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Endovascular Aneurysm Repair : From Bench to Bed
Endovascular procedures have a tremendous impact upon modern patient care. This book summarizes covered stent-graft applications in the experimental and clinical settings. Excellent illustrations document the acute and chronic behavior of stent-grafts within the vascular system including diagnostic imaging, histologic work-up and schematic drawings. A large amount of experience on intravascular ultrasound-based repair of aortic pathologies is presented. Physicians interested in the endovascular field will find this book a very stimulating resource.
Endocrinology : Basic and Clinical Principles
For this new edition of Conn & Melmed's Endocrinology: Basic and Clinical Principles, a panel of distinguished scientists and clinicians has completely rewritten every chapter to reflect the latest advances in our understanding of the endocrine system. Maintaining the original goal of the first edition to integrate the basic science of endocrinology with its physiological and clinical principles, the authors have succinctly summarized in 450 pages the latest findings on hormone secretion and hormone action, as well as all of the most recent insights into the physiology and pathophysiology of hormonal disorders. Coverage extends across the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human diseases-with much increased coverage of diabetes and metabolism. Highlights include cutting-edge discussions of appetite disorders, obesity, reproductive failure, control of thyroid function, hormone action in humans and the lower species, and the mechanisms subserving hormone secretion.
Elwyn Simons : A Search for Origins
Summarizes the current state of knowledge in many aspects of primate and human evolution that have been studied by Simons and his colleagues and places it in a broader paleontological and historical perspective.A Search for Origins contains the results of new research and reviews of many of the critical issues in primate and human paleontology during the last half of the twentieth century as well as other aspects of African paleontology, geology, and primate conservation.The chapters include a wide range of important new works that are valuable contributions to the field of physical anthropology and are certain to be widely cited and used in teaching. The authors of this text are an extremely distinguished group of international authorities on all aspects of primate evolution, human evolution, and primate behavior.
Electronic Irradiation of Foods : An Introduction to the Technology
Electronic Irradiation of Foods describes all the key aspects of electron accelerator technology in detail. It emphasizes the physical science and technology aspects of food irradiation using machine sources of ionizing radiation. The book provides significant technical depth for interested workers and present descriptive, introductory material that should help demystify technology for businessmen to make informed choices regarding important investments decisions.Introductory chapters summarize the effects of ionizing radiation on biological organisms and the organic compounds comprising foods, and give an overview of the food irradiation process. Subsequent chapters cover the details of the electron beam and x-ray energy deposition, electron accelerator technologies, beam scanning systems, material handling systems, shielding design, and process control considerations. Important appendices cover radiation dosimetry, induced radioactivity, and ozone generation.
Electromagnetic Aquametry : Electromagnetic wave interaction with water and moist substances
This book covers all aspects of Electromagnetic Aquametry. It summarizes the wide area of metrology and its applications in electromagnetic sensing of moist materials. The physical properties of water in various degrees of binding interacting with electromagnetic fields is presented by model systems. The book describes measurement methods and sensors in the frequency domain, TDR-techniques for environmental problems, methods and sensors for quality assessment of biological substances, and nuclear magnetic resonance techniques
Electrodiagnosis of Retinal Disease
Soon it will be time for me to retire from my position as professor of o- thalmology in the Department of Ophthalmology, Nagoya University School of Medicine. I have therefore decided to summarize my expe- ence of more than 30 years of studies on the clinical electrophysiology of vision. These studies were performed in our department through the hard work and good ideas of many co-workers,and the chapters of this book cover the rationale and results of our studies.
Economic Analysis of Information System Investment in Banking Industry
Explains in reahty, examines theoretically, and analyzes statistically information system investment in the banking industry with regard to the process of the information technology revolution. This kind of comprehensive research on the banking industry is the first in the world. It could be seen as an application study for Japanese financial deregulation after 1997. However, our project, the Workshop of Information System Investment, is a theoretical research venture, consisting originally, when it began in 1994, of economists and computer scientists. It aimed to measure the effect of com puter hardware and software on the modern economy, based on the microdata of each firm, and to extend the frontiers of economic science. It was, coin- dentally, the time when this project began full-scale operation, in July 1997, that the voluntary closure of Yamaichi Securities was decided. The failure of the Hokkaido Takushoku Bank was disclosed in November of the same year, and the breakdown, temporary nationalization, buying out, and mergers of several banks succeeded one another. Our research therefore suddenly got into the social spotlight on the application stage. Part I is the first history and strategic guidelines of information systems in the banking industry. Part II summarizes the economic analyses of informa tion system investment in the United States, Europe, and Japan. These parts are foundations for the statistical analyses in Part III.
Earth Observation with CHAMP : Results from Three Years in Orbit
In the summer of 2000 the German geo-research satellite CHAMP was launched into orbit. Its innovative payload arrangement and the low initial orbit allow CHAMP to simultaneously collect and almost continuously analyse precise data relating to gravity and magnetic fields at low altitude. In addition, CHAMP also measures the neutral atmosphere and ionosphere using GPS techniques. Three years after launch, more than 200 CHAMP investigators and co-investigators from all over the world met at the GeoForschungsZentrum in Potsdam to present and discuss the results derived from the extensive data sets of the mission. The main outcome of this expert meeting is summarized in this volume. The book offers a comprehensive insight into the present status of the exploitation of CHAMP data for Earth system research and practical applications in geodesy, geophysics and meteorology.
Dynamics of Railway Bridges
Provides a comprehensive survey of the dynamic stresses in railway bridges under moving vehicles and summarizes important theoretical and experimental results which has been obtained from various research programs dealing with European railway bridges.
Dynamics of Complex Intracontinental Basins : The Central European Basin System
This book documents how researchers from different geo-scientific disciplines have jointly analysed the structural, thermal, and sedimentary evolution as well as fluid dynamics of a complex sedimentary basin system which has experienced a variety of activation and reactivation impulses as well as intense salt tectonics. In this book we have summarized our geological, geophysical and geochemical understanding of some of the most important processes affecting sedimentary basins in general and our view on the evolution of one of the largest, best explored and most complex continental sedimentary basins on Earth: The Central European Basin System.
Drugs in Ophthalmology
This drug handbook is divided into two sections: Alphabetical Listing of Drugs Entries in this section are listed by generic name. Information for each drug is arranged in a consistent format for easy reference. Summary of Anti-infectives This section summarizes the common doses of antibiotics, antifungals, and antivirals. For each drug, the dose for each route of administration is included.
Drug development for rare diseases
A disease is defined as rare if the prevalence is fewer than 200,000 in the United States. It is estimated that there are more than 7,000 rare diseases, which collectively affect 30 million Americans or 10% of the US population. This diverse and complex disease area poses challenges for patients, caregivers, regulators, drug developers, and other stakeholders. This book is proposed to give an overview of the common issues facing rare disease drug developers, summarize challenges specific to clinical development in small populations, discuss drug development strategies in the evolving regulatory environment, explain generation and utilization of different data and evidence
Drug delivery via nasal route
Over the past 10 years, the interest in intranasal drug delivery has increased. The objective of this research is to summarize recent developments on intranasal administration for local and systemic delivery, as well as for CNS indications. Nasal delivery offers many advantages over standard systemic delivery systems, nevertheless, there are still formulation limitations and side effects to be optimized. Intranasal drug delivery in the field of drug development is an interesting delivery route for the treatment of neurological disorders. Systemic approaches often fail to efficiently supply the CNS with drugs. This research describes the anatomical, histological and physiological basis and summarizes currently approved drugs for administration via intranasal delivery. Further, the research focuses on advantages and disadvantages of intranasal applied compounds and discusses formulation aspects that need to be considered for drug development.
Drift-Driven Design of Buildings : Mete Sozen’s Works on Earthquake Engineering
Summarizes the most essential concepts that every engineer designing a new building or evaluating an existing structure should consider in order to control the damage caused by drift (deformation) induced by earthquakes. It presents the work on earthquake engineering done by Dr. Mete Sozen and dozens of his collaborators and students over decades of experimentation, analysis, and reconnaissance. Many of the concepts produced through this work are integral part of earthquake engineering today. Nevertheless, the connection between the concepts in use today and the original sources is not always explained.
Diverse Roles of Integrin Receptors in Articular Cartilage
Recent studies from the authors' laboratory and from other leading groups have shown that ß1-integrins are essential for cell signalling and communication in chondrocytes. Furthermore, ß1-integrins function as mechanoreceptors in the chondrocyte mechanotransduction pathway. Their expression is therefore essential for maintaining the chondrocyte phenotype, preventing chondrocyte apoptosis and regulating chondrocyte-specific gene expression. This book volume summarizes the work that the authors have done on ß1-integrins over the last 18 years and focuses on the expression and regulation of these proteins in chondrocytes and their role in the context of the unique function of chondrocytes within articular cartilage.
Discovering Biomolecular Mechanisms with Computational Biology
In this anthology, leading researchers present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation. Discovering Biomolecular Mechanisms with Computational Biology is essential reading for life science researchers and higher-level students that work on biomolecular mechanisms and wish to understand the impact of computational biology for their success.
Diagnosis of endometrial biopsies and curettings : A practical approach
Diagnosis of Endometrial Biopsies and Curettings, 2nd edition, revised and now with color illustrations, continues the tradition of its predecessor as being the concise and complete diagnostic guide to the endometrial biopsy. The text is structured to present a logical approach to formulating a pathologic diagnosis from the diverse array of tissue received in the surgical pathology laboratory with an emphasis on differential diagnosis. More than 220 illustrations complement the text, with 70 of them in full color throughout. Each chapter includes a section on "Clinical Queries and Reporting", which summarizes the features that must be discussed in the final pathology report. The authors are two prominent gynecologic pathologists, and this book is derived from their long-running Short Course presented at the International Academy of Pathology.
Developments in Telecommunications : With a Focus on SS7 Network Reliability
This book summarizes important developments in telecommunications, including SS7 over IP, with a focus on SS7 network reliability.
Developing Students Statistical Reasoning : Connecting Research and Teaching Practice
This book is written for mathematics and statistics educators and researchers. It summarizes the research and highlights the important concepts for teachers to emphasize, and shows the interrelationships among concepts. It makes specific suggestions regarding how to build classroom activities, integrate technological tools, and assess students’ learning.
Deoxynucleoside Analogs in Cancer Therapy
Emerging as an important new volume in the renowned Cancer Drug Discovery and Development™ series, Deoxynucleoside Analogs in Cancer Therapy expertly summarizes the current status of development and application of deoxynucleoside analogs. Authoritative up-to-date reviews are presented by scientists well known in their specific areas and all contributions include valuable sound advice on structure and topics. Organized into several sections, the first part covers general aspects of drug uptake and metabolism and explains how novel technology has enabled a rapid expansion of this field. The second part is concerned with a number of specific drugs including cytarabine, gemcitabine, troxacitabine, clofarabine and Ara-G. The final section covers pharmacokinetics, prodrugs, and specific applications such as radiosensitization, gene therapy, and the use of deoxynucleoside analogs as tracers
