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Drug utilization research : Methods and applications
Drug Utilization Research (DUR) is a discipline which combines aspects of pharmacotherapy, epidemiology, and health services research into an interdisciplinary set of methods for analyzing and assessing the prescribing, dispensing and consumption of medicines. It combines both qualitative and quantitative approaches to facilitate the safe and effective use of pharmaceuticals. Drug Utilization Research: Methods and Applications provides a comprehensive introduction to this discipline, prepared by an international team of authors with broad experience in numerous fields. Now reorganized and updated to reflect the latest research and global challenges, it is an indispensable resource for understanding the use of pharmaceuticals.
Drug Targets in Kinetoplastid Parasites
The book contains 12 chapters contributed by eminent scientists working in this field. The articles deal mainly with two aspects: visual identification of targets and identification of therapeutic agents.Several targets like kDNA replication machinery, purine salvage pathway, purine and pyrimidine biosynthetic pathway, histone deacetylase, DNA topoisomerases, membrane transporter proteins, glycoproteins and glycolipids are discussed in this book. Since current treatments for kinetoplastid parasitic diseases are far from ideal, there is an urgent and genuine need to develop newer compounds as antiparasitic drug candidates. Therefore evelopment of some lead compounds against these parasites as well as drug resistance are also included in this book. Moreover the vast amount of information generated after publication of the "Trytrip" genome sequence now makes possible several new approaches for target identification and discovery of therapeutic agents. This book is an outcome of the contributions of many scientists working in this important area.
Drug residues in animal products
The use of veterinary drugs in food-producing animals has the potential to generate residues in animal derived products (meat, milk, eggs and honey) and poses a health hazard to the consumer. There are many factors influencing the occurrence of residues in animal products such as drug's properties and their pharmacokinetic characteristics, physicochemical or biological processes of animals and their products. The most likely reason for drug residues might be due to improper drug usage and failure to keep the withdrawal period...
Drug interactions in infectious diseases : Mechanisms and models of drug interactions
Provides a comprehensive review of basic clinical pharmacology with a focus on metabolism and transporter-mediated drug interactions. The chapters address materials that cannot be retrieved easily in the medical literature, including materials focused on the complex interrelationship of acute infection, inflammation, and the risk of drug interactions in the Drug-Cytokine chapter. The Food-Drug and Herb-Drug interactions chapters remain definitive resources. A new chapter on in vitro modeling of drug interactions is included along with updates on design and data analysis of clinical drug interaction studies. Authoritative discussion of models for regulatory decision-making on drug-drug interactions provides the necessary framework to aid antimicrobial drug development. This concise review of the mechanisms and models of drug interactions provides important insights to health care practitioners as well as scientists in drug development
Drug interactions in infectious diseases : Antimicrobial drug interactions
Delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included. Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.
Drug and Biological Development : From Molecule to Product and Beyond
Drug and Biological Development: From Molecule to Product and Beyond offers a complete discussion of product development in the pharmaceutical and biotechnology industries from discovery to product launch, continuing through life cycle management. The book is organized for optimal usefulness in the education and training of health care professionals. The text's narrative descriptions are enhanced by real-life examples, illustrations, controversies in industry, and references. Dr. Ronald Evens and his contributors are industry and research experts in a variety of disciplines.
Drug and Alcohol Abuse : A Clinical Guide to Diagnosis and Treatment
Gives professionals and students across the health and mental health disciplines a working knowledge of drug-related pathology, beginning with pharmacology, drug mechanisms, and genetic factors. This title features clinical/emergency orientation suited to both chronic misuse and acute situations.
Drop acid
Our most respected scientific literature is bursting with evidence that elevated uric acid levels lie at the root of many pervasive health conditions, but mainstream medicine for the most part remains unaware of this connection. This is especially alarming because many people don’t know they are suffering from sky-high levels, putting them at risk for developing or exacerbating potentially life-threatening illnesses.
Driving smart medical diagnosis through AI-powered technologies and applications
Driving Smart Medical Diagnosis Through AI-Powered Technologies and Applications serves as a solution in this era of transformative healthcare and addresses these challenges head-on. It unravels the complexities surrounding the implementation of AI in healthcare, offering in-depth discussions on the latest breakthroughs. From unraveling the mysteries of AI-driven cataract detection to exploring the implications of decentralized mammography classification, the book is a valuable resource that equips scholars with the knowledge to navigate this innovative landscape.
Doing Cross-Cultural Research : Ethical and Methodological Perspectives
Conducting cross-cultural research is rife with methodological, ethical and moral challenges. Researchers are challenged with many issues in carrying out their research with people in cross-cultural arenas. In this book, I attempt to bring together salient issues for the conduct of culturally appropriate research. The task of undertaking cross-cultural research can present researchers with unique opportunities, and yet dilemmas. The book will provide some thought-provoking points so that our research may proceed relatively well and yet ethical in our approach. The subject of the book is on the ethical, methodological, political understanding and practical procedures in undertaking cross-cultural research.
