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The new Innovation of paracetamol
Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility (especially that a lot of drugs are in Class II and IV according to BCS (Biopharmaceutics Classification System) and these classes suffer from poor aqueous solubility and hence low bioavailability},dissolution rate, stability and mechanical properties of APIs and excipients...
The new histories of international criminal law : retrials
Has considerable traction in global politics, and much of its legitimacy is embedded in apparently 'axiomatic' historical truths. This innovative edited collection brings together some of the world's leading international lawyers with a very clear mandate in mind: to re-evaluate ('retry') the dominant historiographical tradition in the field of international criminal law.
The NeuroProcessor : An integrated interface to biological neural networks
This book presents the Neuroprocessor, a novel computational neuronal interface device implemented in VLSI technology. In addition to neuronal signals acquisition, it can process the data, generate stimuli and transmit the data over wireless channels, while using minimum electric energy.
The NeurIPS '18 Competition : From Machine Learning to Intelligent Conversations
This volume presents the results of the Neural Information Processing Systems Competition track at the 2018 NeurIPS conference. The competition follows the same format as the 2017 competition track for NIPS. Out of 21 submitted proposals, eight competition proposals were selected, spanning the area of Robotics, Health, Computer Vision, Natural Language Processing, Systems and Physics. Competitions have become an integral part of advancing state-of-the-art in artificial intelligence (AI). They exhibit one important difference to benchmarks: Competitions test a system end-to-end rather than evaluating only a single component; they assess the practicability of an algorithmic solution in addition to assessing feasibility.
The Network(ed) Economy : The Nature, Adoption and Diffusion of Communication Standards
In an increasingly globalized and networked world modern communication channels and new electronic media standards are constantly changing traditional interaction patterns of humans and even machines. Communication-based interaction is of pivotal economic importance and the availability of generally accepted electronic communication standards is essential in order to decrease communication-related transaction costs.This book combines the theories of diffusion and network effects and presents a new goods classification model to explore the dissemination of IT and e-business standards. On this basis it designs two applications that support and improve firms' electronic interlaced communication by means of automation and standardization effects.
The Morality of Business : A Profession for Human Wealthcare
That business is benevolent, positive, and honorable might seem a difficult argument given the hostility among intellectuals, academics, artists and pundits towards this essentially benevolent profession. In this thought-provoking book, The Morality of Business: A Profession for Human Wealthcare, Machan argues that business, like medicine, enhances human life, and that it is indeed a thoroughly decent profession for people to choose to enter, in order to best serve the worthy goal of promoting all around prosperity. He goes beyond the utilitarian case, that business serves society quite well, to contend that caring for one's own economic well being is prudent, that enhancing the wealth of one's household is a proper objective, and to serve clients in the capacity of managing their wealth successfully is every bit as honorable as serving patients with their health needs. The result is a positive statement, in the tradition of Adam Smith and David Hume, addressing some of the most controversial topics of today, including job "security," outsourcing, and government regulation.
The Moral, Social, and Commercial Imperatives of Genetic Testing and Screening : The Australian Case
This is a dynamic book that successfully combines global and local thinking with regard to an emerging technology that will contribute to the expansion of proteomics and pharmacogenomics, the science of tailored healthcare and treatments. Genetic testing and screening will change the way people understand health, diagnostic knowledge, illness but also crime, databases and private information, paternity, and self-knowledge. In addition to giving individuals the opportunity to think differently about their well-being, it installs a new taxonomy in terms of illness, because its probabilistic effects will introduce a new narrative in the health discourse of 21st century society. While in the past people could be classified as being healthy or sick, now, through genetic testing and screening, adults can be classified as being healthy, predisposed to an illness, probably at risk, at risk, or carriers of certain risks. The effects of this taxonomy do not remain confined to the individual who is tested but extends to an entire family, as genetic knowledge is family knowledge. But the technology of genetic testing and screening installs a second dramatic register in the prenatal phase when cells and embryos are tested and subsequently altered in order to hit targets of perfection.
