Page 1
Page 1
Ontology Management : Semantic Web, Semantic Web Services, and Business Applications
This volume describes relevant tasks, practical and theoretical challenges, limitations and methodologies, plus available software tools. The editors discuss integrating the conceptual and technical dimensions with a business view on using ontologies, by stressing the cost dimension of ontology engineering and by providing guidance on how up-to-date tooling helps to build, maintain, and use ontologies. Also included is a one-stop reference on all aspects of managing ontological data and best practices on ontology management for a number of application domains.
Ontology Alignment : Bridging the Semantic Gap
Ontology Alignment: Bridging the Semantic Gap introduces novel methods and approaches for semantic integration. In addition to developing new methods for ontology alignment, the author provides extensive explanations of up-to-date case studies. The topic of this book, coupled with the application-focused methodology, will appeal to professionals from a number of different domains.
Ontologies for Software Engineering and Software Technology
The editors structured the contributions into three parts: first, a detailed introduction into the use of ontologies in software engineering and software technology in general; second, the use of ontologies to conceptualize different process-related domains such as software maintenance, software measurement, or SWEBOK, initiated by IEEE; third, the use of ontologies as artifacts in several software processes, like, for example, in OMG’s MOF or MDA.
Online Storage Systems and Transportation Problems with Applications : Optimization Models and Mathematical Solutions
This books covers the analysis and development of online algorithms involving exact optimization and heuristic techniques, and their application to solve two real life problems. The first problem is concerned with a complex technical system: a special carousel based high-speed storage system - Rotastore. It is shown that this logistic problem leads to an NP-hard Batch PreSorting problem which is not easy to solve optimally in offline situations. The second problem originates in the health sector and leads to a vehicle routing problem. Reasonable solutions for the offline case covering a whole day with a few hundred orders are constructed with a heuristic approach, as well as by simulated annealing. Optimal solutions for typical online instances are computed by an efficient column enumeration approach leading to a set partitioning problem and a set of routing-scheduling subproblems. The latter are solved exactly with a branch-and-bound method which prunes nodes if they are value-dominated by previous found solutions or if they are infeasible with respect to the capacity or temporal constraints.
Online hate speech in the European Union : A discourse-analytic perspective
open access under a CC BY 4.0 license and reports on research carried out as part of the European Union co-funded C.O.N.T.A.C.T. project which targeted hate speech and hate crime across a number of EU member states. It showcases the bearing that discourse analytic research can have on our understanding of this phenomenon that is a growing global cause for concern.
One-Dimensional Nanostructures
One-dimensional (1D) nanostructures, including nanowires, nanotubes and quantum wires, have been regarded as the most promising building blocks for nanoscale electronic and optoelectronic devices. Worldwide efforts in both the theory and the experimental investigation of growth, characterization and applications of 1D nanostructures have resulted in a mature, multidisciplinary field. In this book, a wealth of state-of-the-art information offers the opportunity to uncover the underlying science from diverse perspectives. Leading researchers elucidate the synthesis and properties of 1D nanostructures for various morphologies and compositions (semiconductor, metal, carbon, etc.) as well as their considerable impact on spintronics, information storage, and the design of field-effect transistors.
Ondansetron Patches
The objective of this study was to develop the matrix of transdermal drug delivery system (TDDS) of ondansetron hydrochloride (ODH), in which ondansetron is the first serotonin subtype 3 receptor antagonist indicated for the treatment and/or prophylaxis of postoperative, chemotherapy or radiotherapy induced emesis. It has been proven efficient and safe to treat such symptoms, by using in vitro drug release study and evaluate the effect of eucalyptus oil and different percentage of carbopol 940. The result of drug release decreased by increasing the percentage of carbopol 940 which achieved the purpose of the study by prolonging the release of the ondansetron . The patch provides a means to reduce the side effects associated with its oral therapy, avoidence of the first-pass metabolism and minimize inconsistency in absorption across GIT. Various types of transdermal patches are used to incorporate the active ingredients into the circulatory system via skin.
Oncology : An Evidence-Based Approach
Reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology.
Oncologic and Cardiologic PET/CT-Diagnosis : An Interdisciplinary Atlas and Manual
Since 1999/2000 simultaneous imaging of anatomical features and metabolic activities using fused PET and CT images has complemented and in many cases even replaced what was originally done as separate analysis. – Is this a small revolution? – In fact, this new approach can be considered to be without a rival for imaging diagnosis. The complementary efforts of nuclear medicine physicians and radiologists have improved the diagnostic value of PET/CT scans. The successful use of PET/CT in the field of oncology has been documented world-wide, and in cardiology we can take advantage of the significant findings of PET diagnosis, particularly in the USA. New prospects are now available for paediatric oncology and molecular medicine.
Oncogenes Meet Metabolism : From Deregulated Genes to a Broader Understanding of Tumour Physiology
In 1920s, Otto Warburg described the phenomenon of ‘aerobic glycolysis’, the ability of tumour cells to convert glucose to lactate in the presence of normal oxygen conditions. Warburg’s hypothesis of an altered metabolism in cancer cells found no immediate acceptance, though it was latter confirmed for most human tumours. With the advent of molecular biology the focus in tumour research has shifted towards the search for oncogenes. However, the interest in cancer molecular profiling eventually led to a renaissance of the Warburg effect trying to combine genetic alterations with effects on metabolism with the help of modern analytic technologies to rapidly analyze broad varieties of metabolites in various tissues and bodyfluids (metabonomics).
