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Genome Editing : Gene Therapy or Gene Optimization?
Genome editing technology is considered one of the most revolutionary techniques lately. The ability of modifying the human genome has been one of the biggest dreams for therapist for the reason that the genetic modification with exogenous DNA can be considered a problem solver for many diseases and disorders (genetic disorders), especially those with high risks and low survival rates, on this case, gene therapy appears as the tool to be used, with its many protocols and approaches. Gene therapy is based on delivering a therapeutic gene throw suitable vectors, which is most of the time-modified viruses to carry the therapeutic genes to the target cells and so on providing the functional copy of the defective gene.
Fundamentals of Space Medicine
Topics discussed in this book include: adaptation of sensory-motor, cardio-vascular, bone, and muscle systems to the microgravity of spaceflight; psychological and sociological issues of living in a confined, isolated, and stressful environment; operational space medicine, such as crew selection, training and in-flight health monitoring, countermeasures and support; results of space biology experiments on individual cells, plants, and animal models; and the impact of long-duration missions such as the human mission to Mars. The author also provides a detailed description of how to fly a space experiment, based on his own experience with research projects conducted onboard Salyut-7, Mir, Spacelab, and the Space Shuttle. Now is the time to look at the future of human spaceflight and what comes next. The future human exploration of Mars captures the imagination of both the public and the scientific community. Many physiological, psychological, operational, and scientific issues need to be solved before the first crew can explore the enigmatic Red Planet. This book also identifies the showstoppers that can be foreseen and what we need to learn to fully understand the implications and risks of such a mission.
Fundamentals of clinical research : Bridging medicine, statistics and operations
The scope of clinical research is to evaluate the effect of a treatment on the evolution of a disease in the human species.The treatment can be pharmacological, surgical, psychological/behavioral or organizational/logistic. The disease, intended as an impairment of a state of well-being or a condition capable of provoking such impairment over time, can be universally accepted as such (e.g. a cancer or a bone fracture) or perceived as such only by limited groups of individuals in a given cultural context (e.g. hair loss or weight gain). The course of the disease that ones wishes to change can be the one with no intervention or, more frequently, the one observed with the available treatment. The evaluation of the effect of a treatment on the course of a disease is a lengthy process, which progresses in increasingly complex stages.
Fundamentals of anatomy and physiology of speech, language, and hearing
Each topic is explored in bullet-point form with augmentative paragraph information, in-depth box features, and detailed illustrations. High-resolution Anatomage virtual dissection table figures derived from real cadavers offer an unparalleled glimpse into the anatomical structures of the human body, featuring true-to-life colors and an impressive level of detail. Topics explored include respiration, phonation, articulation, swallowing, resonance, hearing, balance, neuroanatomy, and neurophysiology.
Freehand figure drawing for illustrators
In Freehand Figure Drawing for Illustrators, artist and instructor David H. Ross provides an alternative solution, showing you how to master freehand figure drawing without visual reference by using a modern twist on the classic technique of blocking out the human figure in mannequin form. Step-by-step lessons guide illustrators from basic poses (standing, running, jumping) to extreme motions (throwing punches, high kicking). For on-the-go artists, Freehand Figure Drawing for Illustrators allows you complete freedom to bring your figures to life at any time
Foundations of augmented cognition ; 3rd International Conference, FAC 2007, Held as Part of HCI International 2007, Beijing, China, July 22-27, 2007, Proceedings
These papers address the latest research and development efforts and highlight the human aspects of design and use of computing systems. This volume contains papers in the thematic area of Augmented Cognition.
Forging New Frontiers : Fuzzy Pioneers I
The 2005 BISC International Special Event-BISCSE’05 " FORGING THE FRONTIERS" was held in the University of California, Berkeley, “WHERE FUZZY LOGIC BEGAN, from November 3 – 6, 2005. The successful applications of fuzzy logic and it’s rapid growth suggest that the impact of fuzzy logic will be felt increasingly in coming years. Fuzzy logic is likely to play an especially important role in science and engineering, but eventually its influence may extend much farther. In many ways, fuzzy logic represents a significant paradigm shift in the aims of computing - a shift which reflects the fact that the human mind, unlike present day computers, possesses a remarkable ability to store and process information which is pervasively imprecise, uncertain and lacking in categoricity.
