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Molecular Biology of Metal Homeostasis and Detoxification : From Microbes to Man
One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.
Molecular autoimmunity
The autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important challenge. Over the last few years, our understanding of the pathogenesis of autoimmune diseases has improved rapidly, leading to the emergence of elegant immunointervention strategies. Molecular Autoimmunity illustrates how cutting-edge research is continuing to advance our understanding of autoimmune disease mechanisms and identifies novel therapeutic targets that provide a hope for effective future treatments. This volume contains a selected number of exciting advances in unraveling autoimmune reactions, and the resulting new armory of experimental immunotherapies that may lead to new ways of controlling autoimmune reactions.
Modules and Comodules
The 23 articles in this volume encompass the proceedings of the International Conference on Modules and Comodules held in Porto (Portugal) in 2006 and dedicated to Robert Wisbauer on the occasion of his 65th birthday. These articles reflect Professor Wisbauer's wide interests and give an overview of different fields related to module theory, some of which have a long tradition whereas others have emerged in recent years. They include topics in the formal theory of modules bordering on category theory, in ring theory, in Hopf algebras and quantum groups, and in corings and comodules.
Modern Trends in Geomechanics
This book is loaded with rich and stimulating articles by a roster of brilliant scholars, reflecting some recent trends in the frontier research of geomechanics. This collection of 32 contributions stems from an international workshop on "Modern Trends of Geomechanics" held in Vienna. The contributions span a wide range of topics and an enormous range of physical scales, from micromechanics at grain scale to engineering problems at large scale; from laboratory and field testing over constitutive modelling to numerical analysis.
Modern tools and methods of water treatment for improving living standards ; Proceedings of the NATO Advanced Research Workshop on modern tools and methods of water treatment for improving living standards, Dnepropetrovsk, Ukraine, November 19-22, 2003
In 2001, one in seven of the water samples taken from Ukrainian industrial and drinking water supply systems did not meet sanitary-hygienic standards, and one in twelve did not meet microbiological standards.
Modern Control Systems ; 14th ed.
Written to be equally useful for all engineering disciplines, this text is organized around the concepts of control systems theory in the context of frequency and time domains. It provides coverage of both classical and modern methods of control engineering to give students a strong foundation in basic principles that they can utilize to explore advanced topics in later chapters. Emphasis is placed on real-world complex control systems and practical design applications as well as evolving design strategies like green engineering and human-centered design. Problem solving is strongly emphasized, with an abundance of problems of increasing complexity that help students learn to apply theory to computer-aided design and analysis concepts using MATLAB® and LabVIEW MathScript.
Modern Control Systems ; 13th ed.
Presents the structure of feedback control theory and to provide a sequence of exciting discoveries. The book demonstrates various real-world, global engineering problems while touching on evolving design strategies like green technology. Some of the themes at-hand include climate change, clean water, sustainability, waste management, emissions reduction, and minimizing energy. Throughout the text, students apply theory to the design and analysis of control systems.
Models in Software Engineering ; Workshops and Symposia at MoDELS 2007, Nashville, TN, USA, September 30 - October 5, 2007, Reports and Revised Selected Papers
This book constitutes the thoroughly refereed post-workshop proceedings of 10 internationl workshops and 2 symposia held as satellite events of the 10th International Conference on Model Driven Engineering Languages and Systems, MoDELS 2007, in Nashville, TN, USA, in September/October 2007 (see LNCS 4735).The 29 revised full papers were carefully selected for inclusion in the book and are presented along with a doctoral and an educators' symposium section. The papers are organized in topical sections representing the various workshops: aspect-oriented modeling (AOM 2007), language engineering (ATEM2007), model driven development of advanced user interfaces (MDDAUI 2007), model size metrics (MSM 2007).
Models in Software Engineering ; Workshops and Symposia at MoDELS 2006, Genoa, Italy, October 1-6, 2006, Reports and Revised Selected Papers
This book constitutes the thoroughly refereed post-proceedings of 11 international workshops held as satellite events of the 9th International Conference on Model Driven Engineering Languages and Systems, MoDELS 2006, in Genoa, Italy, in October 2006 (see LNCS 4199). The 32 revised full papers were carefully selected for inclusion in the book.
