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Modern avenues in metal-nucleic acid chemistry

Provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues. More recently, also as a consequence of the advent of supramolecular chemistry, advancements in nanochemistry, and new bio-analytical methods, novel aspects of this field have emerged. MILS-25 gives a state-of-the-art account on the present state of research in this field, addressing, among others, porous materials, non-covalent interactions, stimuli-responsive bioconjugates, DNA-templated metal arrays and nanoclusters, genotyping, guanine quadruplexes, and riboswitches.

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Modern aspects of pharmaceutical quality assurance : developing and proposing application models, SOPs, practical audit systems for pharma industry

Aims to develop a tool that will substantially decrease the number of Inspectional Observations and Warning letters, thus eliminating Import Alerts and Consent Decree. This book targets the Pharmaceutical Industry and students of Pharmaceutical Quality Assurance so they can get in hand-ready consolidated information on Pharmaceutical Quality guidelines, Quality metrics, and implementation of simplified SOP guidelines, plant layouts to implement Quality metrics for Pharmaceutical Manufacturing systems in tablets, capsules, liquid orals, and semi-solid dosage forms.

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Modern Aspects of Electrochemistry ; Vol. 41

The 41st volume in this series covers a range of topics that touch on issues of potential interest to those working in electrochemistry-related fields. … Overall, this text contains a diverse collection of topics that would be of varying degrees of interest to the broader electrochemistry community. More likely, the individual chapters would be most valued by specialists working in these areas."As the most recent volume of a successful series established 1954 and carefully continued this book provides a timely collection of four review papers covering widely distributed aspects of electrochemistry in representative contributions.

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Modern Aspects of Electrochemistry ; Vol. 39

This volume of Modern Aspects covers a wide spread of topics presented in an authoritative, informative and instructive manner by some internationally renowned specialists. Professors Politzer and Dr. Murray provide a comprehensive description of the various theoretical treatments of solute-solvent interactions, including ion-solvent interactions. Both continuum and discrete molecular models for the solvent molecules are discussed, including Monte Carlo and molecular dynamics simulations. The advantages and drawbacks of the resulting models and computational approaches are discussed and the impressive progress made in predicting the properties of molecular and ionic solutions is surveyed.

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Modern architecture and climate design before air conditioning

explores how leading architects of the twentieth century incorporated climate-mediating strategies into their designs, and shows how regional approaches to climate adaptability were essential to the development of modern architecture. Focusing on the period surrounding World War II'before fossil-fuel powered air-conditioning became widely available'Daniel Barber brings to light a vibrant and dynamic architectural discussion involving design, materials, and shading systems as means of interior climate control. He looks at projects by well-known architects such as Richard Neutra, Le Corbusier, Lúcio Costa, Mies van der Rohe, and Skidmore, Owings, and Merrill, and the work of climate-focused architects such as MMM Roberto, Olgyay and Olgyay, and Cliff May. Drawing on the editorial projects of James Marston Fitch, Elizabeth Gordon, and others, he demonstrates how images and diagrams produced by architects helped conceptualize climate knowledge, alongside the work of meteorologists, physicists, engineers, and social scientists. Barber describes how this novel type of environmental media catalyzed new ways of thinking about climate and architectural design.

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Modern Actuarial Risk Theory : Using R

"The book gives a comprehensive survey of non-life insurance mathematics. … Originally written for use with the actuarial science programs at the Universities of Amsterdam and Leuven, it is now in use at many other universities as well as for the non-academic actuarial education program organized by the Dutch Actuarial Society. The methods presented can not only be used in non-life insurance, but also in other branches of actuarial science, as well as in actuarial practice. (Pavel Stoynov, Zentralblatt MATH, Vol. 1148, 2008). This book gives an introduction to non-life insurance mathematics. … Throughout the book, the software R is used for the implementation of the techniques presented. One finds also many exercises with hints for their solution in an appendix.

