الصفحة 1
الصفحة 1
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Molecular Biology of Metal Homeostasis and Detoxification : From Microbes to Man

One of the challenges faced by every cell as well as by whole organisms is to maintain appropriate concentrations of essential nutrient metals while excluding nonessential toxic metals. Toward that end, all organisms have developed mechanisms for metal homeostasis and detoxification to maintain metal levels within physiological limits. This book brings together current knowledge of the molecular basis of metal homeostasis and detoxification in various eukaryotic model systems, including yeasts, plants, and mammals. It focuses on the cellular systems controlling metal transport, intracellular distribution, and immobilization as well as on systems regulating metal-dependent transcription. In addition to environmental aspects (including phytoremediation), the book treats the pathophysiology of metal deficiency and overload in relation to disease.

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Erythropoietins and Erythropoiesis : Molecular, Cellular, Preclinical, and Clinical Biology

The book is divided into two sections: Background and Basic Science and Clinical Uses of Recombinant Erythropoietins. To begin, Israels and Israels describe the biology of red cells, the hierarchy of erythropoietic progenitor cells, their development to mature cells, and the effects of endogenous EPO on their development. Foote summarizes the historical interest in, and search for, an erythropoietic factor. Once EPO was identified,cloned,and expressed,the path was set for the study of other aspects of EPO biology both within e- thropoiesis and other cellular systems.

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Enhanced Radio Access Technologies for Next Generation Mobile Communication

Enhanced Radio Access Technologies for Next Generation Mobile Communication presents a comphrenhensive overview of the latest technology developments in the field Mobile Communications. This monograph focuses on the fundamentals of mobile communications technology and systems, including the history and service evolution of mobile communications and environments. Further to this, CDMA technology including spread spectrum, orthogonal and PN codes are introduced. Other important aspects include fundamentals of single carrier CDMA technologies, DS CDMA, Broadband CDMA with frequency domain equalizer, and multi-carrier CDMA technology for high speed data transmission including MC-DS/CDMA, MC-CDMA. Finally aspects of modern cellular systems such as cdma2000/1xEv-Do/1xEv-Dv and WCDMA/HSDPA are introduced and existing and developing wireless data services, such as Wi-Fi, Bluetooth, UWB, WiBro/Mobile WiMAX, and digital broadcasting services like DVB, DMB, ISDBT are described.

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Converged communications : Evolution from telephony to 5G mobile internet

The central theme of the book is to build deeper understanding about incremental technological progress by introducing both state of the art and their predecessor technologies. The book explores four main areas, including fixed telephone systems, data communication systems, mobile cellular systems, and IP multimedia systems. It clearly explains architectures, protocols, and functional procedures, and discusses a variety of topics ranging from physical layer processes to system level interactions. Converged ­Communications offers: In-depth treatments of fixed telephone and transmission systems, including operation of telephone exchanges and signaling systems Comprehensive explorations of data communication systems, including transmission of data over telephone lines and data network technologies, such as Ethernet and TCP/IP Incisive discussions of mobile cellular systems, including GSM, 3G, LTE, VoLTE and 5G Insightful analysis of incremental system evolution to justify various design choices made The book is supported with extensive online appendices, which covers communication system concepts, an overview of standardization, various technologies used in the past, state-of-the art technologies such as WLAN, cable modems, and FTTx, complementing the other systems described in the book which have evolved from the fixed telephone network.

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Life : An Introduction to Complex Systems Biology

What is life? Has molecular biology given us a satisfactory answer to this question? And if not, why, and how to carry on from there? This book examines life not from the reductionist point of view, but rather asks the question: what are the universal properties of living systems and how can one construct from there a phenomenological theory of life that leads naturally to complex processes such as reproductive cellular systems, evolution and differentiation? The presentation has been deliberately kept fairly non-technical so as to address a broad spectrum of students and researchers from the natural sciences and informatics.

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Communication Systems

Presents main concepts of mobile communication systems, both analog and digitalIntroduces concepts of probability, random variables and stochastic processes and their applications to the analysis of linear systemsIncludes five appendices covering Fourier series and transforms, GSM cellular systems and more

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Cell Engineering : Apoptosis

A reference on the development of cellular systems for the production of recombinant glycoproteins, gene and cell therapies, drug screening and tissue engineering. It intends to review the in-depth assessments of this type of programmed cell death. It is suitable for biotechnologists and researchers in apoptosis, cell biology, and cell culture.

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Biotechnology for the Future

One area that has attracted much attention is the use of cell factories for the production of a wide range of chemicals. This area illustrates very well the definition of biochemical engineering , and it has therefore been chosen as the focus of this volume. The use of cell factories for production of chemicals dates back to the production of penicillin, ethanol, acetone–butanol, glycerol and further to enzymes and other antibiotics. All these products were traditionally produced by cell factories that naturally produce these compounds. With the introduction of genetic engineering it has,This volume therefore contains chapters on concepts of metabolic engineering on detailed modeling of cellular systems

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Bionanotechnology : Proteins to Nanodevices

Bionanotechnology is the key integrative technology of the 21st century and aims to use the knowledge, gathered from the natural construction of cellular systems, for the advancement of science and engineering. Investigating the topology and communication processes of cell parts can lead to invention of novel biological devices with exciting applications. Though microscale to nanoscale research offers an excellent space for the development of futuristic technologies, a number of challenges must be overcome. Due to paucity of a dedicated literature on the protein based nanodevices we bring you this monograph that combines collective research works of scientists probing into this fascinating universe of bionanotechnology. The monograph has been written with an aim of surveying engineering design principles of biomolecular nanodevices, prototype nanodevices based on redox proteins, bacteriorhodopsins and natural fibers, and touching upon the future developments in the field.

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Bioinformatics research and applications ; 3rd International Symposium,ISBRA 2007, Atlanta, GA, USA, May 7-10, 2007, Proceedings

This book including clustering and classification, gene expression analysis, gene networks, genome analysis, motif finding, pathways, protein structure prediction, protein domain interactions, phylogenetics, and software tools.

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Bioinformatics research and applications : 4th International Symposium, ISBRA 2008, Atlanta, GA, USA, May 6-9, 2008. Proceedings

This book constitutes the refereed proceedings of the Fourth International Symposium on Bioinformatics Research and Applications, ISBRA 2008, held in Atlanta, GA, USA in May 2008.

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