الصفحة 1
الصفحة 1
RNA Interference
The use of RNA interference (RNAi) to evoke gene silencing in mammalian cells has almost become routine laboratory practice. Through refinement of double-stranded RNA (dsRNA) triggers of RNAi and creation of genome-scale libraries, the first genome-wide loss of function screens have been carried out in mammals. This review discusses some of the key features of RNAi in mammalian systems.
RNA based therapeutics
The development of therapeutics to treat human disease has always been a major goal for biomedical research and innovation. Nevertheless, the complexity of the majority of human diseases poses an important and difficult obstacle to overcome. Moreover, the genetic contribution to these conditions complicates the targeting of endogenous and normal processes of cellular functioning, such as transcription and translation...
Integrated Management and Biocontrol of Vegetable and Grain Crops Nematodes
The second volume of the IMPD series describes aspects related to most important phytoparasitic nematodes, considering the integration of biological control methods with other management practices and technologies, including the use of predatory nematodes and microbial rhizosphere antagonists. Chapters cover topics like the mode of action and interactions of nematophagous fungi, the efficacy of controll and management of plant parasitic nematode communities through a soil conservation approach, and exploitation of nematodes-bacteria antagonistic relationships.
