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Metal Catalysed Reactions in Ionic Liquids
Metal Catalysed Reactions in Ionic Liquids is the first non-edited book on the subject of metal catalysed reactions in ionic liquids and covers the literature from its origins until early 2005.The book begins with a general introduction to the field of biphasic/multiphasic catalysis and describes the synthesis, functionalisation and fundamental properties of ionic liquids relevant to catalysis.This book is an invaluable resource for all those working in catalysis, green chemistry, and advanced synthetic methods,
Messenger RNA therapeutics
Focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine.
Meshless Methods in Solid Mechanics
The main objective of this book is to provide a textbook for graduate courses on the computational analysis of continuum and solid mechanics based on meshless (also known as mesh free) methods. It can also be used as a reference book for engineers and scientists who are exploring the physical world through computer simulations. Emphasis of this book is given to the understanding of the physical and mathematical characteristics of the procedures of computational solid mechanics. It naturally brings the essence, advantages and challenging problems of meshless methods into the picture. The subjects in this book cover the fundamentals of continuum mechanics, the integral formulation methods of continuum problems, the basic concepts of finite element methods, and the methodologies, formulations, procedures, and applications of various meshless methods. It also provides general and detailed procedures of meshless analysis on elastostatics, elastodynamics, non-local continuum mechanics and plasticity with a large number of numerical examples. Some basic and important mathematical methods are included in the Appendixes. For the readers who want to gain knowledge through hands-on experience, the meshless programs for elastostatics and elastodynamics are also introduced in the book and included in the disc.
Meeting Basic Learning Needs in the Informal Sector : Integrating Education and Training for Decent Work, Empowerment and Citizenship
This anthology brings together basic facts and features about basic learning needs and skills of people working and living in the informal economy and presents case studies from different countries examining educational and training strategies for meeting these learning needs. It portrays the grave problems facing educational and training systems vis-á-vis informal sector workers, even as they look at holistic solutions that take into account principles of lifelong learning and innovations in informal, non-formal and formal adult learning, and show a growing awareness that education is a human right of fundamental significance to promoting decent work and humane living conditions.
Medicinal Chemistry for Practitioners
Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.
Medicina fisica e riabilitativa nei disturbi di equilibrio = Physical and rehabilitative medicine in balance disorders
Balance disorders are very common in the population: particularly frequent over the age of 40, are the first motivation for a medical examination after the age of 65 and frequently tend to become chronic. Balance disorders are symptoms of system dysfunction vestibular, complex sensory-psycho-motor system, whose task is that to control the activity of the antigravity muscles to maintain the erect station, of the oculomotor ones to allow the stabilization of the visual field during movement, and the neurovegetative functions they have relationship with standing and movement. Whether the vestibular system provides the information necessary for the check-up of the erect position, the rachis realizes it through a "stability dynamic ", allowed by its structural characteristics proprioception the spine is also a fundamental sensor for controlling balance ; therefore the techniques of physical and rehabilitative medicine and of manual medicine represent a powerful tool for curing ailments equilibrium. This volume comes from the comparison between a physiatrist and an audiologist, who for 15 years have integrated their clinical experience and therefore proposes a new one inter-specialist approach to the diagnostic and therapeutic problems of patients with balance disorders.
Mechatronic Systems : Fundamentals
Mechatronic Systems introduces these developments by considering the dynamic modelling of components together with their interactions. The whole range of elements is presented from actuators, through different kinds of processes, to sensors.
Mechanics of Civil Engineering Structures
Presents the material needed by practicing engineers engaged in the design of civil engineering structures, and students of civil engineering. The book covers the fundamental principles of mechanics needed to understand the responses of structures to different types of load and provides the analytical and empirical tools for design. The title presents the mechanics of relevant structural elements—including columns, beams, frames, plates and shells—and the use of mechanical models for assessing design code application. Eleven chapters cover topics including stresses and strains; elastic beams and columns; inelastic and composite beams and columns; temperature and other kinematic loads; energy principles; stability and second-order effects for beams and columns; basics of vibration; indeterminate elastic-plastic structures; plates and shells.
Mechanics of biomaterials : Fundamental principles for implant design
Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues.
Mechanics and Physics of Fracture : Multiscale Modeling of the Failure Behavior of Solids
Provides a comprehensive understanding of the macroscopic failure behavior of solids from the description of the microscopic failure processes and their coupling with the microstructure. Several fundamental questions were addressed: the relation between the microstructural features of materials and their fracture properties and crack trajectories; the role of damage mechanisms and non-linear deformations near the crack tip on the failure behavior of solids; and finally the role of dynamic inertial effects during fast fracture was more briefly evoked.
