Page 9
Page 9
Molecular Paradigms of Infectious Disease : A Bacterial Perspective
This comprehensive volume, written by leading authors in the field, provides a fundamental understanding of the complex cellular and molecular processes that are important for bacterial virulence and the infectious disease process. Written in a clear and engaging manner, the book highlights key techniques and methodologies that have driven recent discoveries in bacterial pathogenesis, major structures and mechanisms in bacteria that are important for the pathogenesis of these organisms, the regulation of these virulence determinants by global regulators, and bacterial biowarfare agents. Molecular Paradigms of Infectious Disease: A Bacterial Perspective is an ideal book for students, microbiologists, immunologists and scientists and researchers of bacterial pathogenesis.
Molecular Marker Systems in Plant Breeding and Crop Improvement
Successful release of new and better crop varieties increasingly requires genomics and molecular biology. This volume presents basic information on plant molecular marker techniques from marker location up to gene cloning. The text includes a description of technical approaches in genome analysis such as comparison of marker systems, positional cloning, and array techniques in 19 crop plants. A special section focuses on converting this knowledge into general and specific breeding strategies, particularly in relation to biotic stress. Theory and practice of marker assisted selection for QTL, gene pyramiding and the future of MAS are summarized and discussed for maize, wheat, and soybean. Furthermore, approaches in silviculture on the examples of Fagus, Populus, Eucalyptus, Picea and Abies are presented. The volume ends with a comprehensive review of the patents relevant for using molecular markers and marker assisted selection.
Molecular genetics, structures, mechanisms, and functions : Principles of gene manipulation and genomics ; Vol.1
Provides an overview of the future of genetic engineering and delves into the role of biotechnology and its applications in genetic engineering. It discusses the tools of recombinant technology, which have brought about revolution in our understanding of various complex biological phenomena. Chapters cover mutagenesis, construction, and sequencing of DNA libraries along with applications of genetic engineering for improving health, preventing genetic diseases, enhancing food resources, managing environmental bioremediation, and more. Topics include genetic engineering tools for restriction enzymes and vectors, gene and cell division, mutation detection and screening in plants, population genetics, sexuality in bacteria, and more. Several chapters focus on the tools of recombinant technology, such as restriction enzymes, vectors, etc., that have paved the way for creating organisms of choice and opened new horizons in the field of medicine, agriculture, and industry for human welfare.
Molecular Diagnostic PCR Handbook
PREFACE The Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture is involved in agricultural research and development and assists Member States of FAO and IAEA in improving strategies to ensure food security through the use of nuclear techniques and related biotechnologies, where such techniques have a valuable and often unique role. In particular, molecular diagnostic methods have rapidly evolved in the past twenty years, since the advent of the Polymerase Chain Reaction (PCR). They are used in a wide range of agricultural areas such as, improving soil and water management; producing better crop varieties; diagnosing plant and animal diseases; controlling insect pests and improving food quality and safety. The uses of nucleic acid-directed methods have increased significantly in the past five years and have made important contributions to disease control country programmes for improving national and international trade. These developments include the more routine use of PCR as a diagnostic tool in veterinary diagnostic laboratories. However, there are many problems associated with the transfer and particularly, the application of this technology. These include lack of consideration of: the establishment of quality-assured procedures, the required set-up of the laboratory and the proper training of staff. This can lead to a situation where results are not assured. This book gives a comprehensive account of the practical aspects of PCR and strong consideration is given to ensure its optimal use in a laboratory environment. This includes the setting-up of a PCR laboratory; Good Laboratory Practice and standardised of PCR protocols.
Molecular Basis of Thyroid Cancer
Molecular Basis of thyroid Cancer brings together top-flight experts from across the globe to consider present state of the art treatment and techniques and what the future holds. The product of this effort is invaluable to endocrinologists, particularly those with an interest in the thyroid, molecular oncologists, nuclear medicine physicians and those in biotechnology intent on devising innovative therapies for cancer. "Significant advances in our understanding of thyroid cancer have occurred over the previous decade. This text discusses the molecular alterations and pathologic manifestations seen in this disease. Distinguished investigators address both the basic biology and clinical issues pertinent to our understanding and management of patients with thyroid cancer."