Forensic pathology reviews ; Vol. 3
Maintaining the high quality achieved in earlier volumes, leading national and international forensic pathologists provide in Forensic Pathology Reviews, Volume 3 evidence-based accounts of special topics of current interest from various fields of forensic pathology and death-scene investigation. The authors offer cutting-edge insights into the medicolegal investigation of bodies found in water, the forensic aspects of the human immunodeficiency virus (HIV)-1 infection of the central nervous system, deaths in a head-down position, and forensic bitemark analysis. Additional chapters address taphonomic changes in human bodies during the early postmortem interval, arrhythmogenic ventricular dysplasia that produces sudden death in young people, the postmortem diagnosis of death in anaphylaxis, and iatrogenic deaths. The forensic aspects of suicide, murder-suicide, and suicide trends in the United States are also discussed, along with the evaluation of fatal pulmonary thromboembolism and the use of radiology in medicolegal investigations. A comprehensive, up-to-date review of the international literature is given for each chapter. Evidence-based and state-of-the-art, Forensic Pathology Reviews, Volume 3 synthesizes the practical advances made in a variety of important subspecialties of forensic pathology, demonstrating how the latest medical and scientific advances are being applied to solve current problems of high interest to forensic pathologists today.
Food Safety Culture : Creating a Behavior-Based Food Safety Management System
Food safety awareness is at an all time high, new and emerging threats to the food supply are being recognized, and consumers are eating more and more meals prepared outside of the home. Accordingly, retail and foodservice establishments, as well as food producers at all levels of the food production chain, have a growing responsibility to ensure that proper food safety and sanitation practices are followed, thereby, safeguarding the health of their guests and customers. Achieving food safety success in this changing environment requires going beyond traditional training, testing, and inspectional approaches to managing risks. It requires a better understanding of organizational culture and the human dimensions of food safety. To improve the food safety performance of a retail or foodservice establishment, an organization with thousands of employees, or a local community, you must change the way people do things. You must change their behavior. In fact, simply put, food safety equals behavior.
Fluconazole : Pharmacology, clinical uses and health effects
Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. In this book, the authors present current research in the study of the pharmacology, clinical uses and health effects of fluconazole. Topics discussed include the utilization of fluconazole in adult intensive care units; the use of fluconazole in veterinary species and a description of variances from the human experience as well as findings in veterinary species which may have applicability in human medicine; common clinical uses and in vitro activity features on fluconazole; and the discovery and development of medically-important antifungal agents, particularly the azole derivatives and the development of fluconazole and its clinical applications.
First Responder's Guide to Abnormal Psychology : Applications for Police, Firefighters and Rescue Personnel
Natural disasters. Hostage situations. Terror attacks. During these and other emergency situations, first responders make split-second judgments: evaluating risks, identifying dangerous conditions, and—often the hardest job of all—attending to those distressed and disturbed by their ordeal. First Responder's Guide to Abnormal Psychology gives readers critical insights into the human impact of extreme trauma, and the various levels of mental impairment suffered by both victims and survivors. Renowned trauma experts William Dorfman and Lenore Walker give this book immediate relevance through the use of real-life examples from a wide range of crisis situations. They have also deliberately minimized research citations within the text for greater readability.
Eye Tracking Methodology : Theory and Practice
Despite the availability of cheap, fast, accurate and usable eye trackers, there is still little information available on how to develop, implement and use these systems. This second edition of Andrew Duchowski’s successful guide to these systems contains significant additional material on the topic and fills this gap in the market with this accessible and comprehensive introduction. Opening with useful background information, including an introduction to the human visual system and key issues in visual perception and eye movement, the second part surveys eye-tracking devices and provides a detailed introduction to the technical requirements necessary for installing a system and developing an application program. The book focuses on video-based, corneal-reflection eye trackers – the most widely available and affordable type of system, before closing with a look at a number of interesting and challenging applications in human factors, collaborative systems, virtual reality, marketing and advertising.
Exercises in Environmental Physics
Exercises in Environmental Physics covers the essential topics in university courses in environmental physics including: Energy and the environment / Fluid mechanics / Evapotranspiration, soil physics and groundwater hydrology / Pollution / Ocean and atmospheric physics / The planet in space This is the first book specifically devoted to exercises on the application of physics to describe the environment including the human impact. It is a valuable tool for students to develop skills in the manipulation of physical concepts and methods while learning environmental science. The exercises are drawn from the author's teaching experience and the need for stimulating practice problems in various environmental physics courses. A chapter on mathematical methods used in the book supplements the material.
