الصفحة 1
الصفحة 1
Palladium in Organic Synthesis
Presents a number of accounts and reviews on the novel Pd-catalyzed reactions discovered mainly in the last five years. The book covers Pd-catalyzed reactions that are new – entirely different from the more standard ones. Topics such as new reactions involving ß-carbon elimination and formation of palladacycles as key reactions, cross-coupling of unactivated alkyl electrophiles with organometallic compounds, arylation via C-H bond cleavage, Pd/norbornene-catalyzed aromatic functionalizations, three-component cyclizations of allenes, use of N-heterocyclic carbenes as ligands, asymmetric reactions catalyzed by Pd(II) compounds such as Lewis acids, cycloadditions of arynes and alkynes, and nucleophilic attack by Pd species are surveyed in detail by researchers who have made important contributions to these fields. The book addresses graduate students majoring in organic synthesis and researchers in academic and industrial institutes.
Organic Chemistry ; 9th ed.
Structure and Bonding / Polar Covalent Bonds; Acids and Bases / Organic Compounds: Alkanes and Their Stereochemistry / Organic Compounds: Cycloalkanes and Their Stereochemistry / Stereochemistry at Tetrahedral Centers / An Overview of Organic Reactions / Alkenes: Structure and Reactivity / Alkenes: Reactions and Synthesis / Alkynes: An Introduction to Organic Synthesis / Organohalides / Reactions of Alkyl Halides: Nucleophilic Substitutions and Eliminations / Structure Determination: Mass Spectrometry and Infrared Spectroscopy / Structure Determination: Nuclear Magnetic Resonance Spectroscopy / Conjugated Compounds and Ultraviolet Spectroscopy / Benzene and Aromaticity / Chemistry of Benzene: Electrophilic Aromatic Substitution / Alcohols and Phenols / Ethers and Epoxides; Thiols and Sulfides / Aldehydes and Ketones: Nucleophilic Addition Reactions / Carboxylic Acids and Nitriles / Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution Reactions / Carbonyl Alpha-Substitution Reactions / Carbonyl Condensation Reactions / Amines and Heterocycles / Biomolecules: Carbohydrates / Biomolecules: Amino Acids, Peptides, and Proteins / Biomolecules: Lipids / Biomolecules: Nucleic Acids / The Organic Chemistry of Metabolic PathwaysOrbitals and Organic Chemistry: Pericyclic Reactions Synthetic / Polymers
Metal Catalyzed Reductive C-C Bond Formation : A Departure from Preformed Organometallic Reagents
The prototypical catalytic reductive C–C bond formations, the Fischer-Tropsch reaction [1] and alkene hydroformylation [2], were discovered in 1922 and 1938, respectively [3,4]. These processes, which involve reductive coupling to carbon monoxide, have long been applied to the industrial manufacture of commodity chemicals [5]. Notably, alkene hydroformylation, also known as the oxo-synthesis, has emerged as the largest volume application of homogeneous metal catalysis, accounting for the production of over 7 million metrictons of aldehyde annually. Despite the impact of these prototypical reductive C–C bond formations, this field of research lay fallow for several decades.
Addition Reactions with Unsaturated Hydrocarbons
Addition Reactions with Unsaturated Hydrocarbons presents an up-to-date overview of modern methods that utilize reactions of unsaturated hydrocarbons as building blocks of organic synthesis, covering the conceptual and practical knowledge required for designing atom-efficient reactions to synthesize functionalized molecules. This authoritative volume discusses homo-dimerization and cross-dimerization of alkynes and/or alkenes, synthesis of carbonyl compounds from the hydration of alkynes, cycloadditions of alkynes and alkenes for the synthesis of carbocycles and heterocycles.
