الصفحة 1
الصفحة 1
Novel Drug Delivery Systems for Chinese Medicines
Describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
Nonlinear Smoothing and Multiresolution Analysis
This monograph presents a new theory for analysis, comparison and design of nonlinear smoothers, linking to established practices. Although a part of mathematical morphology, the special properties yield many simple, powerful and illuminating results leading to a novel nonlinear multiresolution analysis with pulses that may be as natural to vision as wavelet analysis is to acoustics. Similar to median transforms, they have the advantages of a supporting theory, computational simplicity, remarkable consistency, full trend preservation, and a Parceval-type identity.
Nonlinear H2/H-Infinity Constrained Feedback Control : A Practical Design Approach Using Neural Networks
In this book the authors present algorithms for H2 and H-infinity design for nonlinear systems which, unlike earlier theories, provide solution techniques for the core Hamilton–Jacobi equations that yield control systems which can be implemented in real systems; neural networks are used to solve the nonlinear control design equations.
Neurology Oral Boards Review : A Concise and Systematic Approach to Clinical Practice
Rapid recall of vast amounts of factual material is the key to success in both the Neurology Oral Board examination and in everyday patient care. In Neurology Oral Boards Review: A Concise and Systematic Approach to Clinical Practice, Eroboghene E. Ubogu offers a comprehensive review of relevant topics and examination strategies needed to pass the American Board of Psychiatry and Neurology (ABPN) Part II (Oral) exam, complete with up-to-date, evidence-based guidelines on diagnosis and management in clinical neurology. The author has written the book specifically to satisfy the requirements of the ABPN, with clinical case vignettes designed to allow the examinee to localize the plausible disease process, to indicate which investigations may help in establishing a diagnosis, to deduce treatment plans, and to make a prognosis, including patient and family counseling. The emergency cases test the ability to think critically when faced with a neurological emergency, putting a premium on resuscitation, patient safety, and rapid high-yield investigations. The general neurology cases reflect the breadth of disorders experienced in hospital and outpatient settings. The author also provides a detailed description of the oral ABPN examination and suggests a study regimen that takes into account the difficulties of allotting time to prepare while in post-residency training or practice.
Napoleonic Governance in the Netherlands and Northwest Germany : Conquest, Incorporation, and Integration
This Palgrave Pivot explores the ways in which French Emperor Napoleon tried to integrate the present-day Netherlands and Northwest Germany into his Empire, by replacing traditional institutions and governing practices with French ones ('Napoleonic governance'). The northern periphery of the Napoleonic Empire continues to be overlooked by the bulk of historians; this study shows that a transregional approach can yield important findings. In a broader sense, the study does not deal with these regions alone, but also with the difficulties that are inherent to European integration.
Myosins : A Superfamily of Molecular Motors
Application of state-of-the-art cellular and molecular biological, structural biological, genetic, biochemical and biophysical techniques has provided and continues to provide critical information regarding the structure–function relationship; and the cellular roles of various myosins in organisms as diverse as protozoa, yeast, plants and higher animals. The association of myosins with diseases including neurological disorders, immu- deficiencies, cardiomyopathies, hearing and vision loss testify to the importance of understanding the biochemical properties and cellular roles of myosins. The 16 chapters in this volume summarize the tremendous progress made in studying members of the myosin superfamily in recent years and offer critical insight into what future research will yield.
Multiparadigm Programming in Mozart/Oz ; 2nd International Conference, MOZ 2004, Charleroi, Belgium, October 7-8, 2004, Revised Selected Papers
Oz's concurrency model yields simplicity and clarity (because Oz makes it easier to express complex programs with many interacting components), g- erality, and better interfaces (because the data?ow model automatically makes interfaces more lightweight). Constraint programming in Oz again yields simplicity and clarity (because theprogrammercanexpresswhatneedstobetrueratherthanthemorecomplex issue of how to make it true), and o?ers a powerful mathematical notation that is di?cult to implement on top of languages that do not support it natively. Mozart's distributed computing model makes for improved interfaces and eases the evolution of systems. In my own work, one of the most important concernsistobeabletoquicklyscaleupaprototypeimplementationintoalar- scale service that can run reliably on thousands of computers, serving millions of users.