Mechanical System Dynamics
This textbook gives a clear and thorough presentation of the fundamental principles of mechanical systems and their dynamics. It provides both the theory and applications of mechanical systems in an intermediate theoretical level, ranging from the basic concepts of mechanics, constraint and multibody systems over dynamics of hydraulic systems and power transmission systems to machine dynamics and robotics.
Mechanical Behavior of Materials : Fundamentals, Analysis, and Calculations
Provides a holistic understanding of mechanical behavior of materials, and enables critical thinking through mathematical modeling and problem solving.Each of the 15 chapters first introduces readers to the technologic importance of the topic and provides basic concepts with diagrammatic illustrations; and then its engineering analysis/mathematical modelling along with calculations are presented.
Measurement Errors and Uncertainties : Theory and Practice
Measurement Errors and Uncertainties addresses the most important problems that physicists and engineers encounter when estimating errors and uncertainty. Building from the fundamentals of measurement theory, the author develops the theory of accuracy of measurements and offers a wealth of practical recommendations and examples of applications.
Measure, Integration & Real Analysis
This book welcomes students into the fundamental theory of measure, integration, and real analysis. Focusing on an accessible approach, Axler lays the foundations for further study by promoting a deep understanding of key results.
Measure Theory and Probability Theory
The book can be used as a text for a two semester sequence of courses in measure theory and probability theory, with an option to include supplemental material on stochastic processes and special topics.Prerequisites are kept to the minimal level of an understanding of basic real analysis concepts such as limits, continuity, differentiability, Riemann integration, and convergence of sequences and series. A review of this material is included in the appendix. The book starts with an informal introduction that provides some heuristics into the abstract concepts of measure and integration theory, which are then rigorously developed. The first part of the book can be used for a standard real analysis course for both mathematics and statistics Ph.D. students as it provides full coverage of topics such as the construction of Lebesgue-Stieltjes measures on real line and Euclidean spaces, the basic convergence theorems, L^p spaces, signed measures, Radon-Nikodym theorem, Lebesgue's decomposition theorem and the fundamental theorem of Lebesgue integration on R, product spaces and product measures, and Fubini-Tonelli theorems. It also provides an elementary introduction to Banach and Hilbert spaces, convolutions, Fourier series and Fourier and Plancherel transforms.
Matrix Algebra From a Statistician`s Perspective
This book presents matrix algebra in a way that is well-suited for those with an interest in statistics or a related discipline. It provides thorough and unified coverage of the fundamental concepts along with the specialized topics encountered in areas of statistics such as linear statistical models and multivariate analysis. It includes a number of very useful results that have only been available from relatively obscure sources. Detailed proofs are provided for all results. The style and level of presentation are designed to make the contents accessible to a broad audience. The book is essentially self-contained, though it is best-suited for a reader who has had some previous exposure to matrices (of the kind that might be acquired in a beginning course on linear or matrix algebra).
Matrix Algebra : Theory, Computations, and Applications in Statistics
Matrix algebra is one of the most important areas of mathematics for data analysis and for statistical theory. The first part of this book presents the relevant aspects of the theory of matrix algebra for applications in statistics. This part begins with the fundamental concepts of vectors and vector spaces, next covers the basic algebraic properties of matrices, then describes the analytic properties of vectors and matrices in the multivariate calculus, and finally discusses operations on matrices in solutions of linear systems and in eigenanalysis. This part is essentially self-contained.
Mathématiques de base pour économistes = Basic Mathematics for Economists
This book contains fundamental elements of mathematics and includes the following elements: notion of logic, propositions, theorems, sets, relations and functions; graphical representations of functions, economic applications of lines and functions, sequences, limits and first derivative, differential economic applications of derivatives; integrals: undefined and defined with economic applications; mathematical series; functions of several variables, partial derivatives, Lagrange multiplier with economic applications; linear algebra: matrix calculus, system of linear equations, vectors, differential calculus in matrix form.
Mathematics of Large Eddy Simulation of Turbulent Flows
Large eddy simulation (LES) is a method of scientific computation seeking to predict the dynamics of organized structures in turbulent flows by approximating local, spatial averages of the flow. This book focuses on the mathematical foundations of LES and its models and provides a connection between the powerful tools of applied mathematics, partial differential equations and LES. Thus, it is concerned with fundamental aspects not treated so deeply in the other books in the field, aspects such as well-posedness of the models, their energy balance and the connection to the Leray theory of weak solutions of the Navier-Stokes equations.
Mathematics and the Aesthetic : New Approaches to an Ancient Affinity
The essays in this book explore the ancient affinity between the mathematical and the aesthetic, focusing on the fundamental connections between these two modes of reasoning and communicating. From historical, philosophical and psychological perspectives, with particular attention to certain mathematical areas such as geometry and analysis, the authors examine the ways in which the aesthetic is ever present in mathematical thinking and contributes to the growth and value of mathematical knowledge.
