الصفحة 1
الصفحة 1
Zebrafish : Methods and protocols
Introduces new tools, models, and analytic insights that position the zebrafish even more strongly as an engine of discovery for developmental and disease biology. Beginning with a section exploring detailed methods for use of zebrafish to model a variety of human diseases, the book continues by illuminating the key ongoing role of the fish model in studies of the vertebrate nervous system, tools and approaches using zebrafish to study stem cell and regenerative biology, as well as techniques in genetics and genomics. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls.
What is Drug Addiction?
Drug addiction is A socially common term and medically means Dependence that is a complex neurobiological disease that requires integrated treatment of the mind, body, and spirit. It is considered a brain disease because drugs change the brain, they change its structure and how it works. Without treatment, these brain changes can be long-lasting, Addiction is chronic, progressive, and if left untreated, it can be fatal. Individuals struggling with drug addiction often feel as though they cannot function normally without their drugs. This can lead to a wide range of issues that impact addictive daily life, personal relationships, and overall health. Over time, these serious side effects can be progressive, and if left untreated, it will lead to death.
Weißbuch Multiple Sklerose : Versorgungssituation in Deutschland = Multiple sclerosis white paper : Supply situation in Germany
Multiple sclerosis (MS) is the most common inflammatory degenerative disease of the central nervous system in young adults. To date, the disease cannot be cured. A number of new therapeutic options have emerged in recent years. The aim of this white paper is to present current knowledge about the disease MS and its care in Germany objectively and comprehensively. It contains Information on the clinical picture, on the epidemiology and on its health-economic relevance. Current developments and treatment recommendations are compared to the real use and the existing capacities of diagnostic and therapeutic options.
Web Intelligence Meets Brain Informatics ; 1st WICI International Workshop, WImBI 2006, Beijing, China, December 15-16, 2006, Revised Selected and Invited Papers
the book include: workshop was the first in the field to focus on the interplay between (a) intelligent technologies, especially in the context of WI and (b) studies on human intelligence as explored in neuroscience, cognitive psychology, and brain science instrumentation.The book, as a volume in the Springer LNCS/LNAI state-of-the-art survey, will be a milestone publication, with research visions and blueprints, for com-puter scientists and practitioners at large in this exciting interdisciplinaryarea.
War related neuropsychological disease: Epilepsy
Among the consequences of war, the impact on the mental health of the civilian population is one of the most significant. Studies of the general population show a definite increase in the incidence and prevalence of mental disorders. Women are more affected than men. Other vulnerable groups are children, the elderly and the disabled. Prevalence rates are associated with the degree of trauma, and the availability of physical and emotional support. The use of cultural and religious coping strategies is frequent in developing countries. Epilepsy is a chronic non communicable disease of the brain that affects people of all ages. Around 50 million people worldwide have epilepsy, making it one of the most common neurological diseases globally. Nearly 80% of people with epilepsy live in low- and middle-income countries, it is estimated that up to 70% of people living with epilepsy could live seizure- free if properly diagnosed and treated.
Voltage-Sensitive Ion Channels : Biophysics of Molecular Excitability
Explores the complexity of a microscopic bit of matter that exists in a myriad of copies within our bodies, the voltage-sensitive ion channel. We seek to investigate the way in which these macromolecules make it possible for the long fibers of our nerve and muscle cells to conduct impulses. These integral components of cell membranes are marvels of nature's evolutionary adaptation. To understand them we must probe the boundaries of physics and chemistry. Since function is intimately related to structure, we examine the molecular structure of channels, focusing on physical principles that govern all matter. With the application of genetic methods, our knowledge of ion channels has broadened and deepened. In the hope that research can help ameliorate suffering, we discuss the diseases that arise from channel malfunctions due to genetic mutations.
Vocal Fold Paralysis
New therapeutic options and approaches have been developed based on an expanded knowledge of the underlying pathophysiology of vocal fold paralysis. The core of Vocal Fold Paralysis offers step-by-step descriptions and of the following therapies: vocal fold injection, medialization laryngoplasty, and arytenoid repositioning surgery. It also includes special topics such as reinnervation, vocal fold pacing, bilateral medialization, and pediatric and bilateral vocal fold paralysis. Vocal Fold Paralysis is a clinically useful reference for evaluation and treatment, as well as a summary of current knowledge and investigational approaches. This excellent guide fills a void within the field of otolaryngology and should not be missed by any otorhinolaryngologist, neurologist, phoniatrician or speech pathologist.