Modern aspects of pharmaceutical quality assurance : developing and proposing application models, SOPs, practical audit systems for pharma industry
Aims to develop a tool that will substantially decrease the number of Inspectional Observations and Warning letters, thus eliminating Import Alerts and Consent Decree. This book targets the Pharmaceutical Industry and students of Pharmaceutical Quality Assurance so they can get in hand-ready consolidated information on Pharmaceutical Quality guidelines, Quality metrics, and implementation of simplified SOP guidelines, plant layouts to implement Quality metrics for Pharmaceutical Manufacturing systems in tablets, capsules, liquid orals, and semi-solid dosage forms.
Modelling and Optimization of Biotechnological Processes : Artificial Intelligence Approaches
The book begins with a historical introduction to the field of bioprocess control based on artificial intelligence approaches, followed by two chapters covering the optimization of fed-batch culture using genetic algorithms. Online biomass soft-sensors are constructed in Chapter 4 using recurrent neural networks. The bioprocess is then modelled in Chapter 5 by cascading two soft-sensor neural networks. Optimization and validation of the final product are detailed in Chapters 6 and 7. The general conclusions are drawn in Chapter 8.
Microscopy Techniques
Light Microscopy has returned to fashion through the synergy of green fluorescent protein and a clutch of techniques involving some permutation of lasers, mathematics and acronyms, which offer the prospect of watching biological molecules at work inside living cells. This volume provides an introduction to these techniques … . this volume will be a longer-term reference for anyone who wants to understand how these methods actually work. In this respect it is excellent.
Microorganisms in the deterioration and preservation of cultural heritage
This book offers a comprehensive overview of the role and potential of microorganisms in the degradation and preservation of cultural materials (e.g. stone, metals, graphic documents, textiles, paintings, glass, etc.).
Microfluidics diagnostics : Methods and protocols
Explores a wide range of microfluidic-based approaches that exploit the unique features of microfluidic devices, which hold significant potential in the field of diagnosis. Beginning with a section on microchips for sample preparation, including cell-free DNA, exosomes, and cells, the book continues by covering protein marker analysis and detection, single-cell analysis, analysis of bacteria and viruses, as well as human cell-based culture and analysis. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Microbiomes and emerging applications
Covers a range of important topics and recent advances in metagenomics, microbiomes and their emerging applications, including microbiota transplantation and its health implications. It also discusses microbiome composition and development in humans. The contributors of this volume provide detailed information on prebiotics and probiotics for enhanced human health. They also introduce microbiomes as the next frontiers in medicine, agriculture, industry and environment. A chapter is presented that discusses probiotic research studies in Nigeria and Canada that led to the discovery of Lactobacillus pentosus KCA1. The book contains timely knowledge and will be useful reference material for scientists and researchers working in the fields of food and agricultural biotechnology, biopharmaceuticals and medical biotechnology, fermentation technology, environmental biotechnology, microbiomes and microbial biotechnology and health care.
Microbial Siderophores
"Microbial Siderophores" presents an up-to-date overview of the chemistry, biology and biotechnology of these iron chelators. Following an introduction to the structure, functions and regulation of fungal siderophores, several chapters focus on siderophores of pseudomonads. Here, the technique of siderotyping, which has proved to be a rapid, accurate and inexpensive tool for pseudomonad characterization and identification, is described.
Microbial Processing of Metal Sulfides
The application of microbiological methods to the extraction of metals from minerals has definitely gained a prominent role and is supported by the several bioleaching and biooxidation processes operating in different sites over the world. In recent years new techniques and new results about proteomic and bioinformatics are bringing a new perspective on the microbial processes.This book focuses on the basic aspects of the process with special emphasis on recent contributions regarding the chemical and microbial aspects of the bioleaching process and the use of microorganisms in the treatment of complex ores and concentrates.
