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Urological Emergencies in Clinical Practice

A user-friendly pocketbook, this is easy to refer to in an emergency situation. Each chapter is clearly marked, separated and organized into sections with heading of Signs, Symptoms, Diagnosis and Management placed in a numbered fashion similar to an objective structured clinical examination. Some sections also have useful hints and tips. Covering the basics of treatment rather than going into depth, these small but very important aspects of care are usually not mentioned in "big" reference textbooks, yet form an important aspect in everyday life.

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Urological Cancers in Clinical Practice

Urological oncology constitutes 20% of all malignant disease, and includes renal, bladder, prostate and testicular cancer. This is an area of medical and scientific interest, where advances in clinical practice and translational research have led to significant changes in the way that patients are managed. The book summarizes developments in all areas of urological cancer. The aim of the book is to educate urologists and oncologists so that they are able to understand scientific developments within urological oncology and be up to date with clinical practice in this area. The book provides a guide for clinical practice.

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Urologic Robotic Surgery

Laparoscopy has allowed surgeons to perform major surgical procedures through small incisions. The introduction of laparoscopy has revolutionized the field of minimally invasive surgery. Urologic Robotic Surgery presents accepted robotic applications to treat common urological problems. Accomplished authors demonstrate their expertise in basic instrumentation and techniques, potential applications and contraindications, with attention to patient positioning and trocar placement. Despite the increasing popularity of this technology, there remains a dearth of literature available to surgeons and patients. Urologic Robotic Surgery reveals the critical steps for each procedure, reviews robotic suturing, complications, training and credentialing.

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Urinary Stone Disease : The Practical Guide to Medical and Surgical Management

Urinary stone disease has afflicted mankind for centuries and continues to be a significant medical ailment throughout the world. Contemporary management reflects the changes and evolution that have occurred in both medicine and, specifically, urology. Traditional open surgery has been nearly replaced by minimally invasive techniques, the result of technologic innovations, miniaturization of instruments, and interdisciplinary collaboration. Nevertheless, nephrolithiasis remains a chronic disease and our fundamental understanding of the pathogenesis, and molecular and genetic basis of stones as well as their prevention, remains rudimentary. In addition, interest in disease prevention continues to grow and understanding basic questions and the underlying pathophysiology of stone disease will help optimize management strategies. Future advances in urinary stone disease will be the result of collaboration among urologists, nephrologists, radiologists, dieticians, scientists, and partners in industry. Physicians must not be complacent with the current status quo or be overly eager to intervene because techniques are less invasive; rather, the goals should be a better understanding of the underlying disease process in order to identify those at risk, prophylax against stone development and recurrence, and improved nonsurgical therapies.

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Urethral Reconstructive Surgery

Urethral reconstructive surgery can often be complex, time consuming and demanding. Enlightening urologists in a practical manner, Urethral Reconstructive Surgery evaluates and manages complex urethral problems. Written by a panel of experts in the field, Urethral Reconstructive Surgery offers the anatomy of the urethra and the aspects of wound healing and applicable plastic surgical techniques. A practical and comprehensive review, Dr. Brandes and his contributors focus on the methods for evaluating the extent and degree of urethral stricture and the decision making process.

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Tumor Prevention and Genetics III

Identification of cancer risk factors and potential prevention strategies have been some of the most important medical and research contributions to the improvement of public health in the past half-century (Steele 2003). Understanding the role of lifestyle, exposure to endogenous factors and exogenous environmental factors, and individual genetic and epigenetic variability have contributed significantly to this effort. Cancer prevention strategies have been developed based on results of epidemiologic, preclinical, and clinical studies that have generated clues for identifying risk factors that may be modulated by changes in lifestyle, such as smoking cessation or dietary modification (Greenwald 2002a). In addition, significant progress in medical interventions involving chemoprevention—a pharmacological approach to intervention that aims to prevent, arrest, or reverse either the initiation phase of carcinogenesis or the progression of premalignant cells—is beginning to pay dividends in reducing risks associated with cancer.

