new promising medication (Radicava)which was first approved by FDA in 2015 in Japan 20 years after all old mentioned medications in this study and we started communication with a brilliant neurological doctor to plan using it first time ever in our country. Beside that we will recommend some important diet to follow for patients and some advises to avoid some risk factors which can develop this disease."
New Results in Numerical and Experimental Fluid Mechanics V ; Contributions to the 14th STAB/DGLR Symposium Bremen, Germany 2004
This volume contains the contributions to the 14. Symposium of the STAB (German Aerospace Aerodynamics Association). The volume gives a broad overview over the ongoing work in this field in Germany, with the topics being high-aspect ratio wings, low aspect-ratio wings, bluff bodies, laminar flow control and transition, active flow control, hypersonic flows, aeroelasticity, aeroacoustics, mathematical fundamentals/ numerical simulation, physical fundamentals, and facilities.
New Frontiers in Lifestyle-Related Diseases
Akiyoshi Hosoyamada, M.D., Ph.D. President, Showa University Tokyo, Japan September 2007 v Preface The leading cause of death in Western countries and some developing countries is atherosclerotic cardiovascular diseases. Among them, acute myocardial infarction is the most common type of fatal disease, caused by the progression of atherosclerosis characterized by accumulation of choles terol in vascular walls. Development of atherosclerosis is greatly enhanced by major risk factors for cardiovascular diseases such as obesity, hyperlip idemia, diabetes (hyperglycemia), and hypertension. Among those, obesity frequently initiates a metabolic change that subsequently induces hyperlip idemia, diabetes, hypertension, and eventually atherosclerotic cardiovascu lar diseases. Because obesity and its related disorders largely depend on lifestyle factors such as high calorie intake and low physical activity, a series of disorders are termed lifestyle-related diseases.
Neuroprotection : Method and protocols
Contains cutting-edge molecular biology methods on neuroprotective mechanisms and specific preclinical models of the CNS injury, iseases and planning translation. Chapters guide readers through neuropathology, neuroprotection, Alzheimer’s disease, amyotrophic lateral sclerosis, ALS, Huntington’s disease , multiple sclerosis, Parkinson’s disease, spinal cord injury, traumatic brain injury, and ischemic brain injury. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Neurodegeneration in Multiple Sclerosis
In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic reliability and to monitor the efficacy of experimental treatment. However, cMRI has limited specificity and accuracy as to the most disabling aspects of the MS pathology, known to occur in and outside macroscopic lesions. Modern quantitative MR techniques have the potential to overcome the limitations of cMRI, and their application is dramatically changing our understanding of how MS causes irreversible disability.
Neurocutaneous Disorders : Phakomatoses and Hamartoneoplastic Syndromes
Neurocutaneous diseases are a wide group of conditions that affect the nervous system but appear as lesions of the skin. Some of the more common entities have variable forms of expression that can confuse the diagnosis; for the rare conditions it is difficult to find descriptions in the literature. Recent insights into their cellular, biochemical and molecular genetic bases have shown the essential need for a new nosology and updated genotype-phenotype correlations. The book provides an authoritative source of knowledge about these difficult problems and bridges the gap between clinical recognition and the new molecular medicine. The editors, distinguished clinicians and geneticists, assembled an internationally renowned group of collaborators, many of them the experts who first described a particular disorder or established its present accepted definition.
Neurochemical Aspects of Excitotoxicity
Leading researchers offer cutting-edge information on glutamate metabolism in the brain, examining the role of glutamate transporters and the involvement of glutamate receptors in the pathogenesis of acute neural trauma and neurodegenerative diseases.
Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity
This comprehensive volume, written by experts in the integrative fields of neuroscience, endocrinology and immunology, provides insight into the mechanisms by which neural and neuroendocrine factors influence susceptibility to infection and autoimmunity. The book focuses on multiple sclerosis as the prototypic autoimmune disease and discusses infectious diseases including anthrax, influenza virus, herpes virus and human immunodeficiency virus. The effects of stress on experimental models of multiple sclerosis and also clinical observations of stress in multiple sclerosis patients are discussed. Neural and Neuroendocrine Mechanisms in Host Defense and Autoimmunity is an ideal book for researches and professionals in the fields of immunology, neuroscience, infectious disease, psychology, microbiology, virology, public health and pharmaceutical sciences.
