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Polymer Therapeutics I : Polymers as Drugs, Conjugates and Gene Delivery Systems
As the 21st century begins we are witnessing a paradigm shift in medical prac-tice. Whereas the use of polymers in biomedical materials applications – for example, asprostheses, medical devices, contact lenses, dental materials and pharmaceutical excipi-ents – is long established, polymer-based medicines have only recently entered routineclinical practice . Importantly, many of the innovative polymer-based therapeu-tics once dismissed as interesting but impractical scientific curiosities have now shownthat they can satisfy the stringent requirements of industrial development and regula-tory authority approval.
Polymer Surfaces and Interfaces : Characterization, Modification and Applications
Surfaces and interfaces of polymers play an important role in most of the application areas of polymers. In Polymer Surfaces and Interfaces, experts provide concise explanations, with examples and illustrations, of the key techniques.
Political Economies of Landscape Change : Places of Integrative Power
Examines the complex relationships between political economy and landscape change. It encompasses perspectives ranging from radical landscape interpretation to sustainable livelihoods, real estate economics, institutions, international landscape policies, and global finance. It asks what difference "design", can make within the broader structural contexts of landscape change. The perspectives in this book share a common concern for what economist and futurist Kenneth Boulding termed "integrative power" – the power of human solidarity, respect, and love – to direct political and economic change toward paths of sustainable landscape design.
Police policy shifts after 9/11 : From community policing to homeland security : A New York case study
Addresses the impact of the September 11th terror attacks on funded programs in policing. Comparing New York City's policing, community policing, and homeland security programs, this brief examines twenty-four years of federal grants to identify shifts in policy. Using focusing events and moral panic theories, it posits that 9/11 served as a catalyst to change public policy, moving policing programs in the direction of homeland security. With a before-after-study design, this volume empirically assesses policy shifts to better understand the influence of events and of funding on policing models.
Polarization and Moment Tensors : With Applications to Inverse Problems and Effective Medium Theory
Presents important recent developments in mathematical and computational methods used in impedance imaging and the theory of composite materials. The methods involved come from various areas of pure and applied mathematics, such as potential theory, PDEs, complex analysis, and numerical methods. The unifying thread in this book is the use of generalized polarization and moment tensors.The main approach is based on modern layer potential techniques. By augmenting the theory with interesting practical examples and numerical illustrations.
Points fixes, zéros et la méthode de Newton = Fixed points, zeros and Newton's method
This work is devoted to the fixed points of differentiable applications, to the zeros of non-linear systems and to Newton's method. It is aimed at masters students or preparing for the aggregation of mathematics and confirmed researchers. The first part is devoted to the method of successive approximations and confronts a “dynamical systems” point of view (Grobman-Hartman theorems, of the stable manifold) with examples resulting from numerical analysis. The second part of this work presents Newton's method and its most recent developments (Smale's alpha theory, under- or over-determined systems). It presents a new approach to this subject and a set of original results published for the first time in a French-language work. This is an advanced text on fixed points, zeros of nonlinear systems and the Newton method. Its first part, devoted to fixed points, includes the Grobman-Hartman and the stable manifold theorems. The second part describes the Newton method from a modern point of view: Smale's alpha theory, underdetermined and overdetermined systems of equations. These results are illustrated by various examples from numerical analysis.
Point Process Theory and Applications : Marked Point and Piecewise Deterministic Processes
Offers a mathematically rigorous exposition of the basic theory of marked point processes developing randomly over time, and shows how this theory may be used to treat piecewise deterministic stochastic processes in continuous time. The focus is on point processes that generate only finitely many points in finite time intervals, resulting in piecewise deterministic processes with "few jumps". The point processes are constructed from scratch with detailed proofs and their distributions characterized using compensating measures and martingale structures. Piecewise deterministic processes are defined and identified with certain marked point processes, which are then used in particular to construct and study a large class of piecewise deterministic Markov processes, whether time homogeneous or not. The second part of the book addresses applications of the just developed theory. This analysis of various models in applied statistics and probability includes examples and exercises in survival analysis, branching processes, ruin probabilities, sports (soccer), finance and risk management (arbitrage and portfolio trading strategies), and queueing theory.
