Molecular autoimmunity
The autoimmune disease paroxysmal cold hemoglobinuria, a rare hemolytic disorder. After a century of research, the list of autoimmune diseases has become impressive. With a prevalence of approximately 5% of the world-wide population, these chronic, debilitating conditions affect almost every major organ of the body and, for reasons that remain unclear, are much more prevalent in woman than in men. Despite our rapidly expanding knowledge of the cellular and molecular pathways that govern a normal immune response, deciphering the precise etiology of autoimmune diseases remains an important challenge. Over the last few years, our understanding of the pathogenesis of autoimmune diseases has improved rapidly, leading to the emergence of elegant immunointervention strategies. Molecular Autoimmunity illustrates how cutting-edge research is continuing to advance our understanding of autoimmune disease mechanisms and identifies novel therapeutic targets that provide a hope for effective future treatments. This volume contains a selected number of exciting advances in unraveling autoimmune reactions, and the resulting new armory of experimental immunotherapies that may lead to new ways of controlling autoimmune reactions.
Modern implant dentistry
A comprehensive look at the state of implant dentistry today, equipping beginners and seasoned clinicians alike to improve their skills and practice implant dentistry safely and predictably. The early chapters focus on the biology of dental implants as well as medical considerations required prior to placing them, followed by chapters dedicated to documentation, treatment planning, and digital workflow. Surgical concepts are then described in detail, from single-tooth extraction to guided All-on-X treatment, followed by detailed discussion of the prosthetic options available in implant dentistry. The final chapters include relevant topics such as soft tissue management in implant dentistry, treatment of peri-implant disease, the socket shield technique, and marketing of dental implant therapy. Written by experienced clinicians from all over the world, the book includes over 60 surgical and clinical videos (linked via QR codes) to demonstrate what the procedures and techniques and products look like in real life, not in a photograph taken in ideal conditions, so readers can be confident in their understanding.
Modern Econometric Analysis : Surveys on Recent Developments
The importance of empirical economics and econometric methods has greatly in creased during the last 20 years due to the availability of better data and the improved performance of computers. In an information-driven society such as ours we need quickly to obtain complete and convincing statistical results. This is only possible if the appropriate econometric methods are applied. Traditional econometric analysis concentrates on classical methods which are far from suitable for handling actual economic problems.
Modern Deep Learning Design and Application Development : Versatile Tools to Solve Deep Learning Problems
Learn how to harness modern deep-learning methods in many contexts. Packed with intuitive theory, practical implementation methods, and deep-learning case studies, this book reveals how to acquire the tools you need to design and implement like a deep-learning architect. It covers tools deep learning engineers can use in a wide range of fields, from biology to computer vision to business. With nine in-depth case studies, this book will ground you in creative, real-world deep learning thinking. You will: Improve the performance of deep learning models by using pre-trained models, extracting rich features, and automating optimization. Compress deep learning models while maintaining performance. Reframe a wide variety of difficult problems and design effective deep learning solutions to solve them. Use the Keras framework, with some help from libraries like HyperOpt, TensorFlow, and PyTorch, to implement a wide variety of deep learning approaches.
Modern Aspects of Electrochemistry ; Vol. 42
MODERN ASPECTS OF ELECTROCHEMISTRY No. 42 Edited by Constantinos Vayenas University of Patras, Greece Topics in Number 42 include: The electrochemistry and electrocatalysis of Ruthenium in regards to the development of electrodes for Polymer Electrolyte Membrane (PEM) fuel cells Breakthroughs in Solid Oxide Fuel Cell (SOFC) anodes and cathodes leading to improved electrocatalysis Electrocatalysis of the electrochemical reduction of CO2 on numerous metals The interfacial phenomena of electrodeposition and codeposition, and the need for new theoretical analyses of the electrode-electrolyte interface Advantages of scanning tunneling microscopy (STM) in understanding the basics of catalysis, electrocatalysis and electrodeposition The role of electrochemistry in emerging technologies including electrodeposition and electroforming at the micro and nano levels, semiconductor and information storage, including magnetic storage devices.
Modern Aspects of Electrochemistry ; Vol. 38
Solid State Electrochemistry encompassing modern equilibria concepts, thermodymanics and kinetics of charge carriers in solids.,Electron transfer processes, with special sections devoted to hydration of the proton and its heterogeneous transfer.Electrosorption at electrodes and its relevance to electrocatalysis and electrodeposition of metals,The behavior of Pt and other alloy electrocatalyst crystallites used as the electrode materials for phosphoric acid electrolyte fuel-cells.Applications of reflexology and electron microscopy to the materials science aspect of metal electrodes.Electroplating of metal matrix composites by codeposition of suspended particles, a process that has improved physical and electrochemical properties.
