الصفحة 1
الصفحة 1
Open Quantum Systems II : The Markovian Approach
These books present in a self-contained way the mathematical theories involved in the modeling of such phenomena. They describe physically relevant models, develop their mathematical analysis and derive their physical implications. Volume II is dedicated to the Markovian formalism of classical and quantum open systems. A complete exposition of noise theory, Markov processes and stochastic differential equations, both in the classical and the quantum context, is provided. These mathematical tools are put into perspective with physical motivations and applications.
Open access databases and datasets for drug discovery
With an overview of 90 freely accessible databases and datasets on all aspects of drug design, development, and discovery, Open Access Databases and Datasets for Drug Discovery is a comprehensive guide to the vast amount of “free data” available to today’s pharmaceutical researchers. The applicability of open-source data for drug discovery and development is analyzed, and their usefulness in comparison with commercially available tools is evaluated. The most relevant databases for small molecules, drugs and druglike substances, ligand design, protein 3D structures (both experimental and calculated), and human drug targets are described in depth, including practical examples of how to access and work with the data. The first part is focused on databases for small molecules, followed by databases for macromolecular targets and diseases. The final part shows how to integrate various open-source tools into the academic and industrial drug discovery and development process.
Ontology Management : Semantic Web, Semantic Web Services, and Business Applications
This volume describes relevant tasks, practical and theoretical challenges, limitations and methodologies, plus available software tools. The editors discuss integrating the conceptual and technical dimensions with a business view on using ontologies, by stressing the cost dimension of ontology engineering and by providing guidance on how up-to-date tooling helps to build, maintain, and use ontologies. Also included is a one-stop reference on all aspects of managing ontological data and best practices on ontology management for a number of application domains.
On the move to meaningful internet systems 2007 : CoopIS, DOA, ODBASE, GADA, and IS ; OTM Confederated International Conferences, CoopIS, DOA, ODBASE, GADA, and IS 2007, Vilamoura, Portugal, November 25-30, 2007, Proceedings, Part I
Constitutes the proceedings of the 5 confederated international conferences on Cooperative Information Systems, Distributed Objects and Applications, Ontologies, Databases and Applications of Semantics, Grid computing, high performance and Distributed Applications, and Information Security held as OTM 2007 in Vilamoura, Portugal, in November 2007.
Objects, Components, Models and Patterns ; 46th International Conference, TOOLS EUROPE 2008, Zurich, Switzerland, June 30 - July 4, 2008. Proceedings
This book constitutes the thoroughly refereed proceedings of the 46th International Conference on Objects, Components, Models and Patterns, TOOLS EUROPE 2008, held in Zurich, Switzerland, in June/July 2008.TOOLS played a major role in the spread of object-oriented and component technologies. It has now broadened its scope beyond the original topics of object technology and component-based development to encompass all modern, practical approaches to software development.
Object-Oriented Software Engineering Using UML Patterns and Java
Shows students how to use both the principles of software engineering and the practices of various object-oriented tools, processes, and products. Using a step-by-step case study to illustrate the concepts and topics in each chapter, Bruegge and Dutoit emphasize learning object-oriented software engineer through practical experience: students can apply the techniques learned in class by implementing a real-world software project. The third edition addresses new trends, in particular agile project management (Chapter 14 Project Management) and agile methodologies (Chapter 16 Methodologies).
Obesity Management in Family Practice
With guidelines backed by the best scientific data, the book is about application, not just theory. The reader is given the commonsense tools that patients need in order to have ownership of their disease. Ultimately, patients are empowered to control their obesity, resulting in positive interaction between providers and patients.
Nutrigenomics and nutraceuticals
Provides an authoritative and comprehensive overview of the field of nutraceuticals and genomics—also called nutrigenomics, a rapidly growing field. It discusses both nutrigenomic and nutrigenetic techniques to investigate the nutritional basis of several health disorders because scientists have found that diet can affect gene expression. The book covers the nutrigenomic tools for the prevention of disease conditions such as cancer, viral infection, microbial infection, COVID-19, HIV/AIDS, tuberculosis, hypertension, neurodegenerative disease, obesity, baldness, and anemia. Some nutrigenomic tools that can also be used for brain health, weight loss, human nutrition, skin care, and maintaining health during pregnancy are also explored.
Nutraceuticals in arthritis and psoriasis : Management and prevention of diseases
Explores plant-derived nutraceuticals that can be used as crucial therapeutic tools in the prevention and treatment of arthritis and psoriasis, providing detailed information on the use of plant-derived nutraceuticals, such as microalgae and other marine botanicals, omega polyunsaturated fatty acids, glucosamine and chondroitin sulphate, plant-based gum, vitamins and oils, probiotic supplements, and others in the treatment and management of arthritis and psoriasis. The book relates the recent scientific evidence on the effectiveness of each of these nutraceutical treatments, offering case studies, results of clinical studies, and more.
Nutraceuticals and obesity strategies for weight management
his comprehensive volume explores the role that nutraceuticals can play in addressing obesity, shedding light on their potential as tools to promote sustainable weight management strategies as well as addressing associated health risks. Delving into the intricate interplay between nutrition, health, and obesity, the book provides a compelling account that illustrates how nutraceutical interventions can be incorporated into holistic obesity management strategies. It begins with an account of the mechanisms by which nutraceuticals function before featuring chapters on their efficacy and safety, how they can be integrated with other therapeutic interventions, and how they can be tailored for individuals with comorbidities. Offering a global perspective on the issue, there is also coverage of the various regulatory contexts in which nutraceuticals are sold and used.