On the Topology of Isolated Singularities in Analytic Spaces
The aim of this book is to give an overview of selected topics on the topology of real and complex isolated singularities, with emphasis on its relations to other branches of geometry and topology. The first chapters are mostly devoted to complex singularities and a myriad of results spread in a vast literature, which are presented here in a unified way, accessible to non-specialists. Among the topics are the fibration theorems of Milnor; the relation with 3-dimensional Lie groups; exotic spheres; spin structures and 3-manifold invariants; the geometry of quadrics and Arnold's theorem which states that the complex projective plane modulo conjugation is the 4-sphere. The second part of the book studies pioneer work about real analytic singularities which arise from the topological and geometric study of holomorphic vector fields and foliations. In the low dimensional case these turn out to be related to fibred links in the 3-sphere defined by meromorphic functions. This provides new methods for constructing manifolds equipped with a rich geometry.
On the move to meaningful internet systems 2007 : OTM 2007 Workshops ; OTM Confederated International Workshops and Posters, AWeSOMe, CAMS, OTM Academy Doctoral Consortium, MONET, OnToContent, ORM, PerSys, PPN, RDDS, SSWS, and SWWS 2007, Vilamoura, Portugal, November 25-30, 2007,
it is clear that there is an acute and increasing need to address and discuss in an integrated forum the implied software and system issues as well as methodological, semantical, theoretical and application issues. As we all know, e-mail, the Internet, and even video conferences are not sufficient for effective and efficient scientific exchange. This is why the OnTheMove (OTM) Federated Conferences series has been created to cover the increasingly wide yet closely connected range of fundamental technologies such as data and Web Semantics.
On the construction of engineering handbooks : With an Illustration from the railway safety domain
This book is the first to reflect upon the question of how to construct a desktop handbook. It is demonstrated how concept analysis can be used for identifying settled knowledge as the key ingredient by utilizing the assembled data for classification; a presentation scheme for handbook articles is developed and demonstrated to be suitable. The sketched approach is then illustrated by an example from the railway safety domain. Finally, the limitations of the presented methods are discussed.
Omics sudies of medicinal plants
Herbal drugs play a pivotal role in modern medicine and pharmaceutical care; however, only limited biotechnology applications have been seen in medicinal plants. Revolutions in high-throughput approaches emphasize omics approaches, such as genomics, transcriptomics, proteomics, and metabolomics. A volume in the Exploring Medicinal Plants series, this book provides a comprehensive and in-depth analysis of breakthroughs in high-throughput approaches for the research of medicinal plants.
Old and New Perspectives on Mortality Forecasting
This book describes methods of mortality forecasting and discusses possible improvements. It contains a selection of previously unpublished and published papers, which together provide a state-of-the-art overview of statistical approaches as well as behavioural and biological perspectives. The different parts of the book provide discussions of current practice, probabilistic forecasting, the linearity in the increase of life expectancy, causes of death, and the role of cohort factors.
Oil Spill Response : A Global Perspective
This book provides a timely international perspective on applied research and development, technology transfer, and “lessons learned” from field trials and actual case studies associated with recent spill events. This book provides a synopsis as to the methods currently employed to deals with spills and an insight on future technologies under development.
Offshore Risk Assessment : Principles, Modelling and Applications of QRA Studies
This updated and expanded second edition has been informed by a major R&D programme on offshore risk assessment in Norway (2002–2006), and reflects the trend of expanded use of floating production installations. It starts with a thorough discussion of risk metrics and risk analysis methodology with subsequent chapters devoted to analytical approaches to escalation, escape, evacuation and rescue analysis of safety and emergency systems. Separate chapters analyse the main hazards of offshore structures: fire, explosion, collision and falling objects. Risk mitigation and control are discussed, as well as an illustration of how the results from quantitative risk assessment studies should be presented. The second edition has a stronger focus on the use of risk assessment techniques in the operation of offshore installations. Also decommissioning of installations is covered.
Official Statistics 4.0 : Verified Facts for People in the 21st Century
Explores official statistics and their social function in modern societies. Digitisation and globalisation are creating completely new opportunities and risks, a context in which facts (can) play an enormously important part if they are produced with a quality that makes them credible and purpose-specific. In order for this to actually happen, official statistics must continue to actively pursue the modernisation of their working methods.
Office-Based Maxillofacial Surgical Procedures : A Step-by-step Approach
This book is a comprehensive, step-by-step guide to maxillofacial surgical procedures typically performed in an office setting. Health care providers will be able to use the book as a resource to expand their knowledge on common maxillofacial surgical procedures.
Oculoplastic Surgery Atlas : Cosmetic Facial Surgery
The previous volume in this series covered reconstructive eyelid surgery. This volume presents many aspects of facial cosmetic surgery, including blepharoplasty, endoscopic forehead surgery, rhytidectomy, and other related procedures. Future volumes will pr- ent facets of lacrimal and orbital surgery.