Molecular genetics, structures, mechanisms, and functions : Applications and exploring the nucleus ; Vol.2
Continues the coverage of generic engineering, dealing with the concept of genes, their relationship with chromosomes, and their functional manifestation to the benefit of organisms at large and for human in particular. Topics include Mendel’s Laws of Inheritance, which explains the inheritance of traits visible through generations; , genome diversity and evolution genetic protein synthesis, recombination and evolution of DNA, transposable elements in genetics, chromosomal aberrations, and more. The volume also addresses genetic engineering in agricultural science for increased crop yields, to reduce costs for food or drug production, to reduce the need for pesticides, to enhance crop quality, etc.
Modelling water and nutrient dynamics in soil-crop systems : Applications of different models to common data sets - Proceedings of a workshop held 2004 in Müncheberg, Germany
This book contains articles from a workshop on "Modelling water and nutrient dynamics in crop-soil systems". Data sets from lysimeters and experimental fields of multiyear crop rotations were provided for modellers. A unique data set is provided of a 100 year long term field experiment regarding crop yield and organic carbon development under different management systems. The book includes a detailed description of data sets which can be used by modellers and the papers describe the applications of 18 different modelling approaches describing soil-crop-atmosphere interactions for water, nitrogen and carbon dynamics.
Misleading marketing communication : Assessing the impact of potentially deceptive food labelling on consumer behaviour
Presenting four complementary experimental studies targeting recurrent grey-zone scenarios on the Danish food market, the book illustrates the potential of the so-called ShopTrip test paradigm which simulates and registers real-life e-shopping behaviour as it unfolds while yielding new types of data against which opposing assessments of potential misleadingness can be matched. The results are discussed in the light of possible paths of theoretical explanation and implications for future regulative practices, including companies’ self-regulation.
Minimally invasive periodontal therapy : Clinical techniques and visualization technology
The long-term success of periodontal therapy is dependent on proper diagnosis and removal of subgingival tooth-borne accretions in the form of calculus and bacteria. From a clinical perspective, better visualization during the diagnostic and therapeutic phases has been shown to yield better results compared to traditional approaches.Minimally Invasive Periodontal Therapy evaluates the advantages of using minimal invasive techniques, the technologies available for enhancing visualization during minimally invasive therapy, and step-by-step illustrates the clinical use of each technique.
Mechanics of biomaterials : Fundamental principles for implant design
Teaching mechanical and structural biomaterials concepts for successful medical implant design, this self-contained text provides a complete grounding for students and newcomers to the field. Split into three sections: Materials, Mechanics and Case Studies, it begins with a review of sterilization, biocompatibility and foreign body response before presenting the fundamental structures of synthetic biomaterials and natural tissues. Mechanical behavior of materials is then discussed in depth, covering elastic deformation, viscoelasticity and time-dependent behavior, multiaxial loading and complex stress states, yielding and failure theories, and fracture mechanics. The final section on clinical aspects of medical devices provides crucial information on FDA regulatory issues.
Mathematical Models of Distribution Channels
In Chapters 1 and 2 the authors provide an introduction to the current, analytical literature on distribution channels, and they present an intuitively appealing prologue to the Channel Myths that are developed rigorously in later Chapters. In Chapters 3, 4, and 10 they extend the literature by ascertaining the relationship between the manufacturer-optimal wholesale-price strategy and channel breadth. Specific analyses include multiple, non-competing retailers, multiple states-of-nature, and multiple, competing retailers. In Chapters 5-7 the authors determine the profitability of various wholesale-price strategies; this analysis culminates in Chapters 8 and 9 with the determination of the (very limited) conditions under which channel coordination can be optimal for the manufacturer. In Chapter 11 they prove that existing methods of measuring the effect of a change in the degree of inter-retailer substitutability are totally misleading. They then develop an original, theoretical basis for measuring the impact of a change in the degree of inter-retailer substitutability that yields insightful, intuitively appealing results. In Chapter 12 the authors set forth an agenda for future research based on a meta-model that embraces all existing models in the literature. They also issue an appeal for creation of a "Unifying Theory of Distribution Channels" that will enable researchers to work independently and yet to contribute toward the common goal of deepening the marketing science professions’ understanding of distribution channels.
