الصفحة 1
الصفحة 1
Nimesulide - Actions and Uses
Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide. This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs.
Molluscs : From Chemo-ecological Study to Biotechnological Application
Marine molluscs are very promising candidates for a wide range of biotechnological applications. For example, they possess analgesic drugs more potent than morphine and very effective anticancer agents. The present book gives an up-to-date overview of the main classes of bioactive compounds from molluscs, moving from ecological observations, to chemical characterization, to biosynthesis, to large-scale synthesis, and to pharmacological applications. A truly outstanding international panel of experts from all continents provides complete coverage of the most stimulating topics related to molluscs. This knowledge of their history and current studies provides an open door to the future.
Ibuprofen : Pharmacology, Therapeutics and Side Effects
Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions. Over the past 40 years, ibuprofen has been proven to be as safe or even safer and also as effective as the established non-steroidal anti-inflammatory drugs (NSAIDs) and the coxibs. This well-written book reviews the pharmacology, clinical uses and the various adverse effects of Ibuprofen, the disposition and unique modes of action in relation to clinical effects of the drug as well as various formulations. The use of combinations with other drugs (e.g. paracetamol, codeine, caffeine) are critically assessed and the impact of natural products and Chinese Medicines on the safety of ibuprofen.
Future approaches for safe and effective pain management
Pain is defined as an unpleasant sensory and emotional experience that is associated with actual or potential tissue damage or described in terms of such damage. It is subjective and considered an important physiological mechanism by which humans prevent themselves from developing tissue injury. However, pain patients do not respond to treatment in the same way, which makes it challenging to issue a consistent treatment for all pain conditions. Excessive pain can markedly increase psychological health problems and decrease health‐related quality of life; therefore, pain should be managed appropriately by analgesics. Analgesics act in various ways on the peripheral and central pain pathways and are regarded as one of the most valuable but equally dangerous groups of medications. Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined. Pain severities as well as responses to analgesics, can also be very variable among sufferer.
Essentials of Pharmacology for Dentistry
Pharmacology, the science of drugs (medicines), is a highly dynamic discipline with concepts and priority drugs changing rapidly. Its relevance to all health professionals (including dentists) cannot be over emphasized. Practice of dentistry utilizes drugs both as primary treatment modality, as well as facilitator of/adjuvant to dental procedures. Dentists routinely prescribe analgesics and antibiotics, apply antiseptics and other locally acting drugs, and inject local anaesthetics. Further, many dental patients could be receiving other medication that may have orodental implications or may interact with drugs prescribed by the dentist. Occasionally, dentists have to manage a medical emergency which may arise during a dental procedure or in their clinic. As such, a broad knowledge of pharmacology along with focus on aspects is needed by the dentist.
Effect of Clove essential oil and Rosemary aqueous extract for future promising triple acting gel
In this study, antimicrobial properties of rosemary essential oil (Rosmarinus officinalis-REO), rosemary aqueous extract, clove essential oil (Syzygium aromaticum-CEO) and their mixtures (REO/CEO) at 10% and 20% concentration for each one have been evaluated. The agar well diffusion method has been used for screening the antimicrobial activity against Staphylococcus aureus, Staphylococcus albus, Streptococcus, Enterococcus Salmonella, Escherichia coli, Acinetobacter, Pseudomonas aeruginosa, Candida albicans In Staph. Aureus, Salmonella, E.coli, Acinetobacter and p.aeruginosa...
Drugs in palliative care
While palliative care has adopted a holistic approach to treatment / medication-driven symptom management ostensibly forms the critical aspect of care. Prescribing in palliative care can be extremely complex because the patient may often have comorbidity / or occasionally multimorbidity. The associated polypharmacy further complicates the pharmacological management of symptoms being caused by the palliative condition. This can be daunting for healthcare professionals and can negatively impact upon the effectiveness of care provided. Fully revised and updated / the third edition of Drugs in Palliative Care provides a detailed / yet concise overview of topics that are encountered in palliative care clinical practice. The book will appeal to a variety of healthcare professionals involved in the provision of palliative care and medicines information.
Drug Discovery and Evaluation
The 3rd edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal, and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described.
Drug Delivery Systems
Expands on the previous editions with a discussion of new and updated methods used to study drug delivery. Chapters cover topics such as drug delivery in cancer and intrathecal delivery of analgesics in humans. The increasing role of nanobiotechnology is reflected in eight of the sixteen chapters that include synthesis of gold nanoparticles; targeted siRNA delivery; and lipid nanocarriers. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Contemporary dental pharmacology : Evidence-based considerations ; 2nd ed.
Aims to equip practitioners with a sound understanding of both the scientific evidence for various interventions and the comparative efficacy of those interventions. The focus is on the drugs most commonly used in conjunction with dental treatment, including local anesthetics, analgesics, antibiotics, sedatives, and drugs for the management of medical emergencies. Summaries of the scientific evidence from the available published literature are provided, with assessment of the level and quality of the evidence base.
Contemporary dental pharmacology : Evidence-based considerations ; 1st ed.
This book on current approaches to the use of drugs in dentistry aims to equip practitioners with a sound understanding of both the scientific evidence for various interventions and the comparative efficacy of those interventions. The focus is on the drugs most commonly used in conjunction with dental treatment, including local anesthetics, analgesics, antibiotics, sedatives, and drugs for the management of medical emergencies.
Botulinum Toxin Treatment in Surgery, Dentistry, and Veterinary Medicine
This book provides up-to-date information on botulinum toxin therapy in surgical fields. It is also the only book in the market that provides information on botulinum toxin therapy in dentistry and veterinary medicine and furnishes the latest information.
Analgesia
Analgesics are among the oldest drugs described, albeit not necessarily for medicinaluse. Forexample,theSumeriansisolatedopioids(probablyfortheir euphoric effects) in the third millennium b. c. and the use of willow bark (salicin) for fever was ?rst reported in the eighteenth century. Both types of drugs are still in use, but today they are supplemented by a wide array of substances ranging from antidepressants to ion channel blockers. Not all of theseareprescribedbyphysicians. Manycompoundsaresoldoverthecounter and thus available to the public for self-medication. As a result, analgesics are also the most misused class of drugs and are the culprit for a multitude of healthproblemsdueto untoward sideeffects. Thisvolumeattemptstosummarizethecurrentstateofknowledgeonme- anisms underlying the various effects of these drugs, their side effect pro?les, and their indications and contraindications in clinical use.