Modelling water and nutrient dynamics in soil-crop systems : Applications of different models to common data sets - Proceedings of a workshop held 2004 in Müncheberg, Germany
This book contains articles from a workshop on "Modelling water and nutrient dynamics in crop-soil systems". Data sets from lysimeters and experimental fields of multiyear crop rotations were provided for modellers. A unique data set is provided of a 100 year long term field experiment regarding crop yield and organic carbon development under different management systems. The book includes a detailed description of data sets which can be used by modellers and the papers describe the applications of 18 different modelling approaches describing soil-crop-atmosphere interactions for water, nitrogen and carbon dynamics.
Modelling Autonomic Communications Environments ; 3rd IEEE International Workshop, MACE 2008, Samos Island, Greece, September 22-26, 2008. Proceedings
Research and development of autonomics have come a long way, and we are delighted to present the proceedings of the 3rd IEEE International Workshop on Modelling Autonomic Communications Environments (MACE 2008).Asin the last two years, this workshopwasheld aspart of Manweek, the International Week on Management of Networks and Services, which took place on the lovely Island of Samos in Greece .MACE started as anexperimentin2006,andcreatedasmallcommunitythat nowfnds it self attracted backeachyearby afeeling ofexcitement-thatthere is something new going on. Certainly, MACE is not as shiny or practiced as other well-known conferences and workshops, but we consider this a feature of the workshopitself.
Modeling of Soft Matter
Soft matter plays a role in a wide variety of important processes and application. For example, gel swelling and dynamics are an essential part of many biological and individual processes, such as motility mechanisms in bacteria and the transport and absorption of drugs. Ferroelectrics, liquid crystals, and elastomers are being used to design ever faster switching devices. Experimental studies, such as scattering, optical and electron microscopy, have provided a great deal of detailed information on structures. But the integration of mathematical modeling and analysis with experimental approaches promises to greatly increase our understanding of structure-property relationships and constitutive equations. The workshop on Modeling of Soft Matter has taken such an integrated approach.
Modeling Communication with Robots and Virtual Humans ; Second ZiF Research Group International Workshop on Embodied Communication in Humans and Machines, Bielefeld, Germany, April 5-8, 2006, Revised Selected Papers
The 17 articles in this state-of-the-art survey address artificial intelligence research on communicative agents and also provide an interdisciplinary perspective from linguistics, behavioral research, theoretical biology, philosophy, communication psychology, and computational neuroscience. The topics include studies on human multimodal communication; the modeling of feedback signals, facial expression, eye contact, and deception; the recognition and comprehension of hand gestures and head movements; communication interfaces for humanoid robots; the evolution of cognition and language; emotion and social appraisal in nonverbal communication; dialogue models and methodologies; theory of mind and intentionality; complex systems, dynamic field theory, and connectionist modeling.
Modeling and Using Context ; 5th International and Interdisciplinary Conference, CONTEXT 2005, Paris, France, July 5-8, 2005, Proceedings
Context is of crucial importance for research and applications in many disciplines, as evidenced by many workshops, symposia, seminars, and conferences on specific aspects of context. The International and Interdisciplinary Conference on Modeling and Using Context (CONTEXT), the oldest conference series focusing on context, provides a unique interdisciplinary emphasis, bringing together participants from a wide range of disciplines, including artificial intelligence, cognitive science, computer science, linguistics, organizational science, philosophy, psychology, ubiquitous computing, and application areas such as medicine and law, to discuss and report on context-related research and projects. Previous CONTEXT conferences were held in Rio de Janeiro, Brazil (1997), Trento, Italy (1999, LNCS 1688), Dundee, UK (2001, LNCS 2116), and Palo Alto, USA (2003, LNCS 2680). CONTEXT 2005 was held in Paris, France during July 5–8, 2005. There was a strong response to the CONTEXT 2005 Call for Papers, with 120 submissions received. A careful review process assessed all submissions, with each paper first reviewed by the international Program Committee, and then reviewer discussions were initiated as needed to assure that the final decisions carefully considered all aspects of each paper. Reviews of submissions by the Program Chairs were supervised independently and anonymously, to assure fair consideration of all work. Out of the 120 submissions, 23 were selected as full papers for oral presentation, and 20 were selected as full papers for poster presentation. These outstanding papers are presented in this proceedings.
