الصفحة 1
الصفحة 1
Viral Therapy
Virotherapy is a treatment using biotechnology to convert viruses into therapeutic agents by reprogramming viruses to treat diseases. There are three main branches of virotherapy: anti-cancer oncolytic viruses, viral vectors for gene therapy and viral immunotherapy. These branches utilize three different types of treatment methods: gene overexpression, gene knockout, and suicide gene delivery. Gene overexpression adds genetic sequences that compensate for low to zero levels of needed gene expression. Gene knockout utilizes RNA methods to silence or reduce expression of disease-causing genes. Suicide gene delivery introduces genetic sequences that induce an apoptotic response in cells, usually to kill cancerous growths. In a slightly different context, virotherapy can also refer more broadly to the use of viruses to treat certain medical conditions by killing pathogens like Bacteriophages that specialized to kill Bacteria without harming human cell.
Therapeutic approaches in cancer treatment
A unique blend of structured information covering a broad area relevant to cancer therapeutics.This book comprises fourteen chapters covering cancer genomic approaches for cancer treatment, traditional modalities, chemotherapy, radiotherapy, hormonal therapy, immunotherapy, oncolytic virotherapy, which is another emerging field. Furthermore, it also covers targeted therapies in personalized medicine, which is again an emerging yet promising field for cancer treatment. Use of nanocarriers in the cancer treatment is another important aspect which is a developing thrive. This book is also unique about in covering psychological elements in cancer treatments and providing knowledge for nutritional assessments in cancer treatment. The book has very good text highlighting the important features with a blend of traditional and emerging treatment modalities. Furthermore, chemoresistance development and challenges it poses in cancer treatment along with the pharmacogenetics of anticancer drug, which is way important for the clinicians to understand for their individual patients, associated toxicities, and clinical responses to a particular drug.
Breast cancer genetics, immunology, and immunotherapy : An interdisciplinary approach
Publishes comprehensive volumes on immune and genetic mechanisms of breast cancer diagnosis and prognosis. The role of molecular genetics, interleukins, chemokine receptor, and tumor-infiltrated lymphocytes-TILS in breast cancer are explained. Targeting myeloid determinants, SiRNA loaded in drug delivery nanosystems, nucleic acid and drug dual agent nanoplatforms, and oncolytic virotherapy are also discussed in the treatment of breast cancer, particularly in multidrug resistant and metastatic breast cancer.