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Tips and Tricks in Laparoscopic Urology

Each topic is limited to a few pages to produce a small and easy-to-read book.The book is extensively illustrated with line diagrams which are self-explanatory and greatly enhance the understanding of various techniques, such as position of laparoscopic ports or technique of throwing a laparoscopic stitch. Essential for urology residents, fellows, and practicing urologists, the book provides information that will be extremely useful in the performance of routine and advanced laparoscopic surgery, as well as when particular situations or difficult moments are encountered during surgery.

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The Illusion of Certainty : Health Benefits and Risks

Peels away the "veneer of certainty" which many of us attach to health risk and benefit information given to us in our daily lives. It was written and designed primarily to assist the public in comprehending and interpreting the uncertainty associated with the overwhelming amount of information on medical and environmental health risks. The book uses unique, visual presentations and case studies to explain the benefits of medical screening tests (e.g., mammography, prostate and colorectal cancer screening, cholesterol screening) and drugs (e.g., statins, Vioxx™) and the risks associated with exposure to environmental contaminants (e.g., lead, dioxin, radon). This book will help patients and their families get more involved in making medical decisions.

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Targeting the DNA damage response for cancer therapy

Discusses the latest developments in Poly (ADP-ribose) polymerase (PARP) inhibitor drug development. It focuses on the translational and clinical development of the latest drugs, as well as the evidence for regulatory approval of PARP inhibitors in multiple different molecular subtypes and tumor indications. The most-up-to-date information on basic scientific research on DNA repair pathways and the DNA Damage Response (DDR) is also covered. Every chapter contains insight into the preclinical, translational along with clinical aspects of a specific DDR inhibitor with key and expert opinion points reinforcing the most important concepts detailed to enable the reader to develop a deep understanding of the topic.

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Sunlight, Vitamin D and Skin Cancer

Represents the most important risk factor for the development of nonmelanoma skin cancer. Additionally, assessment of sun exposure parameters has consistently shown an association between the development of malignant melanoma and short term, intense UV exposure, particularly burning in childhood. As a consequence, protection of the skin from UV exposure is an integral part of skin cancer prevention programs. However, more chronic, less intense UV exposure has not been found to be a risk factor for melanoma and in fact has been found in some studies to be protective. Moreover, 90% of all requisite vitamin D is formed within the skin through the action of the sun—a serious problem—for a connection between vitamin D deficiency and various types of cancer (e. g. , colon, prostate and breast cancers) has been demonstrated in a large number of studies. Hence, the - sociation between vitamin D deficiency and various internal malignancies has now opened a debate among dermatologists and other clinicians how to balance between positive and negative effects of solar and artificial UV exposure. The goal of this volume is to provide a comprehensive, highly readable overview of our present knowledge of positive and negative effects of UV exposure, with a focus on vitamin D and skin cancer.

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Shh and Gli Signalling in Development

In this book, the chapters span vertebrate organisms from zebrafish to humans and cover development of the multiple organ systems in which the Shh signalling pathway is crucial for normal development. There are chap­ ters on the development of the central nervous system, skeletal struc­ tures, visceral organs, prostate, lung, immune system and the structures of the human face.

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Robotic Urology

Robotic surgery is in phase of worldwide rapid evolution. Data from many centers indicate that urologists are achieving equivalent or better operative outcomes using a robotic laparoscopic interface compared with their open results. Patients benefit from quicker convalescence, less pain and shorter hospital stays. The multiauthored international text covers the robotic operative procedures in Urology that are routinely performed today and still in evolution. It focuses on robotic radical prostatectomy and includes robotic procedures for the kidney, adrenal gland and urinary bladder. The most essential steps are depicted in illustrations. This book should contribute to support new robotic teams a continue to spread robotic urology.

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Robotic Urologic Surgery

The book provides instructions on how to develop a successful robotics program, learn the various techniques, and improve outcomes. The chapters are written by leading robotic urologic surgeons around the world. The body of data available is reviewed using comparisons in table format and supported by schematic diagrams and anatomic photographs to illustrate the concept being discussed.

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Radiation Oncology Advances

Radiation Oncology Advances provides a comprehensive overview of the exciting developments shaping the current and future practice of radiation oncology. Advances in treatment planning and delivery, in biological targeted therapies combined with radiation, and in functional and molecular imaging are all covered. The contributors are leaders in the field offering a critical evaluation of their clinical practice and its relevance.

