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The High Energy Solar Corona : Waves, Eruptions, Particles
An outgrowth of a workshop held by the Community of European Solar Radio Astronomers (CESRA), this volume collects reviews on current research and perspectives on the variable solar corona.
The heparins : Basic and clinical aspects
Brings information on heparin, one of the world's most widely used drugs. The book describes the fascinating history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders. The structures of various heparins are illustrated, with their function as anticoagulants delineated. This comprehensive resource arms researchers and clinicians with a concise and practical source that will assist in biomedical research, medical practice, and in improving patient outcomes.
The Handbook of Nanomedicine
Nanomedicine is clinical medicine with the application of nanobiotechnology, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development and delivery of drugs. In The Handbook of Nanomedicine, Prof. Kewal K. Jain distills the voluminous literature relevant to the subject into one concise, comprehensive and easy-to-use guide. Beginning with the basics, the subject is developed to potential clinical applications, many of which are still at an experimental stage. Important components of nanomedicine such as nanodiagnostics and nanopharmaceuticals are covered extensively
The handbook of medicinal chemistry : Principles and practice
Draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies.
The Handbook of Contraception : A Guide for Practical Management
Provides a comprehensive review of contraception methods for all reproductive-aged women, including those who are young and healthy, postpartum, perimenopausal, adolescent, or who have a medical disease.
The Great Cholesterol Myth, Revised and Expanded : Why Lowering Your Cholesterol Won't Prevent Heart Disease--and the Statin-Free Plan that Will
Heart disease is the #1 killer. However, traditional heart disease protocols—with their emphasis on lowering cholesterol—have it all wrong. Emerging science is showing that cholesterol levels are a poor predictor of heart disease and that standard prescriptions for lowering it, such as ineffective low-fat/high-carb diets and serious, side-effect-causing statin drugs, obscure the real causes of heart disease. Even doctors at leading institutions have been misled for years based on creative reporting of research results from pharmaceutical companies intent on supporting the $31-billion-a-year cholesterol-lowering drug industry.
The Geospatial Web : How Geobrowsers, Social Software and the Web 2.0 are Shaping the Network Society
Summarizes the latest research on the Geospatial Web’s technical foundations, describes information services and collaborative tools built on top of geo-browsers, and investigates the environmental, social and economic impacts of geospatial applications. The role of contextual knowledge in shaping the emerging network society deserves particular attention. By integrating geospatial and semantic technology, such contextual knowledge can be extracted automatically – for example, when processing Web documents to identify relevant content for customized news services.
The Genesis of Fluid Mechanics, 1640-1780
Fluid Mechanics, as a scientific discipline in a modern sense, was established between the last third of the 17th century and the first half of the 18th one. This book analyses its genesis, following its evolution along two basic lines of research, which have been named the "problem of resistance" and the "problem of discharge". This approach highlights the existence of a remarkable experimental aspect in the aforementioned research lines, together with their link with problems of a practical nature, such as ballistics, hydraulics, fluid-using machines or naval theory. On the other hand, although previous studies usually present fluid mechanics from the point of view of mathematics, this is complemented here by an engineering viewpoint.
The GABA Receptors
Particular B emphasis is placed on describing the assembly, structure, and function of GABA B sites, the first heterodimeric G protein-coupled receptors identified in vivo. In addition, there are reports dealing with the subunit composition, trafficking, and pharmacological selectivity of GABA receptors.
The G Protein-Coupled Receptors Handbook
The G Protein-Coupled Receptors Handbook offers pharmacologists, biochemists, and neuroscientists an exhaustive review of the progress made in understanding how GPCRs are activated and regulated, key factors in exploiting GPCRs for drug development.
The future of management in an AI world : Redefining purpose and strategy in the fourth industrial revolution
Containing international insights from leading figures from the world of management and technology, this book addresses the big challenges facing organisations, including: Decision-making / Corporate strategy / People management and leadership / Organisational design
The Future of Financial Systems in the Digital Age : Perspectives from Europe and Japan
The increasing capacity of digital networks and computing power, together with the resulting connectivity and availability of “big data”, are impacting financial systems worldwide with rapidly advancing deep-learning algorithms and distributed ledger technologies. They transform the structure and performance of financial markets, the service proposition of financial products, the organization of payment systems, the business models of banks, insurance companies and other financial service providers, as well as the design of money supply regimes and central banking.
The future of capsule endoscopy from diagnostic to therapeutic experimental prototype capsule
Capsule endoscopy (CE) is indicated as a first-line clinical examination for the detection of small-bowel pathology, and there is an ever-growing drive for it to become a method for the screening of the entire gastrointestinal tract (GI). However systemic side effects of medications in the field of pharmacology is a huge obstacle for administration mainly in age related diseases therefore although CE's main function is diagnosis, our research for therapeutic capabilities has intensified to make therapeutic capsule endoscopy (TCE) a target within reach.
The future is now: an exploration of nanorobotics in medicine
Nanorobotics involves the design and development of tiny machines that can interact with biological systems at a cellular or molecular level, enabling precise and targeted tasks such as drug delivery, tissue repair, and disease detection. In this thesis we will discuss this emerging field of nanorobotics and its potential applications in medicine. The thesis provides an overview of the advantages and disadvantages of medical nanorobots, and describes the various types currently in development...
The future European energy system : Renewable energy, flexibility options and technological progress
This book analyzes the transition toward a low-carbon energy system in Europe under the aspects of flexibility and technological progress.
The fundamentals of clinical research : A universal guide for implementing good Clinical practice
Focuses on the practical application of good clinical practice (GCP) fundamentals and provides insight into roles and responsibilities included in planning, executing, and analyzing clinical trials.
The Fluorescence biomarker application in pharmacology and medicine
In developed countries, use in cancer for the first time is still one of the main causes of death. Early diagnostics has a great impact on higher chance for recovery. A good target for tumor progression diagnostics is liquid biopsy, which analyzes the circulating cancer markers in the body fluids, not like traditional biopsy in the tumor tissue, mainly thanks to its lesser invasiveness. This is important for patients who face many invasive procedures over the years...
The Evolution of Entrepreneurs - Fund-Raising Intentions : A Multiple Case Study of Financing Processes in New Ventures
Zooms in on potential influence factors triggering changes in entrepreneurs’ fund-raising intentions over time. The empirical analysis offers a novel model of task-specific entrepreneurial intentions and their cognitive antecedents in the context of investors’ demands for new venture legitimacy. The findings suggest two core recommendations for supporting growth-oriented fund-raising processes: a) to build legitimizing potential and b) to ensure sufficient financial scope for flexible adaptations throughout the financing struggle.
The Evaluation of Surrogate Endpoints
Both humanitarian and commercial considerations have spurred intensive search for methods to reduce the time and cost required to develop new therapies. The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental treatments or other interventions, is a general strategy that has stimulated both enthusiasm and skepticism. Surrogate endpoints are useful when they can be measured earlier, more conveniently, or more frequently than the "true" endpoints of primary interest.This book offers a balanced account on this controversial topic. The text presents major developments of the last couple of decades, together with a unified, meta-analytic framework within which surrogates can be evaluated from several angles. Methodological development is coupled with perspectives on various therapeutic areas. Academic views are juxtaposed with standpoints of scientists working in the biopharmaceutical industry as well as of colleagues from the regulatory authorities.
The etruscans and the history of dentistry : The golden smile through the ages
Offers a study of the construction and use of gold dental appliances in ancient Etruscan culture, and their place within the framework of a general history of dentistry, with special emphasis on appliances, from Bronze Age Mesopotamia and Egypt to modern Europe and the Americas.