Iron Nutrition in Plants and Rhizospheric Microorganisms
This book uses an interdisciplinary approach to provide a comprehensive review on the status of iron nutrition in plants. International scientists discuss research on acquisition of iron by strategy I and strategy II plants. These reviews summarize a variety of plant species and include both laboratory and field observations. Topics covered in this book include: plants as a source of iron for animals and humans, iron translocation in the plants, iron-stimulated activities that influence crop yield and fruit tree productivity, iron uptake by plants as influenced by microorganisms (i.e. free living soil microorganisms, symbiotic nitrogen-fixing and pathogenic bacteria), the role of plant hormones in iron transport, iron-metal competition in phytoremediation, root zone activities involving interactions between minerals and organic matter, the role of microbial siderophores in rhizospheric iron cycling, iron storage as phytoferritin, proteomic and metabolic studies associated with iron stress response, methods for studying iron metabolism including stable isotopes, and the correction of iron deficiency through the use of synthetic or natural chelates.
Introduction to Symplectic Dirac Operators
One of the basic ideas in differential geometry is that the study of analytic properties of certain differential operators acting on sections of vector bundles yields geometric and topological properties of the underlying base manifold. Symplectic spinor fields are sections in an L^2-Hilbert space bundle over a symplectic manifold and symplectic Dirac operators, acting on symplectic spinor fields, are associated to the symplectic manifold in a very natural way. Hence they may be expected to give interesting applications in symplectic geometry and symplectic topology. These symplectic Dirac operators are called Dirac operators, since they are defined in an analogous way as the classical Riemannian Dirac operator known from Riemannian spin geometry. They are called symplectic because they are constructed by use of the symplectic setting of the underlying symplectic manifold. This volume is the first one that gives a systematic and self-contained introduction to the theory of symplectic Dirac operators and reflects the current state of the subject. At the same time, it is intended to establish the idea that symplectic spin geometry and symplectic Dirac operators may give valuable tools in symplectic geometry and symplectic topology,
Internet of Things and Machine Learning in Agriculture
Machine Learning (ML) and the Internet of Things (IoT) can play a very promising role in the agricultural industry. Some examples include: an AI-powered drone to monitor the field, an IoT-designed automated crop watering system, sensors embedded in the field to monitor temperature and humidity, etc. The agriculture industry is the largest in the world, but when it comes to innovation there is a lot more to explore. IoT devices can be used to analyze the status of crops. For instance, with soil sensors, farmers can detect any irregular conditions such as high acidity and efficiently tackle these issues to improve their yield. In this book, we will point out the challenges facing the agro-industry that can be addressed by ML and IoT and explore the impacts of these technologies in the agriculture sector.
Integral Methods in Science and Engineering : Techniques and Applications
The physical world is studied by means of mathematical models, which consist of differential, integral, and integro-differential equations accompanied by a large assortment of initial and boundary conditions. In certain circumstances, such models yield exact analytic solutions. When they do not, they are solved numerically by means of various approximation schemes. Whether analytic or numerical, these solutions share a common feature: they are constructed by means of the powerful tool of integration—the focus of this self-contained book. This work illustrates the application of integral methods to diverse problems in mathematics, physics, biology, and engineering. The thirty two chapters of the book, written by scientists with established credentials in their fields, contain state-of-the-art information on current research in a variety of important practical disciplines.
Integrable Systems in Celestial Mechanics
This work presents a unified treatment of three important integrable problems relevant to both Celestial and Quantum Mechanics. Under discussion are the Kepler (two-body) problem and the Euler (two-fixed center) problem, the latter being the more complex and more instructive, as it exhibits a richer and more varied solution structure. Further, because of the interesting investigations by the 20th century mathematical physicist J.P. Vinti, the Euler problem is now recognized as being intimately linked to the Vinti (Earth-satellite) problem. Here the analysis of these problems is shown to follow a definite shared pattern yielding exact forms for the solutions. A central feature is the detailed treatment of the planar Euler problem where the solutions are expressed in terms of Jacobian elliptic functions, yielding analytic representations for the orbits over the entire parameter range.
Information — Consciousness — Reality : How a New Understanding of the Universe Can Help Answer Age-Old Questions of Existence
This book chronicles the rise of a new scientific paradigm offering novel insights into the age-old enigmas of existence. It is explores a radical paradigm shift uncovering the ontology of reality. It is found to be information-theoretic and participatory, yielding a computational and programmable universe.
IMPROVE - Innovative modelling approaches for production systems to raise validatable efficiency : Intelligent methods for the factory of the future
This open access work presents selected results from the European research and innovation project IMPROVE which yielded novel data-based solutions to enhance machine reliability and efficiency in the fields of simulation and optimization, condition monitoring, alarm management, and quality prediction.
