الصفحة 92
الصفحة 92
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Access to medicines and vaccines : Implementing flexibilities under intellectual property law

This book is the outcome of a Global Forum on Innovation, Intellectual Property and Access to Medicines held in December 2019 at the Max Plank Instititute in Munich, organised by the South Centre and the Max Plank Institute. The academics and experts from international organisations participating have contributed chapters to this book. The book is for policy makers (in Ministries of Health, Ministries of Trade, Ministries of Foreign Affairs, patent offices), but also relevant for academics (law, trade, public health), on the flexibilities available in the Agreement on Trade Related Aspects of Intellectual Property Rights (TRIPS) of the World Trade Organization to promote access to medicines.

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Abuse of Dominant Position : New Interpretation, New Enforcement Mechanisms?

As part of its review of competition law that started in the late 1990s, the European Commission proposes to revise its interpretation and application of the Treaty’s prohibition of abuses of dominant positions. Also, it has instigated a debate about the promotion of private enforcement of EC competition law. The chapters in this volume critically appraise the Commission’s proposals, including the most recent ones. The authors also highlight the repercussions of the proposed ‘more economic approach’ to abuses of dominant positions on private litigants’ opportunities to bring damages actions in national courts for such abuses.

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Abstraction, Reformulation, and Approximation ; 7th International Symposium, SARA 2007, Whistler, Canada, July 18-21, 2007, Proceedings

This volume contains the proceedings of SARA 2007, the seventh symposium, held at Whistler Village, British Columbia, Canada, July 18-21. Three distinguished speakers were invited to give keynote presentations, and their abstracts are included herein,It has been recognized since the inception of artificial intelligence that abstractions, problem reformulations and approximations (AR&A) are central to human common-sense reasoning and problem solving and to the ability of systems to reason effectively in complex domains.AR&A techniques have been used in a variety of problem-solving settings, including automated reasoning, cognitive modelling.

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Abstraction, reformulation and approximation ; 6th International symposium, SARA 2005, Airth Castle, Scotland, UK, July 26-29, 2005, proceedings

This volume contains the proceedings of the 6th Symposium on Abstraction, Reformulation and Approximation (SARA 2005). the proceedings have been published in the LNAI series of Springer. Abstractions, reformulations and approximations (AR&A) have found app- cationsin avarietyofdisciplines andproblems, including constraintsatisfaction, design, diagnosis, machine learning, planning, qualitative reasoning, scheduling, resource allocation and theorem proving, but are also deeply rooted in philo- phy and cognitive science. The papers in this volume capture a cross-section of the various facets of the ?eld and of its applications. One of the primary uses of AR&A is oriented to overcome computational intractability. AR&A techniques, however, have also proved useful for knowledge acquisition, explanation and other applications.

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Abstract State Machines, B and Z ; 1st International Conference, ABZ 2008, London, UK, September 16-18, 2008. Proceedings

This book constitutes the refereed proceedings of the First International Conference of Abstract State Machines, B and Z, ABZ 2008, held in London, UK, in September 2008.

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Abstract Computing Machines : A Lambda Calculus Perspective

The book addresses ways and means of organizing computations, highlighting the relationship between algorithms and the basic mechanisms and runtime structures necessary to execute them using machines. It completely abstracts from concrete programming languages and machine architectures, taking instead the lambda calculus as the basic programming and program execution model to design various abstract machines for its correct implementation. The emphasis is on fully normalizing machines based on full-fledged beta-reductions as essential prerequisites for symbolic computations that treat functions and variables truly as first-class objects. Their weakly normalizing counterparts are shown to be functional abstract machines that sacrifice the flavors of full beta-reductions for decidedly simpler runtime structures and improved runtime efficiency. Further downgrading of the lambda calculus leads to classical imperative machines that permit side-effecting operations on the runtime environment.

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A vision-based system to early detection of drowning incidents in swimming pools

Being one of the leading causes of death; drowning has become a severe problem in the past few years. Our goal from this project is to focus on the comprehensive survey of drowning detection and prevention techniques. There are various methodologies put up in the domain of swimming pool safety using different intelligent control systems. Various methods have been adopted for drowning detection using the concepts of image processing, pressure and motion sensing. The main objectives of this work are to detect the drowning person in an indoor swimming pool and send an alarm to the lifeguard to rescue if the previously detected person is missing for a specific amount of time.

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A Time for Metabolism and Hormones

Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.

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A Subtle and Mysterious Machine : The Medical World of Walter Charleton (1619-1707)

Walter Charleton (1619-1707) has been widely depicted as a natural philosopher whose intellectual career mirrored the intellectual ferment of the ‘scientific revolution’. Instead of viewing him as a barometer of intellectual change, I examine the previously unexplored question of his identity as a physician. Examining three of his vernacular medical texts, this volume considers Charleton’s thoughts on anatomy, physiology and the methods by which he sought to understand the invisible processes of the body.

