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Stem Cell and Gene-Based Therapy : Frontiers in Regenerative Medicine
Regenerative medicine - stem cell and gene-based therapy - provides a new clinical approach for restoring function of damaged organs and tissues. There has been incredible progress in experimental strategies for tissue regeneration, particularly in cell transplantation and stem cell research. These have led to potential treatment options for many otherwise fatal conditions, including end-stage organ failure. Cell therapy and tissue engineering of viable grafts could therefore provide prospective new solutions to the serious problems of organ donor shortage.
Statistical Monitoring of Clinical Trials : A Unified Approach
Shows that the joint distribution of the test statistics at different analysis times is asymptotically multivariate normal with the correlation structure of Brownian motion (``the B-value") irrespective of the test statistic. The so-called B-value approach to monitoring allows us to use, for different types of trials, the same boundaries and the same simple formula for computing conditional power.
Statistical Learning from a Regression Perspective
Statistical Learning from a Regression Perspective considers statistical learning applications when interest centers on the conditional distribution of the response variable, given a set of predictors, and when it is important to characterize how the predictors are related to the response. As a first approximation, this is can be seen as an extension of nonparametric regression. Among the statistical learning procedures examined are bagging, random forests, boosting, and support vector machines. Response variables may be quantitative or categorical.
Statistical Analysis of Extreme Values : With Applications to Insurance, Finance, Hydrology and Other Fields
Provides a self-contained introduction to the parametric modeling, exploratory analysis and statistical interference for extreme values.The entire text of this third edition has been thoroughly updated and rearranged to meet the new requirements. Additional sections and chapters, elaborated on more than 100 pages, are particularly concerned with topics like dependencies, the conditional analysis and the multivariate modeling of extreme data.
Squeak : Learn Programming with Robots
Squeak: Learn Programming with Robots will teach you core programming concepts based on simple, visual problems that involve manipulation of robots, or "turtles." You will learn basic programming concepts like loops, abstractions, composition, and conditionals. Each chapter is structured so that it can be turned into a one- or two-hour lab session. And while the structured content explains solid principles of object-oriented programming, you'll just have fun going through the sequence of easy examples with the turtle.
Sport and Oral Health : A Concise Guide
Explores the intricate interrelationship between oral health and sport, with the focus on highly popular team games, endurance sports, and explosive events. In order to understand the vulnerability of athletes of all levels of ability to oral health problems, relevant aspects of sports physiology and training are outlined, as are the predisposing behavioral, psychological, and physiological elements. Specific sports-related oral risk factors are identified and detailed, and the dental conditions frequently observed in athletes are explained. The dental clinical reality of athletes reveals a wide spectrum of oral consequences, affecting both soft and hard tissues, that can adversely impact on training and competitiveness. Principles of dental management are highlighted, and therapeutic solutions provided for the most common dental lesions. Emphasis is placed on preventative measures and solutions adapted to the athlete’s individual needs, as well as the importance of effective collaboration with a diverse team of professionals.
Spinal Disorders : Fundamentals of Diagnosis and Treatment
Spinal disorders are among the most common medical conditions with significant impact on health related quality of life, use of health care resources and socio-economic costs. Spinal surgery is still one of the fastest growing areas in clinical medicine. The increasing age of the population will require an increased need for the treatment of degenerative spinal disorders particularly spinal stenosis. Basic knowledge on the state of the art in diagnosis and treatment of spinal disorders is required not only for spine specialists but also for general orthopedic surgeons, rheumatologists, neurologists, psychiatrists, chiropractors, physiotherapists, basic scientists and health care executives to choose and/or evaluate appropriate diagnostic and therapeutic approaches. "Spinal Disorders" is an easily readable teaching tool focusing on fundamentals and basic principles.
Speculative Coolness : Architecture, Media, the Real, and the Virtual
Offers a unique and critical insight into the emergence of a liminal territory that exists between the real and the virtual that mainstream architecture has yet to exploit. Speculative Coolness surveys and collects a highly experimental architecture/design praxis. Presents a selected body of his work, showcasing projects which seek to understand and explore the conditions, contexts, and media logics which govern this new territory, and to speculate on the Architecture[s] which it might occupy, and which might occupy it.
Solving PDEs in Python : The FEniCS Tutorial I
This book offers a concise and gentle introduction to finite element programming in Python based on the popular FEniCS software library. Using a series of examples, including the Poisson equation, the equations of linear elasticity, the incompressible Navier–Stokes equations, and systems of nonlinear advection–diffusion–reaction equations, it guides readers through the essential steps to quickly solving a PDE in FEniCS, such as how to define a finite variational problem, how to set boundary conditions, how to solve linear and nonlinear systems, and how to visualize solutions and structure finite element Python programs.
Solid-State Fermentation Bioreactors : Fundamentals of Design and Operation
Although solid-state fermentation (SSF) has been practiced for many centuries in the preparation of traditional fermented foods, its application to newer products within the framework of modern biotechnology is relatively restricted. It was c- sidered for the production of enzymes in the early 1900s and for the production of penicillin in the 1940s, but interest in SSF waned with the advances in submerged liquid fermentation (SLF) technology. The current dominance of SLF is not s- prising: For the majority of fermentation products, it gives better yields and is e- ier to apply. It is notoriously difficult to control the fermentation conditions in SSF; these difficulties are already apparent at small scale in the laboratory and are exacerbated with increase in scale.