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Questions in Daily Urologic Practice : Updates for Urologists and Diagnostic Pathologists

The principal role of the diagnostic surgical pathologist is to serve a patient by assisting the clinician in charge of the patient's care. In that capacity,the pathologist provides the vital informationthat should be directly and indirectly useful in guiding the clinician toward the most appropriate therapy. The material pathologists receive most commonly is a biopsy or a part of an organ removed after a definitive pro- dure. To extract useful information, pathological evaluation proceeds according to a set of guidelines. Simply reporting a diagnosis of cancer is inadequate. Detailed additional information is needed so that the clinician can go on to establish a the- peutic plan as needed. To best serve the patient, close interaction between the cli- cian and the pathologist is vital. In the field of urological pathology, there are problems specific to this system. Typically, in the prostate, because of its location, there is little room for a surgeon to work to obtain adequate resection margins, unlike with many other organs.

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Prostate Cancer : Signaling Networks, Genetics, and New Treatment Strategies

Award winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. In, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies", the authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer research, such as laparoscopic radical prostatectomy, and offers a critical evaluation and discussion of opportunities for development of novel therapies for prostate cancer. Clinical trials that have not been covered or evaluated in any other books currently available are also discussed. Invaluable to physicians and researchers, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies" provides a comprehensive translational resource as well as an important source of information for prostate cancer patients.

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Prostate Cancer : Diagnosis, staging and latest studies

The prostate is a part of the male reproductive system, which includes the penis, prostate, seminal vesicles, and testicles. The prostate is located just below the bladder and in front of the rectum. It is about the size of a walnut and surrounds the urethra (the tube that empties urine from the bladder). It produces fluid that makes up a part of semen. As a man ages, the prostate tends to increase in size. This can cause the urethra to narrow and decrease urine flow. This is called benign prostatic hyperplasia, and it is not the same as prostate cancer.

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Prostate Cancer : Biology, Genetics, and the New Therapeutics

The volume profiles the latest advances in cancer research and treatment and includes profound studies in prostate stem cells, cancer-host interactions, hedgehog signaling in development and cancer, cholesterol and cell signaling, gene therapy for advanced prostate cancer, and noninvasive strategies such as molecular imaging to visualize gene expression. This new edition also investigates expression profiling and somatic alterations in prostate cancer progression and linkage studies of prostate cancer families to identify susceptibility genes. The issues of racial differences in prostate cancer mortality, radiotherapy for the treatment of locally advanced prostate cancer, recombinant antibody candidates for treatment, taxane-based chemotherapy, lethal phenotypes, and novel and efficient translation clinical trials are also presented in great depth

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Prostate Cancer

Prostate cancer is still evolving fol- cancer at earlier stages and the increased use of lowing improvements in disease detection and hormone therapy in earlier disease stages many better understanding of disease characteristics. patients will receive hormone therapy for a long Tis book addresses the current state of the art in period. Tese patients are at risk of acute and this still-developing feld and presents the reader chronic side efects of hormonal therapy. Te- with the information needed to make rational fore, the timing of initiating hormone therapy, patient decisions regarding treatment selection the type of hormone therapy and the monitoring and outcomes. of patients on long-term hormone therapy have Te growing body of knowledge regarding become crucial in the appropriate management epidemiology, pathogenesis, prevention, screen- of patients with prostate cancer. ing, diagnosis and staging is included in the frst Disease management in men with prostate half of the book.

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Prostate Biopsy : Indications, Techniques, and Complications

Advances in prostate biopsy have made major complications uncommon and prostate biopsy is now one of the most common procedures performed by urologists. In Prostate Biopsy: Indications, Techniques, and Complications, all topics related to the diagnosis of prostate cancer, including risk factor assessment, indications for biopsy, techniques, complications, and emerging technologies in the science are presented. Topics of great importance in the field of prostate biopsy such as PSA, pain prevention, prediction models, and biopsy techniques are addressed Internationally acclaimed specialists provide their expert opinions on all topics related to prostate cancer diagnosis.

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