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Percutaneous Tumor Ablation in Medical Radiology
Thermal ablation has become an integral part of oncology, especially in the field of interventional oncology. This very comprehensive book encompasses the different technologies employed in thermal ablation, its indications and the results achieved in various clinical conditions. The first part of the book clearly explains the basics of thermal ablative techniques such as laser-induced thermotherapy, radiofrequency ablation, microwave ablation, cryotherapy, and localized tumor therapy. The latest developments in the application of minimally invasive therapies in localized neoplastic disease are demonstrated. In the main part of the book, techniques of guiding the applicators to the target structures by use of different imaging tools such as ultrasound, computed tomography and magnetic resonance imaging are discussed.
Percutaneous Collagen Induction With Microneedling : A Step-by-Step Clinical Guide
Percutaneous Collagen Induction with Microneedling is a minimally invasive technique widely used to treat numerous dermatologic conditions such as facial and body scars, melasma, wrinkles, skin laxity, stretch marks, alopecies, vitiligo and scleroderma. Microneedling can also be used to optimize transdermal drug delivery for many substances. This technique uses modern microneedling devices containing multiple fine needles, typically 0.5 to 2.5 mm in length, which are mounted on a barrel and rolled onto the skin to create numerous perforations into the stratum corneum and the papillary dermis. These micro-wounds initiate the release of growth factors, triggering collagen and elastin formation, which results in dermal remodeling and skin resurfacing. This book provides a step-by-step approach to microneedling, based on the authors’ more than ten years of experience with the technique.
Penetration testing in the UK ; Proceedings of the geotechnology conference organized by the Institution of Civil Engineers and held in Birmingham on 6–8 July 1988
The geotechnical engineer needs to be aware of the advantages and problems of different tests for sites with different geological conditions. Interpreting the results of penetration tests is an essentially empirical activity and as such the engineer is required to understand standard equipment and procedures. This book provides crucial information about all these considerations and is a valuable textbook of current theory and practice.
Pediatric Orthopedics in Practice
The idea for this book originated from pediatricians who were frequently encountering patients with musculoskeletal problems and who, during a course in pediatric orthopaedics, expressed a wish for a book that would take into account the standpoint of the pediatrician, as well as those of the children and parents.This book also aims to stress the regional (rather than a systematic) subdivision of disorders. After all, a child does not come to the doctor’s office saying »I’m suffering from a growth disorder« or »I have a congenital condition«. Rather he or she will say »my back hurts« or »I have a stabbing pain in my knee«.
Pediatric ocular surface disease
Dedicated to pediatric ocular surface diseases. It provides an up-to-date and highly illustrated discussion of the pathophysiology, symptomatology and diagnostic and therapeutic strategies of these less commonly understood diseases, in a format that is readily absorbed by trainees and seasoned physicians alike. The aim of this book is to provide a practical and detailed understanding of ocular surface disease in the pediatric population,as many of these corneal conditions in children require unique therapeutic approaches and may have subtle presentations. Chapters will address key issues, such as dry eye disease, Steven Johnson Syndrome and neurotrophic keratitis, that can have a profound impact on children’s visual and social development.
Pediatric Neurogenic Bladder Dysfunction : Diagnosis, Treatment, Long-Term Follow-up
Pediatric Neurogenic Bladder Dysfunction ( Pediatric NBD) offers a leading international reference on the diagnostic and therapeutic approach to the pediatric patient with urinary problems due to spinal cord pathologies. It represents a unique guide for all the specialists involved in the management of this pathology. The contributors are international leading experts in clinical research and in surgical practice of this pathologic condition. All the aspects of NBD in children from the clinical and diagnostic evaluation to the pharmacological and surgical treatment are covered. Pediatric surgeons, pediatricians, general physicians and therapists will benefit from this clear, easy and up-to- date review of the diagnostic and therapeutic procedures adopted today.