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Models in Software Engineering ; Workshops and Symposia at MoDELS 2007, Nashville, TN, USA, September 30 - October 5, 2007, Reports and Revised Selected Papers

This book constitutes the thoroughly refereed post-workshop proceedings of 10 internationl workshops and 2 symposia held as satellite events of the 10th International Conference on Model Driven Engineering Languages and Systems, MoDELS 2007, in Nashville, TN, USA, in September/October 2007 (see LNCS 4735).The 29 revised full papers were carefully selected for inclusion in the book and are presented along with a doctoral and an educators' symposium section. The papers are organized in topical sections representing the various workshops: aspect-oriented modeling (AOM 2007), language engineering (ATEM2007), model driven development of advanced user interfaces (MDDAUI 2007), model size metrics (MSM 2007).

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Models in Cooperative Game Theory : Crisp, Fuzzy, and Multi-Choice Games

This book investigates the classical model of cooperative games with transfer­ able utility (TU-games) and models in which the players have the possibility to cooperate partially, namely fuzzy and multichoice games. In a crisp game the agents are either fully involved or not involved at all in cooperation with some other agents, while in a fuzzy game players are allowed to cooperate with infinitely many different participation levels, varying from non-cooperation to full cooperation. A multichoice game describes an intermediate case in which each player may have a fixed number of activity levels. Part I of the book is devoted to the most developed model in the theory of cooperative games, that of a classical TU-game with crisp coalitions, which we refer to as crisp game along the book. It presents basic notions, solutions concepts and classes of cooperative crisp games in such a way that allows the reader to use this part as a reference toolbox when studying the corresponding concepts from the theory of fuzzy games (Part II) and from the theory of multichoice games (Part III).

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Models for computer aided tolerancing in design and manufacturing ; Selected conference papers from the 9th CIRP International Seminar on Computer-aided tolerancing, held at Arizona State University, Tempe, Arizona, USA, 10-12 April, 2005

Computer Aided Tolerancing (CAT) is an important topic in any field of design and production where parts move relative to one another and/or are assembled together. Geometric variations from specified dimensions and form always occur when parts are manufactured. Improvements in production systems can cause the amounts of the variations to become smaller, but their presence does not disappear. To shorten the time from concept to market of a product, it has been increasingly important to take clearances and the tolerancing of manufacturing variations into consideration right from the beginning, at the stage of design. Hence, geometric models are defined that represent both the complete array of geometric variations possible during manufacture and also the influence of geometry on the function of individual parts and on assemblies of them.

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Models and methods for management science

Introduces systems science as an entry point to present a basic introduction to research models and methods in management science (operation research). This textbook selects the classic quantitative models and methods as well as rich cases and detailed examples, which are suitable for students with a certain management and economics knowledge for further study, and helps to develop the abilities of using the basic models in real life

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Models and Algorithms for Global Optimization : Essays Dedicated to Antanas Žilinskas on the Occasion of His 60th Birthday

The research of Antanas Žilinskas has focused on developing models for global optimization, implementing and investigating the corresponding algorithms, and applying those algorithms to practical problems. This volume, dedicated to Professor Žilinskas on the occasion of his 60th birthday, contains new survey papers in which leading researchers from the field present various models and algorithms for solving global optimization problems. 

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Modelling, Computation and Optimization in Information Systems and Management Sciences ; 2nd International Conference MCO 2008, Metz, France - Luxembourg, September 8-10, 2008. Proceedings

This book constitutes the refereed proceedings of the Second International Conference MCO 2008, Metz, France, September 2008.The 65 revised full papers presented were carefully reviewed and selected from 160 submissions. The papers are organized in topical sections on optimization and decision making; data mining theory, systems and applications; computer vision and image processing; computer communications and networks; optimization and search techniques for security, reliability, trust.

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Modelling, Analysis and Optimization of Biosystems

Mathematical models in biology and medicine cannot be based on natural laws as it is the case with physics and chemistry. This is due to the fact that biological and medical processes are concerned with living organisms. Mathematical models, however, can be used as a language by which certain aspects of biological or medical processes can be expressed. In general, several mathematical models can be designed in order to describe a biological or medical process and there is no unique criterion which model gives the best description. This book presents several of these models and shows applications of them to different biological and medical problems. The book shows that operations research expertise is necessary in respect to modeling, analysis and optimization of biosystems.

