الصفحة 1
الصفحة 1
Zinc Finger Proteins: From Atomic Contact to Cellular Function
The scientists discovered a novel domain associated with zinc, and named this domain "zinc finger. " The number of proteins with similar zinc fingers grew quickly and these proteins are now called C2H2, Cys2His2 or classical zinc finger proteins. To date, about 24,000 C2H2 zinc finger proteins have been recognized. Approximately 700 human genes, or more than 2% of the genome, have been estimated to encode C2H2 finger proteins. From the beginning these proteins were thought to be numerous, but no one could have predicted such a huge number. Perhaps thousands of scientists are now working on C2H2 zinc finger proteins fi-om variou s viewpoints. This field is a good example of how a new science begins with the insight of a few scientists and how it develops by efforts of numerous independent scientists, in contrast to a policy-driven scientific project, such as the Human Genome Project, with goals clearly set at its inception and with work performed by a huge collaboration throughout the world. As more zinc finger proteins were discovered, several subfamilies, such as C2C2, CCHC, CCCH, LIM, RING, TAZ, and FYVE emerged, increasing our understanding of zinc fingers. The knowledge was overwhelming. Moreover, scientists began defining the term "zinc finger" differently and using various names for identical zinc fingers.
Zebrafish : Methods and protocols
Introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the vertebrate nervous system, tools and approaches using zebrafish to study stem cell and regenerative biology, as well as techniques in genetics and genomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.
Your Post has been Removed : Tech Giants and Freedom of Speech
This book argues established democratic norms for freedom of expression should be implemented on the internet. Moderating policies of tech companies as Facebook, Twitter and Google have resulted in posts being removed on an industrial scale.
Yerba mate is a natural alternative of ozempic
Yerba mate (Ilex paraguariensis), a traditional South American herbal tea, has gained attention as a potential natural alternative to Ozempic (semaglutide), a pharmaceutical drug used for weight management and type 2 diabetes. Rich in bioactive compounds like caffeine, theobromine, chlorogenic acids, and saponins, yerba mate exhibits appetitesuppressing, metabolism-boosting, and glucose-regulating properties. Studies suggest that yerba mate may enhance satiety, promote fat oxidation, and improve insulin sensitivity, mimicking some effects of GLP-1 receptor agonists like Ozempic—but with fewer side effects
Yeasts in Food and Beverages
This book provides a comprehensive account of the ecology, physiology, biochemistry, molecular biology, and genomics of the diverse range of yeast species associated with the production of foods and beverages.
Yearbook of Morphology 2005
In the Yearbook of Morphology 2005 a number of important theoretical issues are discussed: the role of inflectional paradigms in morphological analysis, the differences between words and affixes, and the adequacy of competing models of word structure.In addition, the role of phonological factors in shaping complex words is discussed.Evidence for particular positions defended in this volume is taken from a wide variety of languages.This volume is of interest to those working in theoretical, descriptive and historical linguistics, morphologists, phonologists, computational linguists, and psycholinguists.
Xylem : Methods and protocols
Provides detailed techniques used for the study and characterization of the plant vascular system, with a central focus on the xylem tissue. Chapters are organized in three main sections covering; analysis of xylem development, xylem characterization though imaging techniques, and analysis of the xylem composition. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
X-rays for Archaeology
This book offers physicists, art historians, archaeologists, curators, and conservators a detailed overview via contributions written by leading scientists in the field. The book contains scientific data, i.e. in situ measurement data taken with portable XRF and XRD, and fine data taken with accelerating ion beams and synchrotron radiations, together with their explanations. Results obtained by traditional scientific methods are also reviewed. The broad data collection spans experimental data taken both from monuments in the field and exhibits in museums.Also included are data from glazes, ancient gold and silver coins, gold jewelleries, gold alloys, corroded metals, gemstones (ruby, emerald and garnet), painting pigments, pottery, bronze, obsidian, stucco, turquoise, and so on.
X-Ray Contrast Media : Overview, use and pharmaceutical aspects
An overview on CT/X-ray contrast media designed for radiologists and other medical specialists who use contrast media in imaging and interventional procedures as well as related scientists on the use and pharmaceutical aspects of X-ray contrast media. The overall goal of this book is to provide a comprehensive overview relevant for the optimal use of x-ray contrast media covering next to the historic development, their structure and properties also practical information for handling of contrast media, and explanation of the relevant risks during use and measures for prevention and treatment of potential side effects.
Writing Manuals for the Masses : The Rise of the Literary Advice Industry from Quill to Keyboard
This collection of essays examines the literary advice industry since its emergence in Anglo-American literary culture in the mid-nineteenth century within the context of the professionalization of the literary field and the continued debate on creative writing as art and craft. Often dismissed as commercial and stereotypical by authors and specialists alike, literary advice has nonetheless remained a flourishing business, embodying the unquestioned values of a literary system, but also functioning as a sign of a literary system in transition. Exploring the rise of new online amateur writing cultures in the twenty-first century, this collection of essays considers how literary advice proliferates globally, leading to new forms and genres.