Pocket Guide to Musculoskeletal Diagnosis
The author offers clear explanations why each step in the history and physical examination is performed and discusses the basic pathophysiological processes involved. The ailments covered include neck and shooting arm pain; shoulder pain; elbow pain; wrist and hand pain; low back, hip, and shooting leg pain; knee pain; ankle pain; and foot pain. Numerous high-quality photographs illustrate the correct hands-on methods for physical examination of the patient. Comprehensive yet concise, the Pocket Guide to Musculoskeletal Diagnosis offers all orthopedists, physiatrists, family physicians, internists, and physical therapists a step-by-step approach to taking a history and performing a targeted physical examination for musculoskeletal problems, as well as their confident management.
PMP project management professional study guide
Providing complete coverage of all official objectives for the PMP exam; this book includes an Exam Readiness checklist; Inside the Exam sections in every chapter; Two-Minute Drills; and simulated exam questions that match the format; tone; topics; and difficulty of the real exam.
Play-Responsive Teaching in Early Childhood Education
Develops a theoretical concept of teaching that is relevant to early childhood education, and based on children’s learning and development through play. It discusses theoretical premises and research on playing and learning, and proposes the development of play-responsive didaktik. It examines the processes and products of learning and development, teaching and its phylogenetic and ontogenetic development, as well as the ‘what’ of learning and didaktik. Next, it explores the actions, objects and meaning of play and provides insight into the diversity of beliefs about the practices of play. The book presents ideas on how combined research and development projects can be carried out, providing incentive and a model for practice development and research. The second part of the book consists of empirical studies on teacher’s playing skills and examples of play with very young as well as older children.
Player creation system (PCS)
Human simulation in a virtual environment has been the focus of many studies in recent years. Achieving such a task would open up limitless possibilities, it can, for example, benefit many aspects of life such as educational and medical purposes. This project aims to train Artificial Intelligence (AI) models to accurately synthesize a human’s voice, reconstruct their body and facial features as well as teaching an AI agent how to walk. This report documents the aspects. regarding the voice cloning aspect, our goal is to synthesize human’s voice using a short audio recording of that human, which is achieved through a pipeline consisting of three neural networks, voice encoder neural network, synthesis neural network, vocoder neural network.
Play and Learning in Early Childhood Settings : International Perspectives
Provides the first ever cultural-historical study of the play of children from birth to 2 years of age in their early childhood education and care settings across 7 countries. Researchers from New Zealand, Australia, Chile, Hong Kong China, Japan, Sweden and USA present their investigations of the play activities of infants and toddlers in their early childhood settings. They examine the cultural construction of play in these different contexts through a cultural-historical analysis.
Plastics for Corrosion Inhibition
The development of polymer composites containing inhibitors of metal corrosion is an important endeavour in modern materials science and technology. Corrosion inhibitors can be located in a polymer matrix in the solid, liquid or gaseous phase. This book details the thermodynamic principles for selecting these components, their compatibility and their effectiveness. The various mechanisms of metal protection – barrier, inhibiting and electromechanical – are considered, as are the conflicting requirements placed on the structure of the combined material. Two main classes of inhibited materials (structural and films/coatings) are described in detail. Examples are given of structural plastics used in friction units subjected to mechano-chemical wear and of polymer films/coatings for protecting metal objects against corrosion.
Plastic-esthetic periodontal and implant surgery: A microsurgical approach
Scientific knowledge and practical experience to provide a comprehensive overview of the principles, indications, and clinical techniques of plastic-esthetic periodontal and implant microsurgery, focusing especially on minimal soft tissue trauma and maximally perfect wound closure. Microsurgery provides clinically relevant advantages over conventional macrosurgical concepts for regenerative and plastic-esthetic periodontal surgery, especially in the all-important esthetic zone. The microsurgical principles and procedures presented in the book are explained step-by-step in meticulously illustrated case examples with large, exquisite images. Each case example also includes an illustrated armamentarium of the materials and instruments necessary for the practical implementation of the microsurgical procedure. The book concludes with instructions on how to manage all major complications for each procedure.
