الصفحة 1
الصفحة 1
Nicotinic Acetylcholine Receptor Signaling in Neuroprotection
Presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology.
Ecology of Harmful Algae
Harmful algal blooms are one of the consequences of the human impact on aquatic ecosystems, particularly the process of eutrophication. They can cause a variety of deleterious effects, including the poisoning of fish and shellfish, habitat disruptions for many organisms, water discolouration, beach fouling, and even toxic effects for humans. This volume is a comprehensive synthesis of the latest research achievements concerning harmful algae (HA) ecology. International experts provide an in-depth analysis of HA topics including: global distribution, ecology of major HA groups, ecology and physiology of HA, HA and the food web, studying and mitigating HA, the human impact on HA and HA impact on human activity. This volume is an invaluable source of information for researchers in HA ecology as well as for advanced students, lecturers, and environmental managers.
Drug-Induced Oral Complications
Provides detailed information on the prevalence and manifestations of the most important oral complications associated with different drug treatments, focusing especially on recently developed therapies. Among the diverse adverse drug reactions covered are gingival overgrowth, ulcerations, lichenoid reactions, pigmentation, and bullous reactions. The potential direct toxic effects on bone of drugs that prevent bone mass loss, such as bisphosphonates and denosumab, are fully examined, as is the occurrence of spontaneous oral bleeding in patients receiving antithrombotic therapies. Further chapters focus on drug-induced taste disorders and salivary gland disturbances, including xerostomia, swelling, and hypersalivation. The enhanced risk of oral infections when using chemotherapy and biotherapy is addressed, and the closing chapter examines drug-related perioral and facial complications. This book is a collaborative work that brings together clinicians, surgeons, and specialists in drug safety surveillance.
Dangerous of Pharmaceutical Waste From Hospitals and Homes on Human and Environment
The occurrence of pharmaceuticals in environment originating from hospitals and household waste has received increased scientific attention during the last decades because more than 100 different drugs have been detected in the aquatic environment at concentrations from the nanogram (ng) to the μg/l range. This research talk about improper disposal of pharmaceutical waste, impacts of some drugs included in like metals, endocrine disruptors, and various compounds that are dangerous for aquatic and human lives. The safe disposal and management of pharmaceutical waste. The origin of this problem begin due to lack of awareness about this issues beside there is no training or courses for pharmacists and people work in medical departments on pharmaceutical waste management during their academic studies.in addition, this research also talk about how to reduce the amount of pharmaceuticals waste and environmentally friendly and cost-effective ways for handling this waste, beside increase the awareness to overcome this problem.
Biochemical Mechanisms of Detoxification in Higher Plants : Basis of Phytoremediation
Plants play a key role in purifying the biosphere of the toxic effects of industrial activity. This book shows how systematic application of the results of investigations into the metabolism of xenobiotics (foreign, often toxic substances) in plants could make a vastly increased contribution to planetary well-being. Deep physiological knowledge gained from an accumulation of experimental data enables the great differences between the detoxifying abilities of different plants for compounds of different chemical nature to be optimally exploited. Hence planting could be far more systematically adapted to actual environmental needs than is actually the case at present.
Advances in the toxicity of construction and building materials
Presents the potential and toxic effects of building materials on human health, along with tactics on how to minimize exposure. Chapters are divided into four sections covering the toxicity of indoor environments, fire toxicity, radioactive materials, and toxicity from plastics, metals, asbestos, nanoparticles and construction wastes. Key chapters focus on the reduction of chemical emissions in houses with eco-labelled building materials and potential risks posed by indoor pollutants that may include volatile organic compounds (VOC), formaldehyde, semi-volatile organic compounds (SVOC), radon, NOx, asbestos and nanoparticles.
