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Dry Mouth : A Clinical Guide on Causes, Effects and Treatments
This wide-ranging guide to dry mouth, or xerostomia, is intended to meet the needs of dentists by providing information on all clinically relevant aspects. After introductory discussion of salivary secretion and function, the potential causes of dry mouth, including diseases affecting saliva production, drugs and irradiation, are examined.
Drug-Induced Oral Complications
Provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance.
Drug Selectivity : An Evolving Concept in Medicinal Chemistry
Provides a current overview and comprehensive compilation for medicinal chemists that discusses the effects of aiming for multiple targets on the entire drug development process. The result is a broad survey of current and future strategies for drug selectivity in medicinal chemistry with theoretical but also practical aspects. Different strategies are presented and evaluated, such as various design approaches, merged multiple ligands, discovery technologies and a broad range of successful examples of unselective drugs taken from all major disease areas. With its wide-ranging view of an emerging new paradigm in drug development, this handbook is of prime importance for every medicinal and pharmaceutical chemist.
Drug Metabolism: Current Concepts
The user-friendly text focuses on concepts rather than extraneous details and is supported by many illustrated examples of biotransformations as well as frequent references to current critical reviews and articles highlighting the nature of research objectives in this vibrant area of medicinal development.
Drug delivery trends ; Vol. 3 : Expectations and realities of multifunctional drug delivery systems
Examines a drift in the pharmaceutical field across the wide range of dosage forms, drug delivery systems (micro and nanoparticulate), at the regulatory front and on new types of therapies in the market. This book covers the challenges on drug delivery systems in terms of preclinical and current ways of determining quality and the options to solve the challenges associated with this. Most small-medium scale industries and academics struggle with initial regulatory challenges so a detailed discussion on regulatory trend covers the necessary basic understanding of regulatory procedures and provides the required guidance.
Drug and Biological Development : From Molecule to Product and Beyond
Drug and Biological Development: From Molecule to Product and Beyond offers a complete discussion of product development in the pharmaceutical and biotechnology industries from discovery to product launch, continuing through life cycle management. The book is organized for optimal usefulness in the education and training of health care professionals. The text's narrative descriptions are enhanced by real-life examples, illustrations, controversies in industry, and references. Dr. Ronald Evens and his contributors are industry and research experts in a variety of disciplines.
Drawing imagining building : Embodiment in architectural design practices
Drawing Imagining Building focuses on the history of hand-drawing practices to capture some of the most crucial and overlooked parts of the process. Using 80 black and white images to illustrate the examples, it examines architectural drawing practices to elucidate the ways drawing advances the architect’s imagination.
Drawing for Interior Design ; 2nd ed.
Covers all stages of visual presentation as part of the interior design process, from the most basic initial sketches to fully developed computer-generated visualizations. Following a brief introduction four chapters take the reader through the design process, from the basics to conception, presentation and production. This second edition includes more practical advice on techniques, more case studies, step-by-step sequences and updated examples. With a varied and comprehensive range of images, this book is an invaluable, inspirational and practical resource for interior design students.
Drawing Climate : Visualising Invisible Elements of Architecture
Investigates the history, theory and applications of climatic design in the built environment examining architecture and landscapes from various time periods. Based on a collaboration between the University of Sydney and the National University of Singapore, the book brings together contributing authors from Australia, Singapore, and the United States.
Drawing architecture and the Urban
Provides an instrumental approach to drawing, especially computer-generated drawings; it outlines how drawings should be used to convey clear and analytical information in the process of design, as well as the communication and discussion of a project. In depth examples are provided how to communicate effectively. The final section demonstrates how to transform case-studies, directly connecting an analytical approach with the design process.
Double-stranded RNA : Methods and protocols
Examines classical and cutting-edge methods involving double-stranded RNA (dsRNA), specifically regarding isolation, visualization, characterization, production, and application. Many protocols, such as co-immunoprecipitation-based isolation of double-stranded RNA-associated protein complexes, identification of mycoviruses by dsRNA extraction, application of dsRNA for fungi disease management (Sclerotinia sclerotiorum and Botrytis cin), and production of double-stranded RNA in plants by plant viral vectors for gene silencing, can also be easily adapted for identification of viruses from other organisms, control of other pathogens, and fundamental research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips for troubleshooting and avoiding known pitfalls.
Doppler Ultrasound in Obstetrics and Gynecology
Doppler Ultrasound in Obstetrics & Gynecology encompasses the full spectrum of clinical applications of Doppler ultrasound for the practicing obstetrician-gynecologist, including the latest advances in 3D and color Doppler and the newest techniques in 4D fetal echocardiography. Written by preeminent experts in the field, the book covers the basic and physical principles of Doppler ultrasound; the use of Doppler for fetal examination, including fetal cerebral circulation; Doppler echocardiography of the fetal heart; and the use of Doppler for postdated pregnancy and in cases of multiple gestation. Chapters on the use of Doppler for gynecologic investigation include ultrasound in ectopic pregnancy, for infertility, for benign disorders and for gynecologic malignancies.
