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Drug interactions in infectious diseases : Antimicrobial drug interactions
Delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.
Drug development and approval process
Drug discovery is the process of identifying and characterizing molecules with the potential to safely modulate disease, with a goal to bring medicines that can improve the lives of patients. It is a lengthy and resource intensive process, that requires close cooperation across multiple disciplines. Optimizing the process of drug discovery is of great interest to the pharmaceutical industry, as the efficient identification and selection of suitable drug candidates can have a dramatic impact on the cost and profitability of new medicines.
Drug Courts : A New Approach to Treatment and Rehabilitation
This cutting-edge sourcebook is ideal for physicians, addiction treatment practitioners, probation officers, testing programs, judges and anyone else facing challenges in practice with the treatment of drug court participants. This book includes knowledge in treatment of addiction and withdrawal, treatment for patients with dual diagnoses of mental illness and addiction, and treatment of diseases associated with drug use, such as tuberculosis, hepatitis, and HIV infection. Unparalleled discussions of the drug court system and the medical problems of drug court patients are presented.
Driving smart medical diagnosis through AI-powered technologies and applications
Driving Smart Medical Diagnosis Through AI-Powered Technologies and Applications serves as a solution in this era of transformative healthcare and addresses these challenges head-on. It unravels the complexities surrounding the implementation of AI in healthcare, offering in-depth discussions on the latest breakthroughs. From unraveling the mysteries of AI-driven cataract detection to exploring the implications of decentralized mammography classification, the book is a valuable resource that equips scholars with the knowledge to navigate this innovative landscape.
Drift-Driven Design of Buildings : Mete Sozen’s Works on Earthquake Engineering
Summarizes the most essential concepts that every engineer designing a new building or evaluating an existing structure should consider in order to control the damage caused by drift (deformation) induced by earthquakes. It presents the work on earthquake engineering done by Dr. Mete Sozen and dozens of his collaborators and students over decades of experimentation, analysis, and reconnaissance. Many of the concepts produced through this work are integral part of earthquake engineering today. Nevertheless, the connection between the concepts in use today and the original sources is not always explained.
Drawing for Interior Design ; 2nd ed.
Covers all stages of visual presentation as part of the interior design process, from the most basic initial sketches to fully developed computer-generated visualizations. Following a brief introduction four chapters take the reader through the design process, from the basics to conception, presentation and production. This second edition includes more practical advice on techniques, more case studies, step-by-step sequences and updated examples. With a varied and comprehensive range of images, this book is an invaluable, inspirational and practical resource for interior design students.
DNA Conformation and Transcription
the first book that compiles the fruits of the studies that have been performed to date to solve the riddle ‘written’ in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code".
Distributed, High-Performance and Grid Computing in Computational Biology ; International Workshop, GCCB 2006, International Workshop, GCCB 2006, Eilat, Israel, January 21, 2007, Proceedings
Modern computational biology and bioinformatics are characterized by large and complex structured data and by applications requiring considerable computing resources, such as processing units, storage elements and software programs. In addition, these disciplines are intrinsically geographically distributed in terms of their instruments, communities and computing resources. Tackling the computational challenges in computational biology and bioinformatics increasingly requires high-end and distributed computing infrastructures, systems and tools.
Distributed Services with OpenAFS : For Enterprise and Education
This book shows in detail how to build enterprise-level secure, redundant, and highly scalable services from scratch on top of the open source Linux operating system, suitable for small companies as well as big universities. The core architecture presented is based on Kerberos, LDAP, AFS, and Samba. It is shown how to integrate web, message related, data base and other services with this backbone. This architecture provides a Single-Sign-On solution for different client platforms and can also be employed for clustering. Although it is implemented with Debian GNU/Linux, the content can be applied to other UNIX flavors.
Distributed embedded systems : Design, middleware and resources ; IFIP 20th World computer congress, TC10 Working conference on distributed and parallel embedded systems (DIPES 2008), September 7-10, 2008, Milano, Italy
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.
Dissipative Solitons : From Optics to Biology and Medicine
The dissipative soliton concept is a fundamental extension of the concept of solitons in conservative and integrable systems. It includes ideas from three major sources, namely standard soliton theory developed since the 1960s, nonlinear dynamics theory, and Prigogine's ideas of systems far from equilibrium. These three sources also correspond to the three component parts of this novel paradigm. This book explains the above principles in detail and gives the reader various examples from optics, biology and medicine. These include laser systems, optical transmission lines, cortical networks, models of muscle contraction, localized vegetation structures and waves in brain tissues.
Dissecting Discrimination : Identifying Its Various Faces and Their Sources
This book examines the phenomenon of discrimination using a descriptive approach. Discrimination is omnipresent, whether it is people who discriminate against other people or, more recently, also machines that discriminate against people. The first part of the analysis employs decision theory on discrimination, leading to two fundamental subtypes: taste-based discrimination and statistical discrimination. The second part links taste-based discrimination to social identity theory, demonstrates that not all taste-based discrimination is ultimately statistical discrimination, and reveals the evolutionary origins of our tastes.
Discrete Optimization with Interval Data : Minmax Regret and Fuzzy Approach
This book is a valuable source of information for all operations research practitioners who are interested in modern approaches to problem solving. Apart from the description of the theoretical framework, it also presents some algorithms that can be applied to solve problems that arise in practice.
