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Adrenomedullin in Cardiovascular Disease
Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.
Adipose-derived stem cells : Methods and protocols
Discusses of the latest technology and advancements in the field of human-derived ASC and SVF. The chapters in this book are organized into four parts. Part One focuses on human ASC’s isolation, characterization, and differentiation. Part Two describes the isolation and characterization of ASC and SVF from canine, feline, and murine tissues. Part Three looks at hydrogels, scaffolds, and microphysiological systems, and Part Four talks about the new assays and applications using ASC. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Acute Promyelocytic Leukemia : Molecular Genetics, Mouse Models and Targeted Therapy
Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.
Acute Myelogenous Leukemia
The focus is on selected critical molecular determinants of AML pathogenesis and pathophysiology and the exploitation of these factors by diverse therapeutic agents and modalities. Bringing together new concepts and findings in the basic and clinical science of AML, the book emphasizes the molecular basis for new therapies that stand to have the greatest potential impact on the clinical face of these diseases. The text provides insights into selected novel strategies currently and prospectively being developed, including interruption of specific signal transduction pathways, modulation of gene expression, attempts to reinstate differentiation, and immunomodulation.
Acidity and Basicity
This is the first handbook on zeolites and other microporous materials. It is an up-to-date, highly sophisticated collection of information for those who deal with zeolites in industry or at academic institutions as well as being a guide for newcomers.
Acceleration and Improvement of Protein Identification by Mass Spectrometry
This book is presenting a review of basic proteomic techniques. The second part of the book is related to the novel high throughput protein identification technique called the 'molecular scanner'
About Life : Concepts in Modern Biology
This book uses modern biological knowledge to tackle the question: "What distinguishes living organisms from the non-living world?" In the first few chapters, the authors draw on recent advances in cell and molecular biology to develop an account of the "living state" that applies to all organisms, but only to organisms. Subsequent chapters use this account to explore questions about evolution, the origin of life and the possibility of extraterrestrial life. Towards the end of the book the authors consider human evolution, intelligence and the extent to which our species can be regarded as biologically unique. About Life is written as far as possible in non-technical language; all scientific terms are explained straightforwardly when they are introduced. It is aimed at the general, non-specialist reader, but the novel approach that it takes to general issues in biology will also interest students of the life sciences.
A Personal History of Nuclear Medicine
In A Personal History of Nuclear Medicine, Dr. Henry N. Wagner, Jr. outlines his significant contribution to the field of nuclear medicine over the past half-century, while also discussing the hurdles that the field faced in becoming a major component of modern medical practice. Further, the author explores challenges within the academic and medical establishments, which have often been known for resisting change
A Dictionary of Biomedicine
A Dictionary of Biomedicine fills the need to define the specialist language used within an evolving field by offering clear, concise definitions of even the most complex biomedical terms. It includes more than 10,000 A-Z entries on all areas of biomedicine, such as genomics and biomedical science. Entries are authoritative and wide-ranging, covering terms from the related areas of anatomy, genetics, molecular bioscience, pathology, pharmacology, and clinical medicine.
A Computer Scientists Guide to Cell Biology
Provides a succinct treatment of the general concepts of cell biology, furnishing the computer scientist with the tools necessary to read and understand current literature in the field.After a brief introduction to cell biology, the text focuses on the principles behind the most-widely used experimental procedures and mechanisms, relating them to well-understood concepts in computer science. The presentation of the material has been prepared for the reader’s quick grasp of the topic: comments on nomenclature and background notes can be ascertained at a glance, and essential vocabulary is boldfaced throughout the text for easy identification.
3D cell culture : Methods and protocols
Expands on the previous edition with discussions about the latest organoid models developed for many more organs; new hydrogels and devices for 3D culture; and the organoid systems that have been improved by incorporating more components of tissue microenvironments in the in vitro culture. The chapters in this book are organized into five parts and cover topics such as biofabrication, organoids, microfluidic systems, bioprinting, and image analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
34th Hemophilia symposium Hamburg 2003 ; HIV infection and epidemiology ; Management of bleedings in hemophiliacs with inhibitors ; orthopedic problems and therapy in hemophiliacs ; Therapy with protein C ; Pediatric Hemostaseology ; Free Lectures
This book contains the contributions to the 34th Hemophilia Symposium, Hamburg 2003. The main topics are HIV infection and epidemiology, management of bleedings in hemophiliacs with inhibitors, orthopedic problems and therapy in hemophiliacs, therapy with protein C and pediatric hemostaseology. The volume is rounded off by numerous free papers and posters on hemophilia, hemophiliacs with inhibitors, thrombophilia and molecular diagnostics.
25 Years of P53 Research
Communication, awareness and access to information: Given the complexity of the field and the fact that data pertaining to each particular aspects of p53 biology or deregulation are scattered in many different publications, it is extremely difficult to access the full scale of relevant information of any specific p53-related topic. This book may help in this task by putting into perspective both general considerations on the p53 pathway and more specific information on various aspects of p53. In the longer term, however, open access to p53 complexity will require the development of knowledge bases accessible through the web and using simple navigation tools to guide users towards the specific information they need. Several efforts are currently being developed in that direction. They need to be strenghtened and better integrated within the rapidly growing galaxy of web-based information sources on molecular and individual variations in cancer. 2. Reference functional assays and structural analysis: Given the huge diversity of cellular and animal models for wild-type or mutant p53 functions, it will be important to set up standard, universally accepted assays to measure critical p53 protein functions.