Microbial Phosphate Solubilization
Last decade has seen a significantly increased knowledge about phosphate solubilizing microorganisms. Sixty specialists from thirteen countries met in Salamanca to discuss the problems of the high P-unavailability as a soil nutrient for crops, and the hazards of an increasing phosphate input to aquatic habitats from industrial and mining activities, sewage disposal, detergents, and other sources. Updated solutions to enhance P-uptake by plants, bioremediation potential in the rehabilitation of ecosystems, taxonomic characterization interactions with mycorrizae, the physiological and molecular basis of PSM, and possibilities of genetic modifications of rhizospheric microorganisms were among the contributions presented. Challenges in commercializing a phosphate solubilizing microorganism were also outlined by a relevant biotech company.
Microbial bioprocessing of agri-food wastes : food ingredients
Food ingredients are important molecules of the most diverse chemical classes responsible for conferring nutrition, stability, color, flavor, rheological and sensorial characteristics, in addition to several other important uses in the food industry. In this way, the production routes of these ingredients have gained more and more attention from consumers and producing industries, who expect that, in addition to their technological properties, these ingredients are still obtained without synthetic means, with savings of natural resources and mainly with less environmental impact.
Microbes in agri-forestry biotechnology
Explores recent advances on the use of microbes for agri-forestry biotechnological applications. It provides technical concepts and discussions on the use of microorganisms for processes such as bioprocessing, bioremediation, soil enhancement, aquaponics advances, and plant-host symbiosis. The book provides an overview of the microbial approach to the tools and processes used in agriculture and forestry that make or modify products, improve plants for specific uses, and make use of livestock in agricultural systems. The authors discuss the main process conditions that enhance agri-forestry applications with the use of microbes and introduce the use of genetically modified (GM) microbes in agrobiotechnology. Finally, the authors explore the main technological advances in the production of secondary metabolites with potential applications in agri-forestry.
Microalgae Building Enclosures : Design and Engineering Principles
Aims to provide design, engineering, and biotechnical guidelines for microalgae building enclosures that need to be considered for symbiotic relations among the built environment, humans, and ecosystems. Introduces the theoretical background of microalgae as a bioremediator and future energy system and their potential roles toward sustainable and healthy built environments. Part II exemplifies interventions and multiple benefits of microalgae systems in product, architecture, urban, and infrastructure applications across the globe including Africa, Asia, Australia, Europe, South America, and North America. Part III explains the design and engineering criteria, biotechnical design requirements, and various performance metrics for microalgae architecture. Finally, Part IV investigates potential building applications in low-rise buildings, high-rise buildings, and energy-efficient retrofitting. The book also includes international case studies of microalgae building systems within various building types and climates.
Methods and Techniques for Cleaning-up Contaminated Sites
This publication is meant to foster links between groups facing challenges cleaning up contaminated sites through presentations that explore the problems currently being addressed and solutions that are emerging in the field.
Memory B-cells : Methods and protocols
Details in methods to assess memory B cell formation and function in mice and humans. Chapters guide readers through tetramer-based methods to assess antigen-specific memory B cell dynamics in humans and mice in different vaccine, next-generation deep-sequencing, single-cell techniques to assess epigenomic, VDJ landscapes, lymph node aspirates from humans, advanced imaging, murine models to determine memory B cells formation, and bioinformatic techniques and in silico modelling of memory b cell formation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Medicinal plants : From farm to pharmacy
Discuss current research on medicinal plants that connects traditionally accumulated botanical wisdom with current bioprospecting trends and (pre-clinical studies Provide an account of recent research activities on select medicinal plants from various phytogeographical regions all over the world Cater to the interest of a wide range of readers including lay enthusiasts, traditional practitioners as well as research and clinical professionals
