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Multichain Immune Recognition Receptor Signaling : From Spatiotemporal Organization to Human Disease
The central idea of this book is to show that the structural similarity of the MIRRs determines the general principles underlying MIRR-mediated transmembrane signaling mechanisms and also provides the basis for existing and fixture therapeutic strategies targeting MIRRs. The reviews assembled in this book detail the prog-ress in defining and controlling the spatiotemporal organization of key events in immune cell activation. An improved understanding of MIRR-mediated signaling has numerous potential practical applications, fi-om the rational design of drugs and vaccines to the engineering of cells for biotechnological purposes.
Multi-Carrier Spread Spectrum 2007 ; Proceedings from the 6th International Workshop on Multi-Carrier Spread Spectrum, May 2007,Herrsching, Germany
This combination known as multi-carrier spread spectrum (MC-SS) benefits from the advantages of both systems and offers high flexibility, high spectral efficiency, simple detection strategies, narrow-band interference rejection capabilities, etc. The basic principle of this combination is straightforward: The spreading is performed as direct sequence spread spectrum (DS-SS) but instead of transmitting the chips over a single carrier, several sub-carriers are employed. The MC modulation and demodulation can easily be realized in the digital domain by performing IFFT and FFT operations. The separation of the users’ signals can be performed in the code domain. MC-SS systems can perform the spreading in frequency direction, which allows for simple signal detection strategies. Since 1993, MC-SS has been deeply studied and new alternative solutions have been proposed.
Medical Emergency Teams : Implementation and Outcome Measurement
Why Critical Care Evolved METs? In early 2004, when Dr. Michael DeVita informed me that he was cons- ering a textbook on the new concept of Medical Emergency Teams (METs), I was surprised. At Presbyterian-University Hospital in Pittsburgh we int- duced this idea some 15 years ago, but did not think it was revolutionary enough to publish. This, even though, our fellows in critical care medicine training were all involved and informed about the importance of “C- dition C (Crisis),” as it was called to distinguish it from “Condition A (Arrest). ”We thought it absurd to intervene only after cardiac arrest had occurred,because most cases showed prior deterioration and cardiac arrest could be prevented with rapid team work to correct precluding problems. The above thoughts were logical in Pittsburgh, where the legendary Dr. Peter Safar had been working since the late 1950s on improving current resuscitation techniques, ?rst ventilation victims of apneic from drowning, treatment of smoke inhalation, and so on. This was followed by external cardiac compression upon demonstration of its ef?ciency in cases of unexpected sudden cardiac arrest. Dr. Safar devoted his entire professional life to improvement of cardiopulmonary resuscitation. He and many others emphasized the importance of getting the CPR team to o- of-hospital victims of cardiac arrest as quickly as possible.
High-Latitude Bioerosion : The Kosterfjord Experiment
Bioerosion is the major force driving the degradation of marine skeletal carbonates and limestone coasts. A wide spectrum of mechanical and/or chemical boring, scraping or crushing organisms break down calcereous substrates, comprising various grazers, macroborers and especially microborers. Their traces on and within hard substrates are known from fossil carbonates as old as the Precambrian and serve as valuable palaeoenvironmental indicators. Bioerosion processes have been extensively studied in tropical seas, while corrsponding investigations from cold-temperate to polar settings remain sparse. For the first time, an experimental study yields insight into the pace of carbonate degradation and the chronology of boring community development along a bathymetric gradient in a high-latitude setting.
Diagrammatic Representation and Inference ; 5th International Conference, Diagrams 2008, Herrsching, Germany, September 19-21, 2008. Proceedings
This book constitutes the refereed proceedings of the 5th International Conference on Theory and Application of Diagrams, Diagrams 2008, held in Herrsching, Germany, in September 2008.
Data and applications security XIX ; 19th Annual IFIP WG 11.3 working conference on data and applications security, Storrs, CT, USA, August 7-10, 2005, Proceedings
Constitutes the refereed proceedings of the 19th Annual Working Conference on Data and Applications Security held in Storrs, CT, USA, in August 2005. The papers present theory, technique, applications, and practical experience of data and application security with topics like cryptography, privacy, security planning and administration, and more.
