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Viruses in Foods
Cases of viral foodborne outbreaks are on the rise in part due to the increases in population, scarcity of clean water, and changes in eating habits. Outbreaks attributed to toxic, fungal, parasitic, and bacterial agents are very well known and characterized because we have known about these diseases for a long time and have developed appropriate methods to investigate and track them. Detection methods to investigate and track viral agents in food, with the exception of shellfish, have only recently begun to be developed. However, with the advent of molecular diagnostic methods, the role of viruses in foodborne disease outbreaks is beginning to be understood.
Vaccine design : Methods and protocols ; Vol.1 : Vaccines for human diseases
Guides readers through an introductory section on future challenges for vaccinologists and the immunological mechanism of vaccines. Chapters focus on design of human vaccines for viral, bacterial, fungal, and parasitic diseases as well as tumor vaccines. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.
Transgenesis and the Management of Vector-Borne Disease
Parasitic, bacterial and viral agents continue to challenge the welfare of humans, livestock, wild life and plants worldwide. The public health impact and financial consequences of these diseases are particularly hard on the already overburdened economies of developing countries especially in the tropics. Many of these disease agents utilize insect hosts (vectors) to achieve their transmission to mammals. In the past, these diseases were largely controlled by insecticide-based vector reduction strategies. Now, many of these diseases have reemerged in the tropics, recolonizing their previous range, and expanding into new territories previously not considered to be endemic. Habitat change, irrigation practices, atmospheric and climate change, insecticide and drug resistance as well as increases in global tourism, human traffic and commercial activities, have driven the reemergence and spread of vector borne diseases. While these diseases can be controlled through interventions aimed at both their vertebrate and invertebrate hosts, no effective vaccines exist, and only limited therapeutic prospects are available for their control in mammalian hosts. Molecular technologies such as transgenesis, which is the subject of this book, stand to increase the toolbox and benefit disease management strategies.
Topical treatments of skin infection
A hospital-acquired infection, also known as a nosocomial infection, is an infection that is usually transmitted after hospitalization and appears within 48 hours of hospitalization. Bacteria, fungi, and viruses can cause deep infections in healthcare. Bacteria alone cause about 90 percent of these cases, and there are many types of HAI including SSI, which is defined as an infection that occurs up to 30 days after surgery and affects either the incision or the deeper tissues in the operation...
Toll-like Receptors in Inflammation
Toll-like receptors (TLRs) are critical mediators of the innate immune response in mammals. This family of receptors recognizes a variety of microbial products or motifs and initiates the host response to infection. Examples include TLR4 which recognizes lipopolysaccharide (LPS) from Gram-negative bacteria, TLR3 which recognizes viral double-stranded RNA, and TLR9 which recognizes CpG DNA motifs, found in both viruses and bacteria. All TLRs possess an intracellular region termed the Toll-IL-1 receptor-Resistance (TIR) domain which is essential for signaling from these receptors. The specificity of signaling from individual TLRs arises from differential utilization of adapter proteins. This specificity results in a tailoring of the host defense response depending on the microbe being sensed. TLRs are increasingly being implicated in both infectious and inflammatory diseases, notable examples being sepsis, inflammatory bowel disease, atherosclerosis, and asthma. There is, therefore, great interest in targeting TLRs therapeutically since a disruption of TLR function will result in a decrease in the production of inflammatory mediators.
The Spatial Distribution of Microbes in the Environment
This volume highlights recent advances that have contributed to our understanding of spatial patterns and scale issues in microbial ecology, and brings together research conducted at a range of spatial scales (from µm to km) and in a variety of different types of environments.
The silent epidemic
Biofilm is a complex structure of microbiome having bacterial colonies adhere to the surface. These cells are embedded in extracellular polymeric substances, a matrix generally composed of eDNA, proteins and polysaccharides, showing high resistance to antibiotics. Quorum sensing plays an important role in regulating the biofilm formation. Biofilm is one of the major causes of infection persistence especially in nosocomial settings through indwelling devices. There are many approaches being used to control biofilm. Indeed, the adhesive characteristics of natural human flora are now considered as a tool for preventing the adhesion of pathogenic bacteria to avert infection. These antibiofilm approaches represent a promising therapeutic target in the treatment of biofilm infections and development of a strong capability to interfere with different phases of the biofilm development.
The Pangenome: Diversity, Dynamics and Evolution of Genomes
The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded.
The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes
World Health Organization data documents that infectious diseases and immunodeficiencies are the leading causes of morbidity and mortality in the world's children. In The Neurological Manifestations of Pediatric Infectious Diseases and Immunodeficiency Syndromes, an authoritative, international panel of experts provide a succinct, up-to-date, evidence-based reference to the neurological consequences of infectious diseases and immunodeficiency syndromes in children in one readily accessible volume. Within each of its conveniently structured chapters, readers will find a general description of the disease or disorder, its epidemiology, etiology, clinical synopsis, neurological manifestations, diagnosis, differential diagnosis and therapy.