National Constitutions in European and Global Governance : Democracy, Rights, the Rule of Law: National Reports
It offers important insights into three areas. First, it explores how constitutions reflect the transfer of powers from domestic to European and global institutions. Secondly, it revisits substantive constitutional values, such as the protection of constitutional rights, the rule of law, democratic participation and constitutional review, along with constitutional court judgments that tackle the protection of these rights and values in the transnational context, e.g. with regard to the Data Retention Directive, the European Arrest Warrant, the ESM Treaty, and EU and IMF austerity measures. The responsiveness of the ECJ regarding the above rights and values, along with the standard of protection, is also assessed. Thirdly, challenges in the context of global governance in relation to judicial review, democratic control and accountability are examined. On a broader level, the contributors were also invited to reflect on what has increasingly been described as the erosion or ‘twilight’ of constitutionalism, or a shift to a thin version of the rule of law, democracy and judicial review in the context of Europeanisation and globalisation processes.
Musculoskeletal Sonography : Technique, Anatomy, Semeiotics and Pathological Findings in Rheumatic Diseases
Ultrasonography is effective in the evaluation of joint involvement in patients with rheumatic diseases, and may be useful in diagnosis and in monitoring the synovial inflammation by power Doppler technique, with great sensitivity in comparison with clinical examination. The high-resolution US combined with power Doppler technique is also able to detect the peripheral entheseal abnormality, the bone erosion and the tendon involvement. The purpose of this book is to elucidate the examination technique, the sonographic changes in musculoskeletal rheumatic involvement and the ultrasound assessment of joint rheumatic diseases. The atlas is enriched with several figures, in which the US picture is compared with that of conventional radiography, CT and MRI.
Multiple Sclerosis: Autoimmunity and Management
Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system, destroying the myelin and the axon in variable degrees and producing significant physical disability within 20–25 years in more than 30% of patients. The hallmark of MS is symptomatic episodes that occur months or years apart and affect different anatomic locations. Also, see the Autoimmune Disorders: Making Sense of Nonspecific Symptoms slideshow to help identify several diseases that can cause a variety of nonspecific symptoms. MS is diagnosed on the basis of clinical findings and supporting evidence from ancillary tests. Treatment consists of immunomodulatory therapy for the underlying immune disorder and management of symptoms, as well as nonpharmacologic treatments, such as physical and occupational therapy. Disease-modifying therapies have shown beneficial effects in patients with relapsing MS, including reduced frequency and severity of clinical attacks. These agents appear to slow the progression of disability and the reduce accumulation of lesions within the brain and spinal cord.
MRI Atlas of MS Lesions
MRI has become the main paraclinical test in the diagnosis and management of multiple sclerosis. We have demonstrated more than 400 pictures of different typical and atypical MS lesions in this atlas.
MR Imaging in White Matter Diseases of the Brain and Spinal Cord
Comprises a series of comprehensive and up-to-date reviews on the use of MR imaging in these major neurological conditions. The diverse available MR techniques, such as magnetization transfer MRI, diffusion-weighted MRI, MR spectroscopy, functional MRI, cell-specific MRI, perfusion MRI, and microscopic imaging with ultra-high field MRI, offer an extraordinarily powerful means of gaining fundamental in vivo insights into disease processes. The strengths and weaknesses of all these techniques in the study of multiple sclerosis and other relevant diseases are extensively considered. After an introductory section on neuroimaging technology, subsequent sections address disorders of myelination, demyelinating diseases, immune-mediated disorders, and white matter disorders related to aging and other conditions. This book provides a valuable summary of the state of the art in the field, and defines important areas for future research.
Molecular Mimicry : Infection Inducing Autoimmune Disease
The conceptual basis for molecular mimicry was first defined in the early 1980s when monoclonal antibodies against viruses were also shown to react with non-viral host protein; in this case, measles virus phosphoprotein cross-reacted with host cell cytokeratin, herpes simplex virus type 1 with host-cell vimentin and vaccinia virus with host-cell intermediate filaments. Following this discovery, others emerged, again at the clonal level, that T cell clones against proteins from a variety of infectious agents also reacted with host antigenic determinants. The clonal distinction was imperative fo.
Modern Sports Dentistry
A one-stop reference that will assist primary care community dentists, sports physicians, athletic trainers, and emergency room physicians in meeting the needs of athletes when managing facial and dental trauma and sports-related oral diseases. The opening chapters provide a complete review of sports-related dentoalveolar trauma, with coverage of emergent care, the role of endodontics, surgical issues, and restorative considerations. Prevention of dental trauma by means of mouthguards is then examined, with attention to materials and design, public policy concerning the use of mouthguards, and the role of mouthguards in relation to the ever more pressing issue of concussion in sport. Dental erosion in athletes, for example due to energy drinks, is discussed, as are the possible sequelae of use of spit tobacco, performance-enhancing drugs, and ergogenic aids. The new topic of the potential value of dental appliances in enhancing sports performance is also addressed.