Essentials of pharmacodynamics and drug action
Provides a comprehensive exploration of the dynamic field of pharmacology and its fundamental principles. It delves into the intricate interactions between drugs and the human body, focusing on pharmacokinetics, which explains the dynamics of drug actions in the body, and pharmacodynamics, which uncovers the mechanisms through which drugs exert their effects. The book also emphasizes the crucial aspects of therapeutics and gene-based therapy, shedding light on modern approaches to disease treatment.
Ergonomics and Health Aspects of Work with Computers ; International Conference, EHAWC 2007, Held as Part of HCI International 2007, Beijing, China, July 22-27, Proceedings
This book address the latest research and development efforts and highlight the human aspects of design and use of computing systems. It cover the entire field of Human-Computer Interaction, addressing major - vances in knowledge and effective use of computers in a variety of application areas. This volume contains thematic area of Ergonomics and Health Aspects of Work with Computers, addressing the following major topics:Health and Well Being in the Working Environment, Ergonomics and Design
Entrepreneurship and innovation education : Frameworks and tools
This book is a compilation of tools, techniques and frameworks for use in the field of entrepreneurship and innovation (E&I) education. Developed and honed over the past two decades, these teaching approaches are combined with well-versed practical insight. As professors know all too well, the human brain cannot articulate more than three or four dimensions of a problem without the aid of what could be referred to as checklists for thinking: frameworks (visual or otherwise) that help students think in terms of multiple variables affecting a problem.
Engineering psychology and cognitive ergonomics ; 7th International Conference, EPCE 2007, Held as Part of HCI International 2007, Beijing, China, July 22-27, 2007, Proceedings
This book address the latest research and development efforts and highlight the human aspects of design and use of computing systems. It cover the entire field of Human-Computer Interaction, addressing major - vances in knowledge and effective use of computers in a variety of application areas. This volume contains papers in the thematic area of En- neering Psychology and Cognitive Ergonomics, addressing the following major topics: Cognitive and Affective Issues in User Interface Design, Cognitive Workload and Human Performance, Cognitive Modeling and Measuring, Safety Critical Applications and Systems
Engineering human computer interaction and interactive systems ; Joint Working Conferences EHCI-DSVIS 2004, Hamburg, Germany, July 11-13, 2004, Revised Selected Papers
As its name suggests, the EHCI-DSVIS conference has been a special event, merging two different, although overlapping, research communities: EHCI (Engineering for Human-Computer Interaction) is a conference organized by the IFIP 2.7/13.4 working group, started in 1974 and held every three years since 1989. The group’s activity is the scientific investigation of the relationships among the human factors in computing and software engineering. DSVIS (Design, Specification and Verification of Interactive Systems) is an annual conference started in 1994, and dedicated to the use of formal methods for the design of interactive systems. Of course these two research domains have a lot in common, and are informed by each other’s results.
Encyclopedia of Human Nutrition
Provides updated information on the foundations of nutrition science, along with the biology and functions of vitamins and other essential nutrients present in the human diet. The book's content offers a modern understanding of the links between diet and health effects, including diseases of recognized nutritional etiology. This overview of the genetic and molecular aspects of nutrient-health interrelationships includes important content on topics like nutrigenomics, metabolomics and the microbiome. In addition, the book provides global context, particularly on the issue of food production, sustainability and climate change.
Elder care center = دار ﻟﺮﻋﺎﻳﺔ اﻟﻤﺴﻨﻴﻦ وﻓﻖ ﻣﻌﻴﺎر جديد
مركز رعاية المسنين، قبل كل شيء، هو ملاذ للراحة والطمأنينة. إنه مكان يلتقي فيه كبار السن بالأطفال، حيث يمتزج عمق التصميم المعماري بالبعد الإنساني، محولاً اليتم إلى جسر للتواصل، ومخففاً من وطأة الوحدة. يعزز المشروع مفهوم الاندماج، انطلاقاً من الإيمان بأن الشيخوخة لا تعني الانعزال عن العالم، بل تعني التفاعل معه بكرامة وشمولية. Elder Care center above all, a space of comfort and reassurance. It’s a place where the elderly meet with children, where the architectural depth merges with the human dimension. turning orphan hood into a bridge for connection and filling the void of loneliness. the project strengthens the concept of integration, operating from the belief that aging doesn’t mean detachment from the world, but rather a dignified and inclusive engagement with it.
