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Hugo and Russell's pharmaceutical microbiology
Microbiology is one of the essential pharmaceutical sciences upon which the study and practice of pharmacy is built. It has a bearing on all aspects of the manufacture of medicines and sterile products, from their design and development to their delivery as quality products. Few interventions are more central to modern medicine than the treatment of infection, where antibiosis, vaccination and hygienic practices have essential roles to play. The COVID-19 pandemic, the appearance of new pathogens and the rise of antibiotic resistance have demonstrated most completely the need for pharmaceutical practitioners, researchers and industrial scientists to be fully conversant with this field. The 9th edition of Hugo and Russell’s Pharmaceutical Microbiology has been updated to meet this need. Having long served as the sole comprehensive textbook covering this subject, it has now been adapted to a critical new period in the advancement of medical and pharmaceutical research and development. Its experienced editors have incorporated contributions from subject experts and created a text which will serve the next generation of pharmacy students, pharmaceutical industry scientists and researchers.
How to Practice Academic Medicine and Publish from Developing Countries? : A Practical Guide
The book provides an overview of the state of research in developing countries – Africa, Latin America, and Asia (especially India) and why research and publications are important in these regions. It is written mainly by senior colleagues who have experienced and recognized the challenges with design, documentation, and publication of health research in the developing world. The book includes short chapters providing insight into planning research at the undergraduate or postgraduate level, issues related to research ethics, and conduct of clinical trials.
How to Examine the Nervous System
This textbook simplifies the apparent complexity of the neurological examination to make it completely understandable and satisfying to perform. With simple prose and numerous helpful illustrations, the author describes in detail reliable bedside examination techniques that will pinpoint the location of a lesion in the nervous system and lead to a resolution of the problem.
How to Develop Your Career in Dental Nursing
Guidance is included throughout, and the reader should use the book to make informed decisions and conduct further research for the benefit of their own career. The book considers the historical context, along with reviewing the current position of dental nursing and considering the future of the field, all with the overarching theme of helping dental nurses further their career in modern dentistry.
How to Build a Modern Tontine : Algorithms, Scripts and Tips
This book introduces the modern tontine and its applications in retirement and decumulation. Personal financial management in the later stages of life presents unique challenges, and renowned retirement planning expert Dr. Milevsky proposes the modern tontine as a solution. With the goal of guiding professionals and retirees in more efficient decumulation, the book demonstrates how to build a modern tontine. It is technically oriented, employing a cookbook format, featuring R code, and examining retirement planning through a statistical lens.
How the immune system recognizes self and nonself : Immunoreceptors and their signaling
This brain function must have been particularly important for most animals to protect their lives from enemies and for species to survive through evolution. Similarly, higher organisms have also acquired their immune system through evolution that discriminates nonself pathogens and self-body to protect their lives from pathogens such as bacteria or viruses. The brain system may distinguish integrated images of self and nonself created from many inputs, such as vision, sound, smell, and others. The immune system recognizes and distinguishes a variety of structural features of self and nonself components. The latter actually include almost everything but self.
How Long Do We Live? : Demographic Models and Reflections on Tempo Effects
The book reviews the debate on how best to measure period longevity. In the various chapters, leading experts in demography critically examine the existence of the tempo effect in mortality, present extensions and applications, and compare period and cohort longevity measures. The book provides a deeper understanding of and new insights into the fundamental question "How long do we live"?
How Ficta Follow Fiction : A Syncretistic Account of Fictional Entities
This book presents a novel theory of fictional entities which is syncretistic insofar as it integrates the work of previous authors. It puts forward a new metaphysical conception of the nature of these entities, according to which a fictional entity is a compound entity built up from both a make-believe theoretical element and a set theoretical element. The fictional entity is constructed by imagining the existence of an individual with certain properties and adding a set-theoretical element consisting of the set of properties corresponding to the properties of the imagined entity.
How Data Quality Affects our Understanding of the Earnings Distribution
This book demonstrates how data quality issues affect all surveys and proposes methods that can be utilised to deal with the observable components of survey error in a statistically sound manner. This book begins by profiling the post-Apartheid period in South Africa's history when the sampling frame and survey methodology for household surveys was undergoing periodic changes due to the changing geopolitical landscape in the country. This book profiles how different components of error had disproportionate magnitudes in different survey years, including coverage error, sampling error, nonresponse error, measurement error, processing error and adjustment error.
Hot house : Global climate change and the human condition
Global warming is extremely complex because it deals with so many different characteristics of the Earth and their complex interactions. It is addressed by almost all sciences including many aspects of geosciences, atmospheric, the biological sciences, and even astronomy. It has recently become the concern of other diverse disciplines such as economics, agriculture, demographics and population statistics, medicine, engineering, and political science. This book attempts to address these complex interactions, integrate them, and derive meaningful conclusions and possible solutions.
Hot cracking phenomena in welds
The first chapter provides an overview of the various hot cracking phenomena. Different mechanisms of solidification cracking proposed in the past decades are summarized and new insight is particularly given into the mechanism of ductility dip cracking. The effects of different alloying elements on the hot cracking resistance of various materials are shown in the second chapter and, as a special metallurgical effect, the initiation of stress corrosion cracking at hot cracks has been highlighted. The third chapter outlines how numerical analyses and other modelling techniques can be utilized to describe hot cracking phenomena and how such results might contribute to the explanation of the mechanisms. Various hot cracking test procedures are presented in the final chapter with a special emphasis on standardization. For the engineering and natural scientists in research and development the book provides both, new insight and a comprehensive overview of hot cracking phenomena in welds. The contributions additionally give numerous individual solutions and helpful advice for international welding engineers to avoid hot cracking in practice. Furthermore, it represents a very helpful tool for upper level metallurgical and mechanical engineering students.