Don’t Panic with Mechanics! : Fun and success in the "loser discipline" of engineering studies!
The ultimate companion in the classical horror discipline of engineering science! Contents of the book are the basics of mechanics as treated in engineering and physical sciences: Statics, Elastostatics, Kinematics & Kinetics in unconventional, humorous presentation with many cartoons, funny explanations and a chapter containing several exercises with detailed solutions.
DOM Scripting : Web Design with JavaScript and the Document Object Model
There are three main technologies married together to create usable, standards-compliant web designs: XHTML for data structure, Cascading Style Sheets for styling your data, and JavaScript for adding dynamic effects and manipulating structure on the fly using the Document Object Model. This book is about the latter of the three. DOM Scripting: Web Design with JavaScript and the Document Object Model gives you everything you need to start using JavaScript and the Document Object Model to enhance your web pages with client-side dynamic effects. Jeremy Keith starts off by giving you a basic crash course in JavaScript and the DOM, then moves on to provide you with several real-world examples built up from scratch, including dynamic image galleries and dynamic menus. Then, he shows you how to manipulate web page style using the CSS DOM, and create markup on the fly.
Doing integrated history and philosophy of science : A case study of the origin of genetics
offers an integrated historical and philosophical examination of the origin of genetics. The author contends that an integrated HPS analysis helps us to have a better understanding of the history of genetics, and sheds light on some general issues in the philosophy of science. consists of three parts. It begins with historical problems, revisiting the significance of the work of Mendel, de Vries, and Weldon. Then it turns to integrated HPS problems, developing an exemplar-based analysis of the development and the progress in early genetics. Finally, it discusses philosophical problems: conceptual change, evidence, and theory choice.
Distributed network systems : From concepts to implementations
This textbook covers both theoretical and practical aspects of distributed computing. It describes the client-server model for developing distributed network systems, the communication paradigms used in a distributed network system, and the principles of reliability and security in the design of distributed network systems. Based on theoretical introductions, the book presents various implementation strategies and techniques for building distributed network systems, including examples in TCP/IP communications, the use of remote procedure call and remote method invocation techniques, and the development of web-based applications, distributed databases, and mobile computing systems.
Dissipative Systems Analysis and Control : Theory and Applications
Dissipative Systems Analysis and Control (second edition) presents a fully revised and expanded treatment of dissipative systems theory, constituting a self-contained, advanced introduction for graduate students, researchers and practising engineers. It examines linear and nonlinear systems with examples of both in each chapter; some infinite-dimensional examples are also included. Throughout, emphasis is placed on the use of the dissipative properties of a system for the design of stable feedback control laws. The theory is substantiated by experimental results and by reference to its application in illustrative physical cases (Lagrangian and Hamiltonian systems and passivity-based and adaptive controllers are covered thoroughly).
Dissipative Solitons : From Optics to Biology and Medicine
The dissipative soliton concept is a fundamental extension of the concept of solitons in conservative and integrable systems. It includes ideas from three major sources, namely standard soliton theory developed since the 1960s, nonlinear dynamics theory, and Prigogine's ideas of systems far from equilibrium. These three sources also correspond to the three component parts of this novel paradigm. This book explains the above principles in detail and gives the reader various examples from optics, biology and medicine. These include laser systems, optical transmission lines, cortical networks, models of muscle contraction, localized vegetation structures and waves in brain tissues.
Dissipative Solitons
This volume is devoted to the exciting topic of dissipative solitons, i.e. pulses or spatially localised waves in systems exhibiting gain and loss. Examples are laser systems, nonlinear resonators and optical transmission lines. The physical principles and mathematical concepts are explained in a clear and concise way, suitable for students and young researchers. The similarities and differences in the notion of a soliton between dissipative systems and Hamiltonian and integrable systems are discussed, and many examples are given. The contributions are written by the world's leading experts in the field, making it a unique exposition of this emerging topic.
Dissecting Discrimination : Identifying Its Various Faces and Their Sources
This book examines the phenomenon of discrimination using a descriptive approach. Discrimination is omnipresent, whether it is people who discriminate against other people or, more recently, also machines that discriminate against people. The first part of the analysis employs decision theory on discrimination, leading to two fundamental subtypes: taste-based discrimination and statistical discrimination. The second part links taste-based discrimination to social identity theory, demonstrates that not all taste-based discrimination is ultimately statistical discrimination, and reveals the evolutionary origins of our tastes.