Pediatric hematopoietic stem cell transplantation for pharmacists : The gold standard to practice
Addresses subjects such as stem cells and their differentiation mechanisms; aspects of embryonic and non-embryonic stem cells ; stem cell transplantation in pediatrics ; stem cell sources and related technical choices ; stem cell donors ; scheduling transplantations ; diseases and chemotherapy protocols that require stem cell transplantation ; stem cell homing ; engraftment and repopulation of stem cells in bone marrow; autologous stem cell transplantation in pediatrics ; allogeneic stem cell transplantation in pediatrics ; and indications for autologous and allogeneic pediatric stem cell transplantation. Further, it discusses pediatric graft-versus-host disease and the pharmacist ; antibacterial and antifungal prophylaxis ; detailed chemotherapy, conditioning and trials for pediatric stem cell transplantation ; conditioning granulocyte colony-stimulating factor (G-CSF) in pediatric stem cell transplantation ; analyzing prescriptions and programming a pediatric stem cell transplantation ; handling chemotherapy and adjuvant drugs for pediatric stem cell transplantation ; stem cell transplantation in children up to 1 year old ; and clinical pharmacy in pediatric stem cell transplantation.
Pediatric Dentistry
Provides dental practitioners and students with all the knowledge required in order to treat optimally the oral conditions encountered in children and adolescents and to offer appropriate guidance on subsequent oral health self-care. The use of sedation and anesthesia is then discussed, followed by detailed information on such key topics as tooth eruption and shedding, preventive and interceptive orthodontics, and control of dental caries. Restoration procedures and pulp treatment necessitated by dental caries, trauma and/or developmental anomalies are clearly described, with reference to relevant advances in dental technology and materials. Subsequent chapters focus on conditions compromising dental or general oral health in the pediatric age group, such as periodontal diseases, dental wear, dental anomalies, TMJ disorders, and soft tissue lesions.
Pediatric Allergy, Asthma and Immunology
Pediatric Allergy, Asthma and Immunology reflects the rapid progress in one of the most intriguing fields of medicine. The book offers state-of-the-art information on basic immunology, fetal-neonatal immunology, genetic and environmental predisposing factors, epidemiology and natural history of atopic diseases, and allergy diagnosis. Extensive coverage is devoted to skin conditions and food allergy, asthma, rhinitis, specific immunotherapy, eye disorders, sinusitis and secretory otitis media, drug allergies, and anaphylaxis. Fascinating chapters explore such topics as autoimmune diseases, primary immunodeficiencies, pediatric HIV infection, malnutrition and the immune system. Finally, a chapter on prevention of the atopic march indicates how effective early intervention may greatly decrease the upsurge in atopy.
Paths to the Emerging State in Asia and Africa
This book addresses the issue of how a country, which was incorporated into the world economy as a periphery, could make a transition to the emerging state, capable of undertaking the task of economic development and industrialization. It offers historical and contemporary case studies of transition, as well as the international background under which such a transition was successfully made (or delayed), by combining the approaches of economic history and development economics. Its aim is to identify relevant historical contexts, that is, the ‘initial conditions’ and internal and external forces which governed the transition. It also aims to understand what current low-income developing countries require for their transition. Three economic driving forces for the transition are identified. They are: (1) labor-intensive industrialization, which offers ample employment opportunities for labor force; (2) international trade, which facilitates efficient international division of labor; and (3) agricultural development, which improves food security by increasing supply of staple foods.
Pathology of the Human Placenta
Most obstetricians and pediatricians would agree that the examination of the placenta often helps to explain an abnormal neona tal outcome. As early as in 1892, Ballantyne wrote, A diseased foetus without its placenta is an imperfect specimen, and a description of a foetal malady, unless accompanied by a notice of the placental condition, is incomplete. Deductions drawn from such a case cannot be considered as conc- sive, for in the missing placenta or cord may have existed the cause of the disease and death. During intrauterine life the foetus, the membranes, the cord and the placenta form an organic whole, and disease of any part must react upon and affect the others. Similar thoughts were succinctly detailed in Price’s (1950) discussion of his concept of the prenatal biases as they affected twins. His contribution also admonishes us that placental study is a sine qua non for a more perfect understanding of fetal development. Despite all this understanding of the past and appreciation for plac- tal disease, great resistance still exists to perform the task of placental examination routinely. For many pathologists, therefore, the placenta has remained a mysterious organ.
Past and Present Water Column Anoxia
Contains papers partly based on presentations by 60 scientists attending a NATO Advanced Research Workshop on Past and Present Water Column Anoxia in Sevastopol, Ukraine. They address the entire range of oxygen-deficient conditions and reflect the complexity of the issues governing the formation and persistence of such conditions.
