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Antisense RNA Technology
The following project aims to introducing the technology of RNA Antisense as new therapy for many diseases. Antisense RNA: In molecular biology, the strand complementary to a coding sequence of a nucleic acid. Antisense DNA is the non-coding strand complementary to the coding strand in double-stranded DNA. The antisense strand serves as the template for messenger RNA (mRNA) synthesis. This synthesized nucleic acid is termed an "anti-sense" oligonucleotide (AON) because its base sequence is complementary to the gene's messenger RNA (mRNA), which is called the "sense" sequence (so that a sense segment of mRNA " 5'-AAGGUC-3' " would be blocked by the anti-sense mRNA segment " 3'-UUCCAG-5' ").
Antisense RNA Design, Delivery, and Analysis
This volume gathers a variety of models, delivery systems, and approaches that can be used to assess RNA technology for exploiting antisense as a therapeutic intervention. Beginning with a section on the design of antisense technology and their delivery, the book continues by covering model systems developed to evaluate efficacy, both in vivo and in vitro, as well as methods to evaluate preclinically the toxicity associated with these new potential drugs, and intellectual property considerations. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Antimicrobial Resistance and Implications for the Twenty-First Century
This new volume of the Emerging Infectious Diseases of the 21st Century series is a collection of chapters by leading world authorities on antimicrobial resistance of common, important bacterial, viral and fungal pathogens. This unique book should be in the possession of anyone interested in the field of infectious diseases, microbiology, infection control & public health. The chapters, which are written by reknown experts, provide a wealth of contemporary information on microbiology, molecular mechanisms, epidemiology, clinical relevance, treatment, and prevention
Anti-Inflammatory diet
An anti-inflammatory diet may serves as a complementary treatment for many conditions that worsen with chronic inflammation, and an anti-inflammatory diet focuses on fresh fruits and vegetables. Combine a variety of foods that are rich in nutrients, provide a range of antioxidants, and contain healthy fats. Such as fatty fish, green tea, berries, and special herbs such as curcumin, ginger, and licorice. ..
Anti-fragile ICT Systems
Introduces a novel approach to the design and operation of large ICT systems. It views the technical solutions and their stakeholders as complex adaptive systems and argues that traditional risk analyses cannot predict all future incidents with major impacts. To avoid unacceptable events, it is necessary to establish and operate anti-fragile ICT systems that limit the impact of all incidents, and which learn from small-impact incidents how to function increasingly well in changing environments. The book applies four design principles and one operational principle to achieve anti-fragility for different classes of incidents. It discusses how systems can achieve high availability, prevent malware epidemics, and detect anomalies. Analyses of Netflix’s media streaming solution, Norwegian telecom infrastructures, e-government platforms, and Numenta’s anomaly detection software show that cloud computing is essential to achieving anti-fragility for classes of events with negative impacts.
Antidepressants Beyond Depression, and Into Bacteria
Antidepressants are one of the most predominant drug groups in the pharmaceutical world, primary care units and the general public. Their original use was majorly for the treatment of depression along with other mental disorders. Today, antidepressant consume over 20% of the medical prescriptions and healthcare plans due to their recently discovered applications outside the psychiatry field. Due to the alarming rise of antibiotic resistance and the slow pace of new drug discovery, the world has been searching frantically for new or alternative drugs with antibacterial activity. Repurposing already FDA- approved drugs for uses that are off-label has become an important preposition in the pharmacy world due to its availability, low risk and low cost.
Anticoagulants and coronary artery disease
Blood thinners are medicines that help blood flow smoothly through your veins and arteries. There are two. The first is called anticoagulants (Warfarin, Heparin, Enoxaparin) and The second class of blood thinners is called antiplatelet (Aspirin, Ticagrelor , Clopidogrel). . Coronary arteries supply blood to the heart muscle. Coronary artery disorder or disease can have serious implications by reducing the flow of oxygen and nutrients to the heart muscle. This can lead to a heart attack and possibly death. Atherosclerosis. Medications to reduce the risk of blood clots, such as anticoagulants (including aspirin) and antiplatelet. , in particular aspirin, are effective in preventing platelet activation and thus thrombus formation and Clopidogrel is an inhibitor of platelet activation.