Plaster, Render, Paint and Coatings : Details, Products, Case Studies
Describe and define the basic essentials, show what to look for and offer valuable tips for practical applications. Taking two example buildings, the authors also document the structural design of all important connection points at a scale of 1:10. New building or renovation: solutions for the application of plaster and paint. Guide: Which paint for which surfaces? Design details for solutions with external thermal insulation composite systems. Separate manufacturer s guidelines for plasters and paints. 8 realized buildings show what plaster, colour and coatings can achieve. A valuable reference book for planning and study
Plant Resistance to Arthropods : Molecular and Conventional Approaches
Arthropod resistant crops reduce pesticide pollution, alleviate hunger and improve human nutrition. Plant Resistance to Arthropods - Molecular and Conventional Approaches synthesizes new information about the environmental advantages of plant resistance, transgenic resistance, the molecular bases of resistance, and the use of molecular markers to map resistance genes. Readers are presented in-depth descriptions of techniques to quantify resistance, factors affecting resistance expression, and the deployment of resistance genes. New information about gene-for-gene interactions between resistant plants and arthropod biotypes is discussed along with the recent examples of using arthropod resistant plants in integrated pest management systems.
Plant Propagation by Tissue Culture ; 3rd Ed. ; Vol.1 : The Background
our knowledge of plant development, genetics physiology, biochemistry and molecular biology has expanded exponentially – often through work on mutants of Arabidopsis – and opened up many new avenues for the plant propagator to explore. Equally, the commercial significance of plant propagation has increased significantly. As an example, in the second edition there was a single chapter on plant growth regulators – in this there are three, reflecting the fact that not only is there more information on those PGRs we recognised in 1993, but that several new ones are now known. Equally, fifteen years ago we knew little of the molecular basis of plant development e. g. flower and shoot development, in this edition it has merited a whole chapter, much of which relates to discoveries in the last decade. Because of these factors, it was felt that a different approach was required for this edition.
Plant Ecology, Herbivory, and Human Impact in Nordic Mountain Birch Forests
The successful long-term sustainable management of forests is dependent on our knowledge of their history, present state, and responses to changing environmental conditions. In this light, the text evaluates the Nordic mountain birch ecosystem with examples from different sites in the Nordic countries and Scotland. The authors analyse vegetation and soils, and investigate the influence of climate change, insect pests, grazing pressure by sheep and reindeer, construction of roads and other consequences of increasing tourism. The possibilities for a sustainable use of the Nordic mountain birch forests are discussed in various models.
Planning Demand-Driven Disassembly for Remanufacturing
Ian M. Langella examines the planning of disassembly for remanufacturing of used products, yielding components which are reassembled into “as good as new” items. Through a thorough analysis of the underlying planning problem, fundamental insights are attained and heuristic solution methods are developed and tested. Although the heuristics exhibit good performance, they remain simple enough to be applied to industrial-sized problems. The author considers both settings where yields are deterministic and stochastic and where the amount of returned products is constrained.
Planning Abu Dhabi : An Urban History
Alamira Reem, a native Abu Dhabian and urban planner and researcher who has studied the emirate’s development for more than a decade, is uniquely placed to write its urban history. Following the introduction and description of Abu Dhabi’s early modern history, she focuses on three distinct periods dating from the discovery of oil in 1960, and coinciding with periods in power of the three rulers since then: Sheikh Shakhbut bin Sultan Al Nahyan (1960–1966), Sheikh Zayed bin Sultan Al Nahyan (1966–2004), and Sheikh Khalifa bin Zayed Al Nahyan (2004–). Based on archival research, key interviews and spatial mapping, she analyses the different approaches of each ruler to development; investigates the role of planning consultants, architects, developers, construction companies and government agencies; examines the emergence of comprehensive development plans and the policies underlying them; and assesses the effects of these many and varied influences on Abu Dhabi’s development.
