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Therapeutic approaches in cancer treatment
A unique blend of structured information covering a broad area relevant to cancer therapeutics.This book comprises fourteen chapters covering cancer genomic approaches for cancer treatment, traditional modalities, chemotherapy, radiotherapy, hormonal therapy, immunotherapy, oncolytic virotherapy, which is another emerging field. Furthermore, it also covers targeted therapies in personalized medicine, which is again an emerging yet promising field for cancer treatment. Use of nanocarriers in the cancer treatment is another important aspect which is a developing thrive. This book is also unique about in covering psychological elements in cancer treatments and providing knowledge for nutritional assessments in cancer treatment. The book has very good text highlighting the important features with a blend of traditional and emerging treatment modalities. Furthermore, chemoresistance development and challenges it poses in cancer treatment along with the pharmacogenetics of anticancer drug, which is way important for the clinicians to understand for their individual patients, associated toxicities, and clinical responses to a particular drug.
Targeted Cancer Therapy
In the era of personalized medicine, cancer treatment has become a model for the use of targeted therapeutics. Leaving behind the "one size fits all" approach to cancer care, this book provides the practicing oncologist with an overview of the advances in treatment and an understanding of the implementation of new therapeutic agents. Targeted Cancer Therapy is divided into twenty chapters covering specific hematologic malignancies and solid tumors, targeted and functional imaging, and combination therapies. Each disease specific chapter includes up-to-date information on investigational and FDA approved therapies which will enhance the reader’s ability to prescribe effective drug regimens. This includes combinations of therapies and therapeutic modalities to overcome drug resistance.
Target Cancer Therapy
Cancer is known as abnormal growth of cells due to genetic mutations associated with other factors such as smocking, overweight, physical inactivity and changing reproductive pattern. Each mutation drives a wave of cellular multiplication associated with gradual increases in tumor size, disorganization and malignancy. Cancer treatment are invasive, painful, expensive and often creating long term negative side effect. The most common cancer treatment are chemotherapy, radiation therapy, surgery, hormone therapy, stem cell transplant and the modest one is targeted cancer therapy. Target cancer therapies are drugs or other substances that block the growth and spread of cancer by interfering with specific molecules that are involved in the growth, progression and spread of cancer. Targeted therapies are currently focus of much anticancer drug development, they are cornerstone of precision medicine, a form of medicine that uses information about person’s genes and proteins to prevent, diagnose and treat disease.
Pharmacological applications of hematopoietic growth factors
Hematopoietic growth factors constitute an important group of proteins that predominantly regulate the process of hematopoiesis. Several factors are approved for clinical use in various indications while others are under investigation in the clinic either alone or as combination therapy. The aim of this paper is to review hematopoietic stem cell main growth factors such as erythropoietin, G-CSF, Thrombopoietin, and their medical applications that are approved for human use and intended to treat many diseases.
Molecular Targeting in Oncology
In Molecular Targeting in Oncology, authors present an overview of the development of targeted therapies for the treatment of cancer with an emphasis on clinical application. The volume covers the complexity of the rapidly developing area of targeted therapies for the treatment of patients with cancer and is structured in a way so readers may begin with chapters that most interest them and work through the rest of the chapters in the order of their choice. The volume is divided into five sections that cover the most important elements of drug development. The first section focuses on approaches using targeted therapies to inhibit cell growth. The second section describes how clinicians are evaluating targeted therapies in specific organ systems. The third section illustrates how various classes of pharmacologic and immunologic agents are developed for individual molecular targets. The fourth section details new drugs that have novel mechanisms of action. The final section looks to the future of targeted therapeutics and includes chapters on appropriate patient selection, use of combination therapy, dealing with tumor cell resistance, and more. Comprehensive and cutting-edge, Molecular Targeting in Oncology is an essential reference for those working in the field.
Gentamicin : Biosynthesis, medicinal applications and potential side effects
Discusses the biosynthesis, medicinal applications and potential side effects of Gentamicin. Topics include Gentamicin used in combination therapy and applied to medicinal materials for clinical applications; use of natural products to enhance the antibiotic activity of Gentamicin and other aminoglycosides; regiospecific Gentamicin functionalization; Gentamicin and particle engineering; and the indications and adverse effects of Gentamicin.
Combination therapy against multidrug resistance
Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to understand fully the ways to apply combined therapy to multidrug resistance Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria
