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Gene delivery systems development and applications
Covers the development of gene therapy today, the technology involved, clinical applications of siRNA, non-viral vector-based mRNA delivery using nanotechnology, and RNA based vaccines for treating the infectious diseases. It also presents the current application of the CRISPR/Cas9 gene-editing technique which has revolutionized genome editing and which was awarded the 2020 Nobel Prize in Chemistry. Several new drug delivery systems are explored for the applications of gene therapy. These are found to be useful in treating chronic illnesses, including cancer and infectious diseases.
Gene delivery systems : nano delivery technologies
Gene therapy involves altering the genes in the body's cells in an effort to treat or stop disease, instead of using drugs or surgery. This book discusses the development of gene therapy today, from the technology involved to gene correction and the advances in genome editing.
Gastrointestinal malignancies
Details the advances in drug discovery and delivery and the present need for emerging technologies. Throughout the text new micro and nanofabrication techniques are described, including methods such as electrohydrodynamic processes, additive manufacturing, and microfluidics, which have the potential to produce drug delivery systems that were not possible a few years ago. This book is of great use to both entry-level and experienced researchers in the field of emerging technologies for the manufacturing of drug delivery devices.
Fundamentals of Solid State Engineering
Fundamentals of Solid State Engineering, 2nd Edition, provides a multi-disciplinary introduction to Solid State Engineering, combining concepts from physics, chemistry, electrical engineering, materials science and mechanical engineering. Basic physics concepts are introduced, followed by a thorough treatment of the technology for solid state engineering. Topics include compound semiconductor bulk and epitaxial thin films growth techniques, current semiconductor device processing and nano-fabrication technologies. Examples of semiconductor devices and a description of their theory of operation are then discussed, including transistors, semiconductor lasers and photodetectors.
Fundamentals of Multibody Dynamics : Theory and Applications
This textbook—a result of the author’s many years of research and teaching—brings together diverse concepts of dynamics, combining the efforts of many researchers in the field of mechanics. Bridging the gap between dynamics and engineering applications such as microrobotics, virtual reality simulation of interactive mechanical systems, nanomechanics, flexible biosystems, crash simulation, and biomechanics, the book puts into perspective the importance of modeling in the dynamic simulation and solution of problems in these fields.
Fundamentals of Magnetism
In the last decade a tremendous progress has taken place in understanding the basis of magnetism, especially in reduced dimensions. In the first part, the fundamentals of magnetism are conveyed for atoms and bulk-like solid-state systems providing a basis for the understanding of new phenomena which exclusively occur in low-dimensional systems as the giant magneto resistance. This wide field is discussed in the second part and illustrated by copious examples. This textbook is particularly suitable for graduate students in physical and materials sciences. It includes numerous examples, exercises, and references.
Fundamentals of Friction and Wear on the Nanoscale
In the past twenty years, powerful tools such as atomic force microscopy have made it possible to accurately investigate the phenomena of friction and wear, down to the nanometer scale. Readers of this book will become familiar with the concepts and techniques of nanotribology, explained by an international team of scientists and engineers, actively involved and with long experience in this field. Edited by two pioneers in the field, 'Fundamentals of Frictions and Wear at the Nanoscale' is suitable both as first introduction to this fascinating subject, and also as a reference for researchers wishing to improve their knowledge of nanotribology and to keep up with the latest results in this field.
Fundamentals of nanoscale film analysis
The book describes the fundamentals of materials characterization from the standpoint of the incident photons or particles which interrogate nanoscale structures. These induced reactions lead to the emission of a variety of detected of particles and photons. It is the energy and intensity of the detected beams that is the basis of the characterization of the materials. The array of experimental techniques used in nanoscale materials analysis covers a wide range of incident particle and detected beam interactions.
Functionalized Nanoscale Materials, Devices and Systems
The primary objective of the NATO Advanced Study Institute (ASI) titled “Functionalized Nanoscale Materials, Devices, and Systems for Chem. -Bio Sensors, Photonics, and Energy Generation and Storage” was to present a contemporary and comprehensive overview of the field of nanostructured materials and devices and its applications in chem. -bio sensors, nanophotonics, and energy generation and storage devices. The study has become one of the most promising disciplines in science and technology, as it aims at the fundamental understanding of new physical, che- cal, and biological properties of systems and the technological advances arising from their exploration. Such systems are intermediate in size, between the isolated atoms and molecules and bulk material, where the unique transitional characteristics between the two can be understood, controlled, and manipulated.
Functional Properties of Nanostructured Materials
Nanostructured materials are becoming of major significance, and their investigations require a comprehensive approach. The fundamental properties of these materials are remarkably altered as the size of their constituent grains or phases decreases to the nanometer scale. These novel materials made of nanosized building blocks offer unique and entirely different electrical, optical, mechanical, and magnetic properties compared to conventional micro- or millimetre-size materials owing to their distinctive size, shape, topology, surface properties, etc.
Functional Molecular Nanostructures
in This book some recent advances in the structural design of nanoscale assemblies are shown, along with examples from the following areas: supramolecular catalysis, photoactive assemblies, molecular recognition and switches, and electroactive assemblies.The last decade has witnessed an unprecedented pursuit of discrete, nanoscale supramolecular aggregates, built by modern methods of self-assembly strategies. Several efficient new synthetic methods have been developed for engineering spectacular multicomponentsupramolecular aggregates.
Functional Biomaterials : Drug Delivery and Biomedical Applications
Explores in depth a wide range of functional biomaterials-based systems for drug, gene delivery, and biomedical aspects. The chapters cover newer technologies such as polymeric micelle, pH-responsive biomaterials, stimuli-responsive hydrogels, silk fibroin, inorganic biomaterials, synthetic biomaterials, 3D printed biomaterials, metallic biomaterials, ceramic and hybrid biomaterials. It also describes the theranostic approaches for cancer therapy, the biomaterials-based nanofibers scaffolds in tissue engineering, as well as the strategies applications of metallic biomaterials for the medical and dental prosthetic field.
Fullerene and Alzheimer disease
Patients have suffered for a long time from Alzheimer's disease. The presence of some obstacles in treatment, which prompted us to talk in this research on one of the modern treatments for this disease, which is fullerene. The focus was in some detail on its structure and characteristics, in addition to its applications. We especially mention its application in the treatment of Alzheimer's. This was a new step in the world of medicine and pharmacy.
Full-Chip Nanometer Routing Techniques
From a manufacturability standpoint, nanometer routers must explicitly deal with the ever increasing design complexity, and be capable of adapting to the constraint requirements of timing, signal integrity, process antenna effect, and new interconnect architecture such as X-architecture. In the nanometer era, we must look into new-generation routing technologies that combine high performance and capacity with the integration of congestion, timing, SI prevention, and DFM algorithms as the best means of getting to design closure quickly. In this book, we present a novel multilevel full-chip router, namely mSIGMA for SIGnal-integrity and MAnufacturability optimization. And these routing technologies will ensure faster time-to-market and time-to-profitability
Fuel Cells II
The concept to utilize an ion-conducting polymer membrane as a solid po- mer electrolyte offers several advantages regarding the design and operation of an electrochemical cell, as outlined in Volume 215, Chapter 1 (L. Gubler, G.G. Scherer). Essentially, the solvent and/or transport medium, e.g., H O, 2 + for the mobile ionic species, e.g., H for a cation exchange membrane, is taken up by and con?ned into the nano-dimensional morphology of the i- containingdomainsofthepolymer.Asaconsequence, aphaseseparationinto a hydrophilic ion-containing solvent phase and a hydrophobic polymer ba- bone phase establishes. Because of the narrow solid electrolyte gap in these cells, low ohmic losses reducing the overall cell voltage can be achieved, even at highcurrent densities.
Fuel Cells I
The concept to utilize an ion-conducting polymer membrane as a solid po- mer electrolyte offers several advantages regarding the design and operation of an electrochemical cell, as outlined in Volume 215, Chapter 1 (L. Gubler, G.G. Scherer). Essentially, the solvent and/or transport medium, e.g., H O, 2 + for the mobile ionic species, e.g., H for a cation exchange membrane, is taken up by and con?ned into the nano-dimensional morphology of the i- containingdomainsofthepolymer.Asaconsequence, aphaseseparationinto a hydrophilic ion-containing solvent phase and a hydrophobic polymer ba- bone phase establishes. Because of the narrow solid electrolyte gap in these cells, low ohmic losses reducing the overall cell voltage can be achieved, even at highcurrent densities.
Frontiers of Optical Spectroscopy ; Investigating Extreme Physical Conditions with Advanced Optical Techniques
Advanced spectroscopic techniques allow the probing of very small systems and very fast phenomena, conditions that can be considered "extreme" at the present status of our experimentation and knowledge. Quantum dots, nanocrystals and single molecules are examples of the former and events on the femtosecond scale examples of the latter. The purpose of this book is to examine the realm of phenomena of such extreme type and the techniques that permit their investigations. Each author has developed a coherent section of the program starting at a somewhat fundamental level and ultimately reaching the frontier of knowledge in the field in a systematic and didactic fashion. The formal lectures are complemented by additional seminars.
Frontiers of multifunctional integrated nanosystems ; Proceedings of the NATO ARW on Frontiers of molecular-scale science and technology of nanocarbon, nanosilicon and biopolymer integrated nanosystems,Ilmenau, Germany from 12 to 16 July 2003
Presents exciting new developments of the early 21st century. Significant progress has been made in nanotechnology of building blocks for integrated nanosystems, single and assembled molecules, nanoparticles characterisation, and multifunctional applications of nanosystems. The realisation and the application of novel multifunctional nanosystems in electronics, optics, biomedicine (nano-bioelectronic devices based on DNA and proteins, silicon nanocrystal memory devices, monolithically integrated silicon photonics, nanocapsules, biosensor nanosystems) are described by well known experts. This multi-disciplinary, scientific display of cutting-edge research across the entire spectrum of nanoscience and nanotechnology of inorganic, and organic systems, as well as systems for electronics photonics, and spintronics demonstrates that researching nanocarbon, nanosilicon, biomolecular integrated nanosystems, and developing their new applications, is a complex and exiting topic that will continue to attract scientists and engineers for many years to come.
Frontiers of Ferroelectricity : A Special Issue of the Journal of Materials Science
The book presents theory, fundamentals and applications of ferroelectricity. It describes the current levels of understanding of various aspects of the subject as presented by authorities in the field. Reviews and research reports cover the spectrum of ferroelectricity. Topics include relaxors, piezoelectrics, microscale and nanoscale studies, polymers and composites, unusual properties, and techniques and devices. The information in this book is intended for physicists, engineers and materials scientists working with ferroelectric materials including ceramics, single crystals, polymers, composites and even some biological materials.
Frontiers in Surface Nanophotonics : Principles and Applications
This book explores the role of surface effects in optical phenomena in nanoscience, from two different perspectives. At the level of systems of nanostructures, it translates into larger density on interfaces, which in turn leads to such intriguing collective effects as plasmonics or multiple reflection and refraction phenomena.
