الصفحة 1
الصفحة 1
Intermittent fasting
The potential benefits of intermittent fasting are not limited to weight loss and weight management. Recent studies have shed light on its role in adaptive cellular responses that reduce oxidative damage and inflammation, optimize energy metabolism and bolster cellular protection. By reprogramming metabolic and stress resistance pathways, intermittent fasting has the possible ability to increase longevity and reduce aging. Studies on animals have given promising result that show how intermittent fasting help prevent and treat diseases like diabetes, cancers, heart disease and neurodegeneration. Major mechanisms hypothesized to link fasting regimens with human health: circadian biology and the gastrointestinal microbiota.
Ghrelin more than hunger hormone
Ghrelin is a stomach hormone that acts as an endogenous ligand of orphan G-protein-coupled receptor. Ghrelin is a 28-amino acid peptide existing in two major forms: n-octanoyl-modified ghrelin, which possesses an n-octanoyl modification on serine-3 and des-acyl ghrelin. Fatty acid modification of ghrelin is essential for ghrelin-induced growth hormone release from the pituitary and appetite stimulation. This acyl-modification of ghrelin is catalysed by ghrelin-O- acyl transferase recently identified.
Fasting and Immunity
Ramadan is the ninth month of the Islamic lunar calendar and is observed by Muslims as a month of fasting. All Muslim adults are expected to fast; nevertheless, certain subgroups, including sick, frail subjects, and pregnant women, among others, are exempted. Ramadan fasting has been shown to impact on body systems in different manners. The influence of Ramadan fasting on immune system regulation remains elusive; however, immune system changes, such as the modulation of body response to various infectious, stressful, and other harmful events, are of great interest during fasting.