Dinaric Perspectives on TIMSS 2019 : Teaching and Learning Mathematics and Science in South-Eastern Europe
This book brings together national experts from across the Dinaric region to rigorously review IEA’s Trends in International Mathematics and Science Study (TIMSS) 2019 grade four data to develop a multidimensional and culturally sensitive perspective on their TIMSS 2019 primary-level results. The Dinaric region, named after the Dinaric Alps, is located in South-eastern Europe, and stretches through Croatia, Bosnia and Herzegovina, Serbia, Montenegro, Kosovo[1], Albania, and North Macedonia. IEA’s TIMSS has been an invaluable resource for monitoring international trends in mathematics and science achievement at grades four and eight since 1995. The TIMSS 2019 administration of the test to grade four students, provided a unique opportunity for analysis within shared regional settings and enabled the construction of this first report based on international study results from the region, prepared by the National Research Coordinators in collaboration with IEA.
Digitization of the management accounting function : A case study analysis on manufacturing companies
Analyzes the impact of digitization on management accounting in five manufacturing companies. It is one of the first in-depth empirical studies on the intersection of management accounting and digitization. The study suggests that there are two archetypes of digitization of the management accounting function. The first archetype emphasizes top-down-driven changes that aim to enhance efficiency, such as conducting tasks with a higher degree of automation in a leaner structure with fewer resources. The second archetype is strongly driven and initiated by employees in the management accounting function (bottom-up). The focus is on improving the use of data by applying innovative analytics methods, integrating additional sources of data, and benefiting from new technologies like artificial intelligence. The results of the study also indicate that digitization of the management accounting function is mostly in line with the overall company strategy.
Digital Watermarking ; Vol. 3710 ; 4th International Workshop, IWDW 2005, Siena, Italy, September 15-17, 2005, Proceedings
We are delighted to welcome the attendees of the Fourth International Wo- shop on Digital Watermarking (IWDW). Watermarking continues to generate strong academic interest. Commercialization of the technology is proceeding at a steadypace. We haveseen watermarkingadoptedfor DVD audio.Fingerpri- ing technology was successfully used to determine the source of pirated video material. Furthermore, a number of companies are using watermarking as an enabling technology for broadcast monitoring services. Watermarking of digital cinema contentis anticipated. Future applications may also come from areas- related to digital rights management. For example, the use of watermarking to enhance legacy broadcast and communication systems is now being considered. IWDW 2005 o?ers an opportunity to re?ect upon the state of the art in digital watermarking as well as discuss directions for future research and applications. This year we accepted 31 papers from 74 submissions. This 42% acceptance rate indicates our commitment to ensuring a very high quality conference.
Digital Towns : Accelerating and Measuring the Digital Transformation of Rural Societies and Economies
This book explores the digital transformation of small and rural towns, in particular, how to measure the evolution and development of digital towns. In addition to access to resources, competition from urban and global markets, and population trends, rural communities present lesser access and use of digital technologies and have lower digital competencies and skills than their urban counterparts. Consequently, they experience less beneficial outcomes from increased digitalisation than urban areas. This book defines what a digital town is and explores digitalisation from the perspective of the four basic economic sectors in towns - individuals and households, businesses, the public sector, and civil society - and three types of enabling infrastructure - digital connectivity, education, and governance.
Digital Signal Processing with Field Programmable Gate Arrays
Field-Programmable Gate Arrays (FPGAs) are revolutionizing digital signal processing as novel FPGA families are replacing ASICs and PDSPs for front-end digital signal processing algorithms. So the efficient implementation of these algorithms is critical and is the main goal of this book. It starts with an overview of today's FPGA technology, devices, and tools for designing state-of-the-art DSP systems. A case study in the first chapter is the basis for more than 40 design examples throughout. The following chapters deal with computer arithmetic concepts, theory and the implementation of FIR and IIR filters, multirate digital signal processing systems, DFT and FFT algorithms, advanced algorithms with high future potential, and adaptive filters. Each chapter contains exercises. The VERILOG source code and a glossary are given in the appendices. This edition has a new chapter on microprocessors, new sections on special functions using MAC calls, intellectual property core design and arbitrary sampling rate converters, and over 100 new exercises.
Digital project management strategic theory and practice ; Vol 31
Foundational resource for courses on digital project management methods, offering step-by-step guidance and real-world examples. It provides actionable insights into implementing digital tools in project management studies, from data collection to visualization. The book also highlights the role of strategic theory and practice in project management strategic decision-making across project planning, execution, monitoring and control management.
Digital platforms in finance and supply chain management : Governance, ethics, and industry 5.0
A comprehensive analysis of digital platforms as the driving force of the modern economy, exploring their evolution, governance, and integration across financial and supply chain ecosystems. It presents a synthesis of theories, strategic models, and empirical insights to address the complexities of platform economies, making it an essential resource for scholars, policymakers, and industry practitioners. It is structured around core principles of digital platforms, including their definition, key features, and transformative impact on value creation. It delves into governance and ethical considerations, examining global regulatory frameworks and the emerging paradigms of Industry 5.0, where digital platforms intersect with economic, social, and environmental sustainability. The theoretical foundations are rooted in network effects, New Economic Geography, Platform Economics, Agency Theory, and Systems Theory, offering a robust analytical framework for understanding scalability, competition, and strategic decision-making in platform ecosystems. Two important areas -finance and supply chains-are explored in depth.