The Metabolic Syndrome and Obesity
The Metabolic Syndrome and Obesity presents an up-to-date survey of the current scientific understanding of obesity and the metabolic syndrome, as well as an overview of the most significant changes to the field over the past 30 years. By first presenting a historical context for overweight, the book drives home the point that obesity is by no means simply a contemporary problem, and its continued existence means that we neither understand it, nor have developed effective therapies. The Metabolic Syndrome and Obesity is a comprehensive reference for the treatment of obesity in two parts. Part I, The Problem, examines the entire scope of the obesity epidemic, including epidemiology and history, costs of treatment, pathology, clinical types, age-related issues, and general health risks. Part II, The Solutions, describes several treatment options including diet, behavior modification, exercise, pharmacological treatment, and surgery. This volume is a thorough reference for obesity and the metabolic syndrome and offers an in-depth assessment of the problem and its myriad potential treatment options.
The Mathematica GuideBook for Numerics
Mathematica is today's most advanced technical computing system, featuring a rich programming environment, two-and three-dimensional graphics capabilities and hundreds of sophisticated, powerful programming and mathematical functions using state-of-the-art algorithms. Combined with a user-friendly interface and a complete mathematical typesetting system, Mathematica offers an intuitive, easy-to-handle environment of great power and utility.The available types of arithmetic (machine, high-precision, and interval) are introduced, discussed, and put to use. Fundamental numerical operations, such as compiling programs, fast Fourier transforms, minimization, numerical solution of equations, ordinary/partial differential equations are analyzed in detail and are applied to a large number of examples in the main text and solutions to the exercises.
The Machines of Leonardo Da Vinci and Franz Reuleaux : Kinematics of Machines from the Renaissance to the 20th Century
This book is about the evolution of these machines and the inv- tors and engineers who created them from the early Renaissance to the early 20th century. I have chosen two personalities who are icons of these two machine ages, Leonardo da Vinci [1452–1519] and Franz Reuleaux [1829– 1905], recognizing both the cadre of machine designers who in?uenced them as well as those who were in?uenced by the accomplishments of these two engineers. A major thesis of this book is that the evolution of machine design methodology, from the intuitive methods of the workshop to the math-based, engineering science analysis and synthesis of modern industrial design, was of equal achievement as the creation of the marvelous machines themselves. In the past two decades there has been increasing interest in rational me- ods of design from topology and optimization theories to genetic algorithms. In the teaching of design at the novitiate level, the importance of design - cles and iteration is emphasized. Yet often the historical background for e- lution of machine design is minimal or missing.
The Lebanese financial crisis and it’s impact on Syrian Bank
Lebanon is now facing a deep financial crisis, and commercial banks face the worse liquidity stress in the country’s history. Researches done till now do not correlate other factors to each other and to the crisis. Those factors are mainly: banking activities and decisions, compliance, political issues, economic factors, as well as crisis and “black swans”. As Macroeconomic and financial factors may combine supporting economic development and so the Sustainable Development Goals (SDGs) set by the United Nations for a better and safer future for society, the significance of this study is that, by defining and analysing the fragility factors will assist to develop an effective and efficient early banking crisis warning system and developing a financial innovation framework which contributes to societies’ well-being.
The Japanese Banking Crisis
Provides a readable narrative of the bubbles and the banking crisis Japan experienced during the two decades between the late 1980s and the early 2000s.
The Invisible Hand : Economic Thought Yesterday and Today
The economies of the European Union are today highly integrated. Constitutive part of this high degree of integration is the euro which unites most of the Member States within thee uro-zone. In order to ensure prosperity and stabilityofthis Union in the spirit of the European Stability and Growth Pact, economic policies in both the Union and its Member States need to be monitored and co-ordinated appropriately. This applies in particular also because of the enlargement process which adds a further dimension to the continuous challenge of having to deal with different economic policy concepts and traditions in our Union. Understanding the economic and sociopolitical debates in the individual Member States of the Union and elsewhere requires a solid knowledge not only of the economic but also of the social and historical background of these debates. In economics, more than in the natural sciences, human norms and conflicts play a central role in addition to logical relationships and empirical findings. Therefore, looking only at economic formulae and empirical facts will not be enough. Most economic textbooks, especially from the Anglo-Saxon area, tend to c- centrate more on the technically correct and often model-based presentation of their subject-matter than on its socio-political background. However, in view of the significance of economic reality for every citizen in Europe, it is also important to reach those who have not obtained a university degree in economics.