The medical activity of salvadora persica
The human mouth is inhabited from birth by many types and numbers of microbes that are both beneficial and harmful to the health of the mouth and teeth. Either. Multiple factors in the oral environment contribute to the multiplication and diversity of microbes, including in particular the regularity of natural teeth. The cleanliness and maintenance of artificial dentures, the amount of integrity and vitality of gum tissue and ligaments around the age, as well as an important factor relates to food quality. In the mouth, saliva deposits protein-sugar compounds that form thin, transparent layers called pellicle. The surfaces of the teeth (enamels), which helps the oral microbes to adhere to these layers and thus multiply and accumulate in large quantities and in the form of thin organic layers known as microbial dental plaque on the surfaces of the teeth, above and below edge of the gum. It is scientifically proven that if the teeth are not cleaned well or regularly daily and if the accumulation of plaque continues.
The ethanolic extract of Jasmine leaves and its antimicrobial activity
Jasmines are an important group of flowering plants. This genus belongs to the family Oleaceae. Moreover, different parts of the plant such as the leaf, stem, bark, and roots are useful and important in pharmaceutical industries, where their most important property having antimicrobial activities (the aim of this study).
The Biofilm Primer
This book details the widely accepted hypothesis that the majority of bacteria in virtually all ecosystems grow in matrix-enclosed biofilms. The author, who proposed this biofilm hypothesis, uses direct evidence from microscopy and from molecular techniques, presenting cogent reasons for moving beyond conventional culture methods that dominated microbiology throughout the last century. Bacteria grow predominantly in biofilms in all natural, engineered, and pathogenic ecosystems, and this book provides a solid basis for the understanding of bacterial processes in environmental, industrial, agricultural, dental and medical microbiology. Using a unique "ecological" perspective, the author explores the commensal and pathogenic colonization of human organ systems.
The bacterial cell wall : Methods and protocols
Explores methods currently used to investigate the cell wall of various bacterial species and pathogens. By using a combination of genetic, molecular, biochemical, and cytological techniques, the protocols address many fundamental questions involving the composition, biosynthesis, and regulation of bacterial peptidoglycan
The Bacteria : Their Origin, Structure, Function and Antibiosis
This book may seem like three or four books even though the main - cus is on a specialized topic—the bacterial cell wall. Its job is to formulate the innovations that caused life to initiate on earth, those that caused cell physiology to develop without diversity developing, those that allowed the murein walls of the cells to arise, those that led to the separation of the domain of Bacteria from other organisms, those that allowed the Archaea and the Eukarya to develop independently, and those that then led to the development of a very diverse b- sphere.
T cell activation by CD1 and lipid antigens
This volume provides a comprehensive discussion of basic aspects of CD1 biology and summarizes the most recent research into the role of CD1 in infectious, autoimmune, allergic and neoplastic disease.
Systems Biological Approaches in Infectious Diseases
Brings together the various fields of functional genomics and systems biology that provide information on metabolic function with a special emphasis on the identification of drug targets.
Symbiotic association of microorganisms with medicinal and herbal plants
Research establishes that symbiotic association of microbes with medicinal and herbal plants enhance the growth and accumulation of bioactive materials, and that species of microbes including bacterial and fungal species play a key role.
Sulfur Metabolism in Phototrophic Organisms
Provides, for the first time, in-depth and integrated coverage of the functions of sulfur in phototrophic organisms including bacteria, plants and algae; it bridges gaps between biochemistry and cellular biology of sulfur in these organisms, and of biology and environments dominated by them. This book is designed to be a comprehensive resource on sulfur in phototrophic organisms for advanced undergraduate and graduate students, beginning researchers and teachers in the area of photosynthesis, bacterial energy metabolism, biotechnology, plant nutrition, plant production and plant molecular physiology.
Structural and Functional Relationships in Prokaryotes
Aimed at senior level students pursuing a one-semester course in the biology or microbiology curriculum. The text takes a balanced view of prokaryotic physiology, discussing both bioenergetics and bacterial metabolism in a way that establishes general principles and concepts and emphasizes throughout the information gained from model systems. The book also covers some experimental design issues, giving students an appreciation of the practical aspects and consequences of bacterial metabolism. It also stimulates students’ interests in future developments in the field by including discussions by five world-famous bacterial physiologists about future developments in the field.
Sepsis ; 1st ed.
Sepsis is a multi-factorial disease process and this volume provides comprehensive and in-depth reviews of both the basic science and more practical aspects of patient management. These include detailed information on the epidemiology and genetics of sepsis as well as the metabolic and cardiovascular responses to infection. Infectious disease, in relation to sepsis, is well covered including chapters on unusual/exotic infections, control of infection and the rational use of antibiotics. Haematological aspects of sepsis are also reviewed in detail. Further chapters focus on the currently controversial areas of clinical trial design in sepsis and protocol-driven care. A specific chapter, with illustrated cases, draws practical lessons and offers useful management "tips".