Antibiotics : Methods and protocols
Provides state-of-the-art and novel methods on antibiotic isolation and purification, identification of antimicrobial killing mechanisms, as well as methods for the analysis and detection of microbial responses and adaptation strategies. Antibiotics: Methods and Protocols, Second Edition, guides readers through updated and entirely new chapters on production and design, mode of action, and response and resistance. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Antibiotic users behavior in Syria between pharmacists and consumers
In an attempt to study antibiotic resistance in the syria, we studied the impact of consumer behavior On resistance. We conducted a study of pharmacists within a number(69) distributed in Damascus, and a study among consumers distributed among different regions, and the results are in the studies section.
Anthracycline Chemistry and Biology II : Mode of Action, Clinical Aspects and New Drugs
This series presents critical reviews of the present position and future trends in modern chemical research. It contains short and concise reports on chemistry, each written by the world renowned experts. The series is still valid and useful after five or ten years. More information as well as the electronic version of the whole content is available at: springerlink.com.
Anthracycline Chemistry and Biology I : Biological Occurence and Biosynthesis, Synthesis and Chemistry
"This book … covers many different aspects of the origin, chemistry, and biosynthesis of one of the oldest but most important classes of anticancer agents. … In summary, the book is nicely produced, very well edited, and should serve as a valuable source of information … . This book will serve as an inspiration for scientists and students in the areas of chemistry, drug discovery, and biological evaluation. It should be an essential addition to institutional library collections … ."
Antecedents of venture firms' internationalization : A conjoint analysis of international entrepreneurship in the net economy
With the continuing dispersion of the global digital network and performance improvements of information and communication technologies, resource-poor start-ups with online business models have emerged in large numbers. These firms are able to deploy their competitive advantages across their country borders early in their life-cycle and engage in international commerce at a fast pace. An increased immediacy between the firms and the globally accessible customer is observed. Julia Christofor’s study aims to analyze the conditions of the initial internationalization decision in the Net Economy. Based on Information Systems, International Entrepreneurship, and Entrepreneurship literature, factors, which constitute the internationalization propensity, are derived. The results of this study suggest that a holistic perspective including the founder, business model and the firm level should be considered when explaining the internationalization propensity of entrepreneurs.
Ant Colony Optimization and Swarm Intelligence ; 5th International Workshop, ANTS 2006, Brussels, Belgium, September 4-7, 2006, Proceedings
ANTS – The International Workshop on Ant Colony Optimization and Swarm Intelligence is now at its ?fth edition. The series started in 1998 with the - ganization of ANTS 1998. At that time the goal was to gather in a common meeting those researchers interested in ant colony optimization: more than 50 researchers from around the world joined for the ?rst time in Brussels, Belgium, to discuss ant colony optimization and swarm intelligence related research. A selectionofthebest paperspresentedatthe workshopwaspublished asa special issue of the Future Generation Computer Systems journal (Vol. 16, No. 8, 2000). Two years later, ANTS 2000, organized again in Brussels, attracted more than 70 participants. The 41 extended abstracts presented as talks or posters at the workshopwere collected in a booklet distributed to participants, and a selection of the best papers was published as a special section of the IEEE Transactions on Evolutionary Computation (Vol. 6, No. 4, 2002).
Anorexia nervosa and mood-enhancing foods
Anorexia nervosa (AN) is a serious mental illness characterized by failure to maintain normal weight and by overvalued ideas about the importance of body shape and weight. This study aims to discuss Anorexia nervosa and understand the pathophysiology to successfully fight this enigmatic illness and present the goal of the treatment for individuals with AN. The bi-directional influences between emotion and food consumption are discussed. Finally, we have searched in Future Directions and Treatment development of AN.