Solidarity in Europe : Citizens' Responses in Times of Crisis
Provides evidence-based knowledge on European solidarity and citizen responses in times of crisis. Does the crisis of European integration translate into a crisis of European solidarity, and if yes, what are the manifestations at the level of individual citizens? How strongly is solidarity rooted at the individual level, both in terms of attitudes and practices? And which driving factors and mechanisms contribute to the reproduction and/or corrosion of solidarity in times of crisis? Using findings from the EU Horizon 2020 funded research project “European paths to transnational solidarity at times of crisis: Conditions, forms, role-models and policy responses” (TransSOL), the books addresses these questions and provides cross-national comparisons of eight European countries – Denmark, France, Germany, Greece, Italy, Poland, Switzerland, and the UK. It will appeal to students, scholars and policymakers interested in the Eurocrisis, politics and sociology.
Solar Cooling Handbook : A Guide to Solar Assisted Cooling and Dehumidification Processes
Provides an overview on the various solutions to convert solar heat into useful cooling, reports about experiences made with realized installations and gives support in the design process. Its use will strongly contribute to achieve high quality solar cooling systems which provide significant energy savings and fulfil the user’s requirements in a safe and reliable way. Handbook for the design of solar assisted air-conditioning systems. With detailed specifications for practitioners
Soft Computing Applications in Industry
Presents several important papers contributed by some of the well-known scientists from all over the globe. The application domains discussed in this book include: agroecology, bioinformatics, branched fluid-transport network layout design, dam scheduling, data analysis and exploration, detection of phishing attacks, distributed terrestrial transportation, fault detection of motors, fault diagnosis of electronic circuits, fault diagnosis of power distribution systems, flood routing, hazard sensing, health care, industrial chemical processes, knowledge management in software development, local multipoint distribution systems, missing data estimation, parameter calibration of rainfall intensity models, parameter identification for systems engineering, petroleum vessel mooring, query answering in P2P systems, real-time strategy games, robot control, satellite heat pipe design, monsoon rainfall forecasting, structural design, tool condition monitoring, vehicle routing, water network design, etc.
Social Competence in Children
Social competence is essential to the mental and physical well-being of all humans, no matter their age. Yet as many as one in ten children has trouble keeping friends or even making friends. In Social Competence in Children, readers will discover a developmental view of social functioning in children at different stages, with an emphasis on clinical conditions that may confound this development. At the outset, the author provides detailed information on theories of social competence and the contexts in which core skills (e.g., appropriate comments, reading verbal cues) are learned. Later chapters address specific challenges to competence and feature case examples illustrating typical patterns of deficits and presenting the latest data on the topic.
Social Cash Transfer in Turkey : Toward Market Citizenship
This book asks whether cash-transfer programs for very low-income households promote social and economic citizenship and, if so, under what conditions. To this end, it brings together elements that are too often considered separately: the transformation of social and economic citizenship rights in a market-centered context, and the increasing popularity of cash transfer as an instrument both of social policy and humanitarian action.
Social and Political Dimensions of Mathematics Education : Current Thinking
Examines the current thinking on five critical social and political areas in mathematics education. It focuses on material conditions in teaching and learning, and details features of social life and their influence on mathematics teaching, learning and achievement.
Smart management : How simple heuristics help leaders make good decisions in an uncertain world
Offers an evidence-based yet practical discussion of how business leaders can use smart heuristics to make good decisions in a VUCA world. building on the fast-and-frugal heuristics program, smart management demonstrates the efficacy of heuristic decision making in a twofold approach. first, it introduces the concept of ecological rationality, which prescribes the environmental conditions under which specific heuristics work well. second, the book describes a repertoire of heuristics, referred to as the adaptive toolbox, that leaders, managers, and professionals can develop and rely on to make a variety of decisions, such as on business strategy, negotiation, and personnel selection.
Smart Buildings Digitalization : IoT and Energy Efficient Smart Buildings Architecture and Applications
Discusses various artificial intelligence and machine learning applications concerning smart buildings. It includes how renewable energy sources are integrated into smart buildings using suitable power electronic devices. The deployment of advanced technologies with monitoring, protection, and energy management features is included, along with a case study on automation. Overall, the focus is on architecture and related applications, such as power distribution, microgrids, photovoltaic systems, and renewable energy aspects. The chapters define smart building concepts and their related benefits.
Smart Buildings Digitalization : Case Studies on Data Centers and Automation
Explains the concept of data centers, including data collection, public parking systems, smart metering, and sanitizer dispensers. Electric urban transport systems and effective electric distribution in smart cities are discussed as well. The extensive role of power electronics in smart building applications, such as electric vehicles, rooftop terracing, and renewable energy integration, is included. Case studies on automation in smart homes and commercial and official buildings are elaborated. This book describes the complete implication of smart buildings via industrial, commercial, and community platforms.
Sleep Neurology : A Comprehensive Guide to Basic and Clinical Aspects
This practical text provides knowledge of the basic neuroscience of sleep and sleep disorders as they interrelate with various neurologic conditions.Chapters in the first section cover neural networks involved in normal sleep processes, including dreams and memory. Also discussed are how these neural networks interact in various sleep stages and sleep disorders, such as sleep related movement disorders. The book's second section explores the pathophysiology of sleep disorders in the spectrum of neurologic conditions in both adults and children. This includes sleep changes in patients with dementia, seizures, headaches, and stroke, and other common neurologic disorders.