Models, Methods and Tools for Product Service Design : The Manutelligence Project
This book summarizes research being pursued within the Manutelligence project, the goal of which is to help enterprises develop smart, social and flexible products with high value added services. Manutelligence has improved Product and Service Design by developing suitable models and methods, and connecting them through a modular, collaborative and secure ICT Platform. The use of real data collected in real time by Internet of Things (IoT) technologies underpins the design of product-service systems and makes it possible to monitor them throughout their life cycle. Available data allows costs and sustainability issues to be more accurately measured and simulated in the form of Life Cycle Cost (LCC) and Life Cycle Assessment (LCA). Analysing data from IoT systems and sharing LCC and LCA information via the ICT Platform can help to accelerate the design of product-service systems, reduce costs and better understand customer needs. Industrial partners involved in Manutelligence provide a clear overview of the project's outcomes, and demonstrate how its technological solutions can be used to improve the design of product-service systems and the management of product-service life cycles.
Models for computer aided tolerancing in design and manufacturing ; Selected conference papers from the 9th CIRP International Seminar on Computer-aided tolerancing, held at Arizona State University, Tempe, Arizona, USA, 10-12 April, 2005
Computer Aided Tolerancing (CAT) is an important topic in any field of design and production where parts move relative to one another and/or are assembled together. Geometric variations from specified dimensions and form always occur when parts are manufactured. Improvements in production systems can cause the amounts of the variations to become smaller, but their presence does not disappear. To shorten the time from concept to market of a product, it has been increasingly important to take clearances and the tolerancing of manufacturing variations into consideration right from the beginning, at the stage of design. Hence, geometric models are defined that represent both the complete array of geometric variations possible during manufacture and also the influence of geometry on the function of individual parts and on assemblies of them.
Modeling and simulation tools for emerging telecommunication networks : Needs, trends, challenges and solutions
This book contains a selection of papers presented at a symposium organized under the aegis of COST Telecommunications Action 285. The main objective of the Action is to enhance existing tools and develop new modeling and simulation tools for research in emerging multi-service telecommunication networks in the areas of model performance improvements, multilayer traffic modeling, and the important issue of evaluation and validation of the new modeling tools.
Model and Design of Improved Current Mode Logic Gates : Differential and Single-ended
This book presents MOSFET-based current mode logic (CML) topologies, which increase the speed, and lower the transistor count, supply voltage and power consumption. The improved topologies modify the conventional PDN, load, and the current source sections of the basic CML gates.
Mobile Robots : The Evolutionary Approach
The design and control of autonomous intelligent mobile robotic systems operating in unstructured changing environments includes many objective difficulties. There are several studies about the ways in which, robots exhibiting some degree of autonomy, adapt themselves to fit in their environments. The application and use of bio-inspired and intelligent techniques such as reinforcement learning, artificial neural networks, evolutionary computation and so forth in the design and improvement of robot designs is an emergent research topic. Researchers have obtained robots that display an amazing slew of behaviours and perform a multitude of tasks. These include perception of environment, planning and navigation in rough terrain, pushing boxes, negotiating an obstacle course, etc.
Mobile Professional Voluntarism and International Development : Killing Me Softly?
This book explores the impact that professional volunteers have on the low resource countries they choose to spend time in. Whilst individual volunteering may be of immediate benefit to individual patients, this intervention may have detrimental effects on local health systems; distorting labour markets, accentuating dependencies and creating opportunities for corruption. Improved volunteer deployment may avoid these risks and present opportunities for sustainable systems change. The empirical research presented in this book stems from a specific volunteering intervention funded by the Tropical Health Education Trust and focused on improving maternal and newborn health in Uganda.
Mobile health technologies for ambient assisted living and healthcare
The use of telemedicine and mobile devices is growing, and sensors might aid in creating creative solutions. Developing these solutions is crucial for monitoring senior citizens, lifestyles, and medical procedures. The development of assistive technology for various users to follow sports and other activities is strongly tied to this study area. Data protection is crucial, and the development of these solutions for medical uses should be verified. The security and privacy of the information may be tied to other recognized research projects for their acceptability. ICT research has considerably improved quality of life and has fully assimilated all citizens into society through medical rehabilitation and assistive technology. The technologies and research fields that influence medical informatics include databases, networking, graphical user interfaces, data mining, machine learning, intelligent decision support systems, and specialized programming languages.