Anomaly Detection : Techniques and Applications
When information in the data warehouse is processed, it follows a definite pattern. An unexpected deviation in the data pattern from the usual behavior is called an anomaly. The anomaly in the data is also referred to as noise, outlier, spammer, deviations, novelties and exceptions. Identification of the rare items, events, observations, patterns which raise suspension by differing significantly from the majority of data is called anomaly detection. With progress in the technologies and the widespread use of data for the purpose for business the increase in the spams faced by the individuals and the companies are increasing day by day. This noisy data has boomed as a major problem in various areas such as Internet of Things, web service, Machine Learning, Artificial Intelligence, Deep learning, Image Processing, Cloud Computing, Audio processing, Video Processing, VoIP, Data Science, Wireless Sensor etc. Identifying the anomaly data and filtering them before processing is a major challenge for the data analyst. This anomaly is unavoidable in all areas of research. This book covers the techniques and algorithms for detecting the deviated data.
Annual bibliography of the history of the printed book and libraries ; Vol.31 : Publications of 2000 and additions from the preceding years
The Annual Bibliography of the History of the Printed Book and Libraries aims at recording articles of scholarly value which relate to the history of the printed book, to the history of arts, crafts, techniques and equipment, and of the economic social and cultural environment, involved in its production, distribution, conservation and description.
Animals in Our Midst : The Challenges of Co-existing with Animals in the Anthropocene
This book brings together authoritative voices in animal and environmental ethics, who address the many different facets of changing human-animal relationships in the Anthropocene. As we are living in complex times, the issue of how to establish meaningful relationships with other animals under Anthropocene conditions needs to be approached from a multitude of angles. This book offers the reader insight into the different discussions that exist around the topics of how we should understand animal agency, how we could take animal agency seriously in farms, urban areas and the wild, and what technologies are appropriate and morally desirable to use regarding animals. This book is of interest to both animal studies scholars and environmental ethics scholars, as well as to practitioners working with animals, such as wildlife managers, zookeepers, and conservation biologists.
Android smart health monitoring system
Recent years have witnessed an increasing interest in the application of machine learning to clinical informatics and healthcare system never forgetting that the data also states that half of the world's population uses mobile devices. Despite of the existence of tons of applications, algorithms, and systems, the achievement of prescribing proper food that is suitable for patient health case based on face health status, height, weight, daily calories etc.., wasn’t achieved yet because of the lack of knowledge in food therapy process. Our system provides the service of food suggestion based on the input that is inserted by the user in sign-up form which are (height, weight, age, etc….).
Android Essentials
Android Essentials is a no–frills, no–nonsense, code–centric run through the guts of application development on Google's Mobile OS. This book uses the development of a sample application to work through topics, focusing on giving developers the essential tools and examples required to make viable commercial applications work. Covering the entirety of the Android catalog in less than 150 pages is simply impossible. Instead, this book focuses on just four main topics: the application life cycle and OS integration, user interface, location–based services, and networking.
Anatomical Imaging : Towards a New Morphology
This book presents selected works of contemporary evolutionary morphologists and includes such topics as broad scale reconstructions of the brain and ear of dinosaurs, inference of locomotor habits from cancellous bone architecture in fossil primates, and a comparison of the independently evolved manipulating apparatuses in the lesser and giant pandas. Insight is provided into the application of modern noninvasive technologies, including digital imaging techniques and virtual 3D reconstruction, to the investigation of complex anatomical features and coherences. In combination with traditional methods, this allows for the formulation of improved hypotheses on coordinated function and evolution. The creation of virtual translucent specimens makes it possible to realize the age-old dream of the classical anatomists: looking through the skin into the inner organization of an organism. On full display here is the dramatic and promising impact that modern imaging techniques have on scientific progress in evolutionary morphology.