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A short guide to clinical pharmacokinetics

Consists of seven chapters that cover various aspects of pharmacokinetics and its clinical applications. The chapters are structured to provide clear objectives and keywords are bolded throughout the text to facilitate understanding. The topics covered include the significance of pharmacokinetics in clinical practice, factors affecting pharmacokinetic parameters, pharmacokinetic drug interactions, therapeutic drug monitoring, dosage adjustment in different population groups, the influence of hepatic diseases on pharmacokinetics and the impact of pharmacogenomics on pharmacokinetics and pharmacodynamics.

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A Sea Change: The Exclusive Economic Zone and Governance Institutions for Living Marine Resources

A Sea Change in a Changing Sea The oceans, seas and coastal areas encompass over 70% of the earth’s surface. They are a critical driver of the earth’s hydrologic cycle and climate system, important for c- merce, transport, and tourism, a source of economically important living marine resources, minerals such as hydrocarbons, as well as new pharmaceutical compounds. The marine environment provides essential habitats for thousands of marine living 1 2 resources, which in turn contribute significantly to global food security, employment, 3 and trade. Overall, the sea’s contribution to human welfare, in terms of market and non-market resources and environmental services, has been estimated at US$21 trillion/year (Costanza, 2000). However, despite the importance of the ocean realm to humans, there is a growing sense that human impacts are destabilizing this system. Some experts believe that current fishing levels are approaching or exceeding the total 4 productivity of the ocean ecosystem (National Research Council, 1999).

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A practical guide on behaviour change support for self-managing chronic disease

Developed under the auspices of the Train4Health project, funded by the Erasmus+ program of the European Union, the book contains six chapters written by international contributors from different disciplines. Chapter one introduces the competencies necessary for delivering effective behavior change support, based on an established program of work, and related learning outcomes. The four following chapters describe how these competencies can be acquired, focusing on concepts and theories, assessing self-management behaviors, implementing change strategies and person-centered communication, using a practical approach.

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A Modern Course in Aeroelasticity

In this new edition, the fundamental material on classical linear aeroelasticity has been revised. Also new material has been added describing recent results on the research frontiers dealing with nonlinear aeroelasticity as well as major advances in the modelling of unsteady aerodynamic flows using the methods of computational fluid dynamics and reduced order modeling techniques.

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A Matrix Algebra Approach to Artificial Intelligence

The book consists of two parts: the first discusses the fundamentals of matrix algebra in detail, while the second focuses on the applications of matrix algebra approaches in AI. Highlighting matrix algebra in graph-based learning and embedding, network embedding, convolutional neural networks and Pareto optimization theory, and discussing recent topics and advances, the book offers a valuable resource for scientists, engineers, and graduate students in various disciplines

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A History of Male Psychological Disorders in Britain, 1945–1980

Explores the under-researched history of male mental illness from the mid-twentieth century. It argues that statistics suggesting women have been more vulnerable to depression and anxiety are misleading since they underplay a host of alternative presentations of 'distress' more common in men.

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A Guide to Graph Algorithms

Offers high-quality content in the research area of graph algorithms and explores the latest developments in graph algorithmics. The reader will gain a comprehensive understanding of how to use algorithms to explore graphs. It is a collection of texts that have proved to be trend setters and good examples of that. The book aims at providing the reader with a deep understanding of the structural properties of graphs that are useful for the design of efficient algorithms. These algorithms have applications in finite state machine modelling, social network theory, biology, and mathematics. The book contains many exercises, some up at present-day research-level. The exercises encourage the reader to discover new techniques by putting things in a clear perspective.

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A Geometric Approach to Differential Forms

The modern subject of differential forms subsumes classical vector calculus. This text presents differential forms from a geometric perspective accessible at the undergraduate level. The book begins with basic concepts such as partial differentiation and multiple integration and gently develops the entire machinery of differential forms. Each new concept is presented with a natural picture that students can easily grasp. Algebraic properties then follow. This facilitates the development of differential forms without assuming a background in linear algebra. Throughout the text, emphasis is placed on applications in 3 dimensions, but all definitions are given so as to be easily generalized to higher dimensions. A centerpiece of the text is the generalized Stokes' theorem. Although this theorem implies all of the classical integral theorems of vector calculus, it is far easier for students to both comprehend and remember.

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A Dictionary of Biomedicine

A Dictionary of Biomedicine fills the need to define the specialist language used within an evolving field by offering clear, concise definitions of even the most complex biomedical terms. It includes more than 10,000 A-Z entries on all areas of biomedicine, such as genomics and biomedical science. Entries are authoritative and wide-ranging, covering terms from the related areas of anatomy, genetics, molecular bioscience, pathology, pharmacology, and clinical medicine.

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A Concise Introduction to Languages and Machines

This easy-to-follow text provides an accessible introduction to the key topics of formal languages and abstract machines within Computer Science.

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A Computer Scientists Guide to Cell Biology

Provides a succinct treatment of the general concepts of cell biology, furnishing the computer scientist with the tools necessary to read and understand current literature in the field.After a brief introduction to cell biology, the text focuses on the principles behind the most-widely used experimental procedures and mechanisms, relating them to well-understood concepts in computer science. The presentation of the material has been prepared for the reader’s quick grasp of the topic: comments on nomenclature and background notes can be ascertained at a glance, and essential vocabulary is boldfaced throughout the text for easy identification.

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