Numerical Solution of Partial Differential Equations on Parallel Computers
The scientific fields of Ma- ematics and Physics provide a powerful vehicle for such descriptions in terms of Partial Differential Equations (PDEs). Formulated as such equations, physical laws can become subject to computational and analytical studies. In the computational setting, the equations can be discreti ed for ef?cient solution on a computer, leading to valuable tools for simulation of natural and man-made processes. Numerical so- tion of PDE-based mathematical models has been an important research topic over centuries, and will remain so for centuries to come. In the context of computer-based simulations, the quality of the computed results is directly connected to the model’s complexity and the number of data points used for the computations. Therefore, computational scientists tend to ?ll even the largest and most powerful computers they can get access to, either by increasing the si e of the data sets, or by introducing new model terms that make the simulations more realistic, or a combination of both. Today, many important simulation problems can not be solved by one single computer, but calls for parallel computing.
Numerical Continuation Methods for Dynamical Systems : Path following and boundary value problems
The book opens with a foreword by Herbert B. Keller and lecture notes by Sebius Doedel himself that introduce the basic concepts of numerical bifurcation analysis. The other chapters by leading experts discuss continuation for various types of systems and objects and showcase examples of how numerical bifurcation analysis can be used in concrete applications. Topics that are treated include: interactive continuation tools, higher-dimensional continuation, the computation of invariant manifolds, and continuation techniques for slow-fast systems, for symmetric Hamiltonian systems, for spatially extended systems and for systems with delay. Three chapters review physical applications: the dynamics of a SQUID, global bifurcations in laser systems, and dynamics and bifurcations in electronic circuits.
Number Theory ; Vol. II : Analytic and Modern Tools
The central theme of this graduate-level number theory textbook is the solution of Diophantine equations, i.e., equations or systems of polynomial equations which must be solved in integers, rational numbers or more generally in algebraic numbers. This theme, in particular, is the central motivation for the modern theory of arithmetic algebraic geometry. In this text, this is considered through three aspects.
Number Theory ; Vol. I : Tools and Diophantine Equations
The central theme of this graduate-level number theory textbook is the solution of Diophantine equations, i.e., equations or systems of polynomial equations which must be solved in integers, rational numbers or more generally in algebraic numbers. This theme, in particular, is the central motivation for the modern theory of arithmetic algebraic geometry. In this text, this is considered through three aspects.
Nucleic Acids Hybridization : Modern Applications
Several approaches, such as microarray hybridization, have become extremely popular tools for specialists in biochemistry and biomedicine, while the potential of many other advantageous techniques seems to be underestimated. Written by an international team of authors, this book details the current state-of-art in hybridization techniques. Coverage includes experimental protocols along with comprehensive and detailed method descriptions.
Novel Plant Imaging and Analysis : Water, Elements and Gas, Utilizing Radiation and Radioisotopes
This book is only an introduction to show that radiation and radioisotopes (RI) are premier tools to study living plant physiology which leads to new findings. Who had ever imagined that we could see water in a plant? Who had ever imagined that we could see ions moving toward roots in solution? Who had ever imagined that we could see invisible gas (CO2) fixation and movement in a plant? These studies demonstrated for the first time that water, ions and gas can be visualized in living plants, which could be hardly seen by anyone before. This publication summarizes the results obtained by Nakanishi’s lab in The Univ. of Tokyo, based on her original concept and her original tools or systems. It is useful for professional scientists, plant physiologist, and those studying plant imaging.
Nonunion of the Long Bones : Diagnosis and treatment with compression-distraction techniques
The primary purpose of this book is to discuss currently available tools for diagnosing long bone nonunions, to illustrate the means of prevention, and to specify the indications for management using compression-distraction techniques.
Nonsmooth Mechanics and Analysis : Theoretical and Numerical Advances
Nonsmooth mechanics concerns mechanical situations with possible nondifferentiable relationships, eventually discontinuous, as unilateral contact, dry friction, collisions, plasticity, damage, and phase transition. The basis of the approach consists in dealing with such problems without resorting to any regularization process. Indeed, the nonsmoothness is due to simplified mechanical modeling; a more sophisticated model would require too large a number of variables, and sometimes the mechanical information is not available via experimental investigations. Therefore, the mathematical formulation becomes nonsmooth; regularizing would only be a trick of arithmetic without any physical justification. Nonsmooth analysis was developed, especially in Montpellier, to provide specific theoretical and numerical tools to deal with nonsmoothness. It is important not only in mechanics but also in physics, robotics, and economics.
Nonsmooth Analysis
The book treats various concepts of generalized derivatives and subdifferentials in normed spaces, their geometric counterparts (tangent and normal cones) and their application to optimization problems. It starts with the subdifferential of convex analysis, passes to corresponding concepts for locally Lipschitz continuous functions and finally presents subdifferentials for general lower semicontinuous functions. All basic tools are presented where they are needed; this concerns separation theorems, variational and extremal principles as well as relevant parts of multifunction theory. The presentation is rigorous, with detailed proofs. Each chapter ends with bibliographic notes and exercises.
Nonparametric Functional Data Analysis : Theory and Practice
Modern apparatuses allow us to collect samples of functional data, mainly curves but also images. On the other hand, nonparametric statistics produces useful tools for standard data exploration. This book links these two fields of modern statistics by explaining how functional data can be studied through parameter-free statistical ideas. This book starts from theoretical foundations including functional nonparametric modeling, description of the mathematical framework, construction of the statistical methods, and statements of their asymptotic behaviors. It proceeds to computational issues including R and S-PLUS routines. Several functional datasets in chemometrics, econometrics, and pattern recognition are used to emphasize the wide scope of nonparametric functional data analysis in applied sciences. The companion Web site includes R and S-PLUS routines, command lines for reproducing examples presented in the book, and the functional datasets. Rather than set application against theory, this book is really an interface of these two features of statistics. A special effort has been made in writing this book to accommodate several levels of reading.