Vitamin D
There has been a growing interest in vitamin D during the last decades, which has boosted an increasing number of scientific papers on this topic. Vitamin D has a significant role in calcium homeostasis and metabolism, vitamin D deficiency is a worldwide health problem that affects not only musculoskeletal health but also a wide range of acute and chronic diseases, There is potentially a great upside to increasing the vitamin D status of children and adults worldwide for improving musculoskeletal health and reducing the risk of chronic illnesses, including some cancers, autoimmune diseases, infectious diseases, type 2 diabetes mellitus, neurocognitive disorders, and mortality. In addition, there are many evidences about the correlation between the vit.D and the levels of quality of life. Recently, taking of vit.D3 become in the guideline for cure and help the treatment of COVID-19 epidemic.
Visual Development
Research on visual development now spans a wide variety of disciplines encompassing biochemistry, anatomy, electrophysiology, psychophysics, clinical ophthalmology, and other related topics. It is difficult to present a thorough overview of such a broad range of topics in a simple, concise manner. However, Nigel Daw has masterfully accomplished this task in his book. It is well organized, informative, easy to read, and enjoyable.
Vertigo and Dizziness : Common Complaints
This short and concise, clinically-oriented book is for physicians of different specializations who treat patients with vertigo including neurologists and ENT specialists. Easy-to-use, it has an overview of the most important syndromes of vertigo, each with explanatory clinical descriptions and illustrations. Target market: Physicians of different specializations who treat patients with vertigo including neurologists, neurootologic specialists, neuroophthalmology, otolaryngology, head and neck surgery, ophthalmology and ENT specialists, and general medicine practitioners.
Vascular embolotherapy : A comprehensive approach ; Vol.2 : Oncology, trauma, gene therapy, vascular malformations, and neck
Endovascular embolization therapy has made remarkable progress during the past two decades, driven primarily by improvements in digital imaging, breakthroughs in microcatheter technology and coil design, and the development of new embolic materials. This is the second of two volumes that present the current state of the art in this exciting and growing field. Individual sections are devoted to vascular malformations, trauma and iatrogenic lesions, applications in oncology, indications in the head and neck region, gene therapy and pediatrics. High informational content is supplemented by detailed graphics, providing a comprehensive reference work for both experts and novices in the field.
Urodynamics
Urodynamics provides a simple yet practical guide to the functional investigation of patients with incontinence and voiding disturbances. The text makes clear the fundamental and vital contribution of urodynamic investigation to the management of patients with any form of lower urinary tract dysfunction. Concentrating on common clinical problems and the presenting symptom complexes rather than diagnosis, Urodynamics highlights the limitations and possible artifacts of investigation.
Unifying Themes in Complex Systems IV ; Proceedings of the Fourth International Conference on Complex Systems
In June of 2002, over 500 professors, students and researchers met in Boston, Massachusetts for the Fourth International Conference on Complex Systems. The attendees represented a remarkably diverse collection of fields: biology, ecology, physics, engineering, computer science, economics, psychology and sociology, The goal of the conference was to encourage cross-fertilization between the many disciplines represented and to deepen understanding of the properties common to all complex systems. This volume contains 43 papers selected from the more than 200 presented at the conference. Topics include: cellular automata, neurology, evolution, computer science, network dynamics, and urban planning.
Ultradian Rhythms from Molecules to Mind : A New Vision of Life
Timing exerted by oscillatory mechanisms are found throughout the biological world and their periods span a wide range from milliseconds, as in the action potential of n- rons and the myocytes, to the slow evolutionary changes that require thousands of generations. In this context, to understand the synchronization of a population of coupled oscillators is an important problem for the dynamics of physiology in living systems (Aon et al. , 2007a, b; Kuramoto, 1984; Strogatz, 2003; Winfree, 1967). Circadian rhythms, the most intensively studied, are devoted to measuring daily 24 h cycles. A variety of physiological processes in a wide range of eukaryotic organisms display circadian rhythmicity which is characterized by the following major properties (Anderson et al. , 1985; Edmunds, 1988): (i) stable, autonomous (self-sustaining) oscillations having a free-running period under constant envir- mental conditions of ca.
Two Minds : Intuition and Analysis in the History of Economic Thought
Intuition is warm and fuzzy, qualitative, not measurable. Economics, on the other hand, is quantitative, and if it is not a hard science, at least it is the "queen of the social sciences." It is, therefore, intuitively obvious, that intuition and economics are as if oil and water. The problem is, what is intuitively obvious is not always correct. And, there are two major reasons why intuition and economics are not like oil and water. First, economics concerns itself with decision making, and decisions are made in the brain. The human brain is the size of a grapefruit, weighing three pounds with approximately 180 billion neurons, each physically independent but interacting with the other neurons. What we call intuition is, like decision making, a natural information processing function of the brain. Second, despite the current emphasis on quantitative analysis and deductive logic there is a rich history of economists speaking about intuition. First, the human brain, specifically the neocortex, has a left and right hemisphere. The specialized analytical style of the left hemisphere and the specialized intuitive style of the right hemispheres complement each other.
Tutorials in Mathematical Biosciences I : Mathematical Neuroscience
Introduces some basic theories on computational neuroscience. Chapter 1 is a brief introduction to neurons, tailored to the subsequent chapters. Chapter 2 is a self-contained introduction to dynamical systems and bifurcation theory, oriented towards neuronal dynamics. The theory is illustrated with a model of Parkinson's disease. Chapter 3 reviews the theory of coupled neural oscillators observed throughout the nervous systems at all levels; it describes how oscillations arise, what pattern they take, and how they depend on excitory or inhibitory synaptic connections. Chapter 4 specializes to one particular neuronal system, namely, the auditory system. It includes a self-contained introduction, from the anatomy and physiology of the inner ear to the neuronal network that connects the hair cells to the cortex, and describes various models of subsystems.
Turning up the Heat on Pain : TRPV1 Receptors in Pain and Inflammation
In Chapter 1 of this volume, Janos Szolcsányi reviews this early research, which culminated with the seminal studies of Nicholas Jansco and his c- leagues in Hungary in the 1940s. Since then, capsaicin and related vanilloid c- pounds have played a prominent role in analgesia and inflammation investigations because of their ability to selectively activate a subpopulation of sensory neurons and produce sensations of pain and localized erythema.
Turmeric and curcumin for neurodegenerative diseases
Examines protective mechanisms of turmeric products and novel nanotechnological therapeutics and biomaterial design strategies to circumvent Alzheimer’s Disease, Parkinson’s, and liver diseases. With neurodegenerative and liver diseases posing a serious threat to health care systems worldwide, this book addresses how existing nanotechnology and therapeutic strategies have not been as successful in their treatment. In addition to discussing drawbacks, possible future perspectives to overcome these challenges are also examined. Chapters also focus on therapeutic efficacy and drug delivery systems, providing readers with a full summary of research in this field in one handy reference.
Tumors of the Spinal Canal
Presents a focused, case-oriented approach to a specific disease entity: tumors located within the spinal canal. Each tumor type constitutes its own chapter and additional chapters focus on more novel trends in the field, such as radiosurgery and minimally invasive surgical techniques. In each chapter, the authors provide expert opinions on preoperative goals, intraoperative techniques and decision-making, and postoperative paradigms, including surveillance guidelines and thresholds for initiating adjuvant therapy. The management of intradural tumors has become increasingly interdisciplinary, and one of the major goals of this text is to familiarize the treating neurosurgeon with the latest advances in both operative and non-operative strategies.
Tumors of the Brain and Spine
Highlights integrated care and focuses on treating the patient through the entire spectrum of the disease. This thorough, practical volume, which includes more than 70 illustrations and 30 tables, is an essential clinical guide for oncologists, surgeons, and other health care providers involved in the care of patients with central nervous system tumors.