Particle Image Velocimetry : New Developments and Recent Applications
Particle Image Velocimetry (PIV) is a non-intrusive optical measurement technique which allows capturing several thousand velocity vectors within large flow fields instantaneously. Today, the PIV technique has spread widely and differentiated into many distinct applications, from micro flows over combustion to supersonic flows for both industrial needs and research. Over the past decade the measurement technique and the hard- and software have been improved continuously so that PIV has become a reliable and accurate method for "real life" investigations. Nevertheless there is still an ongoing process of improvements and extensions of the PIV technique towards 3D, time resolution, higher accuracy, measurements under harsh conditions and micro- and macroscales. This book gives a synopsis of the main results achieved during the EC-funded network PivNet 2 as well as a survey of the state-of-the-art of scientific research using PIV techniques in different fields of application.
Paris Climate Agreement : Beacon of Hope
Presents an Empirical Model of Global Climate developed by the authors and uses that model to show that global warming will likely remain below 2ºC, relative to preindustrial, throughout this century provided: a) both the unconditional and conditional Paris INDC commitments are followed; b) the emission reductions needed to achieve the Paris INDCs are carried forward to 2060 and beyond.
Parental Life Courses after Separation and Divorce in Europe
This book assembles landmark studies on divorce and separation in European countries, and how this affects the life of parents and children. It focuses on four major areas of post-separation lives, namely (1) economic conditions, (2) parent-child relationships, (3) parent and child well-being, and (4) health
Paediatric dentistry for the general dental practitioner
A comprehensive guide to the management of children and adolescents in general dental practice. A logical, evidence-based approach to oral health is adopted throughout. The commonly encountered oral and dental problems and their diagnosis and treatment are covered in detail, with particular attention to dental caries, dental trauma, developmental anomalies, periodontal problems, and soft tissue conditions. Up-to-date guidance is provided on history taking, dental examination, preventive strategies and advanced behaviour management. In addition the relevance of common medical conditions to dental management is discussed. The book is divided into four sections, each of which focusses on a specific age group, helping the reader to relate clinical issues to the different dental developmental stages. The readily understandable text is supported by many informative colour illustrations and diagrams.
P5 eHealth : An Agenda for the Health Technologies of the Future
Focuses on the development of a P5 eHealth, or better, a methodological resource for developing the health technologies of the future, based on patients’ personal characteristics and needs as the fundamental guidelines for design.
Oxytocin and related neuropsychiatric disorder
Oxytocin (OT), a hypothalamic neuropeptide involved in regulating the social behaviour of all vertebrates, has been proposed as a treatment for a number of neuropsychiatric disorders characterised by deficits in the social domain. Over the last few decades, advances focused on understanding the social effects of OT and its role in physiological conditions and brain diseases, e first recognized as a regulator of parturition and lactation which has recently gained attention for its ability to modulate social behaviors. here is mounting preclinical evidence that targeting the brain oxytocin system may provide that breakthrough. Substance use disorders are characterised by a viscous cycle of bingeing and intoxication, followed by withdrawal and negative affect, and finally preoccupation and anticipation that triggers relapse and further consumption.
Oxidative Stress in Aging : From Model Systems to Human Diseases
Oxidative Stress in Aging: From Model Systems to Human Diseases discusses the role of free radicals in aging in different animal models, as well as the relevance of free radicals on age-related diseases and pathological conditions in humans (following an introduction section of the basics and theory of free radicals). Human aging is a complex phenomenon - not everyone gets the same diseases and dies from the same cause. Accumulating reports implicate the connection between free radicals and various diseases and age-related pathological conditions. Although the causal relationships have not been established, it is necessary to discuss how free radicals are involved in each situation. In addition, the major interventions trials of antioxidant supplements in age-related disease, cancer and so forth are reviewed and discussed.
Oxidative Stress and Neuroprotection
This book deals with basic and clinical aspects of monoamine oxidase (MAO) subtypes A and B highlighting its importance in neurological and psychiatric diseases. Consequently the therapeutic actions of MAO-A and -B inhibitors in Parkinson’s disease (PK) and depression are the focus of several chapters. As MAO is the basis of the development of the "oxidative stress hypothesis" of PD, several chapters are devoted to iron and iron-induced oxidative stress in various experimental studies and clinical conditions. Based on these findings, new compounds have been developed which not only block MAO, but are in addition, either inhibitors of acetylcholine esterase or have iron chelating properties. The aspect of "preclinical" and "clinical" neuro protection as well as MAO neuroprotection are additional topics covered in this book. MAO, iron and neuroprotection are seen in the framework of general anti Parkinson’s therapy with chapters on levodopa, dopaminergic receptor agonists and clinical issues.