DNA damage detection : Methods and protocols
Explores techniques in DNA damage analysis, important not only for understanding cellular health after exposure to genotoxic agents but also for assessing cellular ability of genome maintenance. The book explores traditional DNA damage measurement methods, as well as modern fluorescence-based analysis and high throughput automatic analysis methods. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Disorders due to addiction and its therapy in Syria
Addiction is a broad and important concept that has a lot of bad consequences, the goal of our research is to talk at an overview of all its types in order to raise public health awareness, addiction is not limited to narcotic substances, but until there is a behavioral type that includes getting used to harmful habits, we as pharmacists will focus on drug dependence and its mechanism, which many patients suffer from its disorders...
Disease in Wild Animals : Investigation and Management
Wildlife diseases have become increasingly important recently due to their effect upon human health, veterinary medicine, wildlife, and conservation biology. Gary Wobeser's successful book from 1994 has been completely updated and enlarged in a new second edition. An in-depth overview of the available techniques for the investigation and management of disease in free-ranging animals is provided. The subjects are illustrated with examples drawn from around the world, with emphasis on the special requirements involved in working with wild animals. Techniques are assessed critically with regard to their efficacy and effectiveness.
Disasters : Core Concepts and Ethical Theories
Examines disasters from a multidisciplinary perspective. Justification of actions in the face of disasters requires recourse both to conceptual analysis and ethical traditions. Part 1 of the book contains chapters on how disasters are conceptualized in different academic disciplines relevant to disasters. Part 2 has chapters on how ethical issues that arise in relation to disasters can be addressed from a number of fundamental normative approaches in moral and political philosophy. This book sets the stage for more focused normative debates given that no one book can be completely comprehensive. Providing analysis of core concepts, and with real-world relevance, this book should be of interest to disaster scholars and researchers, those working in ethics and political philosophy, as well as policy makers, humanitarian actors and intergovernmental organizations.
Disability, Health and Human Development
Introduces the human development model to define disability and map its links with health and wellbeing, based on Sen’s capability approach. The author uses panel survey data with internationally comparable questions on disability for Ethiopia, Malawi, Tanzania and Uganda. It presents evidence on the prevalence of disability and its strong and consistent association with multidimensional poverty, mortality, economic insecurity and deprivations in education, morbidity and employment. It shows that disability needs to be considered from multiple angles including aging, gender, health and poverty. Ultimately, this study makes a call for inclusion and prevention interventions as solutions to the deprivations associated with impairments and health conditions.
DiPiro’s pharmacotherapy : A pathophysiologic approach
It is this in-depth knowledge of pharmacotherapy, combined with the clinical experience gained through postgraduate training in direct patient care practice, that allows the pharmacist to be the "medication therapy expert" on the healthcare team and to proactively address medication-related problems.It is provides knowledge necessary to prevent, identify, and manage disease and medication-related problems
Digitization of healthcare data using blockchain
Gives a detailed description of the integration of blockchain technology for Electronic Health Records and provides the research challenges to consider in various disciplines such as supply chain, drug discovery, and data management. he aim of the book is to investigate the concepts of blockchain technology and its association with the recent development and advancements in the medical field. Moreover, it focuses on the integration of workflow strategies like NLP, and AI which could be adopted for boosting the clinical documentation and electronic healthcare records (EHR) usage by bringing down the physician EHR data entry. Also, the book covers the usage of smart contracts for securing patient records. Digitization of Healthcare Data Using Blockchain presents the practical implementations that deal with developing a web framework for building highly usable healthcare applications, a simple blockchain-powered EHR system.
Digital twin technology : fundamentals and applications
Provides an in-depth examination of digital twin technology to take you on an enthralling trip across the intersection of the virtual and real worlds. It explores the transformational impact of digital twins, from their roots in engineering to their widespread applications in manufacturing, health care, and other areas. Real-world case studies highlight the practical benefits, while potential hazards are addressed wisely. This book is your guide to comprehending the present and visualizing a future where digital twins transform innovation, efficiency, and connectedness in our increasingly complicated world. Begin this illuminating trip and embrace the possibilities that exist at the intersection of the physical and digital worlds.
Digital Mammography ; 9th International Workshop, IWDM 2008 Tucson, AZ, USA, July 20-23, 2008 Proceedings
This volume (5116) of Springer’s Lecture Notes in Computer Science contains the th proceedings of the 9 International Workshop on Digital Mammography (IWDM) which was held July 20 – 23, 2008 in Tucson, AZ in the USA.
Digital Imaging and Communications in Medicine (DICOM) : A Practical Introduction and Survival Guide
This is the first Digital Imaging and Communications in Medicine (DICOM) book to introduce this complex imaging standard from a very practical point of view. It is aimed at a broad audience of radiologists, clinical administrators, information technologists, and digital medicine practitioners.