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Modelling of Powder Die Compaction

In particular, the book presents a number of case studies that have been developed to test compaction models. Full details of the data required for input to compaction models of these case studies is given, together with a survey of the techniques used to generate the data. Details are also given of methods to produce and assess components for validation of die compaction models. The inclusion of information on case studies then provides a reference for the testing and validation of compaction models.

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Modelling in Mechanical Engineering and Mechatronics : Towards Autonomous Intelligent Software Models

Modelling in Mechanical Engineering and Mechatronics presents a model-centred approach focusing on distributed development and use of autonomous intelligent software models, particularly the efficiency of the models, and their interaction and integration into distributed autonomous intelligent systems. In order to systematise the available knowledge, a domain ontology is presented; a subset of which is used to create a modelling theory based on knowledge and experience in the areas of software engineering, mechanical engineering and mechatronics. This holistic view of modelling explains the purpose and the essence of modelling, as well as the benefits that are to be expected. It discusses the relations to other branches of engineering and science and as a result, it demonstrates strategies, methods and tools for unleashing the full power of modelling.

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Modelling in Mathematical Programming : Methodology and Techniques

This book provides basic tools for learning how to model in mathematical programming, from models without much complexity to complex system models. It presents a unique methodology for the building of an integral mathematical model, as well as new techniques that help build under own criteria. It allows readers to structure models from the elements and variables to the constraints, a basic modelling guide for any system with a new scheme of variables, a classification of constraints and also a set of rules to model specifications stated as logical propositions, helping to better understand models already existing in the literature. It also presents the modelling of all possible objectives that may arise in optimization problems regarding the variables values. The book is structured to guide the reader in an orderly manner, learning of the components that the methodology establishes in an optimization problem. The system includes the elements, which are all the actors that participate in the system, decision activities that occur in the system, calculations based on the decision activities, specifications such as regulations, impositions or actions of defined value and objective criterion, which guides the resolution of the system.

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Modelling Critical and Catastrophic Phenomena in Geoscience : A Statistical Physics Approach

This book presents a broad survey of models for critical and catastrophic phenomena in the geosciences, with strong emphasis on earthquakes. It assumes the perspective of statistical physics, which provides the theoretical frame for dealing with complex systems in general. This volume addresses graduate students wishing to specialize in the field and researchers working or interested in the field having a background in the physics, geosciences or applied mathematics.

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Modelling community structure in freshwater ecosystems

"The book presents approaches and methodologies for predicting the structure and diversity of key aquatic communities (namely diatoms, benthic macroinvertebrates and fish), under natural conditions and under man-made disturbance. Such an approach will make it possible to: 1) set up procedures for robust and sensitive ecosystem evaluation, based on the prediction of the excepted community structure; 2) model community structure in disturbed ecosystems, taking into account all the relevant ecological variables; 3) test ecosystem sensitivity to natural and anthropic disturbance; and 4) explore specific actions to be taken for the restoration of ecosystem integrity."--Jacket.

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Modelling Autonomic Communications Environments ; 3rd IEEE International Workshop, MACE 2008, Samos Island, Greece, September 22-26, 2008. Proceedings

Research and development of autonomics have come a long way, and we are delighted to present the proceedings of the 3rd IEEE International Workshop on Modelling Autonomic Communications Environments (MACE 2008).Asin the last two years, this workshopwasheld aspart of Manweek, the International Week on Management of Networks and Services, which took place on the lovely Island of Samos in Greece .MACE started as anexperimentin2006,andcreatedasmallcommunitythat nowfnds it self attracted backeachyearby afeeling ofexcitement-thatthere is something new going on. Certainly, MACE is not as shiny or practiced as other well-known conferences and workshops, but we consider this a feature of the workshopitself.

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Modelling and Simulation : Exploring Dynamic System Behaviour

Modelling and Simulation: Exploring Dynamic System Behaviour provides the reader with a balanced and integrated presentation of the modelling and simulation activity for both Discrete Event Dynamic Systems (DEDS) and Continuous Time Dynamic Systems (CTDS). This book presents the fundamentals necessary to understand the many important facets of the modeling and simulation methodology.

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