Page 16
Page 16
Epigenetic Drug Discovery
This broad view of epigenetic approaches in drug discovery combines methods and strategies with individual targets, including new and largely unexplored ones such as sirtuins and methyl-lysine reader proteins. Presented in three parts - Introduction to Epigenetics, General Aspects and Methodologies, and Epigenetic Target Classes - it covers everything any drug researcher would need in order to know about targeting epigenetic mechanisms of disease.
Environmental Policy Instruments for Conserving Global Biodiversity
If you can believe, all things are possible to him who believes. —Mark 9:23 The current, unprecedented loss of global biodiversity as a result of anthropo genic interference in the world's ecosystems is affecting human well-being across the globe with increasing severity. It therefore represents a major chal lenge in international environmental policymaking. With the Convention on Biological Diversity (CBD), the community of states has recognized the in creasing importance of preserving biodiversity. Given the extensive context of biodiversity loss and preservation, this study focuses on two issues, which are at the center of the public discussion regarding the objectives of conservation and the sustainable use of biodiversity, and that are addressed by specific policy instruments. The first issue is the regulation of cross-border trade in genetic information and genetic resources. Here, the question is whether the commercial use of genetic information derived from bio diversity can create incentives for its preservation. The second issue involves the conservation of biodiversity through the protection of ecologically valuable eco systems from human use.
Entry Inhibitors in HIV Therapy
The introductory chapters of this book present an overview of entry inhibitors, review current knowledge of how Env mediates entry, and discuss the challenge of genetic diversity in this region of the viral genome. Subsequent chapters feature current information on individual classes of entry inhibitors that target each step of the virus entry pathway, from attachment to membrane fusion. There is an emphasis on the complex determinants of entry inhibitor susceptibility, resistance mechanisms, the need for clinical phenotyping, and how these issues create new challenges for antiretroviral therapy. Encouraging pre-clinical studies of entry inhibitors as microbicidesare also discussed. The final chapters highlight the current status of entry inhibitors in clinical studies, the major milestone achieved with FDA approval of enfuvirtide, and review drug development, past and present.
Entertainment computing – ICEC 2007 ; 6th International Conference, Shanghai, China, September 15-17, 2007, Proceedings
This book are organized in topical sections on augmented, virtual and mixed reality, computer games, image processing, mesh and modeling, digital storytelling and interactive systems, sound, music and creative environments, video processing, rendering, computer animation and networks, game based interfaces, as well as robots and cyber pets.
Enhancing Smallholder Farmers' Access to Seed of Improved Legume Varieties Through Multi-stakeholder Platforms : Learning from the TLIII project Experiences in sub-Saharan Africa and South Asia
This book shares the experiences of Tropical Legumes III (TLIII) project in facilitating access to seed of improved legume varieties to smallholder farmers through innovation platforms. It highlights practices and guiding principles implemented in eight developing countries of sub-Saharan Africa and South Asia. This book details key processes that respective teams employed to create an innovation space that delivers seed, other inputs, knowledge and financial services to agricultural communities and most importantly, the underserved farmers in remote areas of the drylands
Engineering Evolutionary Intelligent Systems
This edited volume 'Engineering Evolutionary Intelligent Systems' deals with the theoretical and methodological aspects, as well as various evolutionary algorithm applications to many real world problems originating from science, technology, business or commerce.
Energy Metabolism and Obesity : Research and Clinical Applications
Elucidate the most important aspects of genetic background, neuropeptide secretion and action, neuronal pathways, adipokines, gut hormones, and environmental influences (physical activity, pharmacologic agents, and surgical alteration of the gastrointestinal tract), as well as the complex interactions among them.
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine
This is the most authoritative and wide-ranging reference yet assembled on Functional Genomics (the systematic analysis and identification of genes and their function) and Proteomics (the study of the complex structures and functions of proteins) in the rapidly expanding field of Molecular Medicine. The two-volume reference work offers a comprehensive overview of the terms, topics and issues in both molecular biology and molecular medicine, with particular emphasis placed on the molecular causes of diseases. It provides up-to-the minute information about developments in the field, including pharmacogenetics and pharmacoproteomics, gene regulation and gene therapy. The Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine is an invaluable tool for clinical scientists in academia and industry, and all who need fast and user-friendly access to key information in this dynamically developing field.
Encyclopedia of Human Nutrition
Provides updated information on the foundations of nutrition science, along with the biology and functions of vitamins and other essential nutrients present in the human diet. The book's content offers a modern understanding of the links between diet and health effects, including diseases of recognized nutritional etiology. This overview of the genetic and molecular aspects of nutrient-health interrelationships includes important content on topics like nutrigenomics, metabolomics and the microbiome. In addition, the book provides global context, particularly on the issue of food production, sustainability and climate change.
Encyclopedia of Genetics, Genomics, Proteomics and Informatics
It includes about 56% more words than the 1,392-page 2nd edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. Cross-references among entries are expanded. The statements are supported by references; more than 14,000 journal papers and more than 3,000 books are listed. The book includes ~1,800 current databases and web servers. Retractions and corrigenda are pointed out.It covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, patents, etc. Similar integrated information is not available in textbooks or on the Internet. The journal reviews called it the best, high-quality resource for researchers, instructors and students of basic and applied biology, as well as for physicians and lawyers or even for interested laymen because of the clarity of presentation.
Encyclopedia of Entomology
Brings together the expertise of more than 450 distinguished entomologists from 40 countries to provide a worldwide overview of insects and their close relatives. Combining the basic science of an introductory text with accurate, comprehensive detail, the Encyclopedia is a reliable first source of reference for students and working professionals. Coverage includes insect classification, behavior, ecology, genetics and evolution, physiology, and management, and references to relevant literature. All the major arthropod groups are addressed, along with many important families and species. The Encyclopedia places special emphasis on insect relationships with people, medical entomology, biological control and insect pathology. This important work also presents biographical sketches of hundreds of entomologists who have made important contributions to the discipline since its origin. The new Second Edition is fully indexed, and includes more than 120 color plates.The four-volume Encyclopedia of Entomology is a handy desk-top reference for entomologists, and a valuable source of information for scientists and students in agronomy, botany, disease biology, ecology, evolutionary biology, forestry, genetics, horticulture, parasitology, toxicology, and zoology. It is also available as an easily accessible, fully searchable online reference.
Emergent Computation : Emphasizing Bioinformatics
Emergent Computation is concerned with recent applications of Mathematical Linguistics or Automata Theory. This subject has a primary focus upon ""Bioinformatics"" (the Genome and arising interest in the Proteome), but the closing chapter also examines applications in Biology, Medicine, Anthropology, etc. The book is composed of an organized examination of DNA, RNA, and the assembly of amino acids into proteins. Rather than examine these areas from a purely mathematical viewpoint (that excludes much of the biochemical reality), the author uses scientific papers written mostly by biochemists based upon their laboratory observations. Thus while DNA may exist in its double stranded form, triple stranded forms are not excluded. Similarly, while bases exist in Watson-Crick complements, mismatched bases and abasic pairs are not excluded, nor are Hoogsteen bonds. Just as there are four bases naturally found in DNA, the existence of additional bases is not ignored, nor amino acids in addition to the usual complement of 20. Can there be more than ""64"" possible codons? RNA is examined from the point of view of Nussinov plots.
Embedded Robotics : Mobile Robot Design and Applications with Embedded Systems
This book presents a unique examination of mobile robots and embedded systems, from introductory to intermediate level. It is structured in three parts, dealing with Embedded Systems (hardware and software design, actuators, sensors, PID control, multitasking), Mobile Robot Design (driving, balancing, walking, and flying robots), and Mobile Robot Applications (mapping, robot soccer, genetic algorithms, neural networks, behavior-based systems, and simulation).
Embedded Robotics : Mobile Robot Design and Applications with Embedded Systems
The EyeBot controller and mobile robots have evolved over more than a decade. This book gives an in-depth introduction to embedded systems and autonomous mobile robots, using the EyeBot controller (EyeCon) and the EyeBot mobile robot family as application examples. This book combines teaching and research material and can be used for courses in Embedded Systems as well as in Robotics and Automation.
Embedded robotics : From mobile robots to autonomous vehicles with Raspberry Pi and Arduino
Presents a unique examination of mobile robots and autonomous vehicles using embedded systems, from introductory to advanced level. It is structured in four parts, dealing with Embedded Systems (processors, sensors, actuators, control, multitasking and communication), Robot Hardware (driving and walking robots, autonomous boats and planes, as well as robot manipulators), Robot Software (localization, navigation, image processing and automotive systems), and Artificial Intelligence (neural networks, genetic algorithms and deep learning). The book is organized for ease of use, with numerous figures, photographs, and worked example programs. The book is written as a text for courses in computer science, computer engineering, IT, electronics engineering, and mechatronics, as well as a guide for robot hobbyists and researchers.
Electrical Diseases of the Heart : Genetics, Mechanisms, Treatment, Prevention
Electrical Diseases of the Heart is a thorough clinical reference on the current status of cardiac electrophysiological disease,emphasizing common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology, and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science.
Efficient Screening Techniques to Identify Mutants with TR4 Resistance in Banana : Protocols
The Joint FAO/IAEA Centre of Nuclear Techniques in Food and Agriculture implemented a Coordinated Research Project (CRP) ‘Efficient Screening Techniques to Identify Mutants with Disease Resistance for Coffee and Banana” (2015-2020). This CRP brought together experts from Asia, Europe and Africa in addition to experts of the Joint FAO/IAEA Centre to develop resistance against TR4 through mutation-assisted breeding. Induced mutagenesis is particularly attractive in case of banana since most cultivated bananas are seedless, thus hampering conventional cross breeding
Efficient Learning Machines : Theories, Concepts, and Applications for Engineers and System Designers
Machine learning techniques provide cost-effective alternatives to traditional methods for extracting underlying relationships between information and data and for predicting future events by processing existing information to train models. Efficient Learning Machines explores the major topics of machine learning, including knowledge discovery, classifications, genetic algorithms, neural networking, kernel methods, and biologically-inspired techniques.
Effector-triggered immunity : methods and protocols
Presents a collection of protocols to study effector-triggered immunity (ETI) in both plants and animals from eminent groups in the field. Cover topics such as genetic manipulation of plant and animal pathogens, host cells, and the analysis of key host responses; and techniques used for the analysis of inflammasome activation, cell death pathways, and mitochondria damage in response to pathogens. All of these topics cover a broad spectrum of immunological, biochemical, cell biological, and structural biology approaches to examine ETI.
Economic Loss Caused by Genetically Modified Organisms : Liability and Redress for the Adventitious Presence of GMOs in Non-GM Crops
The cultivation of genetically modified (GM) crops in the EU may lead to cases, in which traditional agricultural products contain detectable traces of GMOs. On the one hand, such admixture may result from inadequate application of segregation measures by farmers. On the other hand, as agriculture is an open process that does not allow the complete isolation of individual fields, a certain degree of admixture between neighbouring crops is unavoidable in practice. The presence of GMOs in traditional products may lead to their devaluation, which would entail an economic damage to the producer of