Modeling and Retrieval of Context ; 2nd International Workshop, MRC 2005, Edinburgh, UK, July 31-August 1, 2005, Revised Selected Papers
Computing in context has become a necessity in modern and intelligent IT - plications. With the use of mobile devices and current research on ubiquitous computing, context-awareness has become a major issue. However, context and context-awareness are crucial not only for mobile and ubiquitous computing. They are also vital for spanning various application areas, such as collaborative softwareand Web engineering,personaldigital assistantsand peer-to-peer inf- mation sharing, health care work?ow and patient control, and adaptive games and e-learning solutions. In these areas, context serves as a major source for reasoning, decision making, and adaptation, as it covers not only application knowledge but also environmental knowledge.Likewise, modeling and retrieving context is an important part of modern knowledge management processes.
Model-Driven Development of Reliable Automotive Services ; 2nd Automotive Software Workshop, ASWSD 2006, San Diego, CA, USA, March 15-17, 2006, Revised Selected Papers
This book constitutes the thoroughly refereed post-workshop proceedings of the Second Automotive Software Workshop, ASWSD 2006, held in San Diego, CA, USA in March 2006.The 11 revised full papers presented were carefully reviewed and selected from 18 lectures held at the workshop, that brought together experts from industry and academia, working on highly complex, distributed, reactive software systems related to the automotive domain. The papers are organized in topical sections on modeling techniques and infrastructures, model transformations, quality assurance, real-time control, as well as services and components.
Model-Driven Architecture - Foundations and Applications ; 2nd European Conference, ECMDA-FA 2006, Bilbao, Spain, July 10-13, 2006, Proceedings
The goal of the European Conference on Model-Driven Architecture — Foundations and Applications (ECMDA-FA) is to bring together industry and academia to tackle the problems in model-driven development. This volume includes 18 foundation papers and 12 application papers, which is a fine balance between both worlds. ECMDA-FA 2006 also hosted six workshops on both theoretical and practical aspects of MDA. Furthermore, the keynote speakers, David Frankel and Bran Selic, from some of the world’s largest IT companies proved that industry is very much involved in MDA. This second ECMDA-FA conference is the result of the work of the authors who submitted a total of 78 papers, the Program Committee members who took the effort to review the papers, the people organizing the workshops, and of course the Steering Committee. All in all, several hundreds of people have worked hard to make this conference a success.
Model-Based Software and Data Integration ; 1st International Workshop, MBSDI 2008, Berlin, Germany, April 1-3, 2008. Proceedings
The First International Workshop on Model-Based Software and Data Integ- tion (MBSDI 2008), was ourfrst event of this kind in a forthcoming series of activities at TU Berlin, where a scientifc discussion and exchange forum was provided for both academic and industrial researchers. We aimed at researchers, engineersand practitionerswho focus onadvanced, model-basedsolutions inthe area of software and information integration and interoperability. As withevery beginning, the resonanceonour callsin today's overfoodingof workshops was somewhat unpredictable, and we did not really know how many paper submissions to expect. We were nicely surprised, considering the rather short lead time to organize the meeting and the very specialized and focused topic.
Model Driven Engineering Languages and Systems ; Vol. 4199 ; 9th International Conference, MoDELS 2006, Genova, Italy, October 1-6, 2006, Proceedings
This book constitutes the refereed proceedings of the 9th International Conference on Model Driven Engineering Languages and Systems (formerly the UML series of conferences), MoDELS 2006, held in Genova, Italy, in October 2006. The 51 revised full papers and 2 invited papers presented were carefully reviewed and selected from 178 initial submissions. The papers are organized in topical sections on evaluating UML, MDA in software development, concrete syntax, applying UML to interaction and coordination, aspects, model integration, formal semantics of UML, security, model transformation tools and implementation, analyzing dynamic models, specifying transformations, MOF, bridging models, risk, trust and dependability, tool environments, OCL, roundtrip engineering, real time and embedded systems, as well as workshops, tutorials and panels.
Model Driven Engineering Languages and Systems ; 11th International Conference, MoDELS 2008, Toulouse, France, September 28 - October 3, 2008. Proceedings
The book also contains three keynote speeches and contributions to workshops, symposia, tutorials and panels at the conference. The papers are organized in topical sections on Model Transformation: Foundations; Requirements Modeling; Domain-Specific Modeling; Model Transformation: Techniques, Composition and Analysis of Behavioral Models; Model Comprehension; Model Management; Behavioral Conformance and Refinement; Metamodeling and Modularity; Constraints; Model Analysis; Service-Oriented Architectures; Adaptive and Autonomic Systems; Empirical Studies; Evolution and Reverse Engineering; Modeling Language Semantics; Dependability Analysis and Testing; Aspect-Oriented Modeling; Structural Modeling;and Embedded Systems.