Writing in Context(s) : Textual Practices and Learning Processes in Sociocultural Settings
The premise that writing is a socially-situated act of interaction between readers and writers is well established. This volume first, corroborates this premise by citing pertinent evidence, through the analysis of written texts and interactive writing contexts, and from educational settings across different cultures from which we have scant evidence. Secondly, all chapters, though addressing the social nature of writing, propose a variety of perspectives, making the volume multidisciplinary in nature. Finally, this volume accounts for the diversity of the research perspectives each chapter proposes by situating the plurality of terminological issues and methodologies into a more integrative framework. Thus a coherent overall framework is created within which different research strands (i.e., the sociocognitive, sociolinguistic research, composition work, genre analysis) and pedagogical practices developed on L1 and L2 writing can be situated and acquire meaning.
Wrist Arthroscopy
Dr. William B. Geissler has selected an international group of experts to compose this practical guide to wrist arthroscopy that is a comprehensive reference for both orthopedic residents new to the field and for experienced orthopedic surgeons looking to refine their technique. The book covers fundamental topics, such as arthroscopic anatomy and the proper evaluation of wrist pain, before advancing to thorough discussions of electrothermal shrinkage, arthroscopy of the thumb and small joints of the hand, and specific diagnoses for an array of common injuries. Orthopedists will appreciate the emphasis that this book places on the treatment of wrist disorders. Current minimally invasive procedures are described in detail, including management of carpal instability, new techniques in arthroscopic repair of TFCC tears, and arthroscopic excision of both volar and dorsal wrist ganglia. Tips and tricks are highlighted that make implementing new techniques easier.
Wound Healing and Ulcers of the Skin : Diagnosis and Therapy - The Practical Approach
Not only written by experts but the content of each of the chapters has also been peer-reviewed.- Presents a step-by-step approach to the treatment of chronic wounds.- For dermatologists, but also many other medical disciplines such as general practitioners and family physicians who also treat chronic wounds
World Spice Plants : Economic Usage, Botany, Taxonomy
This book addresses the need to disseminate scientific knowledge of the complex world of spice plants to a wide audience of interest. It considers the economic usage of spices in several forms, as an ingredient for adding flavor, as a pot herb and as an additive for condiments such as ketchup, and mustard. The book is aimed primarily at aroma experts in both science and industry, but also botanists, pharmacists, food chemists and dieticians will take inspiration from the book, which is also illustrated by around 100 full color photographs. Comprehensive listing of over 1400 plants / Plant nomenclature from around the world / Arranged alphabetically for ease of reference / Exhaustive register of relevant literature for further reading
Workflows for e-Science : Scientific Workflows for Grids
Workflows for e-Science presents an overview of the current state of the art in the field. It brings together research from many leading computer scientists in the workflow area and provides real world examples from domain scientists actively involved in e-Science. The computer science topics addressed in the book provide a broad overview of active research focusing on the areas of workflow representations and process models, component and service-based workflows, standardization efforts, workflow frameworks and tools, and problem solving environments and portals.
Words and Intelligence II : Essays in Honor of Yorick Wilks
This book celebrates the work of Yorick Wilks from the perspective of his peers. It consists of original chapters each of which analyses an aspect of his work and links it to current thinking in that area. His work is pertinent to recent developments in language processing such as the Semantic Web.
Wood and wood joints building traditions in Europe, Japan and China
Wood and Wood Joints puts today s world in touch with the diverse know-how of Western and Eastern cultures about the creative use of this distinctive material. A holistic perspective generates an appreciation of building with wood that will inform professionals, give building specialists a new sense of an almost vanished world, and simply fascinate the lay public.
Wonder Wood : A Favorite Material for Design, Architecture and Art
Presents this timeless material as it is being used today and how it can be used in the future. It also documents a selection of current international projects and processes, making-ofs, and experiments by 120 internationally renowned designers, architects, and artists, whose creative and innovative approach to the material makes their work compelling. For selected projects, interviews with the designers provide an in-depth look at the creative process and its results. A second section, dedicated to materials and technologies examines innovative developments as well as wood, wood-based materials, finishing technologies, and wooden structure principles.
Women, Migration and Gendered Experiences : The Case of Post-1991 Albanian Migration
This book focuses on Albanian internal and international female migration and places gender at the heart of postsocialist transformation. It explores the vulnerabilities that arise for female citizens from the contradictory policies produced by the Albanian state. By illuminating the intersection of gender and migration, it shows how Albanian women are likely to embed themselves in complex social relations and migration trajectories.
Women in Biotechnology : Creating Interfaces
Women in Biotechnology presents a unique study of the relationships and communications between women scientists, particularly those working in biotechnology. This is achieved by creating interfaces or collecting different points of view over several disciplines (i.e. economy, sociology, biology, genetics) to bridge the communication gap among science, the humanities and different feminist groups. The publication of this book is the first step in building a new scientific community that shares a common interest in improving the awareness of women scientists who are not an integral part of the decision-making processes in their respective fields. In this respect, Women in Biotechnology endeavours to address the ethical and bio-political implications in the different branches of contemporary research, and to promote the need of women holding decision-making power to consolidate the scientific and social responsibility to all scientists.