The information society : Innovation, Legitimacy, ethics and democracy ; Proceedings of the Conference "Information society : Governance, ethics and social consequences", University of Namur, Belgium, 22-23 May 2006
The IFIP series publishes state-of-the-art results in the sciences and technologies of information and communication. The principal aim of the IFIP series is to encourage education and the dissemination and exchange of information about all aspects of computing.
The Impact of The Macroeconomic Variable on Saudi Arabia Stock Market from (2005 – 2019)
The study aim to examine the relationship between macroeconomic variables and the Saudi Arabia stock market over the period (2005 to 2019). The dependent variable used in this study are Ratios of public debt to GDP (D/GDP), Average per capita income (APCI), and Interest Rate, Gold volume and Oil Price, Gross domestic product and the independent variable is the market index “Tadawul All Share index (TASI)”. In the results we could not find a linear equation because P-value was bigger than ALFA in the NOVA test, and the reason is mentioned in the study.
The Impact of Nutrition and Statins on Cardiovascular Diseases
The Impact of Nutrition and Statins on Cardiovascular Diseases presents a summary of the background information and published research on the role of food in inhibiting the development of cardiovascular diseases. Provides insights on the origin of cardiovascular diseases, an analysis of statin therapy, their side effects, and the role of dietary intervention as an alternative solution to preventing cardiovascular diseases. It focuses on the efficacy of nutrition and statins to address inflammation and inhibit the onset of disease, while also providing nutrition information and suggested dietary interventions.
The Impact of Macroeconomic Variables on Stock Prices: The Syrian Case
Aims to find out and examine the relationship between stock price and the macroeconomics variables. The monthly data of eight years ranges from 1st January 2011 to December 31th 2019 was used for this research study. Cointegration test was used in order to determine if there is a long relationship between stock price and both exchange rate and inflation rate in the long run. Also, we used Vector Error Correction Model (VECM) to determine if there is a relationship between stock price and the macroeconomics variables in short run, the following conclusion were reached : 1- There is a relationship between stock prices, inflation rates and exchange rates in the long run. / 2- There is a relationship between stock prices and exchange rates in short run
The Impact of Food Bioactives on Health : In vitro and ex vivo models
Describes in vitro and ex vivo models that can be employed to investigate effects of digested food products on the GIT, or specific components thereof. Many such models exist and include, for example, those used to study digestion and fermentation in the small and large intestine, to investigate absorption (e.g. Ussing chamber, epithelial cell systems), and to research the immune and enteroendocrine responses (e.g. macrophages, dendritic cells, co-cultures). In each case, these respective assays and models are discussed, and tips and tricks concerning their proper use are given. The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest. The book highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated, and highlights the strengths and weaknesses of the various assays. It is also an important resource for under-graduate students in the ‘food and health’ arena.
The Impact of Digital Technologies on Public Health in Developed and Developing Countries ; 18th International Conference, ICOST 2020, Hammamet, Tunisia, June 24–26, 2020, Proceedings
The objective of this work is to detect Alzheimer’s disease using Magnetic Resonance Imaging. For this, we use a three-dimensional densenet-121 architecture.
The Immune Synapse as a Novel Target for Therapy
The immune synapse can be compared to a molecular machine that controls T cell activation when getting in contact with an antigen-presenting cell (APC). The immune synapse is involved in the transfer of information across the T cell–APC junction. It plays an essential role in the control and nature of the immune response.In recent years several approaches have been developed to reprogram the immune response by targeting molecules involved in the immune synapse. Monoclonal antibodies, such as those targeting the lymphocyte co-receptor, costimulatory and adhesion molecules (CD3, CD4, CD40L, CTLA4-Ig, LFA-1), or altered peptide ligands have been shown capable of inducing immune tolerance in transplantation, autoimmunity and allergy. This volume discusses the progress in the field, from basic science to clinical trials, and the major mechanisms involved. It is of interest to clinicians and researchers working in this area.