Minimal English for a Global World : Improved Communication Using Fewer Words
This book introduces a new tool for improving communication and promoting clearer thinking in a world where the use of Global English can create numerous comprehension and communication issues. Based on research findings from cross-linguistic semantics, it contains essays and studies by leading experts exploring the value and application of ‘Minimal English’ in various fields, including ethics, health, human rights discourse, education and international relations.
Mild Stress and Healthy Aging : Applying hormesis in aging research and interventions
Stress is a double edged sword. Whereas chronic stress has well known harmful effects, recent research shows that intermittent exposure of cells and organisms to mild stress can improve various biological parameters, including severe stress tolerance, health span and longevity. Mild stress-induced hormesis is potentially a powerful tool in gerontological research and interventions. This book brings together some of the world leaders in this area of research who present a critical analysis of the ongoing research with respect to the effects and mechanisms of action of various types of mild stress, such as irradiation, heat, physical exercise, hypergravity, pro-oxidants and nutritional components, on a variety of biological systems ranging from fruitflies to human cells and bodies. Their separate chapters and a final collective chapter open up a whole new world of possibilities for future research in aging, successful aging, and health span extension.
Microsoft Visual C# Step by Step
Guide to Microsoft Visual C# fundamentals with Visual Studio. Expand your expertiseand teach yourself the fundamentals of programming with the latest version of Visual C# with Visual Studio. If you are an experienced software developer, you'll get all the guidance, exercises, and code you need to start building responsive, scalable, cloud-connected applications that can run almost anywhere. Discover how to: Quickly start creating Visual C# code and projects with Visual Studio Work with variables, operators, expressions, methods, and program flow Build more robust apps with error, exception, and resource management Spot problems fast with the Visual Studio debugger Make the most of improvements to C# methods, parameters, and switch statements Master the C# object model, and create your own functional data structures Leverage advanced properties, indexers, generics, and collection classes Create Windows 10 apps that share data, collaborate, and use cloud services Integrate Cortana to voice-enable your applications Perform complex queries over object collections with LINQ
Microsoft SharePoint : Building Office 2007 Solutions in VB 2005
Microsoft SharePoint: Building Office 2007 Solutions in VB 2005 is the third edition of Scot Hillier's market-leading SharePoint book. The new version includes extensive updates from the previous editions, with a complete focus on SharePoint 2007 and its integration with the 2007 Microsoft Office System. This edition also features new approaches for using SharePoint to improve business efficiency, plus new workflow solutions for SharePoint and BizTalk, as well as a brand new chapter on building a SharePoint solution from start to finish.
Microsoft SharePoint : Building Office 2007 Solutions in C# 2005
Microsoft SharePoint: Building Office 2007 Solutions in C# 2005 is the third edition of Scot Hilliers market-leading SharePoint book. This book features extensive updates to the previous edition, with a complete focus on SharePoint 2007 and its integration with the 2007 Microsoft Office System. It also features new approaches for using SharePoint to improve business efficiency as well as new workflow solutions for SharePoint and BizTalk, plus a new chapter on building a SharePoint solution from start to finish.
Microsoft SharePoint : Building Office 2003 Solutions
This detailed second edition is Scot Hilliers follow-up to his market-leading SharePoint book. This version includes extensive updates to the previous edition, with emphasis on Visual Studio Tools for Office 2005 and new approaches for using SharePoint to improve business efficiency. Also featured are new workflow solutions for SharePoint and BizTalk, and a new chapter on building a SharePoint solution from start to finish.
Microgravity Two-phase Flow and Heat Transfer
Multiphase thermal systems (involving more than one phase or one component) have numerous applications in aerospace, heat-exchanger, transport of contaminants in environmental systems, and energy transport and energy conversion systems. Advances in understanding the behaviour of multiphase thermal systems could lead to higher efficiency energy production systems, improved heat-exchanger design, and safer and enhanced treatment of hazardous waste. But such advances have been greatly hindered by the strong effect of gravitational acceleration on the flow. Depending on the flow orientation and the phase velocities, gravitational forces could significantly alter the flow regime, and hence the pressure-drop and heat-transfer coefficients associated with the flow. A reduced gravity environment (or "microgravity"), provides an excellent tool to study the flow without the masking effects of gravity. This book presents for the first time a comprehensive coverage of all aspects of two-phase flow behaviour in the virtual absence of gravity.



















