الصفحة 1
الصفحة 1
Uniformly Accelerating Charged Particles : A Threat to the Equivalence Principle
There has been a long debate about whether uniformly accelerated charges should radiate electromagnetic energy and how one should describe their worldline through a flat spacetime, i.e., whether the Lorentz-Dirac equation is right. There are related questions in curved spacetimes, e.g., do different varieties of equivalence principle apply to charged particles, and can a static charge in a static spacetime radiate electromagnetic energy? The problems with the LD equation in flat spacetime are spelt out in some detail here, and its extension to curved spacetime is discussed. Different equivalence principles are compared and some vindicated. The key papers are discussed in detail and many of their conclusions are significantly revised by the present solution.
Tsunamis and Hurricanes : A Mathematical Approach
This book presents new research on the mathematical description of tsunamis and hurricanes. The book uses the equivalence principle of solutions of nonlinear large gas dynamic waves and of solutions of water wave equations.
Translation between English and Arabic : A Textbook for Translation Students and Educators
This textbook provides a comprehensive resource for translation students and educators embarking on the challenge of translating into and out of English and Arabic. Combining a solid basis in translation theory with examples drawn from real texts including the Qu’ran, the author introduces a number of the problems and practical considerations which arise during translation between English and Arabic, equipping readers with the skills to recognise and address these issues in their own work through practical exercises.
The Austin Protocol Compiler
Presents a protocol specification language called the Timed Abstract Protocol (TAP) notation. This book will finally close the communication gap between the protocol verifiers and the protocol implementers. The TAP notation uses two types of semantics: an abstract semantics that appeals to the protocol verifiers and a concrete semantics which appeals to the protocol implementers. The Austin Protocol Compiler illustrates that the two types of semantics of TAP are equivalent. Thus, the correctness of TAP specification of some protocol, that is established based on the abstract semantics of TAP, is maintained when this specification is implemented based on concrete semantics of TAP. The equivalence between the abstract and concrete semantics of TAP suggests the following three-step method for developing a correct implementation of a protocol in this book: 1. Specify the protocol using the TAP notation. 2. Verify the correctness of the specification based on the abstract semantics of TAP 3. Implement the specification based on the concrete semantics of TAP
The ADME encyclopedia : A comprehensive guide on biopharmacy and pharmacokinetics
Covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties
Swiss Public Administration : Making the State Work Successfully
Swiss citizens approve of their government and the way democracy is practiced; they trust the authorities and are satisfied with the range of services Swiss governments provide. This is quite unusual when compared to other countries. This book provides insight into the organization and the functioning of the Swiss state. It claims that, beyond politics, institutions and public administration, there are other factors which make a country successful. The authors argue that Switzerland is an interesting case, from a theoretical, scientific and a more practice-oriented perspective. While confronted with the same challenges as other countries, Switzerland offers different solutions, some of which work astonishingly well.
Study of establishment of clinical research center in Syria
Drug products need to conform to the same standards of quality, efficacy and safety required of the originator's product. In addition, reasonable assurance must be provided that they are, as intended, clinically interchangeable with nominally equivalent market products. Most of the new pharmaceutical products that appear in the Syrian drug market are not of the original Source " BRAND ". Such medicines carry a different brand name than the original and named it" GENERIC ".We are talking about drugs in most cases where some active pharmaceutical ingredients are not protected by the invention, and its medical characteristics differ only slightly from the original drugs but the prices are cheaper. These drugs must have the same quality as the original medicines" BRAND" and contain all the characteristics of efficacy and safety.
Statistics Applied to Clinical Trials
This book explains classical statistical analyses of clinical trials,andaddresses relatively novel issues, including equivalence testing, interim analyses, sequential analyses, and meta-analyses, and provides a framework of the best statistical methods currently available for such purposes.
Problems and Theorems in Classical Set Theory
This is the first comprehensive collection of problems in set theory. Most of classical set theory is covered, classical in the sense that independence methods are not used, but classical also in the sense that most results come from the period between 1920-1970. Many problems are also related to other fields of mathematics such as algebra, combinatorics, topology and real analysis. The authors choose not to concentrate on the axiomatic framework, although some aspects are elaborated (axiom of foundation and the axiom of choice). Rather than using drill exercises, most problems are challenging and require work, wit, and inspiration. The problems are organized in a way that earlier problems help in the solution of later ones. For many problems, the authors trace the origin and provide proper references at the end of the solution.
Probabilistic Conditional Independence Structures
Conditional independence is a topic that lies between statistics and artificial intelligence. Probabilistic Conditional Independence Structures provides the mathematical description of probabilistic conditional independence structures; the author uses non-graphical methods of their description, and takes an algebraic approach. The monograph presents the methods of structural imsets and supermodular functions, and deals with independence implication and equivalence of structural imsets. Motivation, mathematical foundations and areas of application are included, and a rough overview of graphical methods is also given. In particular, the author has been careful to use suitable terminology, and presents the work so that it will be understood by both statisticians, and by researchers in artificial intelligence. The necessary elementary mathematical notions are recalled in an appendix. Probabilistic Conditional Independence Structures will be a valuable new addition to the literature, and will interest applied mathematicians, statisticians, informaticians, computer scientists and probabilists with an interest in artificial intelligence. The book may also interest pure mathematicians as open problems are included.
Pharmacokinetics and toxicokinetic considerations - Vol II ; 1st ed.
Explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists.
Pharmacokinetics : Basics to Applications
Covers all the essential elements of pharmacokinetics, from basics to applications. It describes authoritative equations and methods on pharmacokinetic evaluation procedures with their importance. Each chapter of the book is supplemented with numerous illustrations and figures for easy understanding of the subject. The book presents mathematical techniques, step- by-step descriptive equations, and applicable statistical analysis methods for the easy understanding of the topic. Further, it covers the preclinical applications and methods of pharmacokinetic aspects. The book also contains mathematical problems and questions related to pharmacokinetics for students. Special emphasis is on recent pharmacokinetic methods and their applications for managing clinical data and biostatistical approaches based on the current literature.
Pharmaceutical dissolution testing, bioavailability, and bioequivalence : Science, applications, and beyond
Delivers a comprehensive and up-to-date reference covering the established and emerging roles of dissolution testing in pharmaceutical drug development. After discussing the fundamentals of the subject, the included resources go on to explore common testing practices and methods, along with their associated challenges and issues, in the drug development life cycle. A thorough introduction to the fundamentals and essential applications of pharmaceutical dissolution testing. Comprehensive explorations of the foundations and drug development applications of bioavailability and bioequivalence. Practical discussions about solubility, dissolution, permeability, and classification systems in drug development. In-depth examinations of the mechanics of dissolution, including mathematical models and simulations. An elaborate assessment of biophysiologically relevant dissolution testing and IVIVCs, and their unique applications. A complete understanding of the methods, requirements, and global regulatory expectations pertaining to dissolution testing of generic drug products
Ordinal Optimization : Soft Optimization for Hard Problems
The purpose of this book is to address the difficulties of the optimization of complex systems via simulation models or other computation-intensive models involving possible stochastic effects and discrete choices. This book establishes distinct advantages of the "softer" ordinal approach for search-based type problems, analyzes its general properties, and shows the many orders of magnitude improvement in computational efficiency that is possible.
Ontology Matching
Euzenat and Shvaiko’s book is devoted to ontology matching as a solution to the semantic heterogeneity problem faced by computer systems. Ontology matching aims at finding correspondences between semantically related entities of different ontologies. These correspondences may stand for equivalence as well as other relations, such as consequence, subsumption, or disjointness, between ontology entities.
Hardware and software : Verification and testing ; 3rd International Haifa Verification Conference, HVC 2007, Haifa, Israel, October 23-25, 2007. Proceedings
These are the conference proceedings of the 4th Haifa Verifcation Conference, held October 27–30, 2008 in Haifa, Israel. This international conference is a unique venue that brings together leading researchers and practitioners of both formal and dynamic verifcation, for both hardware and software systems. This year’s conference extended the successes of the previous years, with a largejumpinthenumberofsubmitted papers. with many more high-quality papers than we had room to accept. Submissions came from 19 di?erent countries, re?ecting the growing international visibility of the conference. Of the 49 submissions, 43 were regular papers, 2 of which were later withdrawn, and 6 were tool papers. After a rigorous review process.
Handbook of philosophical logic ; Vol.13 ; 2nd ed.
in this book achapter on non-monotoniclogic a chapter on combinatory logic and calculus We feltat the time(1979)that non-monotonic logic was not ready fora chapter yet and that combinatory logic and calculus was toofar re-moved.1Non-monotonic logic is now a very major area of philosophi-cal logic, alongside default logics, labelled deductive systems,fibring log-ics, multi-dimensional,multi modal and substructur allogics. Intensive re-examinations offragments of classical logic have produced fresh insights,includingat time decision procedures and equivalence with non-classical systems
General Relativity
this book is a short and concise exposition of the central ideas of general relativity. Although the original audience was made up of mathematics students, the focus is on the chain of reasoning that leads to the relativistic theory from the analysis of distance and time measurements in the presence of gravity, rather than on the underlying mathematical structure. The geometric ideas - which are central to the understanding of the nature of gravity - are introduced in parallel with the development of the theory, the emphasis being on laying bare how one is led to pseudo-Riemannian geometry through a natural process of reconciliation of special relativity with the equivalence principle.
Exercises in Modules and Rings
This Problem Book offers a compendium of 639 exercises of varying degrees of difficulty in the subject of modules and rings at the graduate level. The material covered includes projective, injective, and flat modules, homological and uniform dimensions, noncommutative localizations and Goldie’s theorems, maximal rings of quotients, Frobenius and quasi-Frobenius rings, as well as Morita’s classical theory of category dualities and equivalences. Each of the nineteen sections begins with an introduction giving the general background and the theoretical basis for the problems that follow. All exercises are solved in full detail; many are accompanied by pertinent historical and bibliographical information, or a commentary on possible improvements, generalizations, and latent connections to other problems.
Electromagnetic Field Matter Interactions in Thermoelasic Solids and Viscous Fluids
This book in two parts delivers a thorough derivation of nonrelativistic interaction models of electromagnetic field theories with thermoelastic solids and viscous fluids, the intention being to derive unique representations for the observable field quantities. Part I, a revised and updated version of LNP 88 "Field Matter Interactions in Thermoelastic Solids," investigates the foundations and the equivalence of various formulations of the interaction of the electromagnetic field with thermoelastic solids in the classical continuum physics limit, while Part II extensively surveys two major fields of applications, namely, magnetoelastic instabilities and vibrations, and electrorheological fluids.