Hormones, metabolism and the benefits of exercise
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Horizons of Combinatorics
Hungarian mathematics has always been known for discrete mathematics, including combinatorial number theory, set theory and recently random structures, combinatorial geometry as well. The recent volume contains high level surveys on these topics with authors mostly being invited speakers for the conference "Horizons of Combinatorics" held in Balatonalmadi, Hungary in 2006. The collection gives a very good overview of recent trends and results in a large part of combinatorics and related topics, and offers an interesting reading for experienced specialists as well as to young researchers and students.
Homotopy-Based Methods in Water Engineering
Exploring the concept of homotopy from topology, different kinds of homotopy-based methods have been proposed for analytically solving nonlinear differential equations, given by approximate series solutions. Homotopy-Based Methods in Water Engineering attempts to present the wide applicability of these methods to water engineering problems. It solves all kinds of nonlinear equations, namely algebraic/transcendental equations, ordinary differential equations (ODEs), systems of ODEs, partial differential equations (PDEs), system of PDEs, and integro-differential equations using the homotopy-based methods
Homotopy Methods in Topological Fixed and Periodic Points Theory
The notion of a fixed point plays a crucial role in numerous branches of mat- maticsand its applications. Informationabout the existence of such pointsis often the crucial argument in solving a problem. In particular, topological methods of fixed point theory have been an increasing focus of interest over the last century. These topological methods of fixed point theory are divided, roughly speaking, into two types. The ?rst type includes such as the Banach Contraction Principle where the assumptions on the space can be very mild but a small change of the map can remove the fixed point. The second type, on the other hand, such as the Brouwer and Lefschetz Fixed Point Theorems, give the existence of a fixed point not only for a given map but also for any its deformations. This book is an exposition of a part of the topological fixed and periodic point theory, of this second type, based on the notions of Lefschetz and Nielsen numbers. Since both notions are homotopyinvariants, the deformationis used as an essential method, and the assertions of theorems typically state the existence of fixed or periodic points for every map of the whole homotopy class, we refer to them as homotopy methods of the topological fixed and periodic point theory.
Homogenization of Partial Differential Equations
Homogenization is a method for modeling processes in microinhomogeneous media, which are encountered in radiophysics, filtration theory, rheology, elasticity theory, and other domains of mechanics, physics, and technology. These processes are described by PDEs with rapidly oscillating coefficients or boundary value problems in domains with complex microstructure. From the technical point of view, given the complexity of these processes, the best techniques to solve a wide variety of problems involve constructing appropriate macroscopic (homogenized) models. The present monograph is a comprehensive study of homogenized problems, based on the asymptotic analysis of boundary value problems as the characteristic scales of the microstructure decrease to zero. The work focuses on the construction of nonstandard models: non-local models, multicomponent models, and models with memory.
Homo Oeconomicus : The Economic Model of Behaviour and Its Applications in Economics and Other Social Sciences
The economic model of behaviour is fundamental not only in economic theory, but also in modern approaches of other social sciences, above all in political science and law. This book provides a comprehensive treatise of the general model, its philosophical and methodological foundations and its applications in different fields. In addition to the basic model, extensions to its assumptions are examined to account for complex applications like low-cost situations with moral behaviour. Finally, the book takes a broader perspective by evaluating the impact of the model on economic policy and on the development of the field of social science as a whole, such as the competition between individualistic and collectivist approaches.
Holonic and multi-agent systems for manufacturing ; 2nd International conference on industrial applications of holonic and multi-agent systems, HoloMAS 2005, Copenhagen, Denmark, August 22-24, 2005, Proceedings
The challenge faced in today’s manufacturing and business environments is the question of how to satisfy increasingly stringent customer requirements while managing growing system complexity. For example, customers expect high-quality, customizable, low-cost products that can be delivered quickly. The systems that deliver these expectations are by nature distributed, concurrent, and stochastic, and, as a result, increasingly difficult to manage. Unfortunately, the traditional hierarchical, strictly centralized approach to control used in these domains is characteristically inflexible, fragile, and difficult to maintain. These shortcomings have led to the development of a new class of manufacturing and supply-chain decision-making approaches in recent years. Solutions based on these approaches usually explore a set of highly distributed decision-making units that are capable of autonomous operations while cooperating interactively to resolve larger problems. The units, referred to as agents in classical computer science and software engineering, or holons if physically integrated with the manufacturing hardware, interact by exchanging information. These units are motivated by arriving at local solutions as well as collaborating and sharing resources and goals in solving the overall problem in question collectively.
Holomorphic Morse Inequalities and Bergman Kernels
The main analytic tool is the analytic localization technique in local index theory developed by Bismut-Lebeau. The book includes the most recent results in the field and therefore opens perspectives on several active areas of research in complex, Kähler and symplectic geometry. A large number of applications are included, e.g., an analytic proof of the Kodaira embedding theorem, a solution of the Grauert-Riemenschneider and Shiffman conjectures, a compactification of complete Kähler manifolds of pinched negative curvature, the Berezin-Toeplitz quantization, weak Lefschetz theorems, and the asymptotics of the Ray-Singer analytic torsion.
Holomorphic Functions in the Plane and n-dimensional Space
Complex analysis nowadays has higher-dimensional analoga: the algebra of complex numbers is replaced then by the non-commutative algebra of real quaternions or by Clifford algebras. During the last 30 years the so-called quaternionic and Clifford or hypercomplex analysis successfully developed to a powerful theory with many applications in analysis, engineering and mathematical physics. This textbook introduces both to classical and higher-dimensional results based on a uniform notion of holomorphy. Historical remarks, lots of examples, figures and exercises accompany each chapter.